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SV2002000244A - Metodos y compuestos para inhibir mrp1 ref.x-13353 - Google Patents

Metodos y compuestos para inhibir mrp1 ref.x-13353

Info

Publication number
SV2002000244A
SV2002000244A SV2000000244A SV2000000244A SV2002000244A SV 2002000244 A SV2002000244 A SV 2002000244A SV 2000000244 A SV2000000244 A SV 2000000244A SV 2000000244 A SV2000000244 A SV 2000000244A SV 2002000244 A SV2002000244 A SV 2002000244A
Authority
SV
El Salvador
Prior art keywords
ref
compounds
methods
mrp1
inhibit
Prior art date
Application number
SV2000000244A
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Jeffrey Daniel Cohen
Joseph Michael Gruber
Douglas Webb Johnson
Louis Nickolaus Jungheim
Julian Stanley Kroin
Ho-Shen Lin
Mark Christopher Lohman
Brian Stephen Muehl
Bryan Hurst Norman
Vinod Francis Patel
Michael Enrico Richett
Kenneth Jeff Thrasher
Sreenivasarao Vepachedu
Qiuping Wang
Wesley Todd White
Yongping Xie
York Jeremy Schlunburg
Brandon Lee Parkhurst
Peter Ambrose Lander
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SV2002000244A publication Critical patent/SV2002000244A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE ADEMAS A UN PROCEDIMIENTO PARA LA INHIBICION DE LA MRP1 EN UN MAMIFERO, QUE COMPRENDE LA ADMINISTRACION A UN MAMIFERO NECESITADO DE ELLO DE UNA CANTIDAD EFICAZ SE UN COMPUESTO DE FORMULA I.
SV2000000244A 1999-12-22 2000-12-21 Metodos y compuestos para inhibir mrp1 ref.x-13353 SV2002000244A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17137399P 1999-12-22 1999-12-22
US22607600P 2000-08-17 2000-08-17
US23453900P 2000-09-22 2000-09-22

Publications (1)

Publication Number Publication Date
SV2002000244A true SV2002000244A (es) 2002-07-16

Family

ID=27389968

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2000000244A SV2002000244A (es) 1999-12-22 2000-12-21 Metodos y compuestos para inhibir mrp1 ref.x-13353

Country Status (12)

Country Link
EP (1) EP1250340B1 (es)
JP (1) JP2003518125A (es)
AT (1) ATE282623T1 (es)
AU (1) AU2251901A (es)
CA (1) CA2395513A1 (es)
CO (1) CO5261493A1 (es)
DE (1) DE60016039T2 (es)
ES (1) ES2233487T3 (es)
PE (1) PE20011085A1 (es)
PT (1) PT1250340E (es)
SV (1) SV2002000244A (es)
WO (1) WO2001046199A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1301518A1 (en) * 2000-06-14 2003-04-16 Eli Lilly And Company Tricyclic compounds as mrp1-inhibitors
EP1296953A2 (en) 2000-06-23 2003-04-02 Eli Lilly And Company Methods and compounds for inhibiting mrp1
WO2004016741A2 (en) * 2002-08-14 2004-02-26 Ppd Discovery, Inc. Prenylation inhibitors containing dimethyl-cyclobutane and methods of their synthesis and use
CA2537841A1 (en) 2003-09-06 2005-03-24 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
ITMI20032121A1 (it) * 2003-11-04 2005-05-05 Dinamite Dipharma Spa In Forma Abbr Eviata Dipharm Procedimento per la preparazione di imiquimod e suoi intermedi
US7230002B2 (en) 2004-02-03 2007-06-12 Glenmark Pharmaceuticals Ltd. Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof
WO2005075426A1 (en) * 2004-02-03 2005-08-18 Glenmark Pharmaceuticals Ltd. Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
WO2005118583A1 (en) * 2004-05-28 2005-12-15 Millennium Pharmaceuticals, Inc. 2, 5-dihydro-pyrazolo`4, 3-c!quinolin-4-ones as chk-1 inhibitors
WO2006011035A1 (en) * 2004-07-23 2006-02-02 Glenmark Pharmaceuticals Ltd. Novel dipeptidyl peptidase iv inhibitors; process for their preparation and compositions containing them
KR20070073887A (ko) 2004-10-12 2007-07-10 그렌마크 파머수티칼스 에스. 아. 신규한 디펩티딜 펩티다제 ⅳ 억제제, 이를 함유하는약제학적 조성물, 및 이의 제조공정
JP4845372B2 (ja) * 2004-11-30 2011-12-28 広栄化学工業株式会社 光学活性２−ヒドロキシエステル化合物の製造方法
RU2524949C2 (ru) * 2007-11-23 2014-08-10 Лео Фарма А/С Новые циклические углеводородные соединения для лечения заболеваний
US20090246198A1 (en) * 2008-03-31 2009-10-01 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors and methods of use thereof
WO2012000498A1 (en) * 2010-06-30 2012-01-05 Leo Pharma A/S New polymorphic form of a calcimimetic compound
CN102958908A (zh) * 2010-06-30 2013-03-06 利奥制药有限公司 钙敏感受体激动化合物的新多晶型
TW201534586A (zh) 2013-06-11 2015-09-16 Orion Corp 新穎ｃｙｐ１７抑制劑／抗雄激素劑
CN104230744B (zh) * 2014-09-01 2016-06-08 湖南尔康制药股份有限公司 一种替加环素原料药的生产方法
BR112017008809A2 (pt) 2014-11-05 2017-12-19 Flexus Biosciences Inc agentes imunorreguladores
UY36390A (es) 2014-11-05 2016-06-01 Flexus Biosciences Inc Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
CN112409207B (zh) * 2019-08-22 2022-11-22 新发药业有限公司 一种醚菌胺的制备方法
CN114890940A (zh) * 2022-04-21 2022-08-12 嘉兴瑞驰生物科技有限公司 一种6-甲氧基-2-吡啶甲酸的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980608A (en) * 1998-01-07 1999-11-09 Advanced Technology Materials, Inc. Throughflow gas storage and dispensing system
PL343312A1 (en) * 1998-04-08 2001-08-13 Lilly Co Eli Methods for inhibiting mrp1
HUP0101508A3 (en) * 1998-04-08 2002-04-29 Lilly Co Eli Isoxazolo[3,4-c]quinoline derivatives, their use and pharmaceutical compositions containing them
TR200002804T2 (tr) * 1998-04-08 2001-02-21 Eli Lilly And Company MRP1 inhibe etmek için yöntemler

Also Published As

Publication number Publication date
DE60016039D1 (de) 2004-12-23
EP1250340A1 (en) 2002-10-23
DE60016039T2 (de) 2005-08-11
PT1250340E (pt) 2005-04-29
PE20011085A1 (es) 2001-10-24
WO2001046199A1 (en) 2001-06-28
CO5261493A1 (es) 2003-03-31
AU2251901A (en) 2001-07-03
ES2233487T3 (es) 2005-06-16
CA2395513A1 (en) 2001-06-28
ATE282623T1 (de) 2004-12-15
JP2003518125A (ja) 2003-06-03
EP1250340B1 (en) 2004-11-17

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