SK872002A3 - New vitamin d derivatives with cyclic substructures in the side chains, method and intermediates for their production and their use in the preparation of medicaments - Google Patents

New vitamin d derivatives with cyclic substructures in the side chains, method and intermediates for their production and their use in the preparation of medicaments Download PDF

Info

Publication number: SK872002A3
Authority: SK; Slovakia
Prior art keywords: secochola; homo; triol; diene; triene
Prior art date: 1999-07-23

Application number

SK87-2002A

Other languages

English (en)

Slovak (sk)

Inventor

Andreas Steinmeyer

Katica Schwarz

Claudia Giesen

Martin Haberey

Marianne Fahnrich

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-23

Filing date

2000-07-24

Publication date

2002-09-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7916563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK872002(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-07-24 Application filed by Schering Ag filed Critical Schering Ag

2002-09-10 Publication of SK872002A3 publication Critical patent/SK872002A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
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- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
- B21C25/00—Profiling tools for metal extruding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
- B21C25/00—Profiling tools for metal extruding
- B21C25/10—Making tools by operations not covered by a single other subclass
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Mechanical Engineering (AREA)
Obesity (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oncology (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)

SK87-2002A 1999-07-23 2000-07-24 New vitamin d derivatives with cyclic substructures in the side chains, method and intermediates for their production and their use in the preparation of medicaments SK872002A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19935771A DE19935771A1 (de)	1999-07-23	1999-07-23	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
PCT/EP2000/007104 WO2001007405A2 (fr)	1999-07-23	2000-07-24	Nouveaux derives de vitamine d comportant des sous-structures cycliques dans les chaines laterales, procede de fabrication et produits intermediaires, et utilisation dans la preparation de produits pharmaceutiques

Publications (1)

Publication Number	Publication Date
SK872002A3 true SK872002A3 (en)	2002-09-10

Family

ID=7916563

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK87-2002A SK872002A3 (en)	1999-07-23	2000-07-24	New vitamin d derivatives with cyclic substructures in the side chains, method and intermediates for their production and their use in the preparation of medicaments

Country Status (29)

Country	Link
US (2)	US6603031B1 (fr)
EP (2)	EP1362848A1 (fr)
JP (1)	JP2003505447A (fr)
KR (1)	KR100713744B1 (fr)
CN (1)	CN1372543A (fr)
AT (1)	ATE316073T1 (fr)
AU (1)	AU773673B2 (fr)
BG (1)	BG106334A (fr)
BR (1)	BR0013175A (fr)
CA (1)	CA2376465A1 (fr)
CZ (1)	CZ2002150A3 (fr)
DE (2)	DE19935771A1 (fr)
DK (1)	DK1210327T3 (fr)
EA (1)	EA004703B1 (fr)
EE (2)	EE05027B1 (fr)
ES (1)	ES2254222T3 (fr)
HR (1)	HRP20020161A2 (fr)
HU (1)	HUP0202015A3 (fr)
IL (2)	IL147634A0 (fr)
MX (1)	MXPA01013330A (fr)
NO (1)	NO20020330L (fr)
NZ (1)	NZ515891A (fr)
PL (1)	PL353102A1 (fr)
SI (1)	SI1210327T1 (fr)
SK (1)	SK872002A3 (fr)
UA (1)	UA82307C2 (fr)
WO (1)	WO2001007405A2 (fr)
YU (1)	YU4402A (fr)
ZA (1)	ZA200201482B (fr)

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US6566353B2 (en) *	1996-12-30	2003-05-20	Bone Care International, Inc.	Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US20020128240A1 (en) *	1996-12-30	2002-09-12	Bone Care International, Inc.	Treatment of hyperproliferative diseases using active vitamin D analogues
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP2070911A2 (fr)	2000-07-18	2009-06-17	Bone Care International, Inc.	1Alpha-hydroxy vitamine D stabilisée
AU2003271171A1 (en)	2002-10-10	2004-05-04	Masato Shimizu	2,2-DI-SUBSTITUTED 1Alpha,25-DIHYDROXY-19-NORVITAMIN D DERIVATIVE
US7351869B2 (en) *	2002-11-18	2008-04-01	Teva Pharmaceutical Industries Ltd	Crystallization method for purification of calcipotriene
WO2005027916A1 (fr) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Compositions pharmaceutiques et methodes de traitement consistant en des associations d'un derive de la 2-alkylidene-19-nor-vitamine d et d'un inhibiteur de l'aromatase
JP2007505884A (ja) *	2003-09-19	2007-03-15	ファイザー・プロダクツ・インク	骨減少症又は男性の骨粗しょう症の治療のための２−アルキリデン−１９−ノル−ビタミンｄ誘導体
WO2005027930A1 (fr) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Derives de la 2-alkylidene-19-nor-vitamine d pour le traitement de l'osteosarcome
WO2005027922A1 (fr) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Derives de la 2-alkylidene-19-nor-vitamine d pour le traitement de l'hypogonadisme ou de l'andropause
RU2326695C2 (ru) *	2003-09-19	2008-06-20	Пфайзер Продактс Инк.	Фармацевтические композиции и способы, включающие комбинации 2-алкилиденовых производных 9-нор-витамина d и бисфосфоната
WO2005027918A1 (fr) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Compositions pharmaceutiques et methodes de traitement consistant en des associations d'un derive de la 2-alkylidene-19-nor-vitamine d et d'un inhibiteur de la cyclooxygenase-2
WO2005074389A2 (fr) *	2004-02-03	2005-08-18	Chugai Pharmaceutical Co Ltd	Procede de synthese de composes de vitamine d et intermediaires pour la synthese des composes
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
DE102005017775A1 (de) *	2005-04-13	2006-10-19	Schering Ag	Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins
GB0608806D0 (en) *	2006-05-04	2006-06-14	Lipopeptide Ab	Combination therapy product and uses thereof
JP2010502624A (ja) *	2006-08-29	2010-01-28	テバファーマシューティカルインダストリーズリミティド	低ｐＨ親和性を有するコルチコステロイド化合物及びビタミンＤ含有化合物を含む安定な薬理活性組成物
US9290447B2 (en)	2011-05-03	2016-03-22	Wisconsin Alumni Research Foundation	(20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
US10548908B2 (en)	2016-09-15	2020-02-04	Nostopharma, LLC	Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

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SG70010A1 (en)	1996-05-23	2000-01-25	Hoffmann La Roche	Fluorinated vitamin d3 analogs
US5945410A (en) *	1997-03-17	1999-08-31	Wisconsin Alumni Research Foundation	2-alkyl-19-nor-vitamin D compounds
MA26481A1 (fr)	1997-04-21	2004-12-20	Hoffmann La Roche	Derives d'arylsecocholadiene
AU2413499A (en)	1997-12-17	1999-07-05	Schering Aktiengesellschaft	Vitamin d derivatives with phosphorous atoms in the side chains
EP0927721A1 (fr) *	1997-12-17	1999-07-07	Schering Aktiengesellschaft	Nouveaux dérivés de la vitamine D ayant des atomes de phosphore sur les chaines latérales, intermédiaires pour leur préparation et leur utilisation pour la préparation de médicaments
EP0957098A1 (fr) *	1998-05-14	1999-11-17	F. Hoffmann-La Roche Ag	Intermédiaires pour la synthèse de métabolites de la 3-épi vitamine D3 et analogues
US6177688B1 (en) *	1998-11-24	2001-01-23	North Carolina State University	Pendeoepitaxial gallium nitride semiconductor layers on silcon carbide substrates
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
DE20118652U1 (de) *	2000-12-19	2002-03-21	Dräger Safety AG & Co. KGaA, 23560 Lübeck	Vorrichtung zur Befestigung von Augengläsern

1999
- 1999-07-23 DE DE19935771A patent/DE19935771A1/de not_active Withdrawn
2000
- 2000-07-24 US US09/624,608 patent/US6603031B1/en not_active Expired - Fee Related
- 2000-07-24 EP EP03090212A patent/EP1362848A1/fr not_active Withdrawn
- 2000-07-24 KR KR1020027000905A patent/KR100713744B1/ko not_active Expired - Fee Related
- 2000-07-24 CZ CZ2002150A patent/CZ2002150A3/cs unknown
- 2000-07-24 EP EP00962278A patent/EP1210327B1/fr not_active Expired - Lifetime
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- 2000-07-24 AT AT00962278T patent/ATE316073T1/de not_active IP Right Cessation
- 2000-07-24 WO PCT/EP2000/007104 patent/WO2001007405A2/fr not_active Ceased
- 2000-07-24 AU AU74072/00A patent/AU773673B2/en not_active Ceased
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- 2000-07-24 SK SK87-2002A patent/SK872002A3/sk not_active Application Discontinuation
- 2000-07-24 SI SI200030802T patent/SI1210327T1/sl unknown
- 2000-07-24 CN CN00810762A patent/CN1372543A/zh active Pending
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- 2000-07-24 DE DE50012087T patent/DE50012087D1/de not_active Expired - Fee Related
- 2000-07-24 DK DK00962278T patent/DK1210327T3/da active
2002
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Also Published As

Publication number	Publication date
CZ2002150A3 (cs)	2002-05-15
EP1210327B1 (fr)	2006-01-18
KR100713744B1 (ko)	2007-05-02
EE200200036A (et)	2003-04-15
EA200200096A1 (ru)	2002-06-27
EE200800025A (et)	2008-06-16
BR0013175A (pt)	2002-04-02
WO2001007405A2 (fr)	2001-02-01
IL147634A (en)	2006-10-31
YU4402A (sh)	2005-03-15
MXPA01013330A (es)	2002-07-09
EE05027B1 (et)	2008-06-16
HUP0202015A2 (en)	2002-10-28
UA82307C2 (uk)	2008-04-10
US7115758B2 (en)	2006-10-03
SI1210327T1 (sl)	2006-04-30
HRP20020161A2 (en)	2005-10-31
EP1362848A1 (fr)	2003-11-19
US6603031B1 (en)	2003-08-05
BG106334A (bg)	2002-06-28
CN1372543A (zh)	2002-10-02
EA004703B1 (ru)	2004-06-24
NO20020330L (no)	2002-03-22
WO2001007405A3 (fr)	2002-03-28
ZA200201482B (en)	2003-07-30
DE50012087D1 (de)	2006-04-06
HUP0202015A3 (en)	2004-04-28
CA2376465A1 (fr)	2001-02-01
ATE316073T1 (de)	2006-02-15
US20030149006A1 (en)	2003-08-07
AU773673B2 (en)	2004-06-03
NO20020330D0 (no)	2002-01-22
ES2254222T3 (es)	2006-06-16
JP2003505447A (ja)	2003-02-12
DK1210327T3 (da)	2006-04-03
IL147634A0 (en)	2002-08-14
PL353102A1 (en)	2003-10-20
EP1210327A2 (fr)	2002-06-05
AU7407200A (en)	2001-02-13
KR20020022780A (ko)	2002-03-27
NZ515891A (en)	2004-03-26
DE19935771A1 (de)	2001-02-01

Publication	Publication Date	Title
SK872002A3 (en)	2002-09-10	New vitamin d derivatives with cyclic substructures in the side chains, method and intermediates for their production and their use in the preparation of medicaments
US6372731B1 (en)	2002-04-16	Vitamin D derivatives with C-25 substituents, process for their preparation, intermediate products and their use in preparing medicaments
US5585368A (en)	1996-12-17	20-position modified pharmaceutically active vitamin D series compounds
US5583125A (en)	1996-12-10	25-Carboxylic acid derivatives in the vitamin D series, process for their production, intermediate products for these processes, pharmaceutical preparations containing these derivatives as well as their use for the production of pharmaceutical agents
SK146498A3 (en)	1999-04-13	New vitamin d derivatives with carbo- or heterocyclic substituents at c-25, a process for their production, intermediate products and their use for producing medicaments
JP2006523239A (ja)	2006-10-12	２−プロピリデン−１９−ノル−ビタミンｄ化合物
US7538098B2 (en)	2009-05-26	19-nor-vitamin D analogs with 1,2 or 3,2 heterocyclic ring
NZ529816A (en)	2005-07-29	New vitamin D derivatives with cyclic substructures in the side chains, process and intermediate products for their production, and the use for the production of pharmaceutical agents
JPH06329622A (ja)	1994-11-29	ヨードビタミンｄ３化合物類及びその調製方法

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2010-11-08	FC9A	Refused patent application