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SK156395A3 - Peptid compounds, their manufacturing method and application - Google Patents

Peptid compounds, their manufacturing method and application Download PDF

Info

Publication number
SK156395A3
SK156395A3 SK1563-95A SK156395A SK156395A3 SK 156395 A3 SK156395 A3 SK 156395A3 SK 156395 A SK156395 A SK 156395A SK 156395 A3 SK156395 A3 SK 156395A3
Authority
SK
Slovakia
Prior art keywords
compounds
fvii
peptides
peptide
cells
Prior art date
Application number
SK1563-95A
Other languages
English (en)
Slovak (sk)
Inventor
Kjell S Sakariassen
Ross W Stephens
Original Assignee
Hafslund Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939312601A external-priority patent/GB9312601D0/en
Application filed by Hafslund Nycomed As filed Critical Hafslund Nycomed As
Publication of SK156395A3 publication Critical patent/SK156395A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK1563-95A 1993-06-18 1994-06-17 Peptid compounds, their manufacturing method and application SK156395A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939312601A GB9312601D0 (en) 1993-06-18 1993-06-18 Peptides
GB9409335A GB9409335D0 (en) 1993-06-18 1994-05-10 Peptides
PCT/GB1994/001315 WO1995000541A1 (fr) 1993-06-18 1994-06-17 Peptides derives du facteur vii

Publications (1)

Publication Number Publication Date
SK156395A3 true SK156395A3 (en) 1996-06-05

Family

ID=26303086

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1563-95A SK156395A3 (en) 1993-06-18 1994-06-17 Peptid compounds, their manufacturing method and application

Country Status (15)

Country Link
US (1) US5962418A (fr)
EP (1) EP0703923B1 (fr)
JP (1) JPH08511794A (fr)
CN (1) CN1125450A (fr)
AT (1) ATE171950T1 (fr)
CA (1) CA2164422A1 (fr)
CZ (1) CZ334095A3 (fr)
DE (1) DE69413817T2 (fr)
DK (1) DK0703923T3 (fr)
FI (1) FI956055L (fr)
HU (1) HUT74873A (fr)
NO (1) NO955067L (fr)
NZ (1) NZ267453A (fr)
SK (1) SK156395A3 (fr)
WO (1) WO1995000541A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
GB9425381D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
GB9425380D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
WO1999013062A1 (fr) * 1997-09-09 1999-03-18 Nycomed Imaging As Fragments de facteur vii, leurs analogues, et leur utilisation dans le traitement de troubles lies a la coagulation du sang
WO1999013063A1 (fr) * 1997-09-09 1999-03-18 Nycomed Imaging As Fragments du facteur vii et leurs analogues, utilisation dans le traitement des troubles dus aux caillots sanguins
EP0987274A1 (fr) 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Inhibiteurs du facteur VIIa
AU5062100A (en) * 1999-06-14 2001-01-02 Novo Nordisk A/S Fviia/tf activity inhibiting compounds
JP2003503426A (ja) 1999-07-02 2003-01-28 ジェネンテック・インコーポレーテッド ＦＶＩＩａアンタゴニスト
US7164002B2 (en) 2002-02-06 2007-01-16 Genentech, Inc. FVIIa antagonists
US20060257359A1 (en) * 2005-02-28 2006-11-16 Cedric Francois Modifying macrophage phenotype for treatment of disease
EP3402537B1 (fr) 2016-01-15 2021-01-06 Rigshospitalet Imagerie par tep quantitative de l'expression du facteur tissulaire employant un facteur vii à site actif inhibé marqué au 18f
US20190358351A1 (en) 2016-11-17 2019-11-28 Minerva Imaging Aps 177-lu labeled active site inhibited factor vii

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496927A (en) * 1985-02-04 1996-03-05 Merrell Pharmaceuticals Inc. Peptidase inhibitors
DE3684633D1 (de) * 1985-04-16 1992-05-07 Suntory Ltd Dipeptid-derivate von fettsaeure, verfahren zu ihrer herstellung, heilmittel, das sie enthaelt und anwendung.
US5087564A (en) * 1985-06-20 1992-02-11 Monsanto Company Release of recombinant peptides from polypeptides using V8 endopeptidase
US5047401A (en) * 1985-09-09 1991-09-10 Board Of Regents, The University Of Texas System Use of dipeptide alkyl esters to treat GVHD
WO1990003390A1 (fr) * 1988-09-23 1990-04-05 Corvas, Inc. Inhibiteurs peptidyles de l'initiation de la coagulation
JP3330932B2 (ja) * 1990-01-29 2002-10-07 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 抗凝固剤タンパク質
DE4007902A1 (de) * 1990-03-13 1991-09-19 Behringwerke Ag Synthetische peptide, die sequenzen aus faktor viia enthalten und deren verwendung
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
WO1993009804A1 (fr) * 1991-11-18 1993-05-27 The Scripps Research Institute Polypeptides derives de la serine protease et anticorps anti-peptidiques, systemes et procedes therapeutiques empechant la coagulation du sang

Also Published As

Publication number Publication date
DE69413817D1 (de) 1998-11-12
FI956055A7 (fi) 1996-01-26
CN1125450A (zh) 1996-06-26
NZ267453A (en) 1997-03-24
JPH08511794A (ja) 1996-12-10
CA2164422A1 (fr) 1995-01-05
CZ334095A3 (en) 1996-07-17
WO1995000541A1 (fr) 1995-01-05
US5962418A (en) 1999-10-05
ATE171950T1 (de) 1998-10-15
DE69413817T2 (de) 1999-06-10
HUT74873A (en) 1997-02-28
DK0703923T3 (da) 1999-06-21
AU691814B2 (en) 1998-05-28
FI956055L (fi) 1996-01-26
HU9503593D0 (en) 1996-02-28
FI956055A0 (fi) 1995-12-15
AU6975594A (en) 1995-01-17
EP0703923A1 (fr) 1996-04-03
EP0703923B1 (fr) 1998-10-07
NO955067D0 (no) 1995-12-14
NO955067L (no) 1995-12-14

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