[go: up one dir, main page]

NO955067L - FVII/TF peptider - Google Patents

FVII/TF peptider

Info

Publication number
NO955067L
NO955067L NO955067A NO955067A NO955067L NO 955067 L NO955067 L NO 955067L NO 955067 A NO955067 A NO 955067A NO 955067 A NO955067 A NO 955067A NO 955067 L NO955067 L NO 955067L
Authority
NO
Norway
Prior art keywords
fvii
peptides
fragments
rchegyslladgvsct
fclpafegrnce
Prior art date
Application number
NO955067A
Other languages
English (en)
Other versions
NO955067D0 (no
Inventor
Ross W Stephens
Lars Orning
Kjell Steinar Sakariassen
Original Assignee
Nycomed Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939312601A external-priority patent/GB9312601D0/en
Application filed by Nycomed Pharma As filed Critical Nycomed Pharma As
Publication of NO955067L publication Critical patent/NO955067L/no
Publication of NO955067D0 publication Critical patent/NO955067D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Den foreliggende oppfinnelsen angår til forbindelser som omfatter aminosyresekvenser med formel GA): -CVNENGGCEQYCSD-, (IB): -FCLPAFEGRNCE- og/eller (IC): - ! RCHEGYSLLADGVSCT- som også omfatter peptidfragmenter, etere, amider, salter, sykliske l derivater, funksjonelle analoger og utvidede peptidkjeder med aminosyrer eller peptider ved ; terminalene til sekvensene eller fragmentene nevnt over, for bruk til forhindring eller inhibering av binding av vevsfaktor til FVII.
NO955067A 1993-06-18 1995-12-14 FVII/TF peptider NO955067D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939312601A GB9312601D0 (en) 1993-06-18 1993-06-18 Peptides
GB9409335A GB9409335D0 (en) 1993-06-18 1994-05-10 Peptides
PCT/GB1994/001315 WO1995000541A1 (en) 1993-06-18 1994-06-17 Factor vii-derived peptides

Publications (2)

Publication Number Publication Date
NO955067L true NO955067L (no) 1995-12-14
NO955067D0 NO955067D0 (no) 1995-12-14

Family

ID=26303086

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955067A NO955067D0 (no) 1993-06-18 1995-12-14 FVII/TF peptider

Country Status (15)

Country Link
US (1) US5962418A (no)
EP (1) EP0703923B1 (no)
JP (1) JPH08511794A (no)
CN (1) CN1125450A (no)
AT (1) ATE171950T1 (no)
CA (1) CA2164422A1 (no)
CZ (1) CZ334095A3 (no)
DE (1) DE69413817T2 (no)
DK (1) DK0703923T3 (no)
FI (1) FI956055A7 (no)
HU (1) HUT74873A (no)
NO (1) NO955067D0 (no)
NZ (1) NZ267453A (no)
SK (1) SK156395A3 (no)
WO (1) WO1995000541A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
GB9425381D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
GB9425380D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
WO1999013062A1 (en) * 1997-09-09 1999-03-18 Nycomed Imaging As Factors vii fragments and analogs thereof and their use in the treatment of blood clotting disorders
WO1999013063A1 (en) * 1997-09-09 1999-03-18 Nycomed Imaging As Factor vii fragments and analogs thereof and their use in the treatment of blood clottng disorders
EP0987274A1 (en) 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Factor VIIa Inhibitors
JP2003530819A (ja) 1999-06-14 2003-10-21 ノボ ノルディスク アクティーゼルスカブ ＦＶＩＩａ／ＴＦ活性阻害化合物
EP1196432A2 (en) 1999-07-02 2002-04-17 Genentech, Inc. FVIIa ANTAGONISTS
US7164002B2 (en) 2002-02-06 2007-01-16 Genentech, Inc. FVIIa antagonists
US20060257359A1 (en) * 2005-02-28 2006-11-16 Cedric Francois Modifying macrophage phenotype for treatment of disease
CA3010310C (en) 2016-01-15 2022-11-22 Rigshospitalet A positron-emitting 18-f labelled factor viia (fviia) imaging agent and method of use thereof
WO2018091058A1 (en) 2016-11-17 2018-05-24 Rigshospitalet 177-lu labeled active site inhibited factor vii

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496927A (en) * 1985-02-04 1996-03-05 Merrell Pharmaceuticals Inc. Peptidase inhibitors
CA1298033C (en) * 1985-04-16 1992-03-24 Takaharu Tanaka Dipeptide derivative of fatty acid
US5087564A (en) * 1985-06-20 1992-02-11 Monsanto Company Release of recombinant peptides from polypeptides using V8 endopeptidase
US5047401A (en) * 1985-09-09 1991-09-10 Board Of Regents, The University Of Texas System Use of dipeptide alkyl esters to treat GVHD
EP0391999A4 (en) * 1988-09-23 1991-03-13 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
JP3330932B2 (ja) * 1990-01-29 2002-10-07 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 抗凝固剤タンパク質
DE4007902A1 (de) * 1990-03-13 1991-09-19 Behringwerke Ag Synthetische peptide, die sequenzen aus faktor viia enthalten und deren verwendung
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
WO1993009804A1 (en) * 1991-11-18 1993-05-27 The Scripps Research Institute Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation

Also Published As

Publication number Publication date
HUT74873A (en) 1997-02-28
DE69413817D1 (de) 1998-11-12
WO1995000541A1 (en) 1995-01-05
FI956055L (fi) 1996-01-26
ATE171950T1 (de) 1998-10-15
AU691814B2 (en) 1998-05-28
NO955067D0 (no) 1995-12-14
JPH08511794A (ja) 1996-12-10
CZ334095A3 (en) 1996-07-17
CN1125450A (zh) 1996-06-26
DE69413817T2 (de) 1999-06-10
EP0703923B1 (en) 1998-10-07
US5962418A (en) 1999-10-05
CA2164422A1 (en) 1995-01-05
HU9503593D0 (en) 1996-02-28
AU6975594A (en) 1995-01-17
FI956055A0 (fi) 1995-12-15
DK0703923T3 (da) 1999-06-21
FI956055A7 (fi) 1996-01-26
EP0703923A1 (en) 1996-04-03
NZ267453A (en) 1997-03-24
SK156395A3 (en) 1996-06-05

Similar Documents

Publication Publication Date Title
EA200000652A1 (ru) Кристаллы глюкагоноподобного пептида 1
NO955067L (no) FVII/TF peptider
DK0469074T3 (da) Cystein-tilsatte varianter af IL-3 og kemiske modifikationer deraf
MY135057A (en) Dolastatin 15 derivatives
AP2000001888A0 (en) Method for treatment of diabetes using peptides analogues of insulin.
ATE408623T1 (de) Wiederherstellung nach nervenschädigung
FI20075338A7 (fi) gp350/220:n ei silmukoivia muutoksia
NO20020176L (no) Sykliske peptidderivater som inhibitorer for intergrin <alfa>v<beta>6
NZ336793A (en) Method for stabilizing peptides by adding an organic acid and then lyophilizing the peptide mixture
EA200300678A1 (ru) Пептиды и/или белки, а также их применение для получения терапевтической и/или профилактической фармацевтической композиции
DE69029377D1 (de) Substituierungsanaloge von magaininpeptiden
HU896606D0 (en) Process for the preparation of aminoacid derivatives inhibiting enzymes and pharmaceutical compositions thereof
SE9503679D0 (sv) Antioxidants
DE602004023827D1 (de) Ionenkanalaktivität hemmende niedrigmolekulare peptide
NZ290050A (en) Treatment of anxiety with gabapentin
GB9225021D0 (en) Organic compounds
DE3571990D1 (en) Reduced peptides, inhibitors of gastric secretion, preparation process and pharmaceutical compositions containing them
Miller et al. Amino acid sequences around the cysteine residues of rabbit muscle triose phosphate isomerase
DK0717048T3 (da) Cyclohexapeptider og deres blandinger, fremgangsmåde til fremstilling deraf samt deres anvendelse
DE3162674D1 (en) A purified polypeptide, a process for its preparation, its use and pharmaceutical compositions containing it
ATE178909T1 (de) Inhibitor peptid spezifisch für cathepsin-l
ATE348840T1 (de) Verfahren zur prävention einer durch gefrieren induzierten abnahme der aktivität eines proteins
ES2012530A6 (es) Metodo de produccion de un edulcorante proteinico.
EP0165492A3 (en) Process for manufacturing preparations promoting wound healing, and such preparations
GR3015492T3 (en) ZNS-active hexapeptides with antiamnestic activity.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application