SK12542002A3 - Riadený systém prísunu liečiva na orálne podávanie ciprofloxacínu raz denne - Google Patents
Riadený systém prísunu liečiva na orálne podávanie ciprofloxacínu raz denne Download PDFInfo
- Publication number
- SK12542002A3 SK12542002A3 SK1254-2002A SK12542002A SK12542002A3 SK 12542002 A3 SK12542002 A3 SK 12542002A3 SK 12542002 A SK12542002 A SK 12542002A SK 12542002 A3 SK12542002 A3 SK 12542002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ciprofloxacin
- weight
- formulation
- agent
- xanthan gum
- Prior art date
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- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940031304 ciprofloxacin 1000 mg Drugs 0.000 description 1
- 229960004106 citric acid Drugs 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 238000013267 controlled drug release Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 description 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 235000020937 fasting conditions Nutrition 0.000 description 1
- 229940085942 formulation r Drugs 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002449 glycine Drugs 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 239000011346 highly viscous material Substances 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- 230000002706 hydrostatic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 235000010494 karaya gum Nutrition 0.000 description 1
- 239000000231 karaya gum Substances 0.000 description 1
- 229940039371 karaya gum Drugs 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000008063 pharmaceutical solvent Substances 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 235000020004 porter Nutrition 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 229920003124 powdered cellulose Polymers 0.000 description 1
- 235000019814 powdered cellulose Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 229940043230 sarcosine Drugs 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 description 1
- 235000010378 sodium ascorbate Nutrition 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229960002668 sodium chloride Drugs 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 210000005070 sphincter Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000003799 water insoluble solvent Substances 0.000 description 1
- 239000003021 water soluble solvent Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51788700A | 2000-03-03 | 2000-03-03 | |
| PCT/IB2001/000279 WO2001064183A1 (en) | 2000-03-03 | 2001-02-28 | Orally administered controlled delivery system for once daily administration of ciprofloxacin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK12542002A3 true SK12542002A3 (sk) | 2003-05-02 |
Family
ID=24061635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1254-2002A SK12542002A3 (sk) | 2000-03-03 | 2001-02-28 | Riadený systém prísunu liečiva na orálne podávanie ciprofloxacínu raz denne |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP1263409A1 (es) |
| JP (1) | JP2003525229A (es) |
| KR (1) | KR20030009374A (es) |
| CN (1) | CN1420763A (es) |
| AP (2) | AP2001002084A0 (es) |
| AR (1) | AR032614A1 (es) |
| AU (1) | AU3589701A (es) |
| BG (1) | BG107055A (es) |
| BR (1) | BR0108958A (es) |
| CA (1) | CA2400950A1 (es) |
| CZ (1) | CZ20022883A3 (es) |
| DO (1) | DOP2001000130A (es) |
| EA (1) | EA200200914A1 (es) |
| EC (1) | ECSP013952A (es) |
| EE (1) | EE200200497A (es) |
| GT (1) | GT200100033A (es) |
| HN (1) | HN2001000038A (es) |
| HR (1) | HRP20020715A2 (es) |
| HU (1) | HUP0204417A3 (es) |
| IL (1) | IL151553A0 (es) |
| IS (1) | IS6532A (es) |
| MX (1) | MXPA02008568A (es) |
| NO (1) | NO20024108L (es) |
| NZ (1) | NZ520927A (es) |
| OA (1) | OA12381A (es) |
| PE (1) | PE20011113A1 (es) |
| PL (1) | PL365071A1 (es) |
| SK (1) | SK12542002A3 (es) |
| WO (1) | WO2001064183A1 (es) |
| YU (1) | YU66202A (es) |
| ZA (1) | ZA200206764B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0209265D0 (en) | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| US20030229101A1 (en) * | 2002-06-06 | 2003-12-11 | Sherman Bernard Charles | Tablets comprising ciprofloxacin hydrochloride |
| DE10351448A1 (de) | 2003-11-04 | 2005-06-09 | Bayer Healthcare Ag | Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften |
| DE602005007205D1 (de) | 2005-07-19 | 2008-07-10 | Ethypharm Sa | Gastroretentive Zusammensetzungen und Verfahren zur Herstellung |
| DE602006012962D1 (de) * | 2006-07-19 | 2010-04-29 | Tabuk Pharmaceutical Mfg Co | Pharmazeutische Zubereitungen von Ciprofloxacin |
| EP3247384B1 (en) | 2015-01-14 | 2023-10-04 | The Regents of the University of Colorado, a body corporate | In vitro method of diagnosis of type 1 diabetes with insulin mimotopes |
| US20190070299A1 (en) * | 2016-02-23 | 2019-03-07 | Matripharm International Inc. | Dual-rate release formulation with high drug loading |
| AU2017236977B2 (en) | 2016-03-24 | 2022-05-26 | Immunomolecular Therapeutics, Inc. | Methods of treating autoimmune disease |
| US11052060B2 (en) | 2018-02-12 | 2021-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Compounds and methods for treating autoimmunity |
| US11013707B2 (en) | 2018-03-23 | 2021-05-25 | The Regents Of The University Of Colorado, A Body Corporate | Administration of oral methyldopa |
| CN109806237A (zh) * | 2019-03-13 | 2019-05-28 | 悦康药业集团上海制药有限公司 | 一种乳酸环丙沙星泡腾片及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096714A (en) * | 1988-06-28 | 1992-03-17 | Hauser-Kuhrts, Inc. | Prolonged release drug tablet formulations |
| JPH0624959A (ja) * | 1991-10-04 | 1994-02-01 | Bayer Yakuhin Kk | 胃内浮遊型薬物徐放性固形製剤 |
| DE4406424A1 (de) * | 1994-02-28 | 1995-08-31 | Bayer Ag | Expandierbare Arzneiformen |
| DE19839057A1 (de) * | 1998-08-28 | 2000-03-02 | Koch Berthold | Spülluft-Regler für eine Trockenvorrichtung für Druckluft |
| ID29843A (id) * | 1998-09-14 | 2001-10-18 | Ranbaxy Lab Ltd | Sistem pemberian obat melalui mulut yang dikontrol secara teratur yang memberikan pengontrolan tempat dan bersifat sementara |
-
2001
- 2001-02-28 EA EA200200914A patent/EA200200914A1/ru unknown
- 2001-02-28 JP JP2001563081A patent/JP2003525229A/ja not_active Withdrawn
- 2001-02-28 PL PL01365071A patent/PL365071A1/xx not_active Application Discontinuation
- 2001-02-28 BR BR0108958-7A patent/BR0108958A/pt not_active IP Right Cessation
- 2001-02-28 EE EEP200200497A patent/EE200200497A/xx unknown
- 2001-02-28 NZ NZ520927A patent/NZ520927A/xx unknown
- 2001-02-28 YU YU66202A patent/YU66202A/sh unknown
- 2001-02-28 AP APAP/P/2001/002084A patent/AP2001002084A0/en unknown
- 2001-02-28 AP APAP/P/2002/002627A patent/AP1485A/en active
- 2001-02-28 MX MXPA02008568A patent/MXPA02008568A/es unknown
- 2001-02-28 CZ CZ20022883A patent/CZ20022883A3/cs unknown
- 2001-02-28 HU HU0204417A patent/HUP0204417A3/hu unknown
- 2001-02-28 SK SK1254-2002A patent/SK12542002A3/sk unknown
- 2001-02-28 WO PCT/IB2001/000279 patent/WO2001064183A1/en not_active Ceased
- 2001-02-28 HR HRP20020715 patent/HRP20020715A2/hr not_active Application Discontinuation
- 2001-02-28 OA OA1200200267A patent/OA12381A/en unknown
- 2001-02-28 KR KR1020027011441A patent/KR20030009374A/ko not_active Ceased
- 2001-02-28 AR ARP010100957A patent/AR032614A1/es not_active Application Discontinuation
- 2001-02-28 EP EP01908038A patent/EP1263409A1/en not_active Withdrawn
- 2001-02-28 IL IL15155301A patent/IL151553A0/xx unknown
- 2001-02-28 CA CA002400950A patent/CA2400950A1/en not_active Abandoned
- 2001-02-28 CN CN01805998A patent/CN1420763A/zh active Pending
- 2001-02-28 AU AU35897/01A patent/AU3589701A/en not_active Abandoned
- 2001-03-01 PE PE2001000206A patent/PE20011113A1/es not_active Application Discontinuation
- 2001-03-01 EC EC2001003952A patent/ECSP013952A/es unknown
- 2001-03-01 GT GT200100033A patent/GT200100033A/es unknown
- 2001-03-02 DO DO2001000130A patent/DOP2001000130A/es unknown
- 2001-03-02 HN HN2001000038A patent/HN2001000038A/es unknown
-
2002
- 2002-08-23 ZA ZA200206764A patent/ZA200206764B/en unknown
- 2002-08-28 NO NO20024108A patent/NO20024108L/no unknown
- 2002-08-28 IS IS6532A patent/IS6532A/is unknown
- 2002-09-02 BG BG107055A patent/BG107055A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2400950A1 (en) | 2001-09-07 |
| PE20011113A1 (es) | 2001-10-14 |
| WO2001064183A1 (en) | 2001-09-07 |
| ZA200206764B (en) | 2003-03-04 |
| CZ20022883A3 (cs) | 2003-04-16 |
| NZ520927A (en) | 2003-06-30 |
| OA12381A (en) | 2004-09-06 |
| IL151553A0 (en) | 2003-04-10 |
| CN1420763A (zh) | 2003-05-28 |
| NO20024108D0 (no) | 2002-08-28 |
| YU66202A (sh) | 2005-09-19 |
| EA200200914A1 (ru) | 2003-02-27 |
| AU3589701A (en) | 2001-09-12 |
| JP2003525229A (ja) | 2003-08-26 |
| AP2002002627A0 (en) | 2002-09-30 |
| HRP20020715A2 (en) | 2004-12-31 |
| PL365071A1 (en) | 2004-12-27 |
| IS6532A (is) | 2002-08-28 |
| EP1263409A1 (en) | 2002-12-11 |
| HN2001000038A (es) | 2005-03-23 |
| BG107055A (bg) | 2003-06-30 |
| AR032614A1 (es) | 2003-11-19 |
| AP1485A (en) | 2005-10-31 |
| DOP2001000130A (es) | 2004-03-31 |
| HUP0204417A3 (en) | 2005-03-29 |
| ECSP013952A (es) | 2002-04-23 |
| KR20030009374A (ko) | 2003-01-29 |
| AP2001002084A0 (en) | 2001-03-31 |
| GT200100033A (es) | 2001-10-25 |
| HUP0204417A2 (en) | 2003-05-28 |
| EE200200497A (et) | 2004-02-16 |
| NO20024108L (no) | 2002-10-25 |
| MXPA02008568A (es) | 2003-02-24 |
| BR0108958A (pt) | 2003-09-30 |
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