SK1012004A3 - Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka - Google Patents

Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka Download PDF

Info

Publication number: SK1012004A3
Authority: SK; Slovakia
Prior art keywords: azithromycin; dose; medicament; treatment; range
Prior art date: 2001-08-21

Application number

SK101-2004A

Other languages

English (en)

Slovak (sk)

Inventor

Michael William Dunne

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-21

Filing date

2002-07-31

Publication date

2005-04-01

2002-07-31 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2005-04-01 Publication of SK1012004A3 publication Critical patent/SK1012004A3/sk

Links

229960004099 azithromycin Drugs 0.000 title claims abstract description 46
MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 title claims abstract description 46
206010057190 Respiratory tract infections Diseases 0.000 title claims abstract description 17
239000003814 drug Substances 0.000 title claims description 15
238000004519 manufacturing process Methods 0.000 title claims description 8
230000037396 body weight Effects 0.000 claims description 13
208000022760 infectious otitis media Diseases 0.000 claims description 10
239000007788 liquid Substances 0.000 claims description 5
108090000623 proteins and genes Proteins 0.000 claims description 4
238000000034 method Methods 0.000 abstract description 8
208000015181 infectious disease Diseases 0.000 description 16
244000052769 pathogen Species 0.000 description 10
241000606768 Haemophilus influenzae Species 0.000 description 8
208000005141 Otitis Diseases 0.000 description 6
208000019258 ear infection Diseases 0.000 description 6
230000001154 acute effect Effects 0.000 description 5
230000001717 pathogenic effect Effects 0.000 description 5
241000699694 Gerbillinae Species 0.000 description 4
241000588655 Moraxella catarrhalis Species 0.000 description 4
238000011156 evaluation Methods 0.000 description 4
206010033078 Otitis media Diseases 0.000 description 3
230000003115 biocidal effect Effects 0.000 description 3
239000002775 capsule Substances 0.000 description 3
239000002552 dosage form Substances 0.000 description 3
230000000813 microbial effect Effects 0.000 description 3
238000012360 testing method Methods 0.000 description 3
238000002560 therapeutic procedure Methods 0.000 description 3
241000194032 Enterococcus faecalis Species 0.000 description 2
241001465754 Metazoa Species 0.000 description 2
241000193996 Streptococcus pyogenes Species 0.000 description 2
238000011161 development Methods 0.000 description 2
210000000959 ear middle Anatomy 0.000 description 2
230000000694 effects Effects 0.000 description 2
230000008029 eradication Effects 0.000 description 2
230000001404 mediated effect Effects 0.000 description 2
238000010172 mouse model Methods 0.000 description 2
210000003454 tympanic membrane Anatomy 0.000 description 2
VQEMDSRIOVZAOM-UHFFFAOYSA-N 4-(4-methylsulfonylphenyl)-1,3-thiazol-2-amine Chemical compound C1=CC(S(=O)(=O)C)=CC=C1C1=CSC(N)=N1 VQEMDSRIOVZAOM-UHFFFAOYSA-N 0.000 description 1
101150076489 B gene Proteins 0.000 description 1
206010008326 Cervicitis gonococcal Diseases 0.000 description 1
241000606153 Chlamydia trachomatis Species 0.000 description 1
208000035473 Communicable disease Diseases 0.000 description 1
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 1
229930006677 Erythromycin A Natural products 0.000 description 1
241000282412 Homo Species 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
206010040007 Sense of oppression Diseases 0.000 description 1
201000010439 acute gonococcal cervicitis Diseases 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
229960004924 azithromycin dihydrate Drugs 0.000 description 1
230000001332 colony forming effect Effects 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
230000037213 diet Effects 0.000 description 1
235000005911 diet Nutrition 0.000 description 1
230000008034 disappearance Effects 0.000 description 1
208000032625 disorder of ear Diseases 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000012377 drug delivery Methods 0.000 description 1
229960003276 erythromycin Drugs 0.000 description 1
239000012530 fluid Substances 0.000 description 1
230000037406 food intake Effects 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
208000028320 gonococcal cervicitis Diseases 0.000 description 1
239000012729 immediate-release (IR) formulation Substances 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
230000002458 infectious effect Effects 0.000 description 1
210000004969 inflammatory cell Anatomy 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
238000001990 intravenous administration Methods 0.000 description 1
238000009533 lab test Methods 0.000 description 1
239000006194 liquid suspension Substances 0.000 description 1
230000007774 longterm Effects 0.000 description 1
210000004072 lung Anatomy 0.000 description 1
239000003120 macrolide antibiotic agent Substances 0.000 description 1
206010027175 memory impairment Diseases 0.000 description 1
150000004682 monohydrates Chemical class 0.000 description 1
230000002085 persistent effect Effects 0.000 description 1
208000023504 respiratory system disease Diseases 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000011125 single therapy Methods 0.000 description 1
239000013589 supplement Substances 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
230000009747 swallowing Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
239000003826 tablet Substances 0.000 description 1
208000000143 urethritis Diseases 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

SK101-2004A 2001-08-21 2002-07-31 Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka SK1012004A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US31386701P	2001-08-21	2001-08-21
PCT/IB2002/003076 WO2003018031A2 (fr)	2001-08-21	2002-07-31	Azithromycine unidose

Publications (1)

Publication Number	Publication Date
SK1012004A3 true SK1012004A3 (sk)	2005-04-01

Family

ID=23217490

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK101-2004A SK1012004A3 (sk)	2001-08-21	2002-07-31	Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka

Country Status (25)

Country	Link
US (3)	US20030148964A1 (fr)
EP (1)	EP1418924A2 (fr)
JP (1)	JP2005501862A (fr)
KR (1)	KR20040032942A (fr)
AP (1)	AP1729A (fr)
BG (1)	BG108537A (fr)
BR (1)	BR0211830A (fr)
CA (1)	CA2458135A1 (fr)
CZ (1)	CZ2004232A3 (fr)
EA (1)	EA200400214A1 (fr)
EC (1)	ECSP044985A (fr)
GE (1)	GEP20063812B (fr)
HR (1)	HRP20040163A2 (fr)
HU (1)	HUP0401332A2 (fr)
IL (1)	IL159585A0 (fr)
IS (1)	IS7092A (fr)
MA (1)	MA27059A1 (fr)
MX (1)	MXPA04001605A (fr)
OA (1)	OA12845A (fr)
PL (1)	PL367888A1 (fr)
SK (1)	SK1012004A3 (fr)
TN (1)	TNSN04035A1 (fr)
WO (1)	WO2003018031A2 (fr)
YU (1)	YU8804A (fr)
ZA (1)	ZA200400804B (fr)

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WO2005009447A1 (fr) *	2003-07-24	2005-02-03	Pliva - Research And Development Ltd.	Dose unique a dissolution rapide d'azithromycine
JP2007513139A (ja)	2003-12-04	2007-05-24	ファイザー・プロダクツ・インク	安定性の改善した多粒子組成物
PL1691787T3 (pl)	2003-12-04	2008-11-28	Pfizer Prod Inc	Sposób wytwarzania farmaceutycznych systemów wielocząstkowych
BRPI0417348A (pt)	2003-12-04	2007-03-13	Pfizer Prod Inc	processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
US6984403B2 (en)	2003-12-04	2006-01-10	Pfizer Inc.	Azithromycin dosage forms with reduced side effects
US7468428B2 (en)	2004-03-17	2008-12-23	App Pharmaceuticals, Llc	Lyophilized azithromycin formulation
US20060116336A1 (en) *	2004-03-17	2006-06-01	American Pharmaceutical Partners, Inc.	Lyophilized azithromycin formulation
ES2594368T3 (es)	2005-12-08	2016-12-19	Insmed Incorporated	Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares
US9119783B2 (en)	2007-05-07	2015-09-01	Insmed Incorporated	Method of treating pulmonary disorders with liposomal amikacin formulations
US20090005326A1 (en) *	2007-06-26	2009-01-01	Idexx Laboratories, Inc.	Single dose roxithromycin
US20090197956A1 (en) *	2008-02-04	2009-08-06	Arbor Pharmaceuticals, Inc.	Treatment of acute otitis media with xylitol and n-acetylcysteine
WO2009114810A2 (fr) *	2008-03-14	2009-09-17	The Florida International Uinversity Board Of Trustees	Utilisation d'ellagitannines comme inhibiteurs de la détection du quorum bactérien
US20130156803A1 (en)	2011-06-04	2013-06-20	Rochester General Hospital Research Institute	Compositions and methods related to p6
AU2013352259B2 (en)	2012-11-29	2018-06-14	Insmed Incorporated	Stabilized vancomycin formulations
KR102657132B1 (ko)	2014-05-15	2024-04-12	인스메드 인코포레이티드	폐의 비-결핵성 마이코박테리아 감염을 치료하기 위한 방법
JP7460534B2 (ja)	2018-03-30	2024-04-02	インスメッドインコーポレイテッド	リポソーム医薬品の連続製造方法
WO2021163451A1 (fr) *	2020-02-14	2021-08-19	Asklepios Biopharmaceutical, Inc.	Procédé de traitement d'une toxicité associée à une thérapie génique avec des antibiotiques

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US53264A (en) *		1866-03-20		Improved ditching-machine
YU43116B (en) *	1979-04-02	1989-04-30	Pliva Pharm & Chem Works	Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
YU43006B (en) *	1981-03-06	1989-02-28	Pliva Pharm & Chem Works	Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) *	1982-07-19	1984-10-02	Pfizer Inc.	N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
UA27040C2 (uk) *	1987-07-09	2000-02-28	Пфайзер Інк.	Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу
WO1989002271A1 (fr) *	1987-09-10	1989-03-23	Pfizer	Azithromycine et derives utilises comme agents anti-protozoaires
YU45590A (sh) *	1990-03-07	1992-07-20	PLIVA FARMACEVTSKA, KEMIJSKA, PREHRAMBENA I KOZMETIČKA INDUSTRIJA s.p.o.	Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
TW271400B (fr) *	1992-07-30	1996-03-01	Pfizer
JP2696608B2 (ja) *	1993-05-19	1998-01-14	ファイザー・インク．	アジスロマイシンの中間物質
US5605889A (en) *	1994-04-29	1997-02-25	Pfizer Inc.	Method of administering azithromycin
SI9520049A (en) *	1994-05-06	1997-12-31	Pfizer	Controlled-release dosage forms of azithromycin
HRP980189B1 (en) *	1998-04-06	2004-04-30	Pliva Pharm & Chem Works	Novel 15-membered lactams ketolides
US6239113B1 (en) *	1999-03-31	2001-05-29	Insite Vision, Incorporated	Topical treatment or prevention of ocular infections
US20040053264A1 (en) *	2002-02-01	2004-03-18	Park Sung Sup	Clinical panel assay using DNA chips

2002
- 2002-07-31 BR BR0211830-0A patent/BR0211830A/pt not_active IP Right Cessation
- 2002-07-31 CZ CZ2004232A patent/CZ2004232A3/cs unknown
- 2002-07-31 YU YU8804A patent/YU8804A/sh unknown
- 2002-07-31 KR KR10-2004-7002492A patent/KR20040032942A/ko not_active Ceased
- 2002-07-31 SK SK101-2004A patent/SK1012004A3/sk not_active Application Discontinuation
- 2002-07-31 OA OA1200400048A patent/OA12845A/en unknown
- 2002-07-31 AP APAP/P/2004/002968A patent/AP1729A/en active
- 2002-07-31 MX MXPA04001605A patent/MXPA04001605A/es active IP Right Grant
- 2002-07-31 HU HU0401332A patent/HUP0401332A2/hu unknown
- 2002-07-31 GE GE5411A patent/GEP20063812B/en unknown
- 2002-07-31 EP EP02753170A patent/EP1418924A2/fr not_active Withdrawn
- 2002-07-31 PL PL02367888A patent/PL367888A1/xx not_active Application Discontinuation
- 2002-07-31 IL IL15958502A patent/IL159585A0/xx unknown
- 2002-07-31 HR HR20040163A patent/HRP20040163A2/xx not_active Application Discontinuation
- 2002-07-31 EA EA200400214A patent/EA200400214A1/ru unknown
- 2002-07-31 JP JP2003522549A patent/JP2005501862A/ja active Pending
- 2002-07-31 WO PCT/IB2002/003076 patent/WO2003018031A2/fr not_active Ceased
- 2002-07-31 CA CA002458135A patent/CA2458135A1/fr not_active Abandoned
- 2002-08-21 US US10/224,903 patent/US20030148964A1/en not_active Abandoned
2003
- 2003-07-25 US US10/628,102 patent/US6987093B2/en not_active Expired - Fee Related
- 2003-12-23 IS IS7092A patent/IS7092A/is unknown
2004
- 2004-01-21 BG BG108537A patent/BG108537A/bg unknown
- 2004-01-30 ZA ZA200400804A patent/ZA200400804B/en unknown
- 2004-02-11 MA MA27523A patent/MA27059A1/fr unknown
- 2004-02-20 EC EC2004004985A patent/ECSP044985A/es unknown
- 2004-02-20 TN TNP2004000035A patent/TNSN04035A1/fr unknown
2005
- 2005-06-29 US US11/172,012 patent/US7067493B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2005501862A (ja)	2005-01-20
HRP20040163A2 (en)	2005-02-28
US20030148964A1 (en)	2003-08-07
US20050250712A1 (en)	2005-11-10
EP1418924A2 (fr)	2004-05-19
US7067493B2 (en)	2006-06-27
AP1729A (en)	2007-03-26
MXPA04001605A (es)	2004-07-08
IL159585A0 (en)	2004-06-01
IS7092A (is)	2003-12-23
MA27059A1 (fr)	2004-12-20
BG108537A (bg)	2005-02-28
CA2458135A1 (fr)	2003-03-06
CZ2004232A3 (cs)	2005-10-12
AP2004002968A0 (en)	2004-03-31
EA200400214A1 (ru)	2004-06-24
US6987093B2 (en)	2006-01-17
OA12845A (en)	2006-09-15
WO2003018031A3 (fr)	2003-10-02
KR20040032942A (ko)	2004-04-17
ECSP044985A (es)	2004-04-28
GEP20063812B (en)	2006-05-10
TNSN04035A1 (fr)	2006-06-01
BR0211830A (pt)	2004-09-08
PL367888A1 (en)	2005-03-07
US20040023898A1 (en)	2004-02-05
WO2003018031A2 (fr)	2003-03-06
ZA200400804B (en)	2005-05-03
HUP0401332A2 (hu)	2004-11-29
YU8804A (sh)	2006-08-17

Publication	Publication Date	Title
SK1012004A3 (sk)	2005-04-01	Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka
Biondi et al.	1997	Psychological stress, neuroimmunomodulation, and susceptibility to infectious diseases in animals and man: a review
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US20060057133A1 (en)	2006-03-16	Topical pathogenic-tissue-destroying liquid
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Bhatt et al.	2002	Anthrax revisited
Selliah et al.	2004	Pharmacokinetics of cationic liposome-encapsulated doxycycline in mice challenged with genital infection by Chlamydia trachomatis

Legal Events

Date	Code	Title	Description
2010-11-08	FC9A	Refused patent application