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SI4320112T1 - Oksoizoindolin spojine, substituirane s piridinilom - Google Patents

Oksoizoindolin spojine, substituirane s piridinilom

Info

Publication number
SI4320112T1
SI4320112T1 SI202230144T SI202230144T SI4320112T1 SI 4320112 T1 SI4320112 T1 SI 4320112T1 SI 202230144 T SI202230144 T SI 202230144T SI 202230144 T SI202230144 T SI 202230144T SI 4320112 T1 SI4320112 T1 SI 4320112T1
Authority
SI
Slovenia
Prior art keywords
oxoisoindoline
compounds
pyridinyl substituted
pyridinyl
substituted
Prior art date
Application number
SI202230144T
Other languages
English (en)
Inventor
Yan Chen
Godwin Kwame Kumi
Audris Huang
Satheesh Kesavan Nair
Bharat Dinkar Shimpukade
Suresh Babu Vishwa Krishna Penmetsa
James Aaron Balog
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of SI4320112T1 publication Critical patent/SI4320112T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
SI202230144T 2021-04-06 2022-04-05 Oksoizoindolin spojine, substituirane s piridinilom SI4320112T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN202111016193 2021-04-06
IN202111022098 2021-05-17
EP22718513.9A EP4320112B1 (en) 2021-04-06 2022-04-05 Pyridinyl substituted oxoisoindoline compounds
PCT/US2022/023387 WO2022216644A1 (en) 2021-04-06 2022-04-05 Pyridinyl substituted oxoisoindoline compounds

Publications (1)

Publication Number Publication Date
SI4320112T1 true SI4320112T1 (sl) 2025-09-30

Family

ID=81385129

Family Applications (1)

Application Number Title Priority Date Filing Date
SI202230144T SI4320112T1 (sl) 2021-04-06 2022-04-05 Oksoizoindolin spojine, substituirane s piridinilom

Country Status (26)

Country Link
US (3) US11718601B2 (sl)
EP (1) EP4320112B1 (sl)
JP (1) JP2024515243A (sl)
KR (1) KR20230165815A (sl)
AR (1) AR125298A1 (sl)
AU (1) AU2022253242A1 (sl)
BR (1) BR112023020077A2 (sl)
CA (1) CA3214244A1 (sl)
CL (1) CL2023002966A1 (sl)
CO (1) CO2023013321A2 (sl)
DK (1) DK4320112T3 (sl)
ES (1) ES3035755T3 (sl)
FI (1) FI4320112T3 (sl)
HR (1) HRP20250796T1 (sl)
HU (1) HUE072309T2 (sl)
IL (1) IL307343A (sl)
LT (1) LT4320112T (sl)
MX (1) MX2023011715A (sl)
PE (1) PE20231941A1 (sl)
PL (1) PL4320112T3 (sl)
PT (1) PT4320112T (sl)
RS (1) RS66982B1 (sl)
SI (1) SI4320112T1 (sl)
SM (1) SMT202500281T1 (sl)
TW (1) TWI867287B (sl)
WO (1) WO2022216644A1 (sl)

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TW202346277A (zh) 2022-03-17 2023-12-01 美商基利科學股份有限公司 Ikaros鋅指家族降解劑及其用途
CN120677149A (zh) * 2023-02-08 2025-09-19 细胞基因公司 用于选择性降解工程化蛋白的化合物和组合物
AR133696A1 (es) 2023-09-02 2025-10-22 Bristol Myers Squibb Co Compuestos de fenil oxooxazolil piperidinadiona sustituida
WO2025199379A1 (en) 2024-03-22 2025-09-25 Bristol-Myers Squibb Company Novel fak degrader compounds and uses thereof
WO2025226767A1 (en) * 2024-04-24 2025-10-30 Bristol-Myers Squibb Company Substituted 3-(5-(6-aminopyridin-2-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione compounds for use in the treatment of cancer
WO2025234888A1 (en) 2024-05-09 2025-11-13 Captor Therapeutics S.A. Nek7 degraders and methods of use thereof
WO2025234887A1 (en) 2024-05-09 2025-11-13 Captor Therapeutics S.A. Nek7 degraders and methods of use thereof

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Also Published As

Publication number Publication date
LT4320112T (lt) 2025-07-10
US20230303527A1 (en) 2023-09-28
PE20231941A1 (es) 2023-12-05
WO2022216644A1 (en) 2022-10-13
EP4320112A1 (en) 2024-02-14
DK4320112T3 (da) 2025-08-18
JP2024515243A (ja) 2024-04-08
EP4320112B1 (en) 2025-05-14
TW202304881A (zh) 2023-02-01
CA3214244A1 (en) 2022-10-13
PT4320112T (pt) 2025-07-07
RS66982B1 (sr) 2025-07-31
US20220324840A1 (en) 2022-10-13
US11718601B2 (en) 2023-08-08
IL307343A (en) 2023-11-01
CL2023002966A1 (es) 2024-02-23
FI4320112T3 (fi) 2025-07-25
MX2023011715A (es) 2023-10-12
AR125298A1 (es) 2023-07-05
SMT202500281T1 (it) 2025-09-12
HRP20250796T1 (hr) 2025-08-29
HUE072309T2 (hu) 2025-11-28
KR20230165815A (ko) 2023-12-05
PL4320112T3 (pl) 2025-07-21
AU2022253242A1 (en) 2023-11-23
BR112023020077A2 (pt) 2023-11-14
US20240376082A1 (en) 2024-11-14
TWI867287B (zh) 2024-12-21
ES3035755T3 (en) 2025-09-08
CO2023013321A2 (es) 2023-10-19

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