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SI3625368T1 - Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham - Google Patents

Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham

Info

Publication number
SI3625368T1
SI3625368T1 SI201930417T SI201930417T SI3625368T1 SI 3625368 T1 SI3625368 T1 SI 3625368T1 SI 201930417 T SI201930417 T SI 201930417T SI 201930417 T SI201930417 T SI 201930417T SI 3625368 T1 SI3625368 T1 SI 3625368T1
Authority
SI
Slovenia
Prior art keywords
assessing
risk
methods
genetic testing
progressive multifocal
Prior art date
Application number
SI201930417T
Other languages
English (en)
Inventor
Eli Hatchwell
Peggy S. Eis
Edward B. SMITH III
Yassine Taoufik
Original Assignee
Pml Screening, Llc
Universite Paris-Saclay Batiment Breguet
The Assistance Publique-Hopitaux De Paris (Aphp)
The Institut National de la Sante et de la Recherche Medicale (INSERM)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pml Screening, Llc, Universite Paris-Saclay Batiment Breguet, The Assistance Publique-Hopitaux De Paris (Aphp), The Institut National de la Sante et de la Recherche Medicale (INSERM) filed Critical Pml Screening, Llc
Publication of SI3625368T1 publication Critical patent/SI3625368T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI201930417T 2018-08-08 2019-08-08 Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham SI3625368T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862716072P 2018-08-08 2018-08-08
US201862716183P 2018-08-08 2018-08-08
PCT/US2019/045721 WO2020033700A1 (en) 2018-08-08 2019-08-08 Mathods for assessing the risk of developing progressive multifocal leukoencephalopathy caused by john cunningham virus by genetic testing
EP19765344.7A EP3625368B8 (en) 2018-08-08 2019-08-08 Methods for assessing the risk of developing progressive multifocal leukoencephalopathy caused by john cunningham virus by genetic testing

Publications (1)

Publication Number Publication Date
SI3625368T1 true SI3625368T1 (sl) 2023-04-28

Family

ID=67874498

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201930417T SI3625368T1 (sl) 2018-08-08 2019-08-08 Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham
SI201930796T SI4177356T1 (sl) 2018-08-08 2019-08-08 Postopki za ocenjevanje tveganja za razvoj virusne bolezni z genetskim testom

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201930796T SI4177356T1 (sl) 2018-08-08 2019-08-08 Postopki za ocenjevanje tveganja za razvoj virusne bolezni z genetskim testom

Country Status (12)

Country Link
US (6) US10961585B2 (sl)
EP (4) EP3625368B8 (sl)
AU (1) AU2019316556C9 (sl)
CA (1) CA3108807A1 (sl)
DE (1) DE24173683T1 (sl)
DK (2) DK4177356T3 (sl)
ES (2) ES2935891T3 (sl)
FI (2) FI4177356T3 (sl)
HR (2) HRP20221504T1 (sl)
SI (2) SI3625368T1 (sl)
WO (1) WO2020033700A1 (sl)
ZA (2) ZA202100925B (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2951741A2 (en) * 2013-02-03 2015-12-09 Genelex Corporation Systems and methods for quantification and presentation of medical risk arising from unknown factors
US10240205B2 (en) 2017-02-03 2019-03-26 Population Bio, Inc. Methods for assessing risk of developing a viral disease using a genetic test
SI3625368T1 (sl) 2018-08-08 2023-04-28 Pml Screening, Llc Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham
TW202214874A (zh) * 2020-06-08 2022-04-16 印度商裘拉德製藥私人有限公司 用於人類個體中基因分型sting變體之快速方法
AU2021400950A1 (en) * 2020-12-15 2023-07-06 Caris Mpi, Inc. Treatment response signatures
US20240240272A1 (en) * 2021-05-10 2024-07-18 University Of Iowa Research Foundation Targeted massively parallel sequencing for screening of genetic hearing loss and congenital cytomegalovirus-associated hearing loss
CN113143920B (zh) * 2021-05-25 2023-04-25 湖北工业大学 Ponesimod化合物在制备抗EV71病毒药物中的应用
WO2024175586A2 (en) * 2023-02-21 2024-08-29 Vib Vzw Inhibitors of synaptogyrin-3 expression

Family Cites Families (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US696589A (en) 1901-09-30 1902-04-01 Frank I Pleck Bridge-gate.
US1279306A (en) 1918-02-02 1918-09-17 Syndicate Sales Company Butter-merging machine.
US3625214A (en) 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US4906474A (en) 1983-03-22 1990-03-06 Massachusetts Institute Of Technology Bioerodible polyanhydrides for controlled drug delivery
US4557508A (en) 1984-04-12 1985-12-10 Cameron Iron Works, Inc. Tubular connector
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4789734A (en) 1985-08-06 1988-12-06 La Jolla Cancer Research Foundation Vitronectin specific cell receptor derived from mammalian mesenchymal tissue
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
CH671155A5 (sl) 1986-08-18 1989-08-15 Clinical Technologies Ass
US5811128A (en) 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4992445A (en) 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
US5001139A (en) 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
AU4308689A (en) 1988-09-02 1990-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5766573A (en) 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5527681A (en) 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
KR100233781B1 (ko) 1989-11-06 1999-12-01 스테펜 에이. 쉐어윈 동종 재조합을 이용하는 단백질 제조방법
US5252743A (en) 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US5272071A (en) 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE164395T1 (de) 1990-12-03 1998-04-15 Genentech Inc Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
ATE199054T1 (de) 1990-12-06 2001-02-15 Affymetrix Inc A Delaware Corp Verbindungen und ihre verwendung in einer binären synthesestrategie
US5190029A (en) 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
WO1992015677A1 (en) 1991-03-01 1992-09-17 Protein Engineering Corporation Process for the development of binding mini-proteins
EP0580737B1 (en) 1991-04-10 2004-06-16 The Scripps Research Institute Heterodimeric receptor libraries using phagemids
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US7534567B2 (en) 1992-03-04 2009-05-19 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
ATE205542T1 (de) 1992-03-04 2001-09-15 Univ California Vergleichende genomhybridisierung
US5541061A (en) 1992-04-29 1996-07-30 Affymax Technologies N.V. Methods for screening factorial chemical libraries
US5376359A (en) 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US20040197774A1 (en) 1992-11-12 2004-10-07 Michael Wigler Representational approach to DNA analysis
WO1994015635A1 (en) 1993-01-11 1994-07-21 Dana-Farber Cancer Institute Inducing cytotoxic t lymphocyte responses
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US5858659A (en) 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
EP0730663B1 (en) 1993-10-26 2003-09-24 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
DE69527585T2 (de) 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US6287850B1 (en) 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
US6300063B1 (en) 1995-11-29 2001-10-09 Affymetrix, Inc. Polymorphism detection
CA2255774C (en) 1996-05-29 2008-03-18 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
ATE204290T1 (de) 1996-11-06 2001-09-15 Sequenom Inc Zusammensetzungen und verfahren zur immobilisierung von nukleinsäure auf festträgern
EP0878552A1 (en) 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US6210878B1 (en) 1997-08-08 2001-04-03 The Regents Of The University Of California Array-based detection of genetic alterations associated with disease
ATE537270T1 (de) 1997-10-30 2011-12-15 Cold Spring Harbor Lab Sondenanordnungen und deren verwendungen für verfahren zur dns-unterscheidung
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US20090304653A1 (en) 1998-01-30 2009-12-10 Evolutionary Genomics, Inc. Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US20030207295A1 (en) 1999-04-20 2003-11-06 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
EP1218397A4 (en) 1999-08-30 2003-04-23 Human Genome Sciences Inc ATTRACTIN-LIKE POLYNUCLEOTIDES, POLYPEPTIDES AND ANTIBODIES
US6423499B1 (en) 1999-09-10 2002-07-23 The United States Of America, As Represented By The Secretary Of Agriculture PCR primers for detection and identification of plant pathogenic species, subspecies, and strains of acidovorax
US6146834A (en) 1999-09-10 2000-11-14 The United States Of America As Represented By The Secretary Of Agriculture PCR primers for detection of plant pathogenic species and subspecies of acidovorax
US7211390B2 (en) 1999-09-16 2007-05-01 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7030231B1 (en) 1999-09-30 2006-04-18 Catalyst Biosciences, Inc. Membrane type serine protease 1 (MT-SP1) and uses thereof
US6251607B1 (en) 1999-12-09 2001-06-26 National Science Council Of Republic Of China PCR primers for the rapid and specific detection of Salmonella typhimurium
US6892141B1 (en) 2000-03-17 2005-05-10 Hitachi, Ltd. Primer design system
WO2001053460A1 (en) 2000-01-21 2001-07-26 Variagenics, Inc. Identification of genetic components of drug response
US6828097B1 (en) 2000-05-16 2004-12-07 The Childrens Mercy Hospital Single copy genomic hybridization probes and method of generating same
CA2426824A1 (en) 2000-10-24 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Direct multiplex characterization of genomic dna
US20040018491A1 (en) 2000-10-26 2004-01-29 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
JP2002242964A (ja) 2001-02-19 2002-08-28 Akebono Brake Ind Co Ltd ドラムブレーキ装置
AU785425B2 (en) 2001-03-30 2007-05-17 Genetic Technologies Limited Methods of genomic analysis
GB0113908D0 (en) 2001-06-07 2001-08-01 Univ London Designing degenerate PCR primers
US20030049663A1 (en) 2001-06-27 2003-03-13 Michael Wigler Use of reflections of DNA for genetic analysis
AU2002336421A1 (en) 2001-08-31 2003-04-14 The Government Of The United States Of America, Asrepresented By The Secretary Of The Department Of Measurements of multiple molecules using a cryoarray
US20030082606A1 (en) 2001-09-04 2003-05-01 Lebo Roger V. Optimizing genome-wide mutation analysis of chromosomes and genes
US6977148B2 (en) 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US20050124022A1 (en) 2001-10-30 2005-06-09 Maithreyan Srinivasan Novel sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US7107155B2 (en) 2001-12-03 2006-09-12 Dnaprint Genomics, Inc. Methods for the identification of genetic features for complex genetics classifiers
US6916621B2 (en) 2002-03-27 2005-07-12 Spectral Genomics, Inc. Methods for array-based comparitive binding assays
US7282330B2 (en) 2002-05-28 2007-10-16 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
AU2003262789A1 (en) 2002-08-20 2004-03-11 Aventis Pharma Sa Abca13 nucleic acids and proteins, and uses thereof
US7011949B2 (en) 2002-09-30 2006-03-14 Agilent Technologies, Inc. Methods and compositions for producing labeled probe nucleic acids for use in array based comparative genomic hybridization applications
US7822555B2 (en) 2002-11-11 2010-10-26 Affymetrix, Inc. Methods for identifying DNA copy number changes
US7424368B2 (en) 2002-11-11 2008-09-09 Affymetix, Inc. Methods for identifying DNA copy number changes
US10229244B2 (en) 2002-11-11 2019-03-12 Affymetrix, Inc. Methods for identifying DNA copy number changes using hidden markov model based estimations
ATE546525T1 (de) 2003-01-29 2012-03-15 454 Life Sciences Corp Nukleinsäureamplifikation auf basis von kügelchenemulsion
US20050021236A1 (en) 2003-02-14 2005-01-27 Oklahoma Medical Research Foundation And Intergenetics, Inc. Statistically identifying an increased risk for disease
NZ544235A (en) 2003-05-23 2009-12-24 Cold Spring Harbor Lab Virtual representations of nucleotide sequences
US20050053980A1 (en) 2003-06-20 2005-03-10 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
KR100647277B1 (ko) 2003-08-14 2006-11-17 삼성전자주식회사 B형 간염 검사용 pcr 프라이머 세트 및 이를 포함하는 b형 간염 검사 키트
US20070141577A1 (en) 2003-09-11 2007-06-21 Moore Thomas F Method
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
JP2008504803A (ja) 2004-01-09 2008-02-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 遺伝子発現の細胞型特異的パターン
US7910353B2 (en) 2004-02-13 2011-03-22 Signature Genomic Laboratories Methods and apparatuses for achieving precision genetic diagnoses
US20050233339A1 (en) 2004-04-20 2005-10-20 Barrett Michael T Methods and compositions for determining the relationship between hybridization signal of aCGH probes and target genomic DNA copy number
WO2005108621A1 (en) 2004-04-30 2005-11-17 Yale University Methods and compositions for cancer diagnosis
US20080166357A1 (en) 2004-05-11 2008-07-10 Stefan Golz Diagnostics and Therapeutics for Diseases Associated with Dipeptidyl-Peptidase 6 (Dpp6)
US20060024711A1 (en) 2004-07-02 2006-02-02 Helicos Biosciences Corporation Methods for nucleic acid amplification and sequence determination
US7276720B2 (en) 2004-07-19 2007-10-02 Helicos Biosciences Corporation Apparatus and methods for analyzing samples
US20060012793A1 (en) 2004-07-19 2006-01-19 Helicos Biosciences Corporation Apparatus and methods for analyzing samples
US20060024678A1 (en) 2004-07-28 2006-02-02 Helicos Biosciences Corporation Use of single-stranded nucleic acid binding proteins in sequencing
US7595159B2 (en) 2004-11-03 2009-09-29 The Brigham And Women's Hospital, Inc. Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
NO323175B1 (no) 2004-12-23 2007-01-15 Jan O Aasly Framgangsmate for a pavise en mutasjon som forarsaker arvelig parkinsonisme
WO2006091254A1 (en) 2005-02-18 2006-08-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Identification of molecular diagnostic markers for endometriosis in blood lymphocytes
CN100340674C (zh) 2005-04-28 2007-10-03 中国人民解放军总医院 耳聋相关基因突变及其检测方法
CA2607341A1 (en) 2005-05-05 2006-11-09 Mount Sinai Hospital Diagnosis and treatment of endometriosis
US8554488B2 (en) 2005-12-14 2013-10-08 Cold Spring Harbor Laboratory Determining a probabilistic diagnosis of autism by analysis of genomic copy number variations
CA2633203A1 (en) 2005-12-14 2007-06-21 Michael H. Wigler Use of roma for characterizing genomic rearrangements
WO2007092479A2 (en) 2006-02-06 2007-08-16 Lydia Machell Braille music systems and methods
PT2676967T (pt) 2006-02-28 2019-09-27 Biogen Ma Inc Métodos para tratamento de doenças inflamatórias e autoimunes com natalizumab
US20090191556A1 (en) 2006-04-12 2009-07-30 Medical Research Council Method
US7702468B2 (en) 2006-05-03 2010-04-20 Population Diagnostics, Inc. Evaluating genetic disorders
US10522240B2 (en) 2006-05-03 2019-12-31 Population Bio, Inc. Evaluating genetic disorders
CN101148684A (zh) 2006-09-22 2008-03-26 上海交通大学医学院附属瑞金医院 多发性内分泌腺瘤ii型基因突变检测的新方法
MX2009004798A (es) 2006-10-31 2009-08-12 Janssen Pharmaceutica Nv Tratamiento de los trastornos generalizados del desarrollo.
US20080131887A1 (en) 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
EP4134667B1 (en) 2006-12-14 2025-11-12 Life Technologies Corporation Apparatus for measuring analytes using fet arrays
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US20080305967A1 (en) 2007-06-11 2008-12-11 Juneau Biosciences, Llc Genetic Markers Associated with Endometriosis and Use Thereof
WO2009003147A1 (en) 2007-06-26 2008-12-31 Parkinson's Institute Methods and compositions for the treatment of neurological disorders
EP2200611A4 (en) 2007-09-14 2010-09-22 Biogen Idec Inc COMPOSITIONS AND METHODS FOR TREATING PROGRESSIVE MULTIFOCALER LEUKOENCEEPHALOPATHY (PML)
US20100248235A1 (en) 2007-10-04 2010-09-30 Scherer Stephen W Biomarkers for autism spectrum disorders
WO2009073764A1 (en) 2007-12-04 2009-06-11 University Of Miami Molecular targets for modulating intraocular pressure and differentiation of steroid responders versus non-responders
ES2381457T3 (es) 2007-12-28 2012-05-28 Pioneer Hi-Bred International Inc. Uso de una variación estructural para analizar diferencias genómicas para la predicción de heterosis
US8470594B2 (en) 2008-04-15 2013-06-25 President And Fellows Of Harvard College Methods for identifying agents that affect the survival of motor neurons
US8669048B2 (en) 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
EP2149613A1 (en) 2008-07-28 2010-02-03 Greenwood Genetic Center, Inc. Methods for determining dysregulation of methylation of brain expressed genes on the X chromosome to diagnose autism spectrum disorders
US20100035252A1 (en) 2008-08-08 2010-02-11 Ion Torrent Systems Incorporated Methods for sequencing individual nucleic acids under tension
WO2010036965A2 (en) 2008-09-25 2010-04-01 Suregene Llc Genetic markers of schizophrenia endophenotypes
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
CN101403008B (zh) 2008-11-07 2011-07-27 北京市神经外科研究所 一种检测成人早衰老综合症的基因诊断试剂盒
AU2009313999B2 (en) 2008-11-12 2016-09-29 Lineagen, Inc. Autism associated genetic markers
CA2766246C (en) 2008-11-14 2020-03-10 Hakon Hakonarson Genetic variants underlying human cognition and methods of use thereof as diagnostic and therapeutic targets
AU2010204995A1 (en) 2009-01-16 2011-08-18 Massachusetts Institute Of Technology Diagnosis and treatment of autism spectrum disorders
WO2010124101A2 (en) 2009-04-22 2010-10-28 Juneau Biosciences, Llc Genetic markers associated with endometriosis and use thereof
EP2459742B1 (en) 2009-07-29 2016-04-06 Pharnext New diagnostic tools for alzheimer disease
WO2011035012A2 (en) 2009-09-16 2011-03-24 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for diagnosing heart failure
CA2782207A1 (en) 2009-11-30 2011-06-03 23Andme, Inc. Polymorphisms associated with parkinson's disease
WO2011112961A1 (en) 2010-03-12 2011-09-15 Children's Medical Center Corporation Methods and compositions for characterizing autism spectrum disorder based on gene expression patterns
CN103392182B (zh) 2010-08-02 2017-07-04 众有生物有限公司 用于发现遗传疾病中致病突变的系统和方法
CN103069572B (zh) 2010-08-17 2016-01-20 凸版印刷株式会社 化合物半导体薄膜制作用油墨、使用该油墨获得的化合物半导体薄膜、具备该化合物半导体薄膜的太阳能电池及该太阳能电池的制造方法
EP2609220B1 (en) 2010-08-24 2018-06-27 The Children's Hospital of Philadelphia Association of rare recurrent genetic variations to attention-deficit, hyperactivity disorder (adhd) and methods of use thereof for the diagnosis and treatment of the same
CA2744424A1 (en) 2010-09-14 2012-03-14 The Hospital For Sick Children Biomarkers for autism spectrum disorders
AU2010361988A1 (en) 2010-10-07 2013-05-02 Integragen Sa Compositions and methods for diagnosing autism
WO2012135468A2 (en) 2011-03-29 2012-10-04 Cornell University Genetics of gender discrimination in date palm
WO2013054200A2 (en) 2011-10-10 2013-04-18 The Hospital For Sick Children Methods and compositions for screening and treating developmental disorders
WO2013067451A2 (en) 2011-11-04 2013-05-10 Population Diagnostics Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
WO2013071119A2 (en) 2011-11-10 2013-05-16 Genentech, Inc Methods for treating, diagnosing and monitoring alzheimer's disease
EP2812452B1 (en) 2012-02-09 2020-05-27 Population Bio, Inc. Methods and compositions for screening and treating developmental disorders
US9481889B2 (en) 2012-03-19 2016-11-01 The Malasian Palm Oil Board Gene controlling shell phenotype in palm
US10995342B2 (en) 2012-05-11 2021-05-04 Wisconsin Alumni Research Foundation Rhg1 mediated resistance to soybean cyst nematode
US9976180B2 (en) 2012-09-14 2018-05-22 Population Bio, Inc. Methods for detecting a genetic variation in subjects with parkinsonism
EP2900835B1 (en) 2012-09-27 2025-04-30 Population Bio, Inc. Method for screening and treating developmental disorders
CN103436606B (zh) 2013-08-01 2014-10-29 中山大学附属肿瘤医院 一种用于食管癌辅助诊断和/或预后判断的试剂盒
DK2891722T3 (en) 2013-11-12 2019-01-07 Population Bio Inc METHODS AND COMPOSITIONS FOR DIAGNOSTICING, PROGRAMMING AND TREATMENT OF ENDOMETRIOSIS
EP3757224A3 (en) 2014-02-27 2021-03-17 Biogen MA Inc. Method of assessing risk of pml
JP2016031772A (ja) 2014-07-30 2016-03-07 株式会社日立ハイテクファインシステムズ 熱アシスト磁気ヘッド素子の検査方法及びその装置
CA2996445A1 (en) 2014-09-05 2016-03-10 Eli Hatchwell Methods and compositions for inhibiting and treating neurological conditions
US10045575B2 (en) 2016-02-02 2018-08-14 Camilo Arturo Whyte Transformable arm-ware for recreational activities
DE102017200145B4 (de) * 2016-01-22 2021-12-23 Ford Global Technologies, Llc Verfahren zur Überwachung einer Abgasnachbehandlungsanlage, insbesondere eines NOx-Speicher-Katalysators sowie Steuerungseinrichtung für eine Abgasnachbehandlungsanlage und Fahrzeug
US10240205B2 (en) 2017-02-03 2019-03-26 Population Bio, Inc. Methods for assessing risk of developing a viral disease using a genetic test
SI3625368T1 (sl) * 2018-08-08 2023-04-28 Pml Screening, Llc Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham

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