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SI3529248T1 - Farmacevtske spojine - Google Patents

Farmacevtske spojine

Info

Publication number
SI3529248T1
SI3529248T1 SI201730402T SI201730402T SI3529248T1 SI 3529248 T1 SI3529248 T1 SI 3529248T1 SI 201730402 T SI201730402 T SI 201730402T SI 201730402 T SI201730402 T SI 201730402T SI 3529248 T1 SI3529248 T1 SI 3529248T1
Authority
SI
Slovenia
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Application number
SI201730402T
Other languages
English (en)
Inventor
Neil Anthony Pegg
Stuart Thomas Onions
David Michel Adrien Taddei
Jonathan Shannon
Silvia Paoletta
Richard James Brown
Don Smyth
Gareth Harbottle
Original Assignee
Cellcentric Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellcentric Ltd filed Critical Cellcentric Ltd
Publication of SI3529248T1 publication Critical patent/SI3529248T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201730402T 2016-10-18 2017-10-18 Farmacevtske spojine SI3529248T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1617630.7A GB201617630D0 (en) 2016-10-18 2016-10-18 Pharmaceutical compounds
EP17790813.4A EP3529248B1 (en) 2016-10-18 2017-10-18 Pharmaceutical compounds
PCT/GB2017/053152 WO2018073586A1 (en) 2016-10-18 2017-10-18 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
SI3529248T1 true SI3529248T1 (sl) 2020-11-30

Family

ID=57680668

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201730402T SI3529248T1 (sl) 2016-10-18 2017-10-18 Farmacevtske spojine

Country Status (24)

Country Link
US (2) US10696666B2 (sl)
EP (1) EP3529248B1 (sl)
JP (1) JP7152393B2 (sl)
KR (1) KR102578786B1 (sl)
CN (1) CN110049983B (sl)
AU (1) AU2017346453B2 (sl)
CA (1) CA3039641A1 (sl)
CY (1) CY1123666T1 (sl)
DK (1) DK3529248T3 (sl)
EA (1) EA201990643A1 (sl)
ES (1) ES2828504T3 (sl)
GB (1) GB201617630D0 (sl)
HR (1) HRP20201444T1 (sl)
HU (1) HUE052443T2 (sl)
IL (1) IL266017B (sl)
LT (1) LT3529248T (sl)
MX (1) MX384438B (sl)
PT (1) PT3529248T (sl)
RS (1) RS61007B1 (sl)
SG (1) SG11201903155XA (sl)
SI (1) SI3529248T1 (sl)
SM (1) SMT202000593T1 (sl)
WO (1) WO2018073586A1 (sl)
ZA (1) ZA201902334B (sl)

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GB201617630D0 (en) 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
GB201617627D0 (en) * 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
MA50250A (fr) 2017-09-15 2020-07-22 Forma Therapeutics Inc Compositions de tétrahydroimidazo quinoléine utilisées en tant qu'inhibiteurs de cbp/p300
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KR20250067962A (ko) 2018-06-29 2025-05-15 포르마 세라퓨틱스 인크. Creb 결합 단백질(cbp)의 저해
CN113874017B (zh) * 2019-03-15 2024-11-22 福马治疗股份有限公司 抑制环amp-应答元件结合蛋白(creb)
TW202102494A (zh) 2019-03-15 2021-01-16 美商弗瑪治療公司 抑制環amp-反應元件-結合蛋白(creb)
CN112574189B (zh) * 2019-09-27 2024-05-31 海创药业股份有限公司 一种ep300/cbp抑制剂
CN112574178B (zh) * 2019-09-27 2025-12-16 海创药业股份有限公司 一种氘代苯并咪唑类化合物及其作为ep300/cbp抑制剂的用途
CN112574191B (zh) * 2019-09-29 2024-01-23 南京圣和药业股份有限公司 异噁唑杂环类化合物及其应用
KR20230028798A (ko) 2020-06-25 2023-03-02 톨레모 테라퓨틱스 아게 암 치료를 위한 CBP/p300 브로모도메인 억제제 및 KRAS 억제제의 조합물
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Also Published As

Publication number Publication date
DK3529248T3 (da) 2020-09-14
AU2017346453B2 (en) 2022-02-17
CN110049983A (zh) 2019-07-23
IL266017A (en) 2019-06-30
PT3529248T (pt) 2020-09-03
MX2019004113A (es) 2019-09-09
EP3529248B1 (en) 2020-08-19
US11377443B2 (en) 2022-07-05
CA3039641A1 (en) 2018-04-26
WO2018073586A1 (en) 2018-04-26
ES2828504T3 (es) 2021-05-26
EA201990643A1 (ru) 2019-11-29
US20190375740A1 (en) 2019-12-12
SMT202000593T1 (it) 2020-11-10
HRP20201444T1 (hr) 2020-12-11
KR102578786B1 (ko) 2023-09-15
LT3529248T (lt) 2020-10-26
CN110049983B (zh) 2022-06-14
CY1123666T1 (el) 2022-03-24
KR20190075095A (ko) 2019-06-28
HUE052443T2 (hu) 2021-04-28
NZ752354A (en) 2025-02-28
MX384438B (es) 2025-03-14
RS61007B1 (sr) 2020-11-30
US10696666B2 (en) 2020-06-30
SG11201903155XA (en) 2019-05-30
JP2019537571A (ja) 2019-12-26
GB201617630D0 (en) 2016-11-30
BR112019007834A2 (pt) 2019-07-16
ZA201902334B (en) 2022-10-26
IL266017B (en) 2021-08-31
US20200407349A1 (en) 2020-12-31
JP7152393B2 (ja) 2022-10-12
AU2017346453A1 (en) 2019-05-02
EP3529248A1 (en) 2019-08-28

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