SI3448430T1 - Uporaba inhibitorja acetilholinesteraze in idalopirdina za zmanjšanje padcev pri bolnikih s parkinsonovo boleznijo - Google Patents
Uporaba inhibitorja acetilholinesteraze in idalopirdina za zmanjšanje padcev pri bolnikih s parkinsonovo boleznijoInfo
- Publication number
- SI3448430T1 SI3448430T1 SI201731371T SI201731371T SI3448430T1 SI 3448430 T1 SI3448430 T1 SI 3448430T1 SI 201731371 T SI201731371 T SI 201731371T SI 201731371 T SI201731371 T SI 201731371T SI 3448430 T1 SI3448430 T1 SI 3448430T1
- Authority
- SI
- Slovenia
- Prior art keywords
- idalopirdine
- parkinson
- patients
- disease
- acetylcholinesterase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201600248 | 2016-04-26 | ||
| EP17719255.6A EP3448430B1 (en) | 2016-04-26 | 2017-04-25 | Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in parkinson's disease patients |
| PCT/EP2017/059739 WO2017186686A1 (en) | 2016-04-26 | 2017-04-25 | Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in parkinson's disease patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3448430T1 true SI3448430T1 (sl) | 2023-08-31 |
Family
ID=58632402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201731371T SI3448430T1 (sl) | 2016-04-26 | 2017-04-25 | Uporaba inhibitorja acetilholinesteraze in idalopirdina za zmanjšanje padcev pri bolnikih s parkinsonovo boleznijo |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US10383849B2 (sl) |
| EP (1) | EP3448430B1 (sl) |
| JP (1) | JP6992004B2 (sl) |
| KR (1) | KR102473545B1 (sl) |
| CN (3) | CN118806909A (sl) |
| AU (1) | AU2017256623B2 (sl) |
| BR (1) | BR112017026928B1 (sl) |
| CA (1) | CA3020557C (sl) |
| CL (1) | CL2018003013A1 (sl) |
| CY (1) | CY1126138T1 (sl) |
| DK (1) | DK3448430T3 (sl) |
| ES (1) | ES2949288T3 (sl) |
| FI (1) | FI3448430T3 (sl) |
| HR (1) | HRP20230693T8 (sl) |
| HU (1) | HUE062626T2 (sl) |
| IL (1) | IL262546B (sl) |
| LT (1) | LT3448430T (sl) |
| MX (1) | MX387444B (sl) |
| PL (1) | PL3448430T3 (sl) |
| PT (1) | PT3448430T (sl) |
| RS (1) | RS64307B1 (sl) |
| RU (1) | RU2742173C2 (sl) |
| SG (1) | SG11201809297UA (sl) |
| SI (1) | SI3448430T1 (sl) |
| SM (1) | SMT202300197T1 (sl) |
| TW (1) | TW201806621A (sl) |
| WO (1) | WO2017186686A1 (sl) |
| ZA (1) | ZA201806864B (sl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202100240T1 (it) | 2017-05-24 | 2021-05-07 | H Lundbeck As | Combinazione di un antagonista del recettore di 5-ht6 e un inibitore della acetilcolinesterasi per l'uso nel trattamento della malattia di alzheimer in una sottopopolazione di pazienti portatori di alleli apoe4 |
| WO2019240740A1 (en) * | 2017-12-22 | 2019-12-19 | Arasteh Ari Azhir | Compositions and methods for treatment related to fall and fall frequency in neurodegenerative diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9818914D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
| KR100894189B1 (ko) * | 2001-03-29 | 2009-04-22 | 일라이 릴리 앤드 캄파니 | 5-ht6 수용체의 길항제로서의 n-(2-아릴에틸)벤질아민 |
| EP1871368B1 (en) * | 2005-04-04 | 2011-06-08 | Eisai R&D Management Co., Ltd. | Dihydropyridine compounds for neurodegenerative diseases and dementia |
| PE20071143A1 (es) * | 2006-01-13 | 2008-01-20 | Wyeth Corp | Composicion farmaceutica que comprende un inhibidor de acetilcolinesterasa y un antagonista 5-hidroxitriptamina-6 |
| PT2040755E (pt) * | 2006-06-23 | 2011-07-08 | Esteve Labor Dr | Combinação de um inibidor de colinesterase e um composto com afinidade para o receptor 5-ht6 |
| WO2009074607A1 (en) * | 2007-12-12 | 2009-06-18 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
| RU2393158C1 (ru) * | 2008-10-06 | 2010-06-27 | Андрей Александрович Иващенко | ЗАМЕЩЕННЫЕ 3-АРИЛСУЛЬФОНИЛ-ПИРАЗОЛО[1,5-а]ПИРИМИДИНЫ, АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ |
| JO3459B1 (ar) * | 2012-09-09 | 2020-07-05 | H Lundbeck As | تركيبات صيدلانية لعلاج مرض الزهايمر |
-
2017
- 2017-04-25 CN CN202410836839.2A patent/CN118806909A/zh active Pending
- 2017-04-25 JP JP2018555748A patent/JP6992004B2/ja active Active
- 2017-04-25 DK DK17719255.6T patent/DK3448430T3/da active
- 2017-04-25 SG SG11201809297UA patent/SG11201809297UA/en unknown
- 2017-04-25 US US15/496,159 patent/US10383849B2/en active Active
- 2017-04-25 AU AU2017256623A patent/AU2017256623B2/en active Active
- 2017-04-25 PT PT177192556T patent/PT3448430T/pt unknown
- 2017-04-25 SI SI201731371T patent/SI3448430T1/sl unknown
- 2017-04-25 KR KR1020187030934A patent/KR102473545B1/ko active Active
- 2017-04-25 ES ES17719255T patent/ES2949288T3/es active Active
- 2017-04-25 RS RS20230489A patent/RS64307B1/sr unknown
- 2017-04-25 SM SM20230197T patent/SMT202300197T1/it unknown
- 2017-04-25 CN CN201780025728.1A patent/CN109069650A/zh active Pending
- 2017-04-25 WO PCT/EP2017/059739 patent/WO2017186686A1/en not_active Ceased
- 2017-04-25 HU HUE17719255A patent/HUE062626T2/hu unknown
- 2017-04-25 HR HRP20230693TT patent/HRP20230693T8/hr unknown
- 2017-04-25 RU RU2018135846A patent/RU2742173C2/ru active
- 2017-04-25 LT LTEPPCT/EP2017/059739T patent/LT3448430T/lt unknown
- 2017-04-25 CN CN202410836842.4A patent/CN118806910A/zh active Pending
- 2017-04-25 TW TW106113760A patent/TW201806621A/zh unknown
- 2017-04-25 FI FIEP17719255.6T patent/FI3448430T3/fi active
- 2017-04-25 CA CA3020557A patent/CA3020557C/en active Active
- 2017-04-25 BR BR112017026928-7A patent/BR112017026928B1/pt active IP Right Grant
- 2017-04-25 MX MX2018013031A patent/MX387444B/es unknown
- 2017-04-25 EP EP17719255.6A patent/EP3448430B1/en active Active
- 2017-04-25 PL PL17719255.6T patent/PL3448430T3/pl unknown
-
2018
- 2018-10-15 ZA ZA2018/06864A patent/ZA201806864B/en unknown
- 2018-10-24 CL CL2018003013A patent/CL2018003013A1/es unknown
- 2018-10-24 IL IL262546A patent/IL262546B/en unknown
-
2023
- 2023-08-04 CY CY20231100395T patent/CY1126138T1/el unknown
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