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SI3305768T1 - Natrijeva sol inhibitorja transporterja sečne kisline in kristalinična oblika le-te - Google Patents

Natrijeva sol inhibitorja transporterja sečne kisline in kristalinična oblika le-te

Info

Publication number
SI3305768T1
SI3305768T1 SI201630871T SI201630871T SI3305768T1 SI 3305768 T1 SI3305768 T1 SI 3305768T1 SI 201630871 T SI201630871 T SI 201630871T SI 201630871 T SI201630871 T SI 201630871T SI 3305768 T1 SI3305768 T1 SI 3305768T1
Authority
SI
Slovenia
Prior art keywords
sodium salt
crystalline form
uric acid
acid transporter
transporter inhibitor
Prior art date
Application number
SI201630871T
Other languages
English (en)
Inventor
Guaili Wu
Zhenjun Qiu
Yunpeng Su
Xi Lu
Original Assignee
Jiangsu Hengrui Medicine Co., Ltd.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Medicine Co., Ltd., filed Critical Jiangsu Hengrui Medicine Co., Ltd.,
Publication of SI3305768T1 publication Critical patent/SI3305768T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
SI201630871T 2015-05-27 2016-05-26 Natrijeva sol inhibitorja transporterja sečne kisline in kristalinična oblika le-te SI3305768T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510280720 2015-05-27
EP16799331.0A EP3305768B1 (en) 2015-05-27 2016-05-26 Sodium salt of uric acid transporter inhibitor and crystalline form thereof
PCT/CN2016/083423 WO2016188444A1 (zh) 2015-05-27 2016-05-26 一种尿酸转运蛋白抑制剂的钠盐及其结晶形式

Publications (1)

Publication Number Publication Date
SI3305768T1 true SI3305768T1 (sl) 2020-10-30

Family

ID=57393793

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201630871T SI3305768T1 (sl) 2015-05-27 2016-05-26 Natrijeva sol inhibitorja transporterja sečne kisline in kristalinična oblika le-te

Country Status (22)

Country Link
US (2) US10196361B2 (sl)
EP (1) EP3305768B1 (sl)
JP (1) JP6738350B2 (sl)
KR (1) KR20180006441A (sl)
CN (1) CN107001276B (sl)
AU (1) AU2016269359B2 (sl)
BR (1) BR112017022505A2 (sl)
CA (1) CA2984961C (sl)
CY (1) CY1123262T1 (sl)
DK (1) DK3305768T3 (sl)
ES (1) ES2811325T3 (sl)
HR (1) HRP20201178T1 (sl)
HU (1) HUE051640T2 (sl)
LT (1) LT3305768T (sl)
MX (1) MX379184B (sl)
PL (1) PL3305768T3 (sl)
PT (1) PT3305768T (sl)
RS (1) RS60749B1 (sl)
RU (1) RU2719484C2 (sl)
SI (1) SI3305768T1 (sl)
SM (1) SMT202000421T1 (sl)
WO (1) WO2016188444A1 (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3305768T (pt) * 2015-05-27 2020-08-03 Jiangsu Hengrui Medicine Co Sal de sódio de um inibidor do transportador do ácido úrico e forma cristalina do mesmo
CN108201529B (zh) * 2016-12-16 2021-10-08 江苏恒瑞医药股份有限公司 一种含有尿酸转运蛋白抑制剂的药物组合物及其制备方法
CN110467571B (zh) * 2018-05-11 2021-02-26 江苏恒瑞医药股份有限公司 一种制备环烷基甲酸类衍生物或其可药用盐的方法
WO2025072489A2 (en) 2023-09-27 2025-04-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SA04250253B1 (ar) * 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
PL2998296T3 (pl) * 2013-05-13 2018-12-31 Shanghai Hengrui Pharmaceutical Co. Ltd. Pochodna kwasu cykloalkilowego, sposób jej otrzymywania i jej zastosowanie farmaceutyczne
PT3305768T (pt) * 2015-05-27 2020-08-03 Jiangsu Hengrui Medicine Co Sal de sódio de um inibidor do transportador do ácido úrico e forma cristalina do mesmo

Also Published As

Publication number Publication date
HRP20201178T1 (hr) 2020-11-13
EP3305768B1 (en) 2020-07-01
US20190040015A1 (en) 2019-02-07
MX2017014319A (es) 2018-03-07
EP3305768A4 (en) 2019-02-13
HUE051640T2 (hu) 2021-03-01
ES2811325T3 (es) 2021-03-11
RS60749B1 (sr) 2020-10-30
RU2719484C2 (ru) 2020-04-17
PL3305768T3 (pl) 2020-12-28
CA2984961A1 (en) 2016-12-01
WO2016188444A1 (zh) 2016-12-01
RU2017142996A (ru) 2019-06-27
EP3305768A1 (en) 2018-04-11
BR112017022505A2 (pt) 2018-07-17
AU2016269359A1 (en) 2017-11-23
US20180134663A1 (en) 2018-05-17
PT3305768T (pt) 2020-08-03
DK3305768T3 (da) 2020-08-10
RU2017142996A3 (sl) 2019-11-20
AU2016269359B2 (en) 2020-02-06
CY1123262T1 (el) 2021-12-31
SMT202000421T1 (it) 2020-09-10
JP2018515454A (ja) 2018-06-14
CA2984961C (en) 2023-08-01
MX379184B (es) 2025-03-10
CN107001276A (zh) 2017-08-01
JP6738350B2 (ja) 2020-08-12
CN107001276B (zh) 2020-03-13
US10358424B2 (en) 2019-07-23
KR20180006441A (ko) 2018-01-17
LT3305768T (lt) 2020-08-25
US10196361B2 (en) 2019-02-05

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