SI2489743T1 - Aptameri s 5-(N-naftilno) substituiranimi uridini - Google Patents

Aptameri s 5-(N-naftilno) substituiranimi uridini

Info

Publication number: SI2489743T1
Authority: SI; Slovenia
Prior art keywords: aptamers; naphthyl; substituted uridines; uridines; substituted
Prior art date: 2007-07-17

Application number

SI200831408T

Other languages

English (en)

Inventor

Dominic Zichi

Sheri K. Wilcox

Chris Bock

Daniel J. Schneider

Bruce Eaton

Larry Gold

Original Assignee

Somalogic, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-17

Filing date

2008-07-17

Publication date

2015-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40260081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2489743(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-07-17 Application filed by Somalogic, Inc. filed Critical Somalogic, Inc.

2015-04-30 Publication of SI2489743T1 publication Critical patent/SI2489743T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
- C12N2310/334—Modified C
- C12N2310/3341—5-Methylcytosine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/13—Applications; Uses in screening processes in a process of directed evolution, e.g. SELEX, acquiring a new function
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/205—Aptamer
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2541/00—Reactions characterised by directed evolution
- C12Q2541/10—Reactions characterised by directed evolution the purpose being the selection or design of target specific nucleic acid binding sequences
- C12Q2541/101—Selex

Landscapes

Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Crystallography & Structural Chemistry (AREA)
Bioinformatics & Computational Biology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Photometry And Measurement Of Optical Pulse Characteristics (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI200831408T 2007-07-17 2008-07-17 Aptameri s 5-(N-naftilno) substituiranimi uridini SI2489743T1 (sl)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US95028107P	2007-07-17	2007-07-17
US95028307P	2007-07-17	2007-07-17
US95029307P	2007-07-17	2007-07-17
US3142008P	2008-02-26	2008-02-26
US5159408P	2008-05-08	2008-05-08
EP12160299.9A EP2489743B1 (en)	2007-07-17	2008-07-17	Aptamers with 5-(N-naphthyl)-substituted uridines

Publications (1)

Publication Number	Publication Date
SI2489743T1 true SI2489743T1 (sl)	2015-04-30

Family

ID=40260081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200831408T SI2489743T1 (sl)	2007-07-17	2008-07-17	Aptameri s 5-(N-naftilno) substituiranimi uridini

Country Status (17)

Country	Link
US (1)	US8409795B2 (sl)
EP (10)	EP2076613B1 (sl)
JP (11)	JP5684568B2 (sl)
KR (3)	KR101656240B1 (sl)
CN (6)	CN107090457A (sl)
AU (3)	AU2008275915B2 (sl)
CA (4)	CA3022666C (sl)
DK (4)	DK2172566T4 (sl)
ES (6)	ES2604764T3 (sl)
FI (1)	FI3284832T3 (sl)
HR (1)	HRP20150382T1 (sl)
MX (7)	MX2010000533A (sl)
NO (1)	NO2933340T3 (sl)
PL (1)	PL2489743T3 (sl)
PT (2)	PT2489743E (sl)
SI (1)	SI2489743T1 (sl)
WO (3)	WO2009012410A1 (sl)

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2014
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2015
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Also Published As

Publication number	Publication date
EP2076613B1 (en)	2016-09-07
ES2647587T3 (es)	2017-12-22
CA2693453C (en)	2018-12-11
DK2172566T3 (en)	2015-05-04
CN118064441A (zh)	2024-05-24
EP2069529A2 (en)	2009-06-17
EP2069529A4 (en)	2009-12-30
AU2008276001A2 (en)	2010-06-03
JP5938080B2 (ja)	2016-06-22
CN103627792A (zh)	2014-03-12
EP2069496A4 (en)	2010-01-27
KR101747665B1 (ko)	2017-06-15
JP2016122014A (ja)	2016-07-07
EP2076613A4 (en)	2012-11-28
CN101809167A (zh)	2010-08-18
KR101656240B1 (ko)	2016-09-09
EP4056711B1 (en)	2025-09-03
EP3284832A3 (en)	2018-03-07
JP2010533872A (ja)	2010-10-28
JP2015062416A (ja)	2015-04-09
JP2016171810A (ja)	2016-09-29
JP5404620B2 (ja)	2014-02-05
AU2008276001A1 (en)	2009-01-22
US20090098549A1 (en)	2009-04-16
WO2009012410A1 (en)	2009-01-22
MX2010000578A (es)	2010-04-30
US8409795B2 (en)	2013-04-02
MX355017B (es)	2018-04-02
CN104593373A (zh)	2015-05-06
HK1213020A1 (en)	2016-06-24
DK2489743T3 (en)	2015-03-02
ES2533711T3 (es)	2015-04-14
ES3045958T3 (en)	2025-12-01
ES2537322T5 (es)	2022-09-12
JP2014050398A (ja)	2014-03-20
HK1141839A1 (en)	2010-11-19
EP2336314A1 (en)	2011-06-22
ES2951068T3 (es)	2023-10-17
ES2604764T3 (es)	2017-03-09
WO2009012418A3 (en)	2009-03-05
EP2172566B1 (en)	2015-03-04
JP5684568B2 (ja)	2015-03-11
MX2020009595A (es)	2020-10-07
AU2008275915B2 (en)	2013-07-11
JP6491610B2 (ja)	2019-03-27
CA3022666A1 (en)	2009-01-22
CN101809167B (zh)	2015-04-01
PT2172566E (pt)	2015-06-23
EP2069496A1 (en)	2009-06-17
CN101802225A (zh)	2010-08-11
JP7755619B2 (ja)	2025-10-16
KR20160108584A (ko)	2016-09-19
HK1246368A1 (en)	2018-09-07
JP5956404B2 (ja)	2016-07-27
AU2008275917B2 (en)	2014-08-21
FI3284832T3 (fi)	2023-08-01
EP4056711C0 (en)	2025-09-03
NO2933340T3 (sl)	2018-02-03
EP2069529B1 (en)	2013-01-09
EP2489743A2 (en)	2012-08-22
EP2933340A1 (en)	2015-10-21
EP3284832A2 (en)	2018-02-21
EP2076613A1 (en)	2009-07-08
DK2172566T4 (da)	2022-06-13
MX375114B (es)	2025-03-06
KR101634608B1 (ko)	2016-06-29
AU2008275917A1 (en)	2009-01-22
MX2010000533A (es)	2010-04-30
HK1133046A1 (en)	2010-03-12
EP2933340B1 (en)	2017-09-06
JP2019039929A (ja)	2019-03-14
MX341491B (es)	2016-08-23
EP2172566A1 (en)	2010-04-07
JP2021129577A (ja)	2021-09-09
EP4056711A1 (en)	2022-09-14
DK2069529T3 (da)	2013-04-15
AU2008275917A2 (en)	2010-04-29
JP2019004901A (ja)	2019-01-17
AU2008276001A9 (en)	2010-06-10
HK1132012A1 (zh)	2010-02-12
JP2023116788A (ja)	2023-08-22
CA2696431C (en)	2021-01-05
CA3022666C (en)	2022-04-19
MX344253B (es)	2016-12-09
CA2696431A1 (en)	2009-01-22
AU2008275915A2 (en)	2010-04-22
CA2693448A1 (en)	2009-01-22
CA2693453A1 (en)	2009-01-22
KR20100058485A (ko)	2010-06-03
HK1174366A1 (en)	2013-06-07
DK3284832T5 (da)	2024-10-07
JP2020078311A (ja)	2020-05-28
CN101802225B (zh)	2013-10-30
KR20100044787A (ko)	2010-04-30
EP2626436A2 (en)	2013-08-14
DK3284832T3 (da)	2023-07-31
CN107090457A (zh)	2017-08-25
EP2172566B2 (en)	2022-05-18
JP7303244B2 (ja)	2023-07-04
ES2537322T3 (es)	2015-06-05
EP2489743B1 (en)	2015-01-07
PL2489743T3 (pl)	2015-06-30
EP2626436A3 (en)	2013-10-16
JP2010533499A (ja)	2010-10-28
WO2009012418A2 (en)	2009-01-22
EP3284832B1 (en)	2023-06-07
AU2008275915A1 (en)	2009-01-22
JP6407195B2 (ja)	2018-10-17
EP2489743A3 (en)	2012-11-21
PT2489743E (pt)	2015-04-09
WO2009012420A1 (en)	2009-01-22
HRP20150382T1 (hr)	2015-05-08

Publication	Publication Date	Title
PL2489743T3 (pl)	2015-06-30	Aptamery z 5-(N-naftylo)-podstawionymi urydynami
EP2156345A4 (en)	2012-05-23	PROXIMITY STORE SOLUTIONS
GB0809386D0 (en)	2008-07-02	Transferring funds electronically
PL2514818T3 (pl)	2014-11-28	Odmiany glukoamylazy
GB2473294B (en)	2014-07-09	Dynamics control
IL207626A0 (en)	2010-12-30	Ballistic transparency
PL2356432T3 (pl)	2018-06-29	Urządzenie czujnikowe
GB2458369B (en)	2011-08-31	Steerable projectile
EP2183771A4 (en)	2012-03-07	TRANSPORT SYSTEM WITH BUFFER
EP2352888A4 (en)	2012-12-26	FRAME
GB0805263D0 (en)	2008-04-30	Sensor arrangement
HU3689U (en)	2009-12-28	Videodetector with pmo sensor
PL2146030T3 (pl)	2012-05-31	Klucz płaski
GB0711922D0 (en)	2007-08-01	Control arrangement
PL2217505T3 (pl)	2014-12-31	Układ transportowy
GB0810580D0 (en)	2008-07-16	A personal transport system
PL2322895T3 (pl)	2014-06-30	Korpus pocisku wyposażony w rozkładane powierzchnie sterowe
GB0805833D0 (en)	2008-04-30	Swap parition
GB2480589B (en)	2015-12-02	Externally heated engine
GB0819774D0 (en)	2008-12-03	SMA control algorithm improvememts
GB0816589D0 (en)	2008-10-15	Transporting fuels
PL385621A1 (pl)	2009-11-23	Pocisk
GB0805247D0 (en)	2008-04-30	Weapon
GB0811576D0 (en)	2008-07-30	Suitcase with improved carrying capacity
GB0807370D0 (en)	2008-05-28	Associative memory