SI2451438T1 - Farmacevtski sestavek za inhibitor virusne proteaze hepatitisa C - Google Patents
Farmacevtski sestavek za inhibitor virusne proteaze hepatitisa CInfo
- Publication number
- SI2451438T1 SI2451438T1 SI201030565T SI201030565T SI2451438T1 SI 2451438 T1 SI2451438 T1 SI 2451438T1 SI 201030565 T SI201030565 T SI 201030565T SI 201030565 T SI201030565 T SI 201030565T SI 2451438 T1 SI2451438 T1 SI 2451438T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hepatitis
- pharmaceutical composition
- protease inhibitor
- viral protease
- viral
- Prior art date
Links
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 title 1
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22350709P | 2009-07-07 | 2009-07-07 | |
| EP10731685.3A EP2451438B8 (en) | 2009-07-07 | 2010-07-01 | Pharmaceutical composition for a hepatitis c viral protease inhibitor |
| PCT/US2010/040734 WO2011005646A2 (en) | 2009-07-07 | 2010-07-01 | Pharmaceutical composition for a hepatitis c viral protease inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2451438T1 true SI2451438T1 (sl) | 2014-04-30 |
Family
ID=43245003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201030565T SI2451438T1 (sl) | 2009-07-07 | 2010-07-01 | Farmacevtski sestavek za inhibitor virusne proteaze hepatitisa C |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US9034831B2 (sl) |
| EP (1) | EP2451438B8 (sl) |
| JP (1) | JP5607736B2 (sl) |
| KR (1) | KR101685941B1 (sl) |
| CN (1) | CN102470103B (sl) |
| AP (1) | AP2011005979A0 (sl) |
| AR (1) | AR077393A1 (sl) |
| AU (1) | AU2010270783B2 (sl) |
| BR (1) | BR112012000287B8 (sl) |
| CA (1) | CA2767692C (sl) |
| CL (1) | CL2012000054A1 (sl) |
| CO (1) | CO6480980A2 (sl) |
| DK (1) | DK2451438T3 (sl) |
| EA (1) | EA023433B1 (sl) |
| EC (1) | ECSP12011624A (sl) |
| ES (1) | ES2464367T3 (sl) |
| GE (1) | GEP20146016B (sl) |
| HR (1) | HRP20140445T1 (sl) |
| IL (1) | IL216098A (sl) |
| MA (1) | MA33491B1 (sl) |
| ME (1) | ME01718B (sl) |
| MX (1) | MX2011013824A (sl) |
| MY (1) | MY154683A (sl) |
| NZ (1) | NZ596928A (sl) |
| PE (1) | PE20120322A1 (sl) |
| PL (1) | PL2451438T3 (sl) |
| PT (1) | PT2451438E (sl) |
| RS (1) | RS53209B (sl) |
| SG (1) | SG177569A1 (sl) |
| SI (1) | SI2451438T1 (sl) |
| TN (1) | TN2012000009A1 (sl) |
| TW (1) | TWI490216B (sl) |
| UA (1) | UA104195C2 (sl) |
| UY (1) | UY32760A (sl) |
| WO (1) | WO2011005646A2 (sl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5539363B2 (ja) * | 2008-09-17 | 2014-07-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インターフェロンおよびリバビリンとのhcvns3プロテアーゼ阻害剤の組合せ |
| PL2451438T3 (pl) | 2009-07-07 | 2014-07-31 | Boehringer Ingelheim Int | Kompozycja farmaceutyczna inhibitora proteazy wirusowego zapalenia wątroby typu C |
| JP2013508425A (ja) | 2009-10-30 | 2013-03-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Bi201335、インターフェロンアルファおよびリバビリンを含むhcvの併用療法のための投薬処置計画 |
| CA2813093A1 (en) | 2010-09-30 | 2012-04-05 | Boehringer Ingelheim International Gmbh | Combination therapy for treating hcv infection |
| US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CH707030B1 (de) | 2011-10-21 | 2015-03-13 | Abbvie Inc | Kombinationsbehandlung von DAAs zur Verwendung in der Behandlung von HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| ES2529143B1 (es) | 2011-10-21 | 2015-10-26 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa, ribavirina pero no interferón para uso de tratamiento del vhc |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| EP2802313A1 (en) * | 2012-01-12 | 2014-11-19 | Boehringer Ingelheim International GmbH | Stabilized pharmaceutical formulations of a potent hcv inhibitor |
| WO2013137869A1 (en) | 2012-03-14 | 2013-09-19 | Boehringer Ingelheim International Gmbh | Combination therapy for treating hcv infection in an hcv-hiv coinfected patient population |
| WO2013147749A1 (en) | 2012-03-27 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Oral combination therapy for treating hcv infection in specific patient subgenotype populations |
| WO2013147750A1 (en) | 2012-03-27 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Oral combination therapy for treating hcv infection in specific patient sub-population |
| WO2013143581A1 (en) | 2012-03-28 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Combination therapy for treating hcv infection in specific patient subgenotype sub-population |
| WO2014062196A1 (en) | 2012-10-19 | 2014-04-24 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9334279B2 (en) | 2012-11-02 | 2016-05-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EP2914613B1 (en) | 2012-11-02 | 2017-11-22 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| EP2914614B1 (en) | 2012-11-05 | 2017-08-16 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| CN105164148A (zh) | 2013-03-07 | 2015-12-16 | 百时美施贵宝公司 | 丙型肝炎病毒抑制剂 |
| WO2014138374A1 (en) | 2013-03-08 | 2014-09-12 | Boehringer Ingelheim International Gmbh | Oral combination therapy for treating hcv infection in specific patient sub-population |
| US9732076B2 (en) * | 2013-03-15 | 2017-08-15 | Boehringer Ingelheim International Gmbh | Solid oral dosage formulation of HCV inhibitor in the amorphous state |
| EP2899207A1 (en) | 2014-01-28 | 2015-07-29 | Amikana.Biologics | New method for testing HCV protease inhibition |
| EP3448392A4 (en) | 2016-04-28 | 2020-01-15 | Emory University | ALKYNOUS THERAPEUTIC NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND RELATED APPLICATIONS |
| AU2020261431A1 (en) | 2019-04-24 | 2021-12-09 | Regeneron Pharmaceuticals, Inc. | Methods of diagnosis and treatment of rheumatoid arthritis |
| JP2022534794A (ja) | 2019-06-04 | 2022-08-03 | サノフィ・バイオテクノロジー | 関節リウマチを有する対象における疼痛を治療するための組成物および方法 |
| CA3140164A1 (en) | 2020-04-05 | 2021-10-14 | Pfizer Inc. | Compounds and methods for the treatment of covid-19 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2907460A1 (de) | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
| US5342625A (en) | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
| IL102236A0 (en) | 1991-06-27 | 1993-01-14 | Ltt Inst Co Ltd | Topical preparations containing cyclosporin |
| US5329976A (en) | 1991-12-09 | 1994-07-19 | Habley Medical Technology Corporation | Syringe-filling and medication mixing dispenser |
| GB9208712D0 (en) | 1992-04-22 | 1992-06-10 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporin derivates |
| ATE198041T1 (de) | 1993-09-28 | 2000-12-15 | Scherer Gmbh R P | Herstellung von weichgelatinekapseln |
| JPH11505257A (ja) | 1995-05-19 | 1999-05-18 | アボツト・ラボラトリーズ | 親油性薬物の自己乳化性製剤 |
| US5993858A (en) | 1996-06-14 | 1999-11-30 | Port Systems L.L.C. | Method and formulation for increasing the bioavailability of poorly water-soluble drugs |
| EP0989851B1 (en) * | 1997-07-29 | 2002-10-02 | PHARMACIA & UPJOHN COMPANY | Self-emulsifying formulation for acidic lipophilic compounds |
| ES2174462T3 (es) | 1997-07-29 | 2002-11-01 | Upjohn Co | Formulacion autoestimulante para compuestos lipofilos. |
| NZ502569A (en) * | 1997-07-29 | 2002-05-31 | Upjohn Co | Self-emulsifying formulation for lipophilic compounds comprising a mixture of diglyceride and monoglyceride in a ratio of 9:1 to 6:4 |
| US6323180B1 (en) | 1998-08-10 | 2001-11-27 | Boehringer Ingelheim (Canada) Ltd | Hepatitis C inhibitor tri-peptides |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6652880B1 (en) | 1999-04-01 | 2003-11-25 | R.P. Scherer Technologies, Inc. | Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants |
| SE0000773D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
| GB0008785D0 (en) | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
| CA2466851C (en) | 2001-11-26 | 2012-09-11 | Supergen, Inc. | Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions |
| US6828301B2 (en) * | 2002-02-07 | 2004-12-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for hepatitis C viral protease inhibitors |
| CZ294371B6 (cs) | 2002-06-10 | 2004-12-15 | Pliva - Lachema, A. S. | Stabilizovaná farmaceutická kompozice na bázi polyoxyethylovaného ricinového oleje a způsob její přípravy |
| US20040033959A1 (en) * | 2002-07-19 | 2004-02-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical compositions for hepatitis C viral protease inhibitors |
| US20050075279A1 (en) | 2002-10-25 | 2005-04-07 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis C virus |
| UY28240A1 (es) | 2003-03-27 | 2004-11-08 | Boehringer Ingelheim Pharma | Fases cristalinas de un potente inhibidor de la hcv |
| WO2004093915A1 (en) | 2003-04-02 | 2004-11-04 | Boehringer Ingelheim International, Gmbh | Pharmaceutical compositions for hepatitis c viral protease inhibitors |
| WO2004103996A1 (en) * | 2003-05-21 | 2004-12-02 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor compounds |
| MXPA06003141A (es) | 2003-09-22 | 2006-06-05 | Boehringer Ingelheim Int | Peptidos macrociclicos activos contra el virus de la hepatitis c. |
| DE602005019700D1 (de) | 2004-03-15 | 2010-04-15 | Boehringer Ingelheim Int | E, die sich für die behandlung von hepatitis-c-virusinfektionen eignen |
| GEP20104926B (en) | 2004-03-30 | 2010-03-25 | Intermune Inc | Macrocyclic compounds as inhibitors of viral replication |
| JP5156374B2 (ja) * | 2004-05-25 | 2013-03-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 非環式hcvプロテアーゼインヒビターの調製方法 |
| WO2006130552A2 (en) | 2005-06-02 | 2006-12-07 | Schering Corporation | Methods of treating hepatitis c virus |
| US8003659B2 (en) | 2008-02-04 | 2011-08-23 | Indenix Pharmaceuticals, Inc. | Macrocyclic serine protease inhibitors |
| EP2687526A1 (en) | 2008-09-16 | 2014-01-22 | Boehringer Ingelheim International Gmbh | Crystalline forms of a 2-thiazolyl- 4-quinolinyl-oxy derivative, a potent HCV inhibitor |
| EA022272B1 (ru) | 2008-11-21 | 2015-12-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Фармацевтическая композиция эффективного ингибитора всг для перорального введения |
| PL2451438T3 (pl) | 2009-07-07 | 2014-07-31 | Boehringer Ingelheim Int | Kompozycja farmaceutyczna inhibitora proteazy wirusowego zapalenia wątroby typu C |
-
2010
- 2010-07-01 PL PL10731685T patent/PL2451438T3/pl unknown
- 2010-07-01 SI SI201030565T patent/SI2451438T1/sl unknown
- 2010-07-01 KR KR1020127000354A patent/KR101685941B1/ko not_active Expired - Fee Related
- 2010-07-01 MX MX2011013824A patent/MX2011013824A/es active IP Right Grant
- 2010-07-01 RS RS20140116A patent/RS53209B/sr unknown
- 2010-07-01 EP EP10731685.3A patent/EP2451438B8/en active Active
- 2010-07-01 SG SG2012001368A patent/SG177569A1/en unknown
- 2010-07-01 DK DK10731685.3T patent/DK2451438T3/da active
- 2010-07-01 ME MEP-2014-23A patent/ME01718B/me unknown
- 2010-07-01 HR HRP20140445AT patent/HRP20140445T1/hr unknown
- 2010-07-01 BR BR112012000287A patent/BR112012000287B8/pt not_active IP Right Cessation
- 2010-07-01 CN CN201080030433.1A patent/CN102470103B/zh not_active Expired - Fee Related
- 2010-07-01 AU AU2010270783A patent/AU2010270783B2/en not_active Ceased
- 2010-07-01 MA MA34511A patent/MA33491B1/fr unknown
- 2010-07-01 MY MYPI2012000028A patent/MY154683A/en unknown
- 2010-07-01 ES ES10731685.3T patent/ES2464367T3/es active Active
- 2010-07-01 CA CA2767692A patent/CA2767692C/en not_active Expired - Fee Related
- 2010-07-01 UA UAA201201066A patent/UA104195C2/ru unknown
- 2010-07-01 PE PE2011002086A patent/PE20120322A1/es active IP Right Grant
- 2010-07-01 AP AP2011005979A patent/AP2011005979A0/xx unknown
- 2010-07-01 GE GEAP201012562A patent/GEP20146016B/en unknown
- 2010-07-01 NZ NZ596928A patent/NZ596928A/xx not_active IP Right Cessation
- 2010-07-01 WO PCT/US2010/040734 patent/WO2011005646A2/en not_active Ceased
- 2010-07-01 JP JP2012519597A patent/JP5607736B2/ja not_active Expired - Fee Related
- 2010-07-01 PT PT107316853T patent/PT2451438E/pt unknown
- 2010-07-01 EA EA201200096A patent/EA023433B1/ru not_active IP Right Cessation
- 2010-07-05 UY UY0001032760A patent/UY32760A/es not_active Application Discontinuation
- 2010-07-06 TW TW099122196A patent/TWI490216B/zh not_active IP Right Cessation
- 2010-07-06 US US12/830,771 patent/US9034831B2/en active Active
- 2010-07-06 AR ARP100102427A patent/AR077393A1/es not_active Application Discontinuation
-
2011
- 2011-11-02 IL IL216098A patent/IL216098A/en active IP Right Grant
- 2011-12-29 CO CO11181070A patent/CO6480980A2/es not_active Application Discontinuation
-
2012
- 2012-01-05 TN TNP2012000009A patent/TN2012000009A1/en unknown
- 2012-01-06 CL CL2012000054A patent/CL2012000054A1/es unknown
- 2012-01-26 EC EC2012011624A patent/ECSP12011624A/es unknown
Also Published As
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