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SI2152868T1 - Sestavki prokariotske fenilalanin amonijakove liaze in postopki za uporabo navedenih sestavkov - Google Patents

Sestavki prokariotske fenilalanin amonijakove liaze in postopki za uporabo navedenih sestavkov

Info

Publication number
SI2152868T1
SI2152868T1 SI200831540T SI200831540T SI2152868T1 SI 2152868 T1 SI2152868 T1 SI 2152868T1 SI 200831540 T SI200831540 T SI 200831540T SI 200831540 T SI200831540 T SI 200831540T SI 2152868 T1 SI2152868 T1 SI 2152868T1
Authority
SI
Slovenia
Prior art keywords
compositions
lyase
methods
phenylalanine ammonia
prokaryotic phenylalanine
Prior art date
Application number
SI200831540T
Other languages
English (en)
Inventor
Michel C. Vellard
Paul A. Fitzpatrick
Emil D. Kakkis
Daniel J. Wendt
Original Assignee
Biomarin Pharmaceutical Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2152868(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharmaceutical Inc. filed Critical Biomarin Pharmaceutical Inc.
Publication of SI2152868T1 publication Critical patent/SI2152868T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI200831540T 2007-05-25 2008-05-23 Sestavki prokariotske fenilalanin amonijakove liaze in postopki za uporabo navedenih sestavkov SI2152868T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
PCT/US2008/006661 WO2008153776A1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions
EP08754717.0A EP2152868B1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

Publications (1)

Publication Number Publication Date
SI2152868T1 true SI2152868T1 (sl) 2015-12-31

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831540T SI2152868T1 (sl) 2007-05-25 2008-05-23 Sestavki prokariotske fenilalanin amonijakove liaze in postopki za uporabo navedenih sestavkov

Country Status (29)

Country Link
US (1) US7534595B2 (sl)
EP (2) EP2657335A1 (sl)
JP (1) JP5670183B2 (sl)
KR (2) KR20150038753A (sl)
CN (1) CN101842482B (sl)
AR (2) AR066716A1 (sl)
AU (1) AU2008263190B2 (sl)
BR (1) BRPI0811267B8 (sl)
CA (1) CA2687450C (sl)
CL (1) CL2008001497A1 (sl)
CY (2) CY1116894T1 (sl)
DK (1) DK2152868T3 (sl)
EA (1) EA018443B1 (sl)
ES (1) ES2551315T3 (sl)
HR (1) HRP20151268T1 (sl)
HU (2) HUE025784T2 (sl)
IL (1) IL202132A (sl)
LT (1) LTC2152868I2 (sl)
LU (1) LUC00133I2 (sl)
MX (1) MX2009012453A (sl)
MY (1) MY151413A (sl)
NL (1) NL301011I2 (sl)
NO (1) NO2019037I1 (sl)
PE (1) PE20090315A1 (sl)
PL (1) PL2152868T3 (sl)
PT (1) PT2152868E (sl)
SI (1) SI2152868T1 (sl)
TW (1) TWI418633B (sl)
WO (1) WO2008153776A1 (sl)

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US7537923B2 (en) 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
US20110201022A1 (en) * 2008-07-30 2011-08-18 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
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CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
WO2019217513A2 (en) 2018-05-09 2019-11-14 Biomarin Pharmaceutical Inc. Methods of treating phenylketonuria
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CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
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JP2023539632A (ja) 2020-08-28 2023-09-15 コデクシス, インコーポレイテッド 操作されたプロテアーゼバリアント
US11918633B2 (en) * 2021-05-19 2024-03-05 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating adolescent subjects
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
WO2023044381A1 (en) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN118931888A (zh) * 2023-05-09 2024-11-12 重庆派金生物科技有限公司 苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
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Also Published As

Publication number Publication date
NL301011I1 (nl) 2019-10-16
CL2008001497A1 (es) 2009-01-09
ES2551315T3 (es) 2015-11-18
TWI418633B (zh) 2013-12-11
CY2019039I2 (el) 2020-05-29
HRP20151268T1 (hr) 2015-12-18
CY1116894T1 (el) 2017-04-05
CN101842482B (zh) 2014-10-22
KR20150038753A (ko) 2015-04-08
AU2008263190A1 (en) 2008-12-18
TW200902052A (en) 2009-01-16
NO2019037I1 (no) 2019-10-16
IL202132A (en) 2017-06-29
IL202132A0 (en) 2010-06-16
MY151413A (en) 2014-05-30
CY2019039I1 (el) 2020-05-29
BRPI0811267B1 (pt) 2020-11-10
KR20100024437A (ko) 2010-03-05
MX2009012453A (es) 2010-01-25
EP2152868A1 (en) 2010-02-17
JP2010529835A (ja) 2010-09-02
EA200970980A1 (ru) 2010-04-30
WO2008153776A8 (en) 2009-07-30
LUC00133I2 (sl) 2020-07-16
EA018443B1 (ru) 2013-08-30
CA2687450C (en) 2019-03-26
DK2152868T3 (en) 2015-11-16
HUE025784T2 (en) 2016-05-30
CN101842482A (zh) 2010-09-22
LTPA2019517I1 (lt) 2019-10-25
HUS1900049I1 (hu) 2019-11-28
JP5670183B2 (ja) 2015-02-18
LUC00133I1 (sl) 2019-10-16
EP2152868B1 (en) 2015-09-02
US20080008695A1 (en) 2008-01-10
PL2152868T3 (pl) 2016-01-29
BRPI0811267A2 (pt) 2014-10-07
NL301011I2 (nl) 2020-05-13
CA2687450A1 (en) 2008-12-18
BRPI0811267B8 (pt) 2021-05-25
PT2152868E (pt) 2015-11-13
WO2008153776A1 (en) 2008-12-18
US7534595B2 (en) 2009-05-19
AU2008263190B2 (en) 2014-04-17
EP2657335A1 (en) 2013-10-30
AR066716A1 (es) 2009-09-09
KR101603796B1 (ko) 2016-03-17
AR110834A2 (es) 2019-05-08
PE20090315A1 (es) 2009-03-19
HK1135141A1 (zh) 2010-05-28
LTC2152868I2 (lt) 2020-09-25

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