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NO2019037I1 - pegvaliase - Google Patents

pegvaliase

Info

Publication number
NO2019037I1
NO2019037I1 NO2019037C NO2019037C NO2019037I1 NO 2019037 I1 NO2019037 I1 NO 2019037I1 NO 2019037 C NO2019037 C NO 2019037C NO 2019037 C NO2019037 C NO 2019037C NO 2019037 I1 NO2019037 I1 NO 2019037I1
Authority
NO
Norway
Prior art keywords
pegvaliase
Prior art date
Application number
NO2019037C
Other languages
English (en)
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2019037(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of NO2019037I1 publication Critical patent/NO2019037I1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO2019037C 2007-05-25 2019-10-16 pegvaliase NO2019037I1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
PCT/US2008/006661 WO2008153776A1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

Publications (1)

Publication Number Publication Date
NO2019037I1 true NO2019037I1 (no) 2019-10-16

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2019037C NO2019037I1 (no) 2007-05-25 2019-10-16 pegvaliase

Country Status (29)

Country Link
US (1) US7534595B2 (no)
EP (2) EP2657335A1 (no)
JP (1) JP5670183B2 (no)
KR (2) KR20150038753A (no)
CN (1) CN101842482B (no)
AR (2) AR066716A1 (no)
AU (1) AU2008263190B2 (no)
BR (1) BRPI0811267B8 (no)
CA (1) CA2687450C (no)
CL (1) CL2008001497A1 (no)
CY (2) CY1116894T1 (no)
DK (1) DK2152868T3 (no)
EA (1) EA018443B1 (no)
ES (1) ES2551315T3 (no)
HR (1) HRP20151268T1 (no)
HU (2) HUE025784T2 (no)
IL (1) IL202132A (no)
LT (1) LTC2152868I2 (no)
LU (1) LUC00133I2 (no)
MX (1) MX2009012453A (no)
MY (1) MY151413A (no)
NL (1) NL301011I2 (no)
NO (1) NO2019037I1 (no)
PE (1) PE20090315A1 (no)
PL (1) PL2152868T3 (no)
PT (1) PT2152868E (no)
SI (1) SI2152868T1 (no)
TW (1) TWI418633B (no)
WO (1) WO2008153776A1 (no)

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US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7537923B2 (en) 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
US20110201022A1 (en) * 2008-07-30 2011-08-18 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
SI3025728T1 (sl) * 2010-02-04 2018-11-30 Biomarin Pharmaceutical Inc. Metoda za čiščenje prokariontskih fenilalanin amonij-liaznih variant
EP3222288A1 (en) * 2012-07-27 2017-09-27 University of North Texas Genetically modified probiotic for the treatment of phenylketonuria (pku) disease
ES2890955T3 (es) 2013-04-18 2022-01-25 Codexis Inc Polipéptidos de fenilalanina amoníaco liasa modificados
BR112016011195A2 (pt) * 2013-11-18 2017-09-19 Rubius Therapeutics Inc Células eritroides enucleadas e seus métodos de fabricação, composição farmacêutica e seu uso, uso de uma população de células eritroides, biorreator, mistura de células e dispositivo médico
US10869898B2 (en) 2014-04-01 2020-12-22 Rubius Therapeutics, Inc. Methods and compositions for immunomodulation
CA2943432A1 (en) 2014-04-16 2015-10-22 Codexis, Inc. Engineered tyrosine ammonia lyase
AU2015370125B2 (en) 2014-12-22 2022-02-03 Codexis, Inc. Human alpha-galactosidase variants
TW202440903A (zh) * 2015-08-04 2024-10-16 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法（一）
MX2019000962A (es) 2016-07-26 2019-08-01 Biomarin Pharm Inc Novedosas proteinas de la capside del virus adenoasociado.
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CN106497905A (zh) * 2016-12-14 2017-03-15 江南大学 一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
KR102573324B1 (ko) * 2017-02-13 2023-08-30 코덱시스, 인코포레이티드 조작된 페닐알라닌 암모니아 리아제 폴리펩티드
CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
WO2019217513A2 (en) 2018-05-09 2019-11-14 Biomarin Pharmaceutical Inc. Methods of treating phenylketonuria
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
EP3807409A4 (en) * 2018-06-12 2022-08-03 Codexis, Inc. Engineered tyrosine ammonia lyase
US11198861B2 (en) * 2018-07-12 2021-12-14 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
JP2022513199A (ja) 2018-12-14 2022-02-07 コデクシス， インコーポレイテッド 操作されたチロシンアンモニアリアーゼ
JP2022515742A (ja) 2018-12-20 2022-02-22 コデクシス， インコーポレイテッド α－ガラクトシダーゼバリアント
CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
JP7699107B2 (ja) 2019-08-30 2025-06-26 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 操作されたリパーゼ改変体
KR20220129547A (ko) 2019-12-20 2022-09-23 코덱시스, 인코포레이티드 조작된 산성 알파-글루코시다제 변이체
BR112022015139A2 (pt) 2020-02-04 2022-10-11 Codexis Inc Polipeptídeo da leucina descarboxilase engenheirada, composição, sequência de polinucleotídeo engenheirado, vetor de expressão, célula hospedeira, métodos para produzir um polipeptídeo da leucina descarboxilase engenheirada e para tratar e/ou prevenir os sintomas de doença da urina de xarope de bordo, composição, e, uso
WO2021168060A1 (en) * 2020-02-19 2021-08-26 Trustees Of Tufts College Methods for engineering amino acid ammonia lyase enzymes and enzymes thereby obtained
AR122409A1 (es) 2020-04-03 2022-09-07 Biomarin Pharm Inc Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
CA3191900A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered amylase variants
JP2023539632A (ja) 2020-08-28 2023-09-15 コデクシス， インコーポレイテッド 操作されたプロテアーゼバリアント
US11918633B2 (en) * 2021-05-19 2024-03-05 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating adolescent subjects
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
WO2023044381A1 (en) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN118931888A (zh) * 2023-05-09 2024-11-12 重庆派金生物科技有限公司 苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
GB202307239D0 (en) 2023-05-15 2023-06-28 Evox Therapeutics Ltd Gene therapies for Phenylketonuria
CN116478975B (zh) * 2023-06-16 2023-09-01 苏州优信合生技术有限公司 高活性苯丙氨酸解氨酶突变体及其表达菌株
US20250161466A1 (en) 2023-11-17 2025-05-22 Biomarin Pharmaceutical Inc. Conjugates of phenylalanine ammonia-lyase and poegma and methods for their use

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Also Published As

Publication number Publication date
NL301011I1 (nl) 2019-10-16
CL2008001497A1 (es) 2009-01-09
ES2551315T3 (es) 2015-11-18
TWI418633B (zh) 2013-12-11
CY2019039I2 (el) 2020-05-29
HRP20151268T1 (hr) 2015-12-18
CY1116894T1 (el) 2017-04-05
CN101842482B (zh) 2014-10-22
KR20150038753A (ko) 2015-04-08
AU2008263190A1 (en) 2008-12-18
TW200902052A (en) 2009-01-16
IL202132A (en) 2017-06-29
IL202132A0 (en) 2010-06-16
MY151413A (en) 2014-05-30
CY2019039I1 (el) 2020-05-29
BRPI0811267B1 (pt) 2020-11-10
KR20100024437A (ko) 2010-03-05
MX2009012453A (es) 2010-01-25
EP2152868A1 (en) 2010-02-17
JP2010529835A (ja) 2010-09-02
EA200970980A1 (ru) 2010-04-30
WO2008153776A8 (en) 2009-07-30
LUC00133I2 (no) 2020-07-16
EA018443B1 (ru) 2013-08-30
CA2687450C (en) 2019-03-26
DK2152868T3 (en) 2015-11-16
HUE025784T2 (en) 2016-05-30
CN101842482A (zh) 2010-09-22
LTPA2019517I1 (lt) 2019-10-25
HUS1900049I1 (hu) 2019-11-28
JP5670183B2 (ja) 2015-02-18
LUC00133I1 (no) 2019-10-16
EP2152868B1 (en) 2015-09-02
US20080008695A1 (en) 2008-01-10
PL2152868T3 (pl) 2016-01-29
BRPI0811267A2 (pt) 2014-10-07
NL301011I2 (nl) 2020-05-13
CA2687450A1 (en) 2008-12-18
BRPI0811267B8 (pt) 2021-05-25
PT2152868E (pt) 2015-11-13
WO2008153776A1 (en) 2008-12-18
US7534595B2 (en) 2009-05-19
AU2008263190B2 (en) 2014-04-17
EP2657335A1 (en) 2013-10-30
AR066716A1 (es) 2009-09-09
SI2152868T1 (sl) 2015-12-31
KR101603796B1 (ko) 2016-03-17
AR110834A2 (es) 2019-05-08
PE20090315A1 (es) 2009-03-19
HK1135141A1 (zh) 2010-05-28
LTC2152868I2 (lt) 2020-09-25

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