[go: up one dir, main page]

SI2061803T1 - Postopek za čiščenje proteinov, ki vsebujejo FC - Google Patents

Postopek za čiščenje proteinov, ki vsebujejo FC

Info

Publication number
SI2061803T1
SI2061803T1 SI200732135T SI200732135T SI2061803T1 SI 2061803 T1 SI2061803 T1 SI 2061803T1 SI 200732135 T SI200732135 T SI 200732135T SI 200732135 T SI200732135 T SI 200732135T SI 2061803 T1 SI2061803 T1 SI 2061803T1
Authority
SI
Slovenia
Prior art keywords
purification
containing proteins
proteins
Prior art date
Application number
SI200732135T
Other languages
English (en)
Other versions
SI2061803T2 (sl
Inventor
Alex Eon-Duval
Alain Lamproye
Original Assignee
Ares Trading S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38610939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2061803(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ares Trading S.A. filed Critical Ares Trading S.A.
Publication of SI2061803T1 publication Critical patent/SI2061803T1/sl
Publication of SI2061803T2 publication Critical patent/SI2061803T2/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI200732135T 2006-08-28 2007-08-27 Postopek za čiščenje proteinov, ki vsebujejo FC SI2061803T2 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06119611 2006-08-28
US84254206P 2006-09-06 2006-09-06
PCT/EP2007/058887 WO2008025748A1 (en) 2006-08-28 2007-08-27 Process for the purification of fc-containing proteins
EP07802925.3A EP2061803B2 (en) 2006-08-28 2007-08-27 Process for the purification of fc-containing proteins

Publications (2)

Publication Number Publication Date
SI2061803T1 true SI2061803T1 (sl) 2019-12-31
SI2061803T2 SI2061803T2 (sl) 2023-01-31

Family

ID=38610939

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200732135T SI2061803T2 (sl) 2006-08-28 2007-08-27 Postopek za čiščenje proteinov, ki vsebujejo FC

Country Status (20)

Country Link
US (1) US8513393B2 (sl)
EP (1) EP2061803B2 (sl)
JP (1) JP2010501623A (sl)
KR (1) KR101770312B1 (sl)
AR (1) AR062570A1 (sl)
AU (1) AU2007291283B2 (sl)
CA (1) CA2661748C (sl)
DK (1) DK2061803T4 (sl)
EA (1) EA017152B1 (sl)
ES (1) ES2755386T5 (sl)
FI (1) FI2061803T4 (sl)
HU (1) HUE045898T2 (sl)
IL (1) IL197220A (sl)
LT (1) LT2061803T (sl)
MX (1) MX2009002014A (sl)
PL (1) PL2061803T5 (sl)
PT (1) PT2061803T (sl)
SI (1) SI2061803T2 (sl)
UA (1) UA99262C2 (sl)
WO (1) WO2008025748A1 (sl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5096369B2 (ja) 2005-12-20 2012-12-12 ブリストル−マイヤーズ スクイブ カンパニー 組成物および組成物の製造方法
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
JP2010501623A (ja) † 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Ｆｃ含有タンパク質の精製法
US20090148435A1 (en) * 2007-10-30 2009-06-11 Genentech, Inc. Antibody purification by cation exchange chromatography
CN105111309A (zh) * 2008-10-20 2015-12-02 Abbvie公司 使用a蛋白亲和层析分离和纯化抗体
CN104974251A (zh) * 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
CN102257004A (zh) * 2008-10-20 2011-11-23 雅培制药有限公司 与il-12结合的抗体及其纯化方法
MX2011004199A (es) * 2008-10-20 2011-05-24 Abbott Lab Anticuerpos que unen a il-18 y metodos para purificar los mismos.
WO2011017514A1 (en) 2009-08-07 2011-02-10 Millipore Corporation Methods for purifying a target protein from one or more impurities in a sample
ES2982297T3 (es) 2009-12-18 2024-10-15 Novartis Ag Método de cromatografía de afinidad
CA2787009C (en) 2010-01-15 2018-04-03 Bio-Rad Laboratories, Inc. Surface neutralization of apatite
US8895707B2 (en) * 2010-08-18 2014-11-25 Bio-Rad Laboratories, Inc. Elution of proteins from hydroxyapatite resins without resin deterioration
JP5798307B2 (ja) * 2010-09-03 2015-10-21 国立大学法人名古屋大学 グロボトリアオシルセラミドを特異的に認識するモノクローナル抗体及びその作製法
EP2655412B1 (en) * 2010-12-21 2018-01-17 F. Hoffmann-La Roche AG Isoform enriched antibody preparation and method for obtaining it
US9592540B2 (en) 2011-02-02 2017-03-14 Bio-Rad Laboratories, Inc. Apatite surface neutralization with alkali solutions
KR102058254B1 (ko) 2011-03-29 2019-12-20 글락소스미스클라인 엘엘씨 단백질 정제용 완충제 시스템
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
CN104507952B (zh) 2012-05-30 2018-08-10 生物辐射实验室股份有限公司 基于磷灰石的色谱树脂的原位恢复
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
CN106536565A (zh) * 2014-06-13 2017-03-22 鲁宾有限公司 一种用于纯化TNFR‑Fc融合蛋白的方法
US10092857B2 (en) 2014-06-23 2018-10-09 Bio-Rad Laboratories, Inc. Apatite in-situ restoration
WO2015200282A1 (en) 2014-06-23 2015-12-30 Bio-Rad Laboratories, Inc. Apatite pretreatment
EP2975050B1 (en) * 2014-07-18 2019-05-29 Sandoz Ag Quantification of misfolded TNFR2:Fc
AU2016233557B2 (en) * 2015-03-13 2021-06-24 Bristol-Myers Squibb Company Use of alkaline washes during chromatography to remove impurities
PE20230494A1 (es) 2020-05-08 2023-03-23 Alpine Immune Sciences Inc Proteinas inmunomoduladoras inhibidoras de april y baff y metodos de uso de las mismas

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU630497B2 (en) 1989-09-05 1992-10-29 Immunex Corporation Tumor necrosis factor-alpha and -beta receptors
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
KR100232688B1 (ko) 1992-09-15 1999-12-01 스코트 쥐. 홀퀴스트 종양 괴사 인자 길항제를 함유하는 tnf-의존성 염증 치료용 제약 조성물
DE59309332D1 (de) * 1993-12-27 1999-03-04 Rotkreuzstiftung Zentratrallab Verfahren zur Herstellung eines Konzentrates von Anti-D-Immunoglobulin G und pharmazeutische Zusammensetzung, die dieses enthält
US6406901B1 (en) 1995-06-08 2002-06-18 Immunex Corporation TNF-a converting enzyme
ES2227598T3 (es) * 1995-06-08 2005-04-01 Immunex Corporation Enzima conversiva de tnf-alfa.
US5969102A (en) 1997-03-03 1999-10-19 St. Jude Children's Research Hospital Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
IL121900A (en) 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
KR100960211B1 (ko) * 1998-05-06 2010-05-27 제넨테크, 인크. 이온 교환 크로마토그래피에 의한 단백질 정제 방법
IL139609A (en) 1998-06-01 2006-06-11 Genentech Inc Separation of polypeptides monomers
DK1084147T3 (da) 1998-06-09 2004-10-25 Statens Seruminstitut Fremgangsmåde til fremstilling af immunglobuliner til administration og andre immunglobulinprodukter
PT1642972E (pt) 1999-01-07 2010-04-07 Zymogenetics Inc Utilizações terapêuticas de receptores solúveis br43x2
DE19955558C2 (de) 1999-11-18 2003-03-20 Stefan Kochanek Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren
WO2001087977A2 (en) 2000-05-12 2001-11-22 Amgen Inc. Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci
PL403488A1 (pl) * 2001-05-24 2013-07-08 Zymogenetics, Inc. Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
PL222211B1 (pl) 2001-06-26 2016-07-29 Amgen Fremont Inc Przeciwciało przeciwko OPGL, kompozycja je zawierająca, jego zastosowanie i sposób jego wytwarzania, sposób wykrywania poziomu OPGL, kompozycja obejmująca polinukleotydy i komórka gosodarza
PL374311A1 (en) 2001-12-21 2005-10-03 Immunex Corporation Methods for purifying protein
JP4319979B2 (ja) 2002-04-26 2009-08-26 ジェネンテック・インコーポレーテッド タンパク質の非アフィニティ精製
JP5303092B2 (ja) 2002-09-11 2013-10-02 ジェネンテック， インコーポレイテッド タンパク質精製
KR101119448B1 (ko) 2002-09-11 2012-03-15 추가이 세이야쿠 가부시키가이샤 단백질 정제 방법
DK1601697T3 (da) * 2003-02-28 2007-10-01 Lonza Biologics Plc Oprensning af antistof ved protein A- og ionbytningskromatografi
US20060257972A1 (en) 2003-03-31 2006-11-16 Takashi Ishihara Purification of human monoclonal antibody and human polyclonal antibody
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
EP1678208B1 (en) 2003-10-27 2013-05-15 Wyeth LLC Removal of high molecular weight aggregates using hydroxyapatite chromatography
ES2438098T3 (es) * 2003-11-13 2014-01-15 Hanmi Science Co., Ltd. Composición farmacéutica que comprende un Fc de inmunoglobulina como vehículo
MXPA06009496A (es) * 2004-04-14 2007-04-09 Hoffmann La Roche Proteina de fusion interleukina-15/fc purificada y preparacion de la misma.
MX2007011129A (es) 2005-03-11 2007-11-06 Wyeth Corp Un metodo de cromatografia de particion debil.
EP1869067A1 (en) * 2005-04-11 2007-12-26 Medarex, Inc. Protein purification using hcic amd ion exchange chromatography
CA2611815A1 (en) * 2005-06-17 2006-12-28 Elan Pharma International Limited Methods of purifying anti a beta antibodies
JP2010510963A (ja) 2006-06-14 2010-04-08 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー セラミックヒドロキシアパタイトを使用する抗体の精製方法
JP2010501623A (ja) † 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Ｆｃ含有タンパク質の精製法
AU2008206923A1 (en) * 2007-01-17 2008-07-24 Merck Serono S.A. Process for the purification of Fc-containing proteins

Also Published As

Publication number Publication date
PL2061803T5 (pl) 2023-03-27
KR101770312B1 (ko) 2017-08-22
EP2061803A1 (en) 2009-05-27
PT2061803T (pt) 2019-11-21
EA200970231A1 (ru) 2009-08-28
KR20090057296A (ko) 2009-06-04
UA99262C2 (uk) 2012-08-10
EP2061803B2 (en) 2022-11-16
AR062570A1 (es) 2008-11-19
EP2061803B1 (en) 2019-08-14
US8513393B2 (en) 2013-08-20
ES2755386T3 (es) 2020-04-22
DK2061803T4 (da) 2022-12-05
DK2061803T3 (da) 2019-11-18
LT2061803T (lt) 2019-11-25
MX2009002014A (es) 2009-03-09
AU2007291283A1 (en) 2008-03-06
CA2661748A1 (en) 2008-03-06
EA017152B1 (ru) 2012-10-30
IL197220A0 (en) 2009-12-24
ES2755386T5 (es) 2023-04-05
JP2010501623A (ja) 2010-01-21
CA2661748C (en) 2016-02-09
AU2007291283B2 (en) 2012-09-20
IL197220A (en) 2013-06-27
WO2008025748A1 (en) 2008-03-06
HK1131400A1 (en) 2010-01-22
PL2061803T3 (pl) 2020-02-28
HUE045898T2 (hu) 2020-01-28
SI2061803T2 (sl) 2023-01-31
US20100190961A1 (en) 2010-07-29
FI2061803T4 (fi) 2023-03-14

Similar Documents

Publication Publication Date Title
LT2061803T (lt) Fc turinčių baltymų gryninimo būdas
IL199753A0 (en) Process for the purification of fc-containing proteins
ZA200900836B (en) Process for the purification of FC-fusion proteins
IL205107A0 (en) Method for purifying fc-fusion proteins
IL197765A0 (en) Methods for purification of polypeptide conjugates
IL187642A0 (en) METHODS FOR PURIFYING PROTEINS HAVING Fc REGIONS
ZA200708526B (en) Process for the removal of contaminants
PL1974806T3 (pl) Sposób oczyszczania wody
IL184184A0 (en) Process for the purification of duloxetine hydrochloride
PL2628746T3 (pl) Sposób zatężania polipeptydu
IL204949A0 (en) Method for purifying an fc- containing protein
ZA200900837B (en) Process for the purification of FC-containing proteins
IL184715A0 (en) Process for the preparation of intermediates
SI1960416T1 (sl) Proces čiščenja henodeoksiholinske kisline
ZA200607439B (en) Process for gas purification
GB0503942D0 (en) Purification process
GB0624227D0 (en) Protein purification
GB2432157B (en) Letrozole purification process
EP1899375A4 (en) NEW METHOD FOR THE PURIFICATION OF LACTOFERRIN
GB0604236D0 (en) Adsorbents for protein purification
PL1973563T3 (pl) Sposób oczyszczania alfa-1-antytrypsyny
GB0523257D0 (en) Purification process
ZA200708802B (en) An improved process for the purification of perindopril
SI1966228T1 (sl) Postopek čiščenja za henodeoksiholinsko kislino
PL2079758T3 (pl) Sposób oczyszczania DnaK