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SI2054363T1 - Asimetrično hidrogeniranje 1,1,1-trifluoroacetona - Google Patents

Asimetrično hidrogeniranje 1,1,1-trifluoroacetona

Info

Publication number
SI2054363T1
SI2054363T1 SI200731230T SI200731230T SI2054363T1 SI 2054363 T1 SI2054363 T1 SI 2054363T1 SI 200731230 T SI200731230 T SI 200731230T SI 200731230 T SI200731230 T SI 200731230T SI 2054363 T1 SI2054363 T1 SI 2054363T1
Authority
SI
Slovenia
Prior art keywords
trifluoroacetone
asymmetric hydrogenation
hydrogenation
asymmetric
Prior art date
Application number
SI200731230T
Other languages
English (en)
Inventor
Kurt Puentener
Pius Waldmeier
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2054363T1 publication Critical patent/SI2054363T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/34Halogenated alcohols
    • C07C31/38Halogenated alcohols containing only fluorine as halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200731230T 2006-07-27 2007-07-17 Asimetrično hidrogeniranje 1,1,1-trifluoroacetona SI2054363T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06117928 2006-07-27
EP07787638.1A EP2054363B1 (en) 2006-07-27 2007-07-17 Asymmetric hydrogenation of 1,1,1-trifluoroacetone
PCT/EP2007/057372 WO2008012240A1 (en) 2006-07-27 2007-07-17 Asymmetric hydrogenation of 1,1,1-trifluoroacetone

Publications (1)

Publication Number Publication Date
SI2054363T1 true SI2054363T1 (sl) 2013-06-28

Family

ID=38578449

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731230T SI2054363T1 (sl) 2006-07-27 2007-07-17 Asimetrično hidrogeniranje 1,1,1-trifluoroacetona

Country Status (15)

Country Link
US (1) US7504544B2 (sl)
EP (1) EP2054363B1 (sl)
JP (1) JP5345932B2 (sl)
KR (1) KR101087941B1 (sl)
CN (1) CN101500974B (sl)
AU (1) AU2007278274B2 (sl)
BR (1) BRPI0715096B1 (sl)
CA (1) CA2658773C (sl)
DK (1) DK2054363T3 (sl)
ES (1) ES2411713T3 (sl)
IL (1) IL196327A (sl)
MX (1) MX2009000616A (sl)
PL (1) PL2054363T3 (sl)
SI (1) SI2054363T1 (sl)
WO (1) WO2008012240A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101161603B1 (ko) 2007-09-06 2012-07-03 닛뽕소다 가부시키가이샤 광학 활성 3-퀴누클리디놀 유도체의 제조 방법
US8207379B2 (en) * 2008-04-07 2012-06-26 Nippon Soda Co., Ltd. Ruthenium compound and method for producing optically active aminoalcohol compound
ES2863542T3 (es) * 2009-03-17 2021-10-11 Johnson Matthey Plc Proceso para la hidrogenación de cetonas en presencia de catalizadores de Ru (II)
JP5656474B2 (ja) 2010-06-28 2015-01-21 関東化学株式会社 脂肪族光学活性フルオロアルコールの製造方法
CN104447205A (zh) * 2014-11-27 2015-03-25 广东东阳光药业有限公司 制备(s)-三氟异丙醇的方法
CN107815468B (zh) 2016-08-31 2021-03-16 百奥赛图(北京)医药科技股份有限公司 人源化基因改造动物模型的制备方法及应用
CA3166938A1 (en) 2020-01-09 2021-07-15 Disc Medicine, Inc. Methods of treating erythropoietic protoporphyria, x-linked protoporphyria, or congenital erythropoietic porphyria with glycine transport inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0398132T3 (da) 1989-05-18 1995-12-18 Hoffmann La Roche Phosphorforbindelser
US5302738A (en) * 1991-03-15 1994-04-12 Hoffmann-La Roche Inc. Chiral phosphines
US5256321A (en) 1992-07-10 1993-10-26 The Lubrizol Corporation Grease compositions
JP4674393B2 (ja) * 2000-06-21 2011-04-20 ダイキン工業株式会社 光学活性な含フッ素β−ヒドロキシエステルの製造方法
JP4286486B2 (ja) * 2001-01-15 2009-07-01 日本曹達株式会社 ルテニウム化合物、ジアミン配位子および光学活性アルコールの製造方法
FR2830254B1 (fr) * 2001-09-28 2004-09-17 Synkem Nouvelles diphosphines, leurs complexes avec des metaux de transition et leur utilisation en synthese asymetrique
JP4919562B2 (ja) * 2001-09-28 2012-04-18 日本曹達株式会社 ルテニウムヒドリド錯体、アルコール化合物の製造方法およびラセミ体カルボニル化合物の分割方法
CN1166672C (zh) * 2001-12-07 2004-09-15 中国科学院上海有机化学研究所 非c2对称轴手性双膦配体的金属络合物、合成方法及其在酮的不对称催化氢化中的应用
JP3566955B2 (ja) * 2001-12-28 2004-09-15 関東化学株式会社 新規ルテニウム錯体およびこれを触媒として用いるアルコール化合物の製造方法
WO2003061826A1 (en) * 2002-01-24 2003-07-31 Dsm Ip Assets B.V. Process for preparing nonracemic chiral alcohols
FR2849036B1 (fr) * 2002-12-18 2005-05-20 Rhodia Chimie Sa Diphosphines chirales, leur preparation et leurs utilisations comme ligands dans la synthese de complexes destines a la catalyse asymetrique
RS53252B (sr) 2003-08-11 2014-08-29 F.Hoffmann-La Roche Ag. Piperazin sa or-supstituisanom fenil grupom i njihova upotreba kao inhibitora glyt1
ATE509024T1 (de) * 2003-08-13 2011-05-15 Takasago Perfumery Co Ltd Neuer übergangsmetallkomplex und verfahren zur herstellung von optisch aktivem alkohol mit dem komplex
WO2007006650A2 (en) * 2005-07-08 2007-01-18 F. Hoffmann-La Roche Ag Asymmetric reduction of 1,1,1-trifluoroacetone

Also Published As

Publication number Publication date
US20080027249A1 (en) 2008-01-31
WO2008012240A1 (en) 2008-01-31
JP2009544653A (ja) 2009-12-17
IL196327A0 (en) 2009-09-22
IL196327A (en) 2011-12-29
PL2054363T3 (pl) 2013-09-30
CN101500974B (zh) 2013-03-20
EP2054363B1 (en) 2013-04-17
AU2007278274A1 (en) 2008-01-31
BRPI0715096B1 (pt) 2016-11-08
DK2054363T3 (da) 2013-06-03
EP2054363A1 (en) 2009-05-06
US7504544B2 (en) 2009-03-17
JP5345932B2 (ja) 2013-11-20
KR101087941B1 (ko) 2011-11-28
MX2009000616A (es) 2009-01-28
AU2007278274B2 (en) 2012-09-13
CN101500974A (zh) 2009-08-05
BRPI0715096A2 (pt) 2013-03-26
CA2658773A1 (en) 2008-01-31
ES2411713T3 (es) 2013-07-08
KR20090023505A (ko) 2009-03-04
CA2658773C (en) 2014-04-08

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