SI1556016T1 - Večplastne učinkovino vsebujoče zdravilne oblike, ki obsegajo nevtralno jedro ter notranjo in zunanjo prevleko iz metakrilatnih kopolimerov in metakrilatnih monomerov - Google Patents
Večplastne učinkovino vsebujoče zdravilne oblike, ki obsegajo nevtralno jedro ter notranjo in zunanjo prevleko iz metakrilatnih kopolimerov in metakrilatnih monomerovInfo
- Publication number
- SI1556016T1 SI1556016T1 SI200331452T SI200331452T SI1556016T1 SI 1556016 T1 SI1556016 T1 SI 1556016T1 SI 200331452 T SI200331452 T SI 200331452T SI 200331452 T SI200331452 T SI 200331452T SI 1556016 T1 SI1556016 T1 SI 1556016T1
- Authority
- SI
- Slovenia
- Prior art keywords
- coating consisting
- methacrylate
- outer coating
- dosage forms
- active substances
- Prior art date
Links
- 239000011248 coating agent Substances 0.000 title abstract 4
- 238000000576 coating method Methods 0.000 title abstract 4
- 229920001577 copolymer Polymers 0.000 title abstract 4
- 239000000178 monomer Substances 0.000 title abstract 3
- 230000007935 neutral effect Effects 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 title 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10250543A DE10250543A1 (de) | 2002-10-29 | 2002-10-29 | Mehrschichtige Arzneiform |
| PCT/EP2003/009800 WO2004039357A1 (de) | 2002-10-29 | 2003-09-04 | Mehrschichtige wirkstoffhaltige arzneiformen, die einen neutralen kern sowie einen inneren und äusseren überzug aus methacrylat-copolymeren und -monomeren umfassen |
| EP03809716A EP1556016B1 (de) | 2002-10-29 | 2003-09-04 | Mehrschichtige wirkstoffhaltige arzneiformen, die einen neutralen kern sowie einen inneren und äusseren überzug aus methacrylat-copolymeren und -monomeren umfassen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1556016T1 true SI1556016T1 (sl) | 2009-02-28 |
Family
ID=32114959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200331452T SI1556016T1 (sl) | 2002-10-29 | 2003-09-04 | Večplastne učinkovino vsebujoče zdravilne oblike, ki obsegajo nevtralno jedro ter notranjo in zunanjo prevleko iz metakrilatnih kopolimerov in metakrilatnih monomerov |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20060204576A1 (sl) |
| EP (1) | EP1556016B1 (sl) |
| JP (1) | JP4819362B2 (sl) |
| KR (1) | KR20050083847A (sl) |
| CN (1) | CN1688295B (sl) |
| AT (1) | ATE406876T1 (sl) |
| AU (1) | AU2003266351A1 (sl) |
| BR (1) | BRPI0315740B8 (sl) |
| CA (1) | CA2502371C (sl) |
| DE (2) | DE10250543A1 (sl) |
| ES (1) | ES2312853T3 (sl) |
| IL (1) | IL167334A (sl) |
| MX (1) | MXPA05004573A (sl) |
| PL (1) | PL206707B1 (sl) |
| SI (1) | SI1556016T1 (sl) |
| WO (1) | WO2004039357A1 (sl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| WO2005034923A1 (en) * | 2003-10-10 | 2005-04-21 | Ethypharm | Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these |
| DE10353196A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform mit einer die Abgabe einer modulatorischen Substanz beeinflussenden Matrix |
| DE10353186A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz |
| DE102004035936A1 (de) * | 2004-07-23 | 2006-03-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| DE102005007059A1 (de) * | 2005-02-15 | 2006-08-24 | Röhm GmbH & Co. KG | Teilneutralisiertes anionisches (Meth)acrylat-Copolymer |
| CA2607272A1 (en) * | 2005-05-09 | 2006-11-16 | Azur Pharma Limited | Formulations of mast cell stabilizing agents for delivery to the colon |
| EP1883396B1 (en) | 2005-05-18 | 2013-07-03 | DA Volterra | Colonic delivery of adsorbents |
| US8048413B2 (en) | 2006-05-17 | 2011-11-01 | Helene Huguet | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
| DE102007009243A1 (de) * | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets |
| EP2173329A1 (en) * | 2007-07-03 | 2010-04-14 | Synthon B.V. | Tolterodine bead |
| CN105534936B (zh) * | 2007-08-13 | 2020-07-31 | Ohemo 生命科学股份有限公司 | 抗滥用药物、使用方法和制备方法 |
| EP2230932B1 (en) | 2008-01-10 | 2017-03-29 | Evonik Röhm GmbH | Coated pharmaceutical or nutraceutical preparation with enhanced active substance release in the colon |
| US9011907B2 (en) * | 2008-01-10 | 2015-04-21 | Evonik Röhm Gmbh | Coated pharmaceutical or nutraceutical preparation with enhanced pulsed active substance release |
| CN101683323B (zh) * | 2008-09-24 | 2011-12-28 | 浙江医药股份有限公司新昌制药厂 | 含有万古霉素的结肠靶向微丸及其制备方法 |
| CN102164588B (zh) * | 2008-09-24 | 2015-07-08 | 赢创罗姆有限公司 | 耐受乙醇影响的pH依赖性受控释放的药物组合物 |
| JP5453434B2 (ja) | 2008-09-24 | 2014-03-26 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | エタノールの影響に対する耐性を有するオピオイドではないｐＨ依存の制御放出の医薬組成物 |
| US8945616B2 (en) * | 2009-02-17 | 2015-02-03 | Mylan Pharmaceuticals Inc. | Controlled release budesonide minitablets |
| US8945615B2 (en) * | 2009-02-17 | 2015-02-03 | Mylan Pharmaceuticals Inc. | Controlled release budesonide minitablets |
| EP2405982B1 (en) | 2009-03-09 | 2013-12-18 | Dow Corning Corporation | Methods for removing vicinal diols from lactic acid fermentation broth |
| HUE032817T2 (en) | 2009-03-18 | 2017-11-28 | Evonik Roehm Gmbh | Regulated release pharmaceutical composition comprising a coating containing neutral vinyl polymers and excipients and resistant to the influence of ethanol |
| CN102365083A (zh) * | 2009-03-18 | 2012-02-29 | 赢创罗姆有限公司 | 采用包含聚合物混合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物 |
| CN105287434A (zh) * | 2009-03-18 | 2016-02-03 | 赢创罗姆有限公司 | 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物 |
| EP2371356B1 (en) * | 2010-03-12 | 2012-12-19 | Phoeme GmbH | Multi-particle pharmaceutical formulation for colon absorption |
| WO2012171884A1 (en) | 2011-06-17 | 2012-12-20 | Evonik Röhm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
| US11229600B2 (en) * | 2014-09-24 | 2022-01-25 | Vital Beverages Global Inc. | Compositions and methods for selective GI tract delivery |
| CA2936740C (en) | 2014-10-31 | 2017-10-10 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| SI3302444T1 (sl) | 2015-06-05 | 2021-01-29 | Evonik Operations Gmbh | Farmacevtski ali nutracevtski sestavek z odpornostjo na vpliv etanola |
| US10744070B2 (en) | 2015-06-19 | 2020-08-18 | University Of Southern California | Enteral fast access tract platform system |
| CA2990230A1 (en) | 2015-06-19 | 2016-12-22 | University Of Southern California | Compositions and methods for modified nutrient delivery |
| US12472149B2 (en) | 2015-07-17 | 2025-11-18 | BE Pharbel Manufacturing | Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form |
| TR201801650T1 (tr) * | 2015-08-07 | 2018-03-21 | Santa Farma Ilac Sanayii Anonim Sirketi | Kontrollü salim propi̇veri̇n formülasyonlari |
| JP2017203031A (ja) * | 2017-07-12 | 2017-11-16 | スティッチング グロニンゲン セントル フォー ドラッグ リサーチ | ｐＨ制御パルス送達システム、その調製法及び使用法 |
| SG11202005949UA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
| AU2019275406B2 (en) | 2018-05-24 | 2024-11-14 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| EP3613414A1 (de) * | 2018-08-24 | 2020-02-26 | Dr. Falk Pharma Gmbh | Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| US12472148B2 (en) | 2021-04-26 | 2025-11-18 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| US11896719B2 (en) | 2022-01-24 | 2024-02-13 | Calliditas Therapeutics Ab | Pharmaceutical compositions |
| WO2024206402A1 (en) * | 2023-03-27 | 2024-10-03 | The Cleveland Clinic Foundation | Topical pala therapy for cancer |
| WO2024224407A1 (en) * | 2023-04-28 | 2024-10-31 | Akums Drugs & Pharmaceuticals Limited | Multi-layer pellet formulation and process of preparation thereof |
| CN116650444B (zh) * | 2023-07-31 | 2023-10-31 | 国药集团川抗制药有限公司 | 一种他克莫司缓释药物及其制备方法 |
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|---|---|---|---|---|
| DE3438291A1 (de) * | 1984-10-19 | 1986-04-24 | Röhm GmbH, 6100 Darmstadt | Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimitteln |
| SE8903914D0 (sv) * | 1989-11-22 | 1989-11-22 | Draco Ab | Oral composition for the treatment of inflammatory bowel diseases |
| US5643602A (en) * | 1989-11-22 | 1997-07-01 | Astra Aktiebolag | Oral composition for the treatment of inflammatory bowel disease |
| EP0520119A1 (de) * | 1991-06-17 | 1992-12-30 | Spirig Ag Pharmazeutische Präparate | Neue orale Diclofenaczubereitung |
| DE4402666A1 (de) * | 1994-01-29 | 1995-08-03 | Roehm Gmbh | Verfahren zum kurzzeitigen Behandeln einer Kunststoffschmelze mit einem flüssigen Behandlungsmittel und dabei hergestellter thermoplastischer Kunststoff |
| DE9414066U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| DE9414065U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
| DE19544562B4 (de) * | 1995-11-30 | 2004-05-27 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Poly(meth)acrylimiden mit bei thermischer Belastung verbesserter Farbstabilität und daraus erhältliche Formkörper |
| DE19653606A1 (de) * | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
| DE19653605C2 (de) * | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| DE19718597C1 (de) * | 1997-05-02 | 1999-01-07 | Roehm Gmbh | Zweistufiges Verfahren zur Entwässerung von Kunststoffdispersionen |
| JP2002526294A (ja) * | 1998-09-18 | 2002-08-20 | レーム ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ウント コンパニー コマンディートゲゼルシャフト | 情報担体ディスク生成形体のための成形工具 |
| DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
| DE10220470A1 (de) * | 2002-04-30 | 2003-11-20 | Roehm Gmbh | ph-sensitives Polymer |
| DE19958007A1 (de) * | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| DE19961334A1 (de) * | 1999-12-17 | 2001-06-21 | Roehm Gmbh | Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere |
| DE10011447A1 (de) * | 2000-03-10 | 2001-09-20 | Roehm Gmbh | Dispersion mit nichtionischem Emulgator |
| DE10013029A1 (de) * | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
| DE10065492A1 (de) * | 2000-12-28 | 2003-06-26 | Roehm Gmbh | Diffus ausgestattete Formmassen und hieraus erhältliche Formkörper |
| DE20180358U1 (de) * | 2001-01-29 | 2003-01-30 | Röhm GmbH & Co. KG, 64293 Darmstadt | Lagerstabiles Haft- und Bindemittel für pharmazeutische Anwendungen |
| DE50113344D1 (de) * | 2001-01-31 | 2008-01-17 | Evonik Roehm Gmbh | Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen |
| DE10127134A1 (de) * | 2001-06-05 | 2002-12-12 | Roehm Gmbh | verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß |
| DE10353186A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz |
-
2002
- 2002-10-29 DE DE10250543A patent/DE10250543A1/de not_active Withdrawn
-
2003
- 2003-09-04 WO PCT/EP2003/009800 patent/WO2004039357A1/de not_active Ceased
- 2003-09-04 PL PL374907A patent/PL206707B1/pl unknown
- 2003-09-04 JP JP2004547485A patent/JP4819362B2/ja not_active Expired - Lifetime
- 2003-09-04 US US10/532,831 patent/US20060204576A1/en not_active Abandoned
- 2003-09-04 MX MXPA05004573A patent/MXPA05004573A/es active IP Right Grant
- 2003-09-04 DE DE50310448T patent/DE50310448D1/de not_active Expired - Lifetime
- 2003-09-04 SI SI200331452T patent/SI1556016T1/sl unknown
- 2003-09-04 ES ES03809716T patent/ES2312853T3/es not_active Expired - Lifetime
- 2003-09-04 AT AT03809716T patent/ATE406876T1/de active
- 2003-09-04 AU AU2003266351A patent/AU2003266351A1/en not_active Abandoned
- 2003-09-04 CN CN038240130A patent/CN1688295B/zh not_active Expired - Lifetime
- 2003-09-04 CA CA2502371A patent/CA2502371C/en not_active Expired - Lifetime
- 2003-09-04 KR KR1020057007384A patent/KR20050083847A/ko not_active Ceased
- 2003-09-04 BR BRPI0315740A patent/BRPI0315740B8/pt active IP Right Grant
- 2003-09-04 EP EP03809716A patent/EP1556016B1/de not_active Expired - Lifetime
-
2005
- 2005-03-09 IL IL167334A patent/IL167334A/en unknown
-
2018
- 2018-05-09 US US15/975,090 patent/US20180256606A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE406876T1 (de) | 2008-09-15 |
| EP1556016A1 (de) | 2005-07-27 |
| PL206707B1 (pl) | 2010-09-30 |
| PL374907A1 (en) | 2005-11-14 |
| JP4819362B2 (ja) | 2011-11-24 |
| CA2502371C (en) | 2011-04-12 |
| BRPI0315740B8 (pt) | 2021-05-25 |
| BRPI0315740B1 (pt) | 2018-06-19 |
| CN1688295B (zh) | 2011-08-24 |
| CA2502371A1 (en) | 2004-05-13 |
| IL167334A (en) | 2010-11-30 |
| US20060204576A1 (en) | 2006-09-14 |
| JP2006508087A (ja) | 2006-03-09 |
| DE10250543A1 (de) | 2004-05-19 |
| ES2312853T3 (es) | 2009-03-01 |
| BR0315740A (pt) | 2005-09-06 |
| DE50310448D1 (de) | 2008-10-16 |
| CN1688295A (zh) | 2005-10-26 |
| WO2004039357A1 (de) | 2004-05-13 |
| US20180256606A1 (en) | 2018-09-13 |
| KR20050083847A (ko) | 2005-08-26 |
| EP1556016B1 (de) | 2008-09-03 |
| AU2003266351A1 (en) | 2004-05-25 |
| MXPA05004573A (es) | 2005-11-23 |
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