SI1219594T1 - New esters derived from substituted phenyl-cyclohexyl compounds - Google Patents

New esters derived from substituted phenyl-cyclohexyl compounds

Info

Publication number: SI1219594T1
Authority: SI; Slovenia
Prior art keywords: substituted phenyl; esters derived; new esters; cyclohexyl compounds; cyclohexyl
Prior art date: 1998-11-06

Application number

SI9930540T

Other languages

English (en)

Slovenian (sl)

Inventor

Castillo Nieto Juan Carlos Del

Freixa Maria Chalaux

Clotet Joan Huguet

Mancini Marisabel Mourelle

Ramon Amat Elisabet De

Original Assignee

Laboratorios Vita, S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-06

Filing date

1999-11-04

Publication date

2004-06-30

1999-11-04 Application filed by Laboratorios Vita, S.A. filed Critical Laboratorios Vita, S.A.

2004-06-30 Publication of SI1219594T1 publication Critical patent/SI1219594T1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C219/30—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SI9930540T 1998-11-06 1999-11-04 New esters derived from substituted phenyl-cyclohexyl compounds SI1219594T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES009802329A ES2141688B1 (es)	1998-11-06	1998-11-06	Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos.
PCT/ES1999/000352 WO2000027799A1 (fr)	1998-11-06	1999-11-04	Nouveaux esters derives de composes phenyl-cyclohexyle substitues

Publications (1)

Publication Number	Publication Date
SI1219594T1 true SI1219594T1 (en)	2004-06-30

Family

ID=8305698

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SI9930541T SI1219623T1 (en)	1998-11-06	1999-11-04	New esters derived from substituted phenyl-cyclohexyl compounds
SI9930540T SI1219594T1 (en)	1998-11-06	1999-11-04	New esters derived from substituted phenyl-cyclohexyl compounds
SI9930450T SI1127871T1 (en)	1998-11-06	1999-11-04	New esters derived from substituted phenyl-cyclohexyl compounds

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SI9930541T SI1219623T1 (en)	1998-11-06	1999-11-04	New esters derived from substituted phenyl-cyclohexyl compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SI9930450T SI1127871T1 (en)	1998-11-06	1999-11-04	New esters derived from substituted phenyl-cyclohexyl compounds

Country Status (39)

Country	Link
US (1)	US6455585B1 (fr)
EP (3)	EP1219594B1 (fr)
JP (1)	JP2002529442A (fr)
KR (1)	KR100453613B1 (fr)
CN (1)	CN1176902C (fr)
AP (1)	AP1222A (fr)
AT (3)	ATE257837T1 (fr)
AU (1)	AU755681B2 (fr)
BG (1)	BG105556A (fr)
BR (1)	BR9915727A (fr)
CA (1)	CA2349245A1 (fr)
CR (1)	CR6368A (fr)
CU (1)	CU23006A3 (fr)
CZ (1)	CZ20011500A3 (fr)
DE (3)	DE69914231T2 (fr)
DK (3)	DK1219623T3 (fr)
EA (1)	EA003742B1 (fr)
EE (1)	EE200100246A (fr)
ES (4)	ES2141688B1 (fr)
GE (1)	GEP20033116B (fr)
HR (1)	HRP20010412B1 (fr)
HU (1)	HUP0104218A3 (fr)
ID (1)	ID29017A (fr)
IL (1)	IL142592A0 (fr)
IS (1)	IS5934A (fr)
MA (1)	MA26765A1 (fr)
MX (1)	MXPA01004432A (fr)
NO (1)	NO20012234D0 (fr)
NZ (1)	NZ511739A (fr)
OA (1)	OA11672A (fr)
PL (1)	PL347492A1 (fr)
PT (3)	PT1127871E (fr)
SI (3)	SI1219623T1 (fr)
SK (1)	SK284068B6 (fr)
TR (3)	TR200200415T2 (fr)
UA (1)	UA59477C2 (fr)
WO (1)	WO2000027799A1 (fr)
YU (1)	YU29601A (fr)
ZA (1)	ZA200104026B (fr)

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ES2160534B1 (es) *	1999-12-30	2002-04-16	Vita Invest Sa	Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil) fenilo.
DE10049483A1 (de) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituierte 1-Aminobutan-3-ol-Derivate
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
WO2004026291A1 (fr) *	2002-08-28	2004-04-01	Shuyi Zhang	Formulations orales d'ibuprofene et de tramadol, methodes de preparation de ces dernieres
EP1562567B1 (fr)	2002-11-22	2017-06-14	Grünenthal GmbH	Association d'analgesiques selectionnes et d'inhibiteurs de la cox ii
US20040248979A1 (en) *	2003-06-03	2004-12-09	Dynogen Pharmaceuticals, Inc.	Method of treating lower urinary tract disorders
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
DE102004032051A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
US8075872B2 (en)	2003-08-06	2011-12-13	Gruenenthal Gmbh	Abuse-proofed dosage form
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102004034619A1 (de) *	2004-07-16	2006-02-23	Grünenthal GmbH	Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102007011485A1 (de)	2007-03-07	2008-09-11	Grünenthal GmbH	Darreichungsform mit erschwertem Missbrauch
US8383152B2 (en)	2008-01-25	2013-02-26	Gruenenthal Gmbh	Pharmaceutical dosage form
TWI524904B (zh)	2008-05-09	2016-03-11	歌林達股份有限公司	製備醫藥用固體劑型，尤指錠劑之方法，及製備固體劑型，尤指錠劑之前驅物之方法
NZ596668A (en)	2009-07-22	2013-09-27	Gruenenthal Chemie	Oxidation-stabilized tamper-resistant dosage form
JP5667183B2 (ja)	2009-07-22	2015-02-12	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	加熱溶融押出成型した制御放出性投与剤型
EP2383255A1 (fr)	2010-04-28	2011-11-02	Lacer, S.A.	Nouveaux composés, synthèse et utilisation dans le traitement de la douleur
MX2013002293A (es)	2010-09-02	2013-05-09	Gruenenthal Gmbh	Forma de dosificacion resistente a alteracion que comprende un polimero anionico.
ES2486791T3 (es)	2010-09-02	2014-08-19	Grünenthal GmbH	Forma de dosificación resistente a la manipulación que comprende una sal inorgánica
WO2012100423A1 (fr) *	2011-01-27	2012-08-02	Eli Lilly And Company	Composés analgésiques, procédés, et formulations
EP2530072A1 (fr)	2011-06-03	2012-12-05	Lacer, S.A.	Nouveaux composés, synthèse et utilisation dans le traitement de la douleur
US10702485B2 (en)	2011-07-09	2020-07-07	Syntrix Biosystems Inc.	Compositions and methods for overcoming resistance to tramadol
PE20141650A1 (es)	2011-07-29	2014-11-22	Gruenenthal Chemie	Tableta a prueba de alteracion que proporciona liberacion inmediata del farmaco
EA201400172A1 (ru)	2011-07-29	2014-06-30	Грюненталь Гмбх	Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
WO2013127831A1 (fr)	2012-02-28	2013-09-06	Grünenthal GmbH	Forme pharmaceutique inviolable comprenant un composé pharmacologiquement actif et un polymère anionique
ES2692944T3 (es)	2012-04-18	2018-12-05	Grünenthal GmbH	Forma de dosificación farmacéutica resistente a la manipulación y resistente a la descarga rápida de la dosis
US9339484B2 (en) *	2012-05-10	2016-05-17	Cellix Bio Private Limited	Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
BR112015026549A2 (pt)	2013-05-29	2017-07-25	Gruenenthal Gmbh	forma de dosagem à prova de violação contendo uma ou mais partículas
US9737490B2 (en)	2013-05-29	2017-08-22	Grünenthal GmbH	Tamper resistant dosage form with bimodal release profile
AU2014289187B2 (en)	2013-07-12	2019-07-11	Grunenthal Gmbh	Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
AU2014356581C1 (en)	2013-11-26	2020-05-28	Grunenthal Gmbh	Preparation of a powdery pharmaceutical composition by means of cryo-milling
MX2016014738A (es)	2014-05-12	2017-03-06	Gruenenthal Gmbh	Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol.
BR112017021475A2 (pt)	2015-04-24	2018-07-10	Gruenenthal Gmbh	forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
CA2998259A1 (fr)	2015-09-10	2017-03-16	Grunenthal Gmbh	Protection contre un surdosage par voie orale a l'aide de formulations a liberation immediate dissuasives d'abus

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US3652589A (en) *	1967-07-27	1972-03-28	Gruenenthal Chemie	1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
DE19525137C2 (de) *	1995-07-11	2003-02-27	Gruenenthal Gmbh	6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) *	1996-03-13	1997-09-18	Gruenenthal Gmbh	Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe

1998
- 1998-11-06 ES ES009802329A patent/ES2141688B1/es not_active Expired - Fee Related
1999
- 1999-04-11 UA UA2001063799A patent/UA59477C2/uk unknown
- 1999-11-04 DE DE69914231T patent/DE69914231T2/de not_active Expired - Fee Related
- 1999-11-04 OA OA1200100111A patent/OA11672A/en unknown
- 1999-11-04 BR BR9915727-6A patent/BR9915727A/pt not_active IP Right Cessation
- 1999-11-04 DK DK02075837T patent/DK1219623T3/da active
- 1999-11-04 EP EP02075838A patent/EP1219594B1/fr not_active Expired - Lifetime
- 1999-11-04 AP APAP/P/2001/002161A patent/AP1222A/en active
- 1999-11-04 EE EEP200100246A patent/EE200100246A/xx unknown
- 1999-11-04 TR TR2002/00415T patent/TR200200415T2/xx unknown
- 1999-11-04 SI SI9930541T patent/SI1219623T1/xx unknown
- 1999-11-04 AT AT02075837T patent/ATE257837T1/de not_active IP Right Cessation
- 1999-11-04 KR KR10-2001-7005667A patent/KR100453613B1/ko not_active Expired - Fee Related
- 1999-11-04 US US09/831,177 patent/US6455585B1/en not_active Expired - Fee Related
- 1999-11-04 EA EA200100476A patent/EA003742B1/ru not_active IP Right Cessation
- 1999-11-04 ES ES02075837T patent/ES2213731T3/es not_active Expired - Lifetime
- 1999-11-04 HR HR20010412A patent/HRP20010412B1/xx not_active IP Right Cessation
- 1999-11-04 TR TR2002/00416T patent/TR200200416T2/xx unknown
- 1999-11-04 TR TR2001/01160T patent/TR200101160T2/xx unknown
- 1999-11-04 CZ CZ20011500A patent/CZ20011500A3/cs unknown
- 1999-11-04 IL IL14259299A patent/IL142592A0/xx unknown
- 1999-11-04 NZ NZ511739A patent/NZ511739A/xx unknown
- 1999-11-04 AT AT02075838T patent/ATE257817T1/de not_active IP Right Cessation
- 1999-11-04 AT AT99953994T patent/ATE249418T1/de not_active IP Right Cessation
- 1999-11-04 YU YU29601A patent/YU29601A/sh unknown
- 1999-11-04 SI SI9930540T patent/SI1219594T1/xx unknown
- 1999-11-04 DK DK99953994T patent/DK1127871T3/da active
- 1999-11-04 PT PT99953994T patent/PT1127871E/pt unknown
- 1999-11-04 PL PL99347492A patent/PL347492A1/xx unknown
- 1999-11-04 CN CNB998129259A patent/CN1176902C/zh not_active Expired - Fee Related
- 1999-11-04 DK DK02075838T patent/DK1219594T3/da active
- 1999-11-04 SI SI9930450T patent/SI1127871T1/xx unknown
- 1999-11-04 ID IDW00200101215A patent/ID29017A/id unknown
- 1999-11-04 WO PCT/ES1999/000352 patent/WO2000027799A1/fr not_active Ceased
- 1999-11-04 ES ES99953994T patent/ES2207298T3/es not_active Expired - Lifetime
- 1999-11-04 SK SK584-2001A patent/SK284068B6/sk unknown
- 1999-11-04 ES ES02075838T patent/ES2213732T3/es not_active Expired - Lifetime
- 1999-11-04 JP JP2000580979A patent/JP2002529442A/ja active Pending
- 1999-11-04 PT PT02075838T patent/PT1219594E/pt unknown
- 1999-11-04 MX MXPA01004432A patent/MXPA01004432A/es unknown
- 1999-11-04 CA CA002349245A patent/CA2349245A1/fr not_active Abandoned
- 1999-11-04 EP EP99953994A patent/EP1127871B1/fr not_active Expired - Lifetime
- 1999-11-04 EP EP02075837A patent/EP1219623B1/fr not_active Expired - Lifetime
- 1999-11-04 DE DE69914229T patent/DE69914229T2/de not_active Expired - Fee Related
- 1999-11-04 HU HU0104218A patent/HUP0104218A3/hu unknown
- 1999-11-04 AU AU10473/00A patent/AU755681B2/en not_active Ceased
- 1999-11-04 DE DE69911235T patent/DE69911235T2/de not_active Expired - Fee Related
- 1999-11-04 GE GEAP19995930A patent/GEP20033116B/en unknown
- 1999-11-04 PT PT02075837T patent/PT1219623E/pt unknown
2001
- 2001-05-03 IS IS5934A patent/IS5934A/is unknown
- 2001-05-04 NO NO20012234A patent/NO20012234D0/no unknown
- 2001-05-07 CU CU2001010920010109A patent/CU23006A3/es unknown
- 2001-05-16 CR CR6368A patent/CR6368A/es not_active Application Discontinuation
- 2001-05-17 ZA ZA200104026A patent/ZA200104026B/en unknown
- 2001-05-23 MA MA26211A patent/MA26765A1/fr unknown
- 2001-06-01 BG BG105556A patent/BG105556A/xx unknown

Also Published As

Publication number	Publication date
UA59477C2 (uk)	2003-09-15
AP1222A (en)	2003-11-06
SK284068B6 (sk)	2004-09-08
EP1219623A1 (fr)	2002-07-03
GEP20033116B (en)	2003-11-25
EP1127871A1 (fr)	2001-08-29
DK1127871T3 (da)	2003-11-24
ES2213732T3 (es)	2004-09-01
TR200200416T2 (tr)	2003-01-21
ES2213731T3 (es)	2004-09-01
CZ20011500A3 (cs)	2001-09-12
CR6368A (es)	2002-04-08
DE69911235D1 (de)	2003-10-16
CN1176902C (zh)	2004-11-24
EA200100476A1 (ru)	2002-02-28
KR20010080942A (ko)	2001-08-25
EP1219594B1 (fr)	2004-01-14
MA26765A1 (fr)	2004-12-20
DE69911235T2 (de)	2004-07-01
EA003742B1 (ru)	2003-08-28
ES2141688B1 (es)	2001-02-01
MXPA01004432A (es)	2002-09-18
EP1219623B1 (fr)	2004-01-14
DE69914229T2 (de)	2004-12-09
PT1127871E (pt)	2003-12-31
AU755681B2 (en)	2002-12-19
CN1325377A (zh)	2001-12-05
SI1219623T1 (en)	2004-06-30
CU23006A3 (es)	2004-12-17
HUP0104218A2 (hu)	2002-03-28
ES2207298T3 (es)	2004-05-16
PT1219594E (pt)	2004-04-30
HRP20010412A2 (en)	2002-12-31
YU29601A (sh)	2003-04-30
EP1127871B1 (fr)	2003-09-10
ATE257817T1 (de)	2004-01-15
JP2002529442A (ja)	2002-09-10
DE69914231T2 (de)	2004-11-11
BG105556A (en)	2001-12-29
IS5934A (is)	2001-05-03
SK5842001A3 (en)	2001-12-03
DK1219594T3 (da)	2004-04-19
PT1219623E (pt)	2004-04-30
NO20012234L (no)	2001-05-04
WO2000027799A1 (fr)	2000-05-18
KR100453613B1 (ko)	2004-10-20
ATE249418T1 (de)	2003-09-15
NZ511739A (en)	2002-11-26
OA11672A (en)	2005-01-12
PL347492A1 (en)	2002-04-08
IL142592A0 (en)	2002-03-10
ATE257837T1 (de)	2004-01-15
ZA200104026B (en)	2002-05-17
ES2141688A1 (es)	2000-05-16
ID29017A (id)	2001-07-26
EP1219594A1 (fr)	2002-07-03
DK1219623T3 (da)	2004-04-19
EE200100246A (et)	2002-12-16
DE69914229D1 (de)	2004-02-19
SI1127871T1 (en)	2004-02-29
NO20012234D0 (no)	2001-05-04
US6455585B1 (en)	2002-09-24
TR200200415T2 (tr)	2002-06-21
AU1047300A (en)	2000-05-29
HUP0104218A3 (en)	2002-11-28
TR200101160T2 (tr)	2002-01-21
CA2349245A1 (fr)	2000-05-18
DE69914231D1 (de)	2004-02-19
HRP20010412B1 (en)	2004-04-30
BR9915727A (pt)	2001-09-04

Publication	Publication Date	Title
HRP20010412B1 (en)	2004-04-30	New esters derived from substituted phenyl-cyclohexyl compounds
ZA99680B (en)	1999-07-28	Ester compounds.
GB9810193D0 (en)	1998-07-08	Novel compounds
IL141166A0 (en)	2002-02-10	New compounds
HU9901927D0 (en)	1999-08-30	Ester compounds
HUP0101446A3 (en)	2002-10-28	New compounds
GB9806105D0 (en)	1998-05-20	Novel compounds
GB9808584D0 (en)	1998-06-24	Novel compounds
GB9803306D0 (en)	1998-04-15	Novel compounds
GB9803650D0 (en)	1998-04-15	Novel compounds
GB9804007D0 (en)	1998-04-22	Novel compounds
GB9805100D0 (en)	1998-05-06	Novel compounds
GB9805484D0 (en)	1998-05-13	Novel compounds
GB9805959D0 (en)	1998-05-20	Novel compounds
GB9802698D0 (en)	1998-04-01	Novel compounds
GB9806115D0 (en)	1998-05-20	Novel compounds
GB9806214D0 (en)	1998-05-20	Novel compounds
GB9806454D0 (en)	1998-05-27	Novel compounds
GB9808212D0 (en)	1998-06-17	Novel compounds
GB9808214D0 (en)	1998-06-17	Novel compounds
GB9808217D0 (en)	1998-06-17	Novel compounds
GB9808373D0 (en)	1998-06-17	Novel compounds
GB9808570D0 (en)	1998-06-24	Novel compounds
GB9803194D0 (en)	1998-04-08	Novel compounds
GB9808843D0 (en)	1998-06-24	Novel compounds