SI1252155T1 - Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- (4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one - Google Patents

Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- (4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one

Info

Publication number: SI1252155T1
Authority: SI; Slovenia
Prior art keywords: benzopyran; piperidinyl; chlorophenyl; dihydroxy; cis
Prior art date: 2000-01-18

Application number

SI200130293T

Other languages

English (en)

Slovenian (sl)

Inventor

Kurt M. Kesseler

Original Assignee

Aventis Pharmaceuticals Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2001-01-08

Publication date

2005-06-30

2001-01-08 Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.

2005-06-30 Publication of SI1252155T1 publication Critical patent/SI1252155T1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

SI200130293T 2000-01-18 2001-01-08 Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- (4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one SI1252155T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US48781500A	2000-01-18	2000-01-18
PCT/US2001/000520 WO2001053294A1 (fr)	2000-01-18	2001-01-08	Solvate d'ethanol sous forme (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one
EP01902993A EP1252155B1 (fr)	2000-01-18	2001-01-08	Solvate d'ethanol sous forme (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- [4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (1)

Publication Number	Publication Date
SI1252155T1 true SI1252155T1 (en)	2005-06-30

Family

ID=23937213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200130293T SI1252155T1 (en)	2000-01-18	2001-01-08	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- (4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one

Country Status (26)

Country	Link
EP (1)	EP1252155B1 (fr)
JP (1)	JP2003520798A (fr)
KR (1)	KR100825530B1 (fr)
CN (1)	CN1395577A (fr)
AR (1)	AR027226A1 (fr)
AT (1)	ATE284400T1 (fr)
AU (1)	AU2001230869A1 (fr)
BR (1)	BR0107724A (fr)
CA (1)	CA2397594C (fr)
CZ (1)	CZ301235B6 (fr)
DE (1)	DE60107652T2 (fr)
DK (1)	DK1252155T3 (fr)
EA (1)	EA005182B1 (fr)
ES (1)	ES2228800T3 (fr)
HU (1)	HU225155B1 (fr)
IL (2)	IL150643A0 (fr)
MX (1)	MXPA02006965A (fr)
NO (1)	NO322626B1 (fr)
NZ (1)	NZ520281A (fr)
PL (1)	PL201690B1 (fr)
PT (1)	PT1252155E (fr)
SI (1)	SI1252155T1 (fr)
SK (1)	SK287216B6 (fr)
TW (1)	TWI293072B (fr)
WO (1)	WO2001053294A1 (fr)
ZA (1)	ZA200205640B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20190175598A1 (en)	2016-08-23	2019-06-13	Eisai R&D Management Co., Ltd.	Combination therapies for the treatment of hepatocellular carcinoma
US11083722B2 (en)	2017-03-16	2021-08-10	Eisai R&D Management Co., Ltd.	Combination therapies for the treatment of breast cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN164232B (fr) *	1986-04-11	1989-02-04	Hoechst India
US5284856A (en) *	1988-10-28	1994-02-08	Hoechst Aktiengesellschaft	Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
DE3836676A1 (de) *	1988-10-28	1990-05-03	Hoechst Ag	Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5908934A (en) *	1996-09-26	1999-06-01	Bristol-Myers Squibb Company	Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

2001
- 2001-01-08 AU AU2001230869A patent/AU2001230869A1/en not_active Abandoned
- 2001-01-08 CA CA2397594A patent/CA2397594C/fr not_active Expired - Fee Related
- 2001-01-08 CZ CZ20022467A patent/CZ301235B6/cs not_active IP Right Cessation
- 2001-01-08 SK SK1037-2002A patent/SK287216B6/sk not_active IP Right Cessation
- 2001-01-08 WO PCT/US2001/000520 patent/WO2001053294A1/fr not_active Ceased
- 2001-01-08 PT PT01902993T patent/PT1252155E/pt unknown
- 2001-01-08 ES ES01902993T patent/ES2228800T3/es not_active Expired - Lifetime
- 2001-01-08 DE DE60107652T patent/DE60107652T2/de not_active Expired - Lifetime
- 2001-01-08 BR BR0107724-4A patent/BR0107724A/pt not_active Application Discontinuation
- 2001-01-08 PL PL355992A patent/PL201690B1/pl not_active IP Right Cessation
- 2001-01-08 MX MXPA02006965A patent/MXPA02006965A/es active IP Right Grant
- 2001-01-08 JP JP2001553768A patent/JP2003520798A/ja active Pending
- 2001-01-08 KR KR1020027009140A patent/KR100825530B1/ko not_active Expired - Fee Related
- 2001-01-08 HU HU0204297A patent/HU225155B1/hu not_active IP Right Cessation
- 2001-01-08 SI SI200130293T patent/SI1252155T1/xx unknown
- 2001-01-08 CN CN01803857A patent/CN1395577A/zh active Pending
- 2001-01-08 NZ NZ520281A patent/NZ520281A/en not_active IP Right Cessation
- 2001-01-08 IL IL15064301A patent/IL150643A0/xx unknown
- 2001-01-08 AT AT01902993T patent/ATE284400T1/de active
- 2001-01-08 DK DK01902993T patent/DK1252155T3/da active
- 2001-01-08 EA EA200200776A patent/EA005182B1/ru not_active IP Right Cessation
- 2001-01-08 EP EP01902993A patent/EP1252155B1/fr not_active Expired - Lifetime
- 2001-01-17 AR ARP010100186A patent/AR027226A1/es not_active Application Discontinuation
- 2001-01-17 TW TW090101052A patent/TWI293072B/zh not_active IP Right Cessation
2002
- 2002-07-08 IL IL150643A patent/IL150643A/en not_active IP Right Cessation
- 2002-07-12 NO NO20023385A patent/NO322626B1/no not_active IP Right Cessation
- 2002-07-15 ZA ZA200205640A patent/ZA200205640B/en unknown

Also Published As

Publication number	Publication date
DE60107652D1 (de)	2005-01-13
PT1252155E (pt)	2005-04-29
WO2001053294A1 (fr)	2001-07-26
TWI293072B (en)	2008-02-01
NZ520281A (en)	2004-04-30
EP1252155A1 (fr)	2002-10-30
CZ301235B6 (cs)	2009-12-16
CN1395577A (zh)	2003-02-05
HU225155B1 (en)	2006-07-28
DK1252155T3 (da)	2005-04-04
NO322626B1 (no)	2006-11-06
NO20023385L (no)	2002-08-27
KR100825530B1 (ko)	2008-04-25
SK287216B6 (sk)	2010-03-08
NO20023385D0 (no)	2002-07-12
SK10372002A3 (sk)	2002-12-03
IL150643A (en)	2009-08-03
MXPA02006965A (es)	2004-09-06
AU2001230869A1 (en)	2001-07-31
HUP0204297A3 (en)	2005-04-28
HUP0204297A2 (hu)	2003-04-28
EA200200776A1 (ru)	2002-12-26
PL355992A1 (en)	2004-05-31
KR20020069514A (ko)	2002-09-04
BR0107724A (pt)	2002-10-01
JP2003520798A (ja)	2003-07-08
EP1252155B1 (fr)	2004-12-08
CA2397594C (fr)	2010-03-23
ZA200205640B (en)	2003-11-26
EA005182B1 (ru)	2004-12-30
DE60107652T2 (de)	2005-12-22
IL150643A0 (en)	2003-02-12
PL201690B1 (pl)	2009-04-30
CA2397594A1 (fr)	2001-07-26
AR027226A1 (es)	2003-03-19
CZ20022467A3 (cs)	2002-10-16
ES2228800T3 (es)	2005-04-16
ATE284400T1 (de)	2004-12-15

Publication	Publication Date	Title
HUS1300057I1 (hu)	2016-04-28	Új fenil-propargil-éter-származékok
AU143493S (en)	2001-04-10	Tubular package for door hardware
AR028343A1 (es)	2003-05-07	Derivados de pirrolidina y piperidina
AR028596A1 (es)	2003-05-14	Nuevos derivados de fenilglicina
IL154343A0 (en)	2003-09-17	Phenoxybenzylamine derivatives as selective serotonin re-uptake inhibitors
HUP0202578A3 (en)	2005-02-28	Novel derivatives of flavones, xanthones and coumarins
IL152893A0 (en)	2003-06-24	Novel benzofuran derivatives
IL154240A0 (en)	2003-07-31	4-pyrimidinamine derivatives, pharmaceutical compositions and related methods
SI1252155T1 (en)	2005-06-30	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8- (4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one
AU2001271018A1 (en)	2002-01-14	Gpr14 antagonist
AU2001271280A1 (en)	2001-12-11	Preparation of 4-hydroxy-3(2h)-furanones
AU4834001A (en)	2001-10-23	Method for producing benzo annelated heterocycles
PT1440067E (pt)	2005-02-28	Derivados n-formilo de paroxetina
AUPQ825300A0 (en)	2000-07-13	Method of sentence analysis
ATE273303T1 (de)	2004-08-15	Pseudopolymorph von (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8(4r-(3 -hydroxy-1-methyl)piperidinyl)- 4h-1-benzopyran-4-on hydrochlorid
PL347407A1 (en)	2001-11-19	Method of obtaining derivatives of 5,6,7,8-tetrahydronaphtalen-2-ole
TW435780U (en)	2001-05-16	Repetition pianissimo controller
AU2001293825A1 (en)	2002-04-08	Hollow block
TW491048U (en)	2002-06-11	Improved structure of bracket for keyboard
HUP0301741A3 (en)	2005-01-28	Method for producing 4-bromine-aniline derivatives
PL339237A1 (en)	2001-10-08	Method of obtaining anhydrous ethanol
GB0009453D0 (en)	2000-06-07	PT1B-Inhibiting phenanthrenyl derivatives
SI1212312T1 (en)	2003-12-31	Novel derivatives of flavones, xanthones and coumarins
SI1280792T1 (en)	2004-12-31	Method for producing benzo annelated heterocycles
TW521610U (en)	2003-02-21	Structure of moveable enclosed display closet