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SI1051170T1 - Application of substituted aminomethyl chromans in order to prevent neural degeneration and to promote neural regeneration - Google Patents

Application of substituted aminomethyl chromans in order to prevent neural degeneration and to promote neural regeneration

Info

Publication number
SI1051170T1
SI1051170T1 SI9830038T SI9830038T SI1051170T1 SI 1051170 T1 SI1051170 T1 SI 1051170T1 SI 9830038 T SI9830038 T SI 9830038T SI 9830038 T SI9830038 T SI 9830038T SI 1051170 T1 SI1051170 T1 SI 1051170T1
Authority
SI
Slovenia
Prior art keywords
application
order
neural
substituted aminomethyl
promote
Prior art date
Application number
SI9830038T
Other languages
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Ervin Horvath
Reinhard Jork
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SI1051170T1 publication Critical patent/SI1051170T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SI9830038T 1997-11-24 1998-11-11 Application of substituted aminomethyl chromans in order to prevent neural degeneration and to promote neural regeneration SI1051170T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
PCT/EP1998/007197 WO1999026621A1 (de) 1997-11-24 1998-11-11 Verwendung von substituierten aminomethyl-chromanen zur verhinderung der neuronalen degeneration und zur förderung der neuronalen regeneration
EP98961174A EP1051170B1 (de) 1997-11-24 1998-11-11 Verwendung von substituierten aminomethyl-chromanen zur verhinderung der neuronalen degeneration und zur förderung der neuronalen regeneration

Publications (1)

Publication Number Publication Date
SI1051170T1 true SI1051170T1 (en) 2001-12-31

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830038T SI1051170T1 (en) 1997-11-24 1998-11-11 Application of substituted aminomethyl chromans in order to prevent neural degeneration and to promote neural regeneration

Country Status (30)

Country Link
US (2) US6235774B1 (es)
EP (1) EP1051170B1 (es)
JP (1) JP2001523716A (es)
KR (1) KR20010032357A (es)
CN (1) CN1134256C (es)
AR (1) AR016973A1 (es)
AT (1) ATE206615T1 (es)
AU (1) AU745759B2 (es)
BG (1) BG64167B1 (es)
CA (1) CA2311126A1 (es)
DE (2) DE19751949A1 (es)
DK (1) DK1051170T3 (es)
ES (1) ES2164465T3 (es)
HN (1) HN1998000169A (es)
HU (1) HUP0004369A3 (es)
IL (1) IL135904A (es)
IS (1) IS5496A (es)
MY (1) MY118414A (es)
NO (1) NO20002638L (es)
NZ (1) NZ504656A (es)
PE (1) PE134999A1 (es)
PL (1) PL340674A1 (es)
PT (1) PT1051170E (es)
RU (1) RU2217140C2 (es)
SI (1) SI1051170T1 (es)
SV (1) SV1998000138A (es)
TR (1) TR200001471T2 (es)
TW (1) TW524690B (es)
WO (1) WO1999026621A1 (es)
ZA (1) ZA9810668B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
EP1263434A1 (en) * 2000-03-17 2002-12-11 Alcon, Inc Compounds with 5-ht 2 and 5-ht 1a agonist activity for treating glaucoma
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
MXPA04000775A (es) * 2001-07-26 2004-04-20 Merck Patent Ges Mit Baschrank Uso novedoso del 2 -[5-(4-fluorofenil) -3-piridilmetilamino-metil] -cromano y sus sales fisiologicamente aceptables.
CA2458628A1 (en) * 2001-09-12 2003-03-20 Merck Patent Gesellschaft Mit Beschraenkter Haftung Use of substituted aminomethyl chromans in the treatment of movement disorders
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7470798B2 (en) * 2003-09-19 2008-12-30 Edison Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
JP7187437B2 (ja) 2016-07-29 2022-12-12 サノビオン ファーマシューティカルズ インク 化合物および組成物ならびにそれらの使用
EP3490607A4 (en) 2016-07-29 2020-04-08 Sunovion Pharmaceuticals Inc. COMPOUNDS AND COMPOSITIONS, AND USES THEREOF
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
SG11202000669VA (en) 2017-08-02 2020-02-27 Sunovion Pharmaceuticals Inc Isochroman compounds and uses thereof
KR20210139376A (ko) 2019-03-14 2021-11-22 선오비온 파마슈티컬스 인코포레이티드 이소크로마닐 화합물의 염, 및 이의 결정성 형태, 제조방법, 치료 용도 및 약제학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
CN1279604A (zh) 2001-01-10
TW524690B (en) 2003-03-21
US6235774B1 (en) 2001-05-22
NZ504656A (en) 2002-02-01
KR20010032357A (ko) 2001-04-16
CA2311126A1 (en) 1999-06-03
MY118414A (en) 2004-10-30
DE19751949A1 (de) 1999-05-27
PE134999A1 (es) 2000-03-05
US20010018530A1 (en) 2001-08-30
EP1051170B1 (de) 2001-10-10
NO20002638D0 (no) 2000-05-23
IL135904A0 (en) 2001-05-20
PT1051170E (pt) 2002-02-28
AU745759B2 (en) 2002-03-28
BG64167B1 (bg) 2004-03-31
IS5496A (is) 2000-05-15
ES2164465T3 (es) 2002-02-16
PL340674A1 (en) 2001-02-12
DK1051170T3 (da) 2001-12-27
HUP0004369A2 (hu) 2001-04-28
SV1998000138A (es) 1999-05-25
IL135904A (en) 2003-07-06
TR200001471T2 (tr) 2000-10-23
CN1134256C (zh) 2004-01-14
RU2217140C2 (ru) 2003-11-27
EP1051170A1 (de) 2000-11-15
WO1999026621A1 (de) 1999-06-03
AU1668599A (en) 1999-06-15
JP2001523716A (ja) 2001-11-27
NO20002638L (no) 2000-05-23
ATE206615T1 (de) 2001-10-15
DE59801724D1 (de) 2001-11-15
HUP0004369A3 (en) 2002-04-29
BG104466A (en) 2001-02-28
US6331561B2 (en) 2001-12-18
HN1998000169A (es) 1999-11-03
ZA9810668B (en) 1999-05-26
AR016973A1 (es) 2001-08-01

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