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DK1051170T3 - Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration - Google Patents

Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration

Info

Publication number
DK1051170T3
DK1051170T3 DK98961174T DK98961174T DK1051170T3 DK 1051170 T3 DK1051170 T3 DK 1051170T3 DK 98961174 T DK98961174 T DK 98961174T DK 98961174 T DK98961174 T DK 98961174T DK 1051170 T3 DK1051170 T3 DK 1051170T3
Authority
DK
Denmark
Prior art keywords
nerve
chromas
prevention
accelerate
substituted aminomethyl
Prior art date
Application number
DK98961174T
Other languages
Danish (da)
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Reinhard Jork
Ervin Horvath
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK1051170T3 publication Critical patent/DK1051170T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98961174T 1997-11-24 1998-11-11 Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration DK1051170T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
PCT/EP1998/007197 WO1999026621A1 (de) 1997-11-24 1998-11-11 Verwendung von substituierten aminomethyl-chromanen zur verhinderung der neuronalen degeneration und zur förderung der neuronalen regeneration

Publications (1)

Publication Number Publication Date
DK1051170T3 true DK1051170T3 (da) 2001-12-27

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98961174T DK1051170T3 (da) 1997-11-24 1998-11-11 Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration

Country Status (30)

Country Link
US (2) US6235774B1 (es)
EP (1) EP1051170B1 (es)
JP (1) JP2001523716A (es)
KR (1) KR20010032357A (es)
CN (1) CN1134256C (es)
AR (1) AR016973A1 (es)
AT (1) ATE206615T1 (es)
AU (1) AU745759B2 (es)
BG (1) BG64167B1 (es)
CA (1) CA2311126A1 (es)
DE (2) DE19751949A1 (es)
DK (1) DK1051170T3 (es)
ES (1) ES2164465T3 (es)
HN (1) HN1998000169A (es)
HU (1) HUP0004369A3 (es)
IL (1) IL135904A (es)
IS (1) IS5496A (es)
MY (1) MY118414A (es)
NO (1) NO20002638D0 (es)
NZ (1) NZ504656A (es)
PE (1) PE134999A1 (es)
PL (1) PL340674A1 (es)
PT (1) PT1051170E (es)
RU (1) RU2217140C2 (es)
SI (1) SI1051170T1 (es)
SV (1) SV1998000138A (es)
TR (1) TR200001471T2 (es)
TW (1) TW524690B (es)
WO (1) WO1999026621A1 (es)
ZA (1) ZA9810668B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
EP1263434A1 (en) * 2000-03-17 2002-12-11 Alcon, Inc Compounds with 5-ht 2 and 5-ht 1a agonist activity for treating glaucoma
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
HUP0402092A3 (en) * 2001-07-26 2010-06-28 Merck Patent Gmbh Use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts for preparation of pharmaceutical compositions
US20040235920A1 (en) * 2001-09-12 2004-11-25 Gerd Bartoszyk Novel use of substituted aminomethyl chromans for the treatment of movement disorders and of adverse effects induced by drugs administered to treat extrapyramidal movement disorders
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005032544A1 (en) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Treatment of mitochondrial diseases
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
KR20190065246A (ko) 2016-07-29 2019-06-11 선오비온 파마슈티컬스 인코포레이티드 화합물 및 조성물 및 이들의 용도
US10196403B2 (en) 2016-07-29 2019-02-05 Sunovion Pharmaceuticals Inc. Compounds and compositions and uses thereof
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
JP7191085B2 (ja) * 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク イソクロマン化合物およびその使用
MX2021010880A (es) 2019-03-14 2022-01-18 Sunovion Pharmaceuticals Inc Sales de un compuesto de isocromanilo y formas cristalinas, procesos de preparacion, usos terapeuticos y composiciones farmaceuticas de las mismas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
EP1051170B1 (de) 2001-10-10
HN1998000169A (es) 1999-11-03
JP2001523716A (ja) 2001-11-27
US6235774B1 (en) 2001-05-22
NO20002638L (no) 2000-05-23
HUP0004369A3 (en) 2002-04-29
EP1051170A1 (de) 2000-11-15
CN1279604A (zh) 2001-01-10
IL135904A (en) 2003-07-06
DE19751949A1 (de) 1999-05-27
RU2217140C2 (ru) 2003-11-27
AR016973A1 (es) 2001-08-01
AU745759B2 (en) 2002-03-28
ES2164465T3 (es) 2002-02-16
SV1998000138A (es) 1999-05-25
TR200001471T2 (tr) 2000-10-23
CN1134256C (zh) 2004-01-14
WO1999026621A1 (de) 1999-06-03
IS5496A (is) 2000-05-15
KR20010032357A (ko) 2001-04-16
ATE206615T1 (de) 2001-10-15
PT1051170E (pt) 2002-02-28
BG104466A (en) 2001-02-28
NO20002638D0 (no) 2000-05-23
TW524690B (en) 2003-03-21
US6331561B2 (en) 2001-12-18
PE134999A1 (es) 2000-03-05
SI1051170T1 (en) 2001-12-31
IL135904A0 (en) 2001-05-20
HUP0004369A2 (hu) 2001-04-28
PL340674A1 (en) 2001-02-12
ZA9810668B (en) 1999-05-26
MY118414A (en) 2004-10-30
US20010018530A1 (en) 2001-08-30
DE59801724D1 (de) 2001-11-15
AU1668599A (en) 1999-06-15
CA2311126A1 (en) 1999-06-03
NZ504656A (en) 2002-02-01
BG64167B1 (bg) 2004-03-31

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