SI0941100T1 - Pharmaceutical compositions containing lamivudine and zidovudine - Google Patents

Pharmaceutical compositions containing lamivudine and zidovudine

Info

Publication number: SI0941100T1
Authority: SI; Slovenia
Prior art keywords: zidovudine; pharmaceutical compositions; compositions containing; containing lamivudine; lamivudine
Prior art date: 1996-10-31

Application number

SI9730570T

Other languages

English (en)

Slovenian (sl)

Inventor

Gary Wayne Goodson

Allen Wayne Wood

Katherine Jeannette Ford

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-31

Filing date

1997-10-29

Publication date

2003-12-31

1997-10-29 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2003-12-31 Publication of SI0941100T1 publication Critical patent/SI0941100T1/xx

Links

LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Immunology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

SI9730570T 1996-10-31 1997-10-29 Pharmaceutical compositions containing lamivudine and zidovudine SI0941100T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9622681.6A GB9622681D0 (en)	1996-10-31	1996-10-31	Pharmaceutical compositions
EP97950036A EP0941100B1 (en)	1996-10-31	1997-10-29	Pharmaceutical compositions containing lamivudine and zidovudine
PCT/EP1997/005953 WO1998018477A2 (en)	1996-10-31	1997-10-29	Pharmaceutical compositions containing lamivudine and zidovudine

Publications (1)

Publication Number	Publication Date
SI0941100T1 true SI0941100T1 (en)	2003-12-31

Family

ID=10802224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9730570T SI0941100T1 (en)	1996-10-31	1997-10-29	Pharmaceutical compositions containing lamivudine and zidovudine

Country Status (43)

Country	Link
EP (1)	EP0941100B1 (xx)
JP (1)	JP2001502718A (xx)
KR (1)	KR100551652B1 (xx)
AP (1)	AP1067A (xx)
AR (1)	AR009135A1 (xx)
AT (1)	ATE241364T1 (xx)
AU (1)	AU736607B2 (xx)
BG (1)	BG64541B1 (xx)
BR (1)	BR9712614A (xx)
CA (1)	CA2270174A1 (xx)
CO (1)	CO4930269A1 (xx)
CY (1)	CY2485B1 (xx)
CZ (1)	CZ296080B6 (xx)
DE (1)	DE69722433T2 (xx)
DK (1)	DK0941100T3 (xx)
EA (1)	EA002437B1 (xx)
EE (1)	EE03806B1 (xx)
ES (1)	ES2200204T3 (xx)
GB (1)	GB9622681D0 (xx)
GE (1)	GEP20022735B (xx)
GT (1)	GT199700116A (xx)
HR (1)	HRP970569B1 (xx)
HU (1)	HU224969B1 (xx)
ID (1)	ID18698A (xx)
IL (1)	IL129422A0 (xx)
IS (1)	IS5024A (xx)
MY (1)	MY119513A (xx)
NO (1)	NO317163B1 (xx)
NZ (1)	NZ335153A (xx)
OA (1)	OA11038A (xx)
PA (1)	PA8441101A1 (xx)
PE (1)	PE10099A1 (xx)
PL (1)	PL190349B1 (xx)
PT (1)	PT941100E (xx)
SI (1)	SI0941100T1 (xx)
SK (1)	SK284286B6 (xx)
SV (1)	SV1997000090A (xx)
TR (1)	TR199900950T2 (xx)
UA (1)	UA64725C2 (xx)
UY (1)	UY24766A1 (xx)
WO (1)	WO1998018477A2 (xx)
YU (1)	YU19999A (xx)
ZA (1)	ZA979726B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions
GB9809213D0 (en) *	1998-04-29	1998-07-01	Glaxo Group Ltd	Pharmaceutical compositions
US7074417B2 (en) *	2000-10-13	2006-07-11	Advancis Pharmaceutical Corporation	Multiple-delayed release anti-viral product, use and formulation thereof
US20050175694A1 (en) *	2002-04-23	2005-08-11	Himadri Sen	Long acting compositions comprising zidovudine and lamivudine
ATE361059T1 (de) *	2002-11-08	2007-05-15	Glaxo Group Ltd	Antivirale zusammensetzungen
JP4996241B2 (ja)	2003-01-14	2012-08-08	ギリアードサイエンシーズ，インコーポレイテッド	組み合わせ抗ウイルス治療のための組成物および方法
AR045841A1 (es) *	2004-09-28	2005-11-16	Richmond Sa Com Ind Y Financie	Una composicion farmaceutica solida que comprende al tiazolil metil ester del acido [5s-(5r, 8r, 10r,11r)] -10- hidroxi-2- metil-5-(1-metiletil)-1-[2-(1-metiletil)-4-tiazolil]-3,6-dioxo-8,11-bis(fenilmetil)-2,4,7,12- tetraazatridecan-13-oico y un procedimiento para prepararla.
CN114010776A (zh)	2010-06-09	2022-02-08	疫苗技术股份有限公司	用于增强抗逆转录病毒治疗的hiv感染者的治疗性免疫
CA2866133A1 (en)	2012-03-05	2013-09-12	Cipla Limited	Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine
US20140234415A1 (en) *	2013-02-20	2014-08-21	Abbvie Inc.	Tablet Dosage Forms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4950652A (en) *	1987-03-23	1990-08-21	Hem Research, Inc.	dsRNAs for combination therapy in the treatment of viral diseases
GB9110624D0 (en) *	1991-05-16	1991-07-03	Glaxo Group Ltd	Combinations
DE69206876T3 (de) *	1991-05-16	2004-08-12	Glaxo Group Ltd., Greenford	Nukleosidanalogen enthaltende Antiviren-Zubereitungen
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions

1996
- 1996-10-31 GB GBGB9622681.6A patent/GB9622681D0/en active Pending
1997
- 1997-10-24 HR HR970569A patent/HRP970569B1/xx not_active IP Right Cessation
- 1997-10-28 CO CO97063174A patent/CO4930269A1/es unknown
- 1997-10-28 SV SV1997000090A patent/SV1997000090A/es not_active Application Discontinuation
- 1997-10-28 MY MYPI97005103A patent/MY119513A/en unknown
- 1997-10-29 AR ARP970105027A patent/AR009135A1/es unknown
- 1997-10-29 EP EP97950036A patent/EP0941100B1/en not_active Expired - Lifetime
- 1997-10-29 GT GT199700116A patent/GT199700116A/es unknown
- 1997-10-29 DE DE69722433T patent/DE69722433T2/de not_active Expired - Lifetime
- 1997-10-29 CZ CZ0155799A patent/CZ296080B6/cs not_active IP Right Cessation
- 1997-10-29 JP JP10520045A patent/JP2001502718A/ja active Pending
- 1997-10-29 DK DK97950036T patent/DK0941100T3/da active
- 1997-10-29 TR TR1999/00950T patent/TR199900950T2/xx unknown
- 1997-10-29 SI SI9730570T patent/SI0941100T1/xx unknown
- 1997-10-29 PE PE1997000965A patent/PE10099A1/es not_active Application Discontinuation
- 1997-10-29 YU YU19999A patent/YU19999A/sh unknown
- 1997-10-29 HU HU0000344A patent/HU224969B1/hu not_active IP Right Cessation
- 1997-10-29 IL IL12942297A patent/IL129422A0/xx not_active IP Right Cessation
- 1997-10-29 SK SK575-99A patent/SK284286B6/sk unknown
- 1997-10-29 KR KR1019997003757A patent/KR100551652B1/ko not_active Expired - Fee Related
- 1997-10-29 GE GEAP19974781A patent/GEP20022735B/en unknown
- 1997-10-29 EA EA199900345A patent/EA002437B1/ru not_active IP Right Cessation
- 1997-10-29 ES ES97950036T patent/ES2200204T3/es not_active Expired - Lifetime
- 1997-10-29 PL PL97333143A patent/PL190349B1/pl unknown
- 1997-10-29 AT AT97950036T patent/ATE241364T1/de active
- 1997-10-29 AP APAP/P/1999/001519A patent/AP1067A/en active
- 1997-10-29 EE EEP199900175A patent/EE03806B1/xx not_active IP Right Cessation
- 1997-10-29 BR BR9712614-4A patent/BR9712614A/pt not_active IP Right Cessation
- 1997-10-29 AU AU53142/98A patent/AU736607B2/en not_active Ceased
- 1997-10-29 NZ NZ335153A patent/NZ335153A/en unknown
- 1997-10-29 CA CA002270174A patent/CA2270174A1/en not_active Abandoned
- 1997-10-29 UA UA99042239A patent/UA64725C2/uk unknown
- 1997-10-29 PT PT97950036T patent/PT941100E/pt unknown
- 1997-10-29 ZA ZA979726A patent/ZA979726B/xx unknown
- 1997-10-29 WO PCT/EP1997/005953 patent/WO1998018477A2/en not_active Ceased
- 1997-10-30 UY UY24766A patent/UY24766A1/es not_active IP Right Cessation
- 1997-10-30 PA PA19978441101A patent/PA8441101A1/es unknown
- 1997-10-30 ID IDP973554A patent/ID18698A/id unknown
1999
- 1999-04-09 IS IS5024A patent/IS5024A/is unknown
- 1999-04-23 OA OA9900088A patent/OA11038A/en unknown
- 1999-04-29 NO NO19992091A patent/NO317163B1/no unknown
- 1999-05-26 BG BG103435A patent/BG64541B1/bg unknown
2004
- 2004-11-26 CY CY0400085A patent/CY2485B1/xx unknown

Also Published As

Publication number	Publication date
DE69722433T2 (de)	2004-04-08
PE10099A1 (es)	1999-03-02
ATE241364T1 (de)	2003-06-15
IL129422A0 (en)	2000-02-17
NO317163B1 (no)	2004-08-30
CA2270174A1 (en)	1998-05-07
GB9622681D0 (en)	1997-01-08
SK284286B6 (sk)	2005-01-03
PA8441101A1 (es)	2000-05-24
NO992091D0 (no)	1999-04-29
HK1020880A1 (en)	2000-05-26
HUP0000344A3 (en)	2002-04-29
ID18698A (id)	1998-04-30
AU5314298A (en)	1998-05-22
GT199700116A (es)	1999-04-22
HUP0000344A2 (hu)	2001-05-28
PL190349B1 (pl)	2005-11-30
IS5024A (is)	1999-04-09
WO1998018477A3 (en)	1998-06-18
BR9712614A (pt)	1999-10-26
BG103435A (en)	2000-04-28
NZ335153A (en)	2001-04-27
UA64725C2 (uk)	2004-03-15
AP9901519A0 (en)	1999-06-30
WO1998018477A2 (en)	1998-05-07
DK0941100T3 (da)	2003-09-01
UY24766A1 (es)	2000-12-29
OA11038A (en)	2002-02-06
HRP970569B1 (en)	2004-10-31
AP1067A (en)	2002-05-01
YU19999A (sh)	2000-10-30
CY2485B1 (en)	2005-06-03
KR20000052893A (ko)	2000-08-25
TR199900950T2 (xx)	1999-07-21
JP2001502718A (ja)	2001-02-27
DE69722433D1 (de)	2003-07-03
HRP970569A2 (en)	1998-08-31
SV1997000090A (es)	1998-10-07
AR009135A1 (es)	2000-03-08
PT941100E (pt)	2003-10-31
BG64541B1 (bg)	2005-07-29
NO992091L (no)	1999-06-29
EP0941100B1 (en)	2003-05-28
EP0941100A2 (en)	1999-09-15
CZ155799A3 (cs)	1999-10-13
EE03806B1 (et)	2002-08-15
EA002437B1 (ru)	2002-04-25
ZA979726B (en)	1999-04-29
MY119513A (en)	2005-06-30
SK57599A3 (en)	2000-06-12
AU736607B2 (en)	2001-08-02
CO4930269A1 (es)	2000-06-27
GEP20022735B (en)	2002-07-25
EE9900175A (et)	1999-12-15
ES2200204T3 (es)	2004-03-01
EA199900345A1 (ru)	2000-02-28
PL333143A1 (en)	1999-11-22
CZ296080B6 (cs)	2006-01-11
KR100551652B1 (ko)	2006-02-13
HU224969B1 (en)	2006-04-28

Publication	Publication Date	Title
IL114622A0 (en)	1995-11-27	Heteroaryl-oxazolidinones and pharmaceutical compositions containing them
IL121236A0 (en)	1998-01-04	Cycloalkano-pyridines their preparation and pharmaceutical compositions containing them
IL191904A0 (en)	2008-12-29	Pharmaceutical and compositions containing a?? fragments
HUP0001309A3 (en)	2000-12-28	1-phenyl-4-benzylpiperazines and pharmaceutical compositions containing them
HUP9802999A3 (en)	1999-05-28	Pharmaceutical composition containing n-propargyl-1-aminoindan
PL336840A1 (en)	2000-07-17	Hair-care composition
PL335870A1 (en)	2000-05-22	Hair-care composition
IL135646A0 (en)	2001-05-20	α-ARYL-N-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
HUP9900424A2 (hu)	1999-05-28	Tiazolil-benzfurán-származékok és a vegyületeket tartalmazó gyógyászati készítmények
HUP9901452A3 (en)	2001-02-28	Bicyclic-aromatic compounds and pharmaceutical compositions containing them
IL128058A0 (en)	1999-11-30	Illudin analogs and pharmaceutical compositions containing the same
EP0968983A4 (en)	2000-09-27	COMPOSITION BASED ON HEXANITROHEXAAZAISOWURTIZITAN AND HEXANITROHEXAAZAISOWURTIZITAN COMPOSITION OF EXPLOSIVES
PL331423A1 (en)	1999-07-19	Muporocin and chlorohexidrin containing compositions
IL117623A (en)	2000-01-31	Maltitol composition and its preparation
HUP0101701A3 (en)	2003-02-28	Substituted betha-alanines and pharmaceutical compositions comprising them
IL116015A0 (en)	1996-01-31	Iminooxymethyleneanilides thdir preparation and compositions containing them
IL133928A0 (en)	2001-04-30	Pharmaceutical composition containing peptichemio
HUP0000344A3 (en)	2002-04-29	Pharmaceutical compositions containing lamivudine and zidovudine
IL131917A (en)	2001-01-11	Pharmaceutical compositions containing lamivudine
HUP0000460A3 (en)	2001-04-28	Imidazopyridazines and pharmaceutical compositions thereof
IL112564A0 (en)	1995-05-26	1-beta-methyl-carbapenems and compositions containing them
GB9623962D0 (en)	1997-01-08	Pharmaceutical composition
IL115882A0 (en)	1996-01-31	Oxazolyl-and thiazolylimidazo-benzo-and thienodiazepines their manufacture and pharmaceutical compositions containing them
HUP0000275A3 (en)	2001-12-28	Phenanethridinium derivatives and pharmaceutical compositions containing them
HUP9901968A3 (en)	2000-01-28	2-thioxotetrahydropyrimidin-4-one derivatives and pharmaceutical compositions containing them