EE03806B1 - Lamivudiini ja sidovudiini sisaldavad farmatseutilised kompositsioonid - Google Patents

Lamivudiini ja sidovudiini sisaldavad farmatseutilised kompositsioonid

Info

Publication number: EE03806B1
Authority: EE; Estonia
Prior art keywords: zidovudine; pharmaceutical compositions; compositions containing; containing lamivudine; lamivudine
Prior art date: 1996-10-31

Application number

EEP199900175A

Other languages

English (en)

Estonian (et)

Other versions

EE9900175A (et

Inventor

Wayne Goodson Gary

Wayne Wood Allen

Jeannette Ford Katherine

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-31

Filing date

1997-10-29

Publication date

2002-08-15

1997-10-29 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

1999-12-15 Publication of EE9900175A publication Critical patent/EE9900175A/xx

2002-08-15 Publication of EE03806B1 publication Critical patent/EE03806B1/xx

Links

LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
Biotechnology (AREA)
AIDS & HIV (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

EEP199900175A 1996-10-31 1997-10-29 Lamivudiini ja sidovudiini sisaldavad farmatseutilised kompositsioonid EE03806B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9622681.6A GB9622681D0 (en)	1996-10-31	1996-10-31	Pharmaceutical compositions
PCT/EP1997/005953 WO1998018477A2 (en)	1996-10-31	1997-10-29	Pharmaceutical compositions containing lamivudine and zidovudine

Publications (2)

Publication Number	Publication Date
EE9900175A EE9900175A (et)	1999-12-15
EE03806B1 true EE03806B1 (et)	2002-08-15

Family

ID=10802224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900175A EE03806B1 (et)	1996-10-31	1997-10-29	Lamivudiini ja sidovudiini sisaldavad farmatseutilised kompositsioonid

Country Status (43)

Country	Link
EP (1)	EP0941100B1 (xx)
JP (1)	JP2001502718A (xx)
KR (1)	KR100551652B1 (xx)
AP (1)	AP1067A (xx)
AR (1)	AR009135A1 (xx)
AT (1)	ATE241364T1 (xx)
AU (1)	AU736607B2 (xx)
BG (1)	BG64541B1 (xx)
BR (1)	BR9712614A (xx)
CA (1)	CA2270174A1 (xx)
CO (1)	CO4930269A1 (xx)
CY (1)	CY2485B1 (xx)
CZ (1)	CZ296080B6 (xx)
DE (1)	DE69722433T2 (xx)
DK (1)	DK0941100T3 (xx)
EA (1)	EA002437B1 (xx)
EE (1)	EE03806B1 (xx)
ES (1)	ES2200204T3 (xx)
GB (1)	GB9622681D0 (xx)
GE (1)	GEP20022735B (xx)
GT (1)	GT199700116A (xx)
HR (1)	HRP970569B1 (xx)
HU (1)	HU224969B1 (xx)
ID (1)	ID18698A (xx)
IL (1)	IL129422A0 (xx)
IS (1)	IS5024A (xx)
MY (1)	MY119513A (xx)
NO (1)	NO317163B1 (xx)
NZ (1)	NZ335153A (xx)
OA (1)	OA11038A (xx)
PA (1)	PA8441101A1 (xx)
PE (1)	PE10099A1 (xx)
PL (1)	PL190349B1 (xx)
PT (1)	PT941100E (xx)
SI (1)	SI0941100T1 (xx)
SK (1)	SK284286B6 (xx)
SV (1)	SV1997000090A (xx)
TR (1)	TR199900950T2 (xx)
UA (1)	UA64725C2 (xx)
UY (1)	UY24766A1 (xx)
WO (1)	WO1998018477A2 (xx)
YU (1)	YU19999A (xx)
ZA (1)	ZA979726B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions
GB9809213D0 (en) *	1998-04-29	1998-07-01	Glaxo Group Ltd	Pharmaceutical compositions
US7074417B2 (en) *	2000-10-13	2006-07-11	Advancis Pharmaceutical Corporation	Multiple-delayed release anti-viral product, use and formulation thereof
US20050175694A1 (en) *	2002-04-23	2005-08-11	Himadri Sen	Long acting compositions comprising zidovudine and lamivudine
WO2004043433A2 (en) *	2002-11-08	2004-05-27	Glaxo Group Limited	Pharmaceutical antiviral compositions
US20040224917A1 (en)	2003-01-14	2004-11-11	Gilead Sciences, Inc.	Compositions and methods for combination antiviral therapy
AR045841A1 (es) *	2004-09-28	2005-11-16	Richmond Sa Com Ind Y Financie	Una composicion farmaceutica solida que comprende al tiazolil metil ester del acido [5s-(5r, 8r, 10r,11r)] -10- hidroxi-2- metil-5-(1-metiletil)-1-[2-(1-metiletil)-4-tiazolil]-3,6-dioxo-8,11-bis(fenilmetil)-2,4,7,12- tetraazatridecan-13-oico y un procedimiento para prepararla.
EP2579892A2 (en)	2010-06-09	2013-04-17	Vaccine Technologies, Incorporated	Therapeutic immunization in hiv infected subjects receiving stable antiretroviral treatment
CA2866133A1 (en)	2012-03-05	2013-09-12	Cipla Limited	Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine
WO2014130553A2 (en) *	2013-02-20	2014-08-28	Abbvie Inc.	Tablet dosage forms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4950652A (en) *	1987-03-23	1990-08-21	Hem Research, Inc.	dsRNAs for combination therapy in the treatment of viral diseases
DK0513917T4 (da) *	1991-05-16	2001-06-25	Glaxo Group Ltd	Antivirale kombinationer indeholdende nukleosidanaloger
GB9110624D0 (en) *	1991-05-16	1991-07-03	Glaxo Group Ltd	Combinations
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions

1996
- 1996-10-31 GB GBGB9622681.6A patent/GB9622681D0/en active Pending
1997
- 1997-10-24 HR HR970569A patent/HRP970569B1/xx not_active IP Right Cessation
- 1997-10-28 MY MYPI97005103A patent/MY119513A/en unknown
- 1997-10-28 CO CO97063174A patent/CO4930269A1/es unknown
- 1997-10-28 SV SV1997000090A patent/SV1997000090A/es not_active Application Discontinuation
- 1997-10-29 AU AU53142/98A patent/AU736607B2/en not_active Ceased
- 1997-10-29 HU HU0000344A patent/HU224969B1/hu not_active IP Right Cessation
- 1997-10-29 AT AT97950036T patent/ATE241364T1/de active
- 1997-10-29 WO PCT/EP1997/005953 patent/WO1998018477A2/en not_active Ceased
- 1997-10-29 AR ARP970105027A patent/AR009135A1/es unknown
- 1997-10-29 GT GT199700116A patent/GT199700116A/es unknown
- 1997-10-29 GE GEAP19974781A patent/GEP20022735B/en unknown
- 1997-10-29 EE EEP199900175A patent/EE03806B1/xx not_active IP Right Cessation
- 1997-10-29 UA UA99042239A patent/UA64725C2/uk unknown
- 1997-10-29 CZ CZ0155799A patent/CZ296080B6/cs not_active IP Right Cessation
- 1997-10-29 PL PL97333143A patent/PL190349B1/pl unknown
- 1997-10-29 TR TR1999/00950T patent/TR199900950T2/xx unknown
- 1997-10-29 BR BR9712614-4A patent/BR9712614A/pt not_active IP Right Cessation
- 1997-10-29 EP EP97950036A patent/EP0941100B1/en not_active Expired - Lifetime
- 1997-10-29 PT PT97950036T patent/PT941100E/pt unknown
- 1997-10-29 ZA ZA979726A patent/ZA979726B/xx unknown
- 1997-10-29 EA EA199900345A patent/EA002437B1/ru not_active IP Right Cessation
- 1997-10-29 KR KR1019997003757A patent/KR100551652B1/ko not_active Expired - Fee Related
- 1997-10-29 NZ NZ335153A patent/NZ335153A/en unknown
- 1997-10-29 CA CA002270174A patent/CA2270174A1/en not_active Abandoned
- 1997-10-29 ES ES97950036T patent/ES2200204T3/es not_active Expired - Lifetime
- 1997-10-29 DK DK97950036T patent/DK0941100T3/da active
- 1997-10-29 SK SK575-99A patent/SK284286B6/sk unknown
- 1997-10-29 DE DE69722433T patent/DE69722433T2/de not_active Expired - Lifetime
- 1997-10-29 SI SI9730570T patent/SI0941100T1/xx unknown
- 1997-10-29 AP APAP/P/1999/001519A patent/AP1067A/en active
- 1997-10-29 YU YU19999A patent/YU19999A/sh unknown
- 1997-10-29 IL IL12942297A patent/IL129422A0/xx not_active IP Right Cessation
- 1997-10-29 JP JP10520045A patent/JP2001502718A/ja active Pending
- 1997-10-29 PE PE1997000965A patent/PE10099A1/es not_active Application Discontinuation
- 1997-10-30 ID IDP973554A patent/ID18698A/id unknown
- 1997-10-30 UY UY24766A patent/UY24766A1/es not_active IP Right Cessation
- 1997-10-30 PA PA19978441101A patent/PA8441101A1/es unknown
1999
- 1999-04-09 IS IS5024A patent/IS5024A/is unknown
- 1999-04-23 OA OA9900088A patent/OA11038A/en unknown
- 1999-04-29 NO NO19992091A patent/NO317163B1/no unknown
- 1999-05-26 BG BG103435A patent/BG64541B1/bg unknown
2004
- 2004-11-26 CY CY0400085A patent/CY2485B1/xx unknown

Also Published As

Publication number	Publication date
IS5024A (is)	1999-04-09
IL129422A0 (en)	2000-02-17
HK1020880A1 (en)	2000-05-26
SK284286B6 (sk)	2005-01-03
SI0941100T1 (en)	2003-12-31
NZ335153A (en)	2001-04-27
CO4930269A1 (es)	2000-06-27
DE69722433T2 (de)	2004-04-08
HRP970569B1 (en)	2004-10-31
AU736607B2 (en)	2001-08-02
EP0941100B1 (en)	2003-05-28
PT941100E (pt)	2003-10-31
AR009135A1 (es)	2000-03-08
PL333143A1 (en)	1999-11-22
UY24766A1 (es)	2000-12-29
NO317163B1 (no)	2004-08-30
BG64541B1 (bg)	2005-07-29
EA002437B1 (ru)	2002-04-25
PL190349B1 (pl)	2005-11-30
HRP970569A2 (en)	1998-08-31
HUP0000344A3 (en)	2002-04-29
NO992091D0 (no)	1999-04-29
TR199900950T2 (xx)	1999-07-21
ES2200204T3 (es)	2004-03-01
AU5314298A (en)	1998-05-22
BR9712614A (pt)	1999-10-26
WO1998018477A3 (en)	1998-06-18
ID18698A (id)	1998-04-30
GT199700116A (es)	1999-04-22
OA11038A (en)	2002-02-06
EE9900175A (et)	1999-12-15
WO1998018477A2 (en)	1998-05-07
CY2485B1 (en)	2005-06-03
PA8441101A1 (es)	2000-05-24
GEP20022735B (en)	2002-07-25
BG103435A (en)	2000-04-28
SK57599A3 (en)	2000-06-12
AP9901519A0 (en)	1999-06-30
GB9622681D0 (en)	1997-01-08
KR100551652B1 (ko)	2006-02-13
ATE241364T1 (de)	2003-06-15
DE69722433D1 (de)	2003-07-03
NO992091L (no)	1999-06-29
JP2001502718A (ja)	2001-02-27
ZA979726B (en)	1999-04-29
YU19999A (sh)	2000-10-30
CZ296080B6 (cs)	2006-01-11
UA64725C2 (uk)	2004-03-15
AP1067A (en)	2002-05-01
DK0941100T3 (da)	2003-09-01
EA199900345A1 (ru)	2000-02-28
KR20000052893A (ko)	2000-08-25
MY119513A (en)	2005-06-30
EP0941100A2 (en)	1999-09-15
CA2270174A1 (en)	1998-05-07
CZ155799A3 (cs)	1999-10-13
HUP0000344A2 (hu)	2001-05-28
HU224969B1 (en)	2006-04-28
SV1997000090A (es)	1998-10-07
PE10099A1 (es)	1999-03-02

Publication	Publication Date	Title
FI973475L (fi)	1999-02-23	Koostumus ja sitä sisältävä tuote
NO20002359L (no)	2000-07-05	Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene
NO962606L (no)	1996-12-23	Farmasöytisk sammensetning
CY2005007I1 (el)	2009-11-04	Φαρμακευτικες συνθεσεις που περιεχουν δαριφενακινη
ID18352A (id)	1998-04-02	Komposisi-komposisi farmasi
ID17774A (id)	1998-01-29	Komposisi farmasi antitrombosis
EE200000646A (et)	2002-04-15	Abakaviiri, lamivudiini ja zidovudiini sisaldavadhomogeensed farmatseutilised kompositsioonid
FI972434L (fi)	1997-06-09	Lamotrigiiniä sisältävä farmaseuttinen koostumus
EE03806B1 (et)	2002-08-15	Lamivudiini ja sidovudiini sisaldavad farmatseutilised kompositsioonid
BR9507768A (pt)	1997-09-02	Composição farmacêutica
ID29294A (id)	2001-08-16	Komposisi farmasi
LV11727A (lv)	1997-04-20	Farmaceitiska kompozicija
FI971427A7 (fi)	1997-05-26	Peptidit ja niitä sisältävät farmaseuttiset koostumukset
ID25857A (id)	2000-11-09	Komposisi farmasi
FI973280A7 (fi)	1997-08-08	Farmaseuttinen koostumus
ITMI962628A0 (it)	1996-12-16	Composizione farmaceutica
BR9605777A (pt)	1998-08-25	Composição farmacêutica
ID23531A (id)	2000-04-27	Komposisi farmasi
NO964309D0 (no)	1996-10-10	Farmasöytisk sammensetning
IT1272935B (it)	1997-07-01	Composizione farmaceutica contenente n-acetil-cisteina
BR1100391A (pt)	2002-04-09	Composto e composição farmacêutica
FI955181A7 (fi)	1995-10-30	Trymoktonaania ja ATZ:ä sisältävät farmaseuttiset koostumuset
SE9604299D0 (sv)	1996-11-22	Pharmaceutical composition
SE9601854D0 (sv)	1996-05-10	Farmaceutisk komposition
ID17133A (id)	1997-12-04	Komposisi farmasi

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2006-10-16	MA4A	Abandonment or withdrawal	Effective date: 20060815