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SG11201900609PA - Method and system for providing buffer solutions - Google Patents

Method and system for providing buffer solutions

Info

Publication number
SG11201900609PA
SG11201900609PA SG11201900609PA SG11201900609PA SG11201900609PA SG 11201900609P A SG11201900609P A SG 11201900609PA SG 11201900609P A SG11201900609P A SG 11201900609PA SG 11201900609P A SG11201900609P A SG 11201900609PA SG 11201900609P A SG11201900609P A SG 11201900609PA
Authority
SG
Singapore
Prior art keywords
international
processing solution
applicant
pct
rule
Prior art date
Application number
SG11201900609PA
Inventor
Tristan Wilkins
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of SG11201900609PA publication Critical patent/SG11201900609PA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/44Multiple separable units; Modules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M43/00Combinations of bioreactors or fermenters with other apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67DDISPENSING, DELIVERING OR TRANSFERRING LIQUIDS, NOT OTHERWISE PROVIDED FOR
    • B67D7/00Apparatus or devices for transferring liquids from bulk storage containers or reservoirs into vehicles or into portable containers, e.g. for retail sale purposes
    • B67D7/02Apparatus or devices for transferring liquids from bulk storage containers or reservoirs into vehicles or into portable containers, e.g. for retail sale purposes for transferring liquids other than fuel or lubricants
    • B67D7/0288Container connection means
    • B67D7/0294Combined with valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • General Factory Administration (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Forklifts And Lifting Vehicles (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

118 118 118 100 O cc O O (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 08 February 2018 (08.02.2018) WIPO I PCT °mons °nolo omolomoin Kuno Hs (10) International Publication Number WO 2018/026956 Al (51) International Patent Classification: C12M 1/00 (2006.01) BOIL 3/00 (2006.01) (21) International Application Number: PCT/US2017/045162 (22) International Filing Date: 02 August 2017 (02.08.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/370,041 02 August 2016 (02.08.2016) US (71) Applicant: LONZA LTD [CH/CH]; Lonzastrasse, 3930 Visp (CH). (72) Inventor; and (71) Applicant (for US only): WILKINS, Tristan [US/US]; 14 Barberry Coast Road, Newmarket, NH 03857 (US). (74) Agent: COLLAZO, Diana, M. et al.; Lando & Anastasi, LLP, Riverfront Office Park, One Main Street, Suite 1100, Cambridge, MA 02142 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (54) Title: METHOD AND SYSTEM FOR PROVIDING BUFFER SOLUTIONS (57) : A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site. The method also includes combining the concentrated processing solution with a biopolymer containing solution produced in a bioreactor at a second site different from the first site. In some embodiments, the processing solution is a buffer for processing products of cells cultured in a bioreactor. A system and a pharmaceutical production facility for carrying out the method is also provided. [Continued on next page] WO 2018/026956 Al IMEDIMOMMIDIRE10101011010HEIHRIMMOIMIE MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(11)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3))
SG11201900609PA 2016-08-02 2017-08-02 Method and system for providing buffer solutions SG11201900609PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662370041P 2016-08-02 2016-08-02
PCT/US2017/045162 WO2018026956A1 (en) 2016-08-02 2017-08-02 Method and system for providing buffer solutions

Publications (1)

Publication Number Publication Date
SG11201900609PA true SG11201900609PA (en) 2019-02-27

Family

ID=59593161

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201900528PA SG11201900528PA (en) 2016-08-02 2017-07-25 Customizable facility
SG11201900609PA SG11201900609PA (en) 2016-08-02 2017-08-02 Method and system for providing buffer solutions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201900528PA SG11201900528PA (en) 2016-08-02 2017-07-25 Customizable facility

Country Status (8)

Country Link
US (4) US10669518B2 (en)
EP (2) EP3478821A1 (en)
JP (5) JP2019525765A (en)
KR (5) KR102423233B1 (en)
CN (2) CN109715782A (en)
IL (4) IL307217A (en)
SG (2) SG11201900528PA (en)
WO (2) WO2018026577A1 (en)

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Also Published As

Publication number Publication date
US20250320446A1 (en) 2025-10-16
IL264373A (en) 2019-02-28
KR102423233B9 (en) 2024-08-22
JP3239085U (en) 2022-09-13
JP2024144457A (en) 2024-10-11
US12371650B2 (en) 2025-07-29
US20200283718A1 (en) 2020-09-10
WO2018026956A1 (en) 2018-02-08
JP7526756B2 (en) 2024-08-01
JP2019524125A (en) 2019-09-05
WO2018026577A1 (en) 2018-02-08
IL264373B1 (en) 2023-11-01
IL307847B1 (en) 2025-07-01
IL264374B2 (en) 2024-03-01
KR102423233B1 (en) 2022-07-19
IL307847B2 (en) 2025-11-01
SG11201900528PA (en) 2019-02-27
IL307847A (en) 2023-12-01
JP2019525765A (en) 2019-09-12
KR102480770B1 (en) 2022-12-22
US20240132830A1 (en) 2024-04-25
KR20220104297A (en) 2022-07-26
KR20190037288A (en) 2019-04-05
IL307217A (en) 2023-11-01
IL264374A (en) 2019-02-28
KR102807585B1 (en) 2025-05-15
JP7075927B2 (en) 2022-05-26
US11898137B2 (en) 2024-02-13
US10669518B2 (en) 2020-06-02
KR20250069976A (en) 2025-05-20
CN109715778A (en) 2019-05-03
US20180037861A1 (en) 2018-02-08
KR20220114091A (en) 2022-08-17
IL264374B1 (en) 2023-11-01
EP3478817A1 (en) 2019-05-08
JP2022097744A (en) 2022-06-30
EP3478821A1 (en) 2019-05-08
IL264373B2 (en) 2024-03-01
KR20190037289A (en) 2019-04-05
CN109715782A (en) 2019-05-03

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