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SG11201403041TA - Apparatus, system and method for identifying circulating tumor cells - Google Patents

Apparatus, system and method for identifying circulating tumor cells

Info

Publication number
SG11201403041TA
SG11201403041TA SG11201403041TA SG11201403041TA SG11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA
Authority
SG
Singapore
Prior art keywords
tumor cells
circulating tumor
identifying circulating
identifying
cells
Prior art date
Application number
SG11201403041TA
Inventor
Peter Kuhn
Anand Kolatkar
Gerd Marienfeld
Dena Marrinucci
Original Assignee
Scripps Research Inst
Gerd Marienfeld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Gerd Marienfeld filed Critical Scripps Research Inst
Publication of SG11201403041TA publication Critical patent/SG11201403041TA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/4833Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0822Slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Multimedia (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Oncology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
SG11201403041TA 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells SG11201403041TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568793P 2011-12-09 2011-12-09
PCT/US2012/068586 WO2013086428A1 (en) 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells

Publications (1)

Publication Number Publication Date
SG11201403041TA true SG11201403041TA (en) 2014-08-28

Family

ID=48574948

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201403041TA SG11201403041TA (en) 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells

Country Status (14)

Country Link
US (1) US20140329917A1 (en)
EP (1) EP2788773A4 (en)
JP (1) JP2015505966A (en)
KR (1) KR20150008842A (en)
CN (1) CN104428677A (en)
AU (1) AU2012347526A1 (en)
BR (1) BR112014013956A2 (en)
CA (1) CA2858689A1 (en)
EA (1) EA201491140A1 (en)
HK (1) HK1201916A1 (en)
IL (1) IL233007A0 (en)
MX (1) MX2014006884A (en)
SG (1) SG11201403041TA (en)
WO (1) WO2013086428A1 (en)

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US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
DK3290530T3 (en) 2009-02-18 2020-12-07 Streck Inc PRESERVATION OF CELL-FREE NUCLEIC ACIDS
CN107422127A (en) 2009-10-21 2017-12-01 斯克里普斯研究所 With the method for non-rare cell detection rare cell
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
US9396532B2 (en) * 2012-11-15 2016-07-19 Siemens Healthcare Diagnostics, Inc. Cell feature-based automatic circulating tumor cell detection
CA2917912C (en) 2013-07-24 2019-09-17 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US9683938B2 (en) 2013-07-31 2017-06-20 The Regents Of The University Of California Fluorescent imaging using a flatbed scanner
EP3967770B1 (en) * 2013-10-21 2023-12-06 The General Hospital Corporation Methods relating to circulating tumor cell clusters and the treatment of cancer
WO2015112955A1 (en) 2014-01-27 2015-07-30 Epic Sciences, Inc. Circulating tumor cell diagnostics for prostate cancer biomarkers
EA201691505A1 (en) * 2014-01-27 2016-12-30 Эпик Сайенсиз, Инк. DETECTION OF EXPRESSION OF PROSTATIC SPECIFIC MEMBRANE ANTIGEN (PSMA) ON CIRCULATING TUMOR CELLS (CTC)
ES2868077T3 (en) * 2014-01-30 2021-10-21 Epic Sciences Inc Diagnosis using circulating tumor cells for predictive biomarkers of resistance to selective androgen receptor (AR) therapies
US10545151B2 (en) 2014-02-21 2020-01-28 Epic Sciences, Inc. Methods for analyzing rare circulating cells
CN104062428B (en) * 2014-07-09 2016-08-17 郑勤 A kind of test kit detecting circulating tumor cell
US20180127829A1 (en) * 2014-12-10 2018-05-10 Board Of Regents, The University Of Texas System Circulating tumor and tumor stem cell detection using genomic specific probes
US20160178630A1 (en) * 2014-12-18 2016-06-23 Creatv Microtech, Inc. Methods for predicting overall survival of cancer patients based on numbers of circulating tumor cells
EP3252469A4 (en) * 2015-01-29 2017-12-06 Konica Minolta, Inc. Method for simultaneous detection of blood cells having interacting molecules
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
JP6815331B2 (en) * 2015-04-21 2021-01-20 ジェネンテック, インコーポレイテッド Compositions and Methods for Prostate Cancer Analysis
US20180313842A1 (en) * 2015-05-14 2018-11-01 The Board Of Trustees Of The University Of Illinois Method for monitoring efficacy of a cancer therapy using circulating tumor cells as a biomarker
EP3315594B1 (en) * 2015-06-24 2020-02-26 Hitachi, Ltd. Inspection system
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
CN107873050A (en) * 2016-07-25 2018-04-03 株式会社奥普特尼克斯精密 Slide preparation of specimen device, the slide Slide processing of cell and the DNA or RNA extracting method of cell
US11506655B2 (en) 2016-07-29 2022-11-22 Streck, Inc. Suspension composition for hematology analysis control
US20200088731A1 (en) * 2016-12-22 2020-03-19 Hitachi Chemical Company, Ltd. Method for Detecting HER2-Positive Cancer Cells
US9738937B1 (en) * 2017-03-31 2017-08-22 Cellmax, Ltd. Identifying candidate cells using image analysis
IT201700085439A1 (en) * 2017-07-26 2019-01-26 Tethis S P A METHOD OF IMMOBILIZATION OF BIOLOGICAL SAMPLES FOR ANALYTICAL AND DIAGNOSTIC PURPOSE
EP4427588A3 (en) 2017-10-19 2024-10-16 Streck LLC Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles
JP6485576B2 (en) * 2018-04-19 2019-03-20 日立化成株式会社 Standard cell solution
CN109887542A (en) * 2019-02-12 2019-06-14 嘉兴海云惠智医疗科技有限公司 A kind of tumour individuation genetic test intelligence solution read apparatus based on cloud computing
CN110146704A (en) * 2019-03-28 2019-08-20 苏州举健生物科技有限公司 A kind of medication and pathological examination data system based on circulating tumor cell
JP2021110664A (en) * 2020-01-14 2021-08-02 学校法人杏林学園 Method of predicting prognosis of cancer subject
CN111323362A (en) * 2020-03-17 2020-06-23 宁波江丰生物信息技术有限公司 Circulating tumor cell detection system and method based on fluorescence section
CN114092934A (en) * 2020-07-31 2022-02-25 骏实生物科技(上海)有限公司 Method for classifying circulating tumor cells

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Also Published As

Publication number Publication date
WO2013086428A1 (en) 2013-06-13
JP2015505966A (en) 2015-02-26
AU2012347526A1 (en) 2014-07-10
CA2858689A1 (en) 2013-06-13
US20140329917A1 (en) 2014-11-06
KR20150008842A (en) 2015-01-23
EP2788773A1 (en) 2014-10-15
IL233007A0 (en) 2014-07-31
MX2014006884A (en) 2015-06-02
CN104428677A (en) 2015-03-18
BR112014013956A2 (en) 2017-06-13
HK1201916A1 (en) 2015-09-11
EP2788773A4 (en) 2015-09-09
EA201491140A1 (en) 2014-11-28

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