SG10201913045PA - A solid state form of pladienolide pyridine compounds and methods of use - Google Patents
A solid state form of pladienolide pyridine compounds and methods of useInfo
- Publication number
- SG10201913045PA SG10201913045PA SG10201913045PA SG10201913045PA SG10201913045PA SG 10201913045P A SG10201913045P A SG 10201913045PA SG 10201913045P A SG10201913045P A SG 10201913045PA SG 10201913045P A SG10201913045P A SG 10201913045PA SG 10201913045P A SG10201913045P A SG 10201913045PA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- solid state
- state form
- pyridine compounds
- pladienolide pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562257088P | 2015-11-18 | 2015-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201913045PA true SG10201913045PA (en) | 2020-02-27 |
Family
ID=57472076
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913045PA SG10201913045PA (en) | 2015-11-18 | 2016-11-17 | A solid state form of pladienolide pyridine compounds and methods of use |
| SG11201803519YA SG11201803519YA (en) | 2015-11-18 | 2016-11-17 | A solid state form of pladienolide pyridine compounds and methods of use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201803519YA SG11201803519YA (en) | 2015-11-18 | 2016-11-17 | A solid state form of pladienolide pyridine compounds and methods of use |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10745387B2 (fr) |
| EP (1) | EP3377485B1 (fr) |
| JP (2) | JP6312282B2 (fr) |
| KR (1) | KR20180083376A (fr) |
| CN (1) | CN108473479B (fr) |
| AU (2) | AU2016357433B2 (fr) |
| BR (1) | BR112018009995B1 (fr) |
| CA (1) | CA3004623C (fr) |
| ES (1) | ES2757174T3 (fr) |
| IL (1) | IL259198B2 (fr) |
| MD (1) | MD3377485T2 (fr) |
| MX (2) | MX379655B (fr) |
| RU (2) | RU2743349C2 (fr) |
| SG (2) | SG10201913045PA (fr) |
| WO (1) | WO2017087667A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA128864C2 (uk) * | 2018-04-09 | 2024-11-13 | ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД. | Сполука пладієноліду та спосіб її застосування |
| EP3774760A1 (fr) | 2018-04-12 | 2021-02-17 | Eisai R&D Management Co., Ltd. | Dérivés de pladiénolide en tant qu'agents ciblant un complexe d'épissage pour le traitement du cancer |
| MX2020012940A (es) * | 2018-06-01 | 2021-03-25 | Eisai R&D Man Co Ltd | Metodos de uso de moduladores de empalme. |
| US20230022489A1 (en) * | 2019-12-04 | 2023-01-26 | Athma A. PAI | Identifying non-productive splice sites |
| MX2022015374A (es) * | 2020-06-05 | 2023-01-16 | Eisai R&D Man Co Ltd | Conjugados de anticuerpo anti antigeno de maduracion de linfocitos b (bcma)-farmaco y metodos de uso. |
| WO2022098712A1 (fr) | 2020-11-04 | 2022-05-12 | Eisai R&D Management Co., Ltd. | Biomarqueurs pour le syndrome myélodysplasique (mds) et leurs méthodes d'utilisation |
| WO2023131866A1 (fr) | 2022-01-05 | 2023-07-13 | Eisai R&D Management Co., Ltd. | Biomarqueurs pour le syndrome myélodysplasique (mds) et leurs méthodes d'utilisation |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI312681B (en) * | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| TWI334866B (en) | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| AU2003252299A1 (en) | 2002-07-31 | 2004-02-16 | Eisai Co., Ltd. | Novel physiologically active substance |
| NZ537830A (en) | 2002-07-31 | 2007-12-21 | Mercian Corp | Novel physiologically active substances |
| AU2003285012A1 (en) | 2002-10-24 | 2004-05-13 | Sepracor, Inc. | Compositions comprising zopiclone derivatives and methods of making and using the same |
| RU2330069C2 (ru) | 2002-11-29 | 2008-07-27 | Мершан Корпорейшн | Способ получения макролидного соединения и штаммы streptomyces sp., mortierella sp. и micromonosporaceae |
| EP1705247A4 (fr) | 2003-11-27 | 2008-08-20 | Mercian Corp | Adn intervenant dans l'hydroxylation d'un compose macrolide |
| CA2552553C (fr) | 2003-11-28 | 2015-01-06 | Kanagawa Academy Of Science And Technology | Methode de detection, diagnostic et remede contre le cancer du foie |
| EP1764592A4 (fr) | 2004-07-02 | 2009-08-19 | Plus One Techno & Co Ltd | Appareil de pesage combiné |
| CN1977046A (zh) | 2004-07-20 | 2007-06-06 | 卫材R&D管理有限公司 | 编码参与普拉地内酯生物合成的多肽的dna |
| TW200716744A (en) | 2005-05-26 | 2007-05-01 | Eisai R&D Man Co Ltd | Genetically modified microorganism and process for production of macrolide compound using the microorganism |
| EP1935893A4 (fr) | 2005-10-13 | 2009-07-22 | Eisai R&D Man Co Ltd | Synthèse totale de pladienolide b et de pladienolide d |
| EP2136209A4 (fr) * | 2007-03-05 | 2010-10-27 | Eisai R&D Man Co Ltd | Procédé pour l'examen d'une action d'un agent anti-cancéreux utilisant un défaut d'épissage en tant que mesure |
| US20080312317A1 (en) | 2007-04-12 | 2008-12-18 | Eisai R&D Management Co., Ltd. | 12 membered-ring macrolactam derivatives |
| JO3668B1 (ar) * | 2014-05-15 | 2020-08-27 | Eisai R&D Man Co Ltd | مركبات بلاديينوليد البيريدين وطرق استعمالها |
-
2016
- 2016-11-17 IL IL259198A patent/IL259198B2/en unknown
- 2016-11-17 CN CN201680067749.5A patent/CN108473479B/zh active Active
- 2016-11-17 KR KR1020187016598A patent/KR20180083376A/ko active Pending
- 2016-11-17 MD MDE20180923T patent/MD3377485T2/ro unknown
- 2016-11-17 US US15/529,798 patent/US10745387B2/en active Active
- 2016-11-17 BR BR112018009995-3A patent/BR112018009995B1/pt active IP Right Grant
- 2016-11-17 SG SG10201913045PA patent/SG10201913045PA/en unknown
- 2016-11-17 AU AU2016357433A patent/AU2016357433B2/en active Active
- 2016-11-17 MX MX2018006155A patent/MX379655B/es unknown
- 2016-11-17 SG SG11201803519YA patent/SG11201803519YA/en unknown
- 2016-11-17 RU RU2018121610A patent/RU2743349C2/ru active
- 2016-11-17 JP JP2017528992A patent/JP6312282B2/ja active Active
- 2016-11-17 ES ES16805664T patent/ES2757174T3/es active Active
- 2016-11-17 CA CA3004623A patent/CA3004623C/fr active Active
- 2016-11-17 WO PCT/US2016/062525 patent/WO2017087667A1/fr not_active Ceased
- 2016-11-17 RU RU2021102393A patent/RU2021102393A/ru unknown
- 2016-11-17 EP EP16805664.6A patent/EP3377485B1/fr active Active
- 2016-11-17 MX MX2021001441A patent/MX392475B/es unknown
-
2018
- 2018-03-16 JP JP2018049098A patent/JP6353620B1/ja active Active
-
2020
- 2020-07-17 US US16/932,627 patent/US20200361915A1/en not_active Abandoned
-
2021
- 2021-02-15 AU AU2021200974A patent/AU2021200974B2/en active Active
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