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SE9901237D0 - Novel use - Google Patents

Novel use

Info

Publication number
SE9901237D0
SE9901237D0 SE9901237A SE9901237A SE9901237D0 SE 9901237 D0 SE9901237 D0 SE 9901237D0 SE 9901237 A SE9901237 A SE 9901237A SE 9901237 A SE9901237 A SE 9901237A SE 9901237 D0 SE9901237 D0 SE 9901237D0
Authority
SE
Sweden
Prior art keywords
hydrogen
fluorophenyl
phenyl
novel use
coch2nh2
Prior art date
Application number
SE9901237A
Other languages
Swedish (sv)
Inventor
Hans Basun
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9901237A priority Critical patent/SE9901237D0/en
Publication of SE9901237D0 publication Critical patent/SE9901237D0/en
Priority to AU39941/00A priority patent/AU3994100A/en
Priority to PCT/SE2000/000643 priority patent/WO2000059496A1/en
Priority to ARP000101558A priority patent/AR023389A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to the use of low affinity NMDA antagonist for the treatment of headache. Preferred compounds include compounds of formula (I): wherein R<1> is pyridyl, phenyl or 4-fluorophenyl; R<2> is phenyl or 4-fluorophenyl; R<3> is hydrogen, C1-6 alkyl or methoxycarbonyl; R<4> is hydrogen or methyl; and R<5> is hydrogen or COCH2NH2.
SE9901237A 1999-04-06 1999-04-06 Novel use SE9901237D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9901237A SE9901237D0 (en) 1999-04-06 1999-04-06 Novel use
AU39941/00A AU3994100A (en) 1999-04-06 2000-04-04 Use of low affinity nmda antagonists for the treatment of headache
PCT/SE2000/000643 WO2000059496A1 (en) 1999-04-06 2000-04-04 Use of low affinity nmda antagonists for the treatment of headache
ARP000101558A AR023389A1 (en) 1999-04-06 2000-04-05 NEW USE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9901237A SE9901237D0 (en) 1999-04-06 1999-04-06 Novel use

Publications (1)

Publication Number Publication Date
SE9901237D0 true SE9901237D0 (en) 1999-04-06

Family

ID=20415133

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9901237A SE9901237D0 (en) 1999-04-06 1999-04-06 Novel use

Country Status (4)

Country Link
AR (1) AR023389A1 (en)
AU (1) AU3994100A (en)
SE (1) SE9901237D0 (en)
WO (1) WO2000059496A1 (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2083972T3 (en) * 1988-08-12 1996-05-01 Astra Ab ARYLALKYL-AMINES AND -AMIDES WITH ANTICONVULSIVE AND NEUROPROTECTORAL PROPERTIES.
DK0501378T3 (en) * 1991-02-28 1995-03-20 Merrell Dow Pharma NMDA antagonists
UA29437C2 (en) * 1992-04-03 2000-11-15 Астра АБ (S)-a-phenyl -2-pyridinetamine or salt thereof with inorganic acid having anticonvulsant activity, a PROCESS for PREPARATION thereof, medicament on their basis and a method for treatment of convulsions
CA2115792C (en) * 1993-03-05 2005-11-01 David J. Mayer Method for the treatment of pain
WO1995006468A1 (en) * 1993-09-01 1995-03-09 Smithkline Beecham Corporation Method for treating migraine headaches
IS4233A (en) * 1993-12-22 1995-06-23 Astra Aktiebolag Misguided ring-related compounds
DE19510189A1 (en) * 1995-03-21 1996-09-26 Hartmut Dr Goebel Use of amantadine
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
CA2270531C (en) * 1996-11-05 2011-08-30 Head Explorer Aps A method for treating tension-type headache

Also Published As

Publication number Publication date
AR023389A1 (en) 2002-09-04
AU3994100A (en) 2000-10-23
WO2000059496A1 (en) 2000-10-12

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