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SE8700250D0 - 8alfa-acylaminoergolines, their production and pharmaceutical compositions containing them - Google Patents

8alfa-acylaminoergolines, their production and pharmaceutical compositions containing them

Info

Publication number
SE8700250D0
SE8700250D0 SE8700250A SE8700250A SE8700250D0 SE 8700250 D0 SE8700250 D0 SE 8700250D0 SE 8700250 A SE8700250 A SE 8700250A SE 8700250 A SE8700250 A SE 8700250A SE 8700250 D0 SE8700250 D0 SE 8700250D0
Authority
SE
Sweden
Prior art keywords
alkyl
phenyl
8alfa
acylaminoergolines
production
Prior art date
Application number
SE8700250A
Other languages
English (en)
Other versions
SE8700250L (sv
Inventor
R Ziegler
P Neumann
W Haefliger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8700250D0 publication Critical patent/SE8700250D0/sv
Publication of SE8700250L publication Critical patent/SE8700250L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE8700250A 1986-01-24 1987-01-22 8alfa-acylaminoergoliner, deras framstellning och farmaceutiska kompositioner innehallande dem SE8700250L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3602058 1986-01-24

Publications (2)

Publication Number Publication Date
SE8700250D0 true SE8700250D0 (sv) 1987-01-22
SE8700250L SE8700250L (sv) 1987-07-25

Family

ID=6292510

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8700250A SE8700250L (sv) 1986-01-24 1987-01-22 8alfa-acylaminoergoliner, deras framstellning och farmaceutiska kompositioner innehallande dem

Country Status (18)

Country Link
JP (1) JPS62190184A (sv)
KR (1) KR870007175A (sv)
AU (1) AU6791487A (sv)
BE (1) BE1000039A4 (sv)
DK (1) DK35787A (sv)
ES (1) ES2003774A6 (sv)
FI (1) FI870293A7 (sv)
FR (1) FR2595699A1 (sv)
GB (1) GB2185743A (sv)
GR (1) GR870093B (sv)
HU (1) HUT45248A (sv)
IL (1) IL81355A0 (sv)
IT (1) IT1216783B (sv)
LU (1) LU86743A1 (sv)
NL (1) NL8700046A (sv)
PT (1) PT84184A (sv)
SE (1) SE8700250L (sv)
ZA (1) ZA87520B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
EP0160842B1 (de) * 1984-04-09 1994-06-22 Schering Aktiengesellschaft 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
RU2013158449A (ru) * 2011-06-23 2015-07-27 Мэп Фармасьютикалс, Инк. Новые фторэрголиновые аналоги
EP2793580A4 (en) * 2011-12-19 2015-05-20 Map Pharmaceuticals Inc NEW DERIVATIVES OF ISO-ERGOLINE
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
CN107405346A (zh) * 2015-01-20 2017-11-28 Xoc制药股份有限公司 异麦角灵化合物及其用途
CA3064274A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds

Also Published As

Publication number Publication date
DK35787A (da) 1987-07-25
IT1216783B (it) 1990-03-14
ES2003774A6 (es) 1988-11-16
IL81355A0 (en) 1987-08-31
DK35787D0 (da) 1987-01-22
FI870293A7 (fi) 1987-07-25
IT8747551A0 (it) 1987-01-22
ZA87520B (en) 1988-09-28
PT84184A (pt) 1987-02-01
KR870007175A (ko) 1987-08-17
GB2185743A (en) 1987-07-29
LU86743A1 (fr) 1987-09-03
AU6791487A (en) 1987-07-30
JPS62190184A (ja) 1987-08-20
GR870093B (en) 1987-05-25
HUT45248A (en) 1988-06-28
BE1000039A4 (fr) 1987-12-15
SE8700250L (sv) 1987-07-25
GB8701274D0 (en) 1987-02-25
FI870293A0 (fi) 1987-01-23
NL8700046A (nl) 1987-08-17
FR2595699A1 (fr) 1987-09-18

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Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8700250-7

Effective date: 19900623