SE8403929L - Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidas - Google Patents
Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidasInfo
- Publication number
- SE8403929L SE8403929L SE8403929A SE8403929A SE8403929L SE 8403929 L SE8403929 L SE 8403929L SE 8403929 A SE8403929 A SE 8403929A SE 8403929 A SE8403929 A SE 8403929A SE 8403929 L SE8403929 L SE 8403929L
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- penicillin
- recombinant dna
- dna molecule
- amidas
- Prior art date
Links
- 102000053602 DNA Human genes 0.000 title abstract 3
- 108020004511 Recombinant DNA Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 244000005700 microbiome Species 0.000 title abstract 2
- 229930182555 Penicillin Natural products 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title 1
- 229940049954 penicillin Drugs 0.000 title 1
- 101001133631 Lysinibacillus sphaericus Penicillin acylase Proteins 0.000 abstract 2
- 108700023418 Amidases Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 102000005922 amidase Human genes 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/84—Penicillin amidase (3.5.1.11)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8403929A SE8403929L (sv) | 1984-07-31 | 1984-07-31 | Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidas |
| EP19850903887 EP0190252A1 (fr) | 1984-07-31 | 1985-07-19 | Molecule d'adn recombinant, microorganismes transformes et procede de production de penicilline v amidase |
| PCT/SE1985/000287 WO1986000929A1 (fr) | 1984-07-31 | 1985-07-19 | Molecule d'adn recombinant, microorganismes transformes et procede de production de penicilline v amidase |
| JP60503412A JPS61502799A (ja) | 1984-07-31 | 1985-07-19 | 組換えdna分子、形質転換された微生物、並びにペニシリンvアミダ−ゼの製造方法 |
| DK141586A DK141586D0 (da) | 1984-07-31 | 1986-03-26 | Rekombinant dna-molekyle, fremgangsmaade til fremstilling deraf, mikroorganismer transformeret dermed og fremgangsmaade til fremstilling af penicillin-v-amidase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8403929A SE8403929L (sv) | 1984-07-31 | 1984-07-31 | Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8403929D0 SE8403929D0 (sv) | 1984-07-31 |
| SE8403929L true SE8403929L (sv) | 1986-02-21 |
Family
ID=20356635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8403929A SE8403929L (sv) | 1984-07-31 | 1984-07-31 | Rekombinant-dna-molekyl, transformerade mikroorganismer och forfarande for framstellning av penicillin v-amidas |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0190252A1 (fr) |
| JP (1) | JPS61502799A (fr) |
| DK (1) | DK141586D0 (fr) |
| SE (1) | SE8403929L (fr) |
| WO (1) | WO1986000929A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9400650D0 (en) * | 1994-01-14 | 1994-03-09 | Smithkline Beecham Biolog | Expression of surface lazer proteins |
| US5516679A (en) * | 1994-12-23 | 1996-05-14 | Bristol-Myers Squibb Company | Penicillin V amidohydrolase gene from Fusarium oxysporum |
| KR100570244B1 (ko) | 1996-11-05 | 2006-04-12 | 브리스톨-마이어스스퀴브컴파니 | 돌연변이 페니실린 g 아실라제 |
| WO2015151118A1 (fr) | 2014-04-04 | 2015-10-08 | Council Of Scientific & Industrial Research | Pénicilline v acylase recombinante et son procédé de préparation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2048894A (en) * | 1979-05-11 | 1980-12-17 | Gist Brocades Nv | Plasmid |
| AU545912B2 (en) * | 1980-03-10 | 1985-08-08 | Cetus Corporation | Cloned heterologous jive products in bacillies |
| NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| DE3330003A1 (de) * | 1982-10-21 | 1984-10-31 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | Dna-sequenz und dna-strukturen und sie verwendendes verfahren zur herstellung von penicillin-acylase |
-
1984
- 1984-07-31 SE SE8403929A patent/SE8403929L/ not_active Application Discontinuation
-
1985
- 1985-07-19 WO PCT/SE1985/000287 patent/WO1986000929A1/fr not_active Ceased
- 1985-07-19 EP EP19850903887 patent/EP0190252A1/fr active Pending
- 1985-07-19 JP JP60503412A patent/JPS61502799A/ja active Pending
-
1986
- 1986-03-26 DK DK141586A patent/DK141586D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61502799A (ja) | 1986-12-04 |
| EP0190252A1 (fr) | 1986-08-13 |
| SE8403929D0 (sv) | 1984-07-31 |
| DK141586A (da) | 1986-03-26 |
| WO1986000929A1 (fr) | 1986-02-13 |
| DK141586D0 (da) | 1986-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8403929-6 Effective date: 19880301 |