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SE8403929L - RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION - Google Patents

RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION

Info

Publication number
SE8403929L
SE8403929L SE8403929A SE8403929A SE8403929L SE 8403929 L SE8403929 L SE 8403929L SE 8403929 A SE8403929 A SE 8403929A SE 8403929 A SE8403929 A SE 8403929A SE 8403929 L SE8403929 L SE 8403929L
Authority
SE
Sweden
Prior art keywords
preparation
penicillin
recombinant dna
dna molecule
amidas
Prior art date
Application number
SE8403929A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8403929D0 (en
Inventor
Sten Gatenbeck
Bjorn Nilsson
Anders Olsson
Mathias Uhlen
Original Assignee
Sten Gatenbeck
Bjorn Nilsson
Anders Olsson
Mathias Uhlen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sten Gatenbeck, Bjorn Nilsson, Anders Olsson, Mathias Uhlen filed Critical Sten Gatenbeck
Priority to SE8403929A priority Critical patent/SE8403929L/en
Publication of SE8403929D0 publication Critical patent/SE8403929D0/en
Priority to EP19850903887 priority patent/EP0190252A1/en
Priority to PCT/SE1985/000287 priority patent/WO1986000929A1/en
Priority to JP60503412A priority patent/JPS61502799A/en
Publication of SE8403929L publication Critical patent/SE8403929L/en
Priority to DK141586A priority patent/DK141586D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A recombinant DNA molecule comprising at least one DNA sequence coding for penicillin V amidase or a derivative thereof, and to a process for its preparation. The invention also relates to microorganisms transformed by said recombinant DNA molecule and to a porocess for their preparation. The invention further relates to a process for preparing penicillin V amidase and to the amidase produced thereby.
SE8403929A 1984-07-31 1984-07-31 RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION SE8403929L (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE8403929A SE8403929L (en) 1984-07-31 1984-07-31 RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION
EP19850903887 EP0190252A1 (en) 1984-07-31 1985-07-19 Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase
PCT/SE1985/000287 WO1986000929A1 (en) 1984-07-31 1985-07-19 Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase
JP60503412A JPS61502799A (en) 1984-07-31 1985-07-19 Recombinant DNA molecules, transformed microorganisms, and methods for producing penicillin V amidase
DK141586A DK141586D0 (en) 1984-07-31 1986-03-26 RECOMBINANT DNA MOLECULE, PROCEDURES FOR PREPARING THEREOF, MICROORGANISMS TRANSFORMED THEREOF AND PROCEDURE FOR PENICILLIN-V-AMIDASE PREPARATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8403929A SE8403929L (en) 1984-07-31 1984-07-31 RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION

Publications (2)

Publication Number Publication Date
SE8403929D0 SE8403929D0 (en) 1984-07-31
SE8403929L true SE8403929L (en) 1986-02-21

Family

ID=20356635

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8403929A SE8403929L (en) 1984-07-31 1984-07-31 RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION

Country Status (5)

Country Link
EP (1) EP0190252A1 (en)
JP (1) JPS61502799A (en)
DK (1) DK141586D0 (en)
SE (1) SE8403929L (en)
WO (1) WO1986000929A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9400650D0 (en) * 1994-01-14 1994-03-09 Smithkline Beecham Biolog Expression of surface lazer proteins
US5516679A (en) * 1994-12-23 1996-05-14 Bristol-Myers Squibb Company Penicillin V amidohydrolase gene from Fusarium oxysporum
KR100570244B1 (en) 1996-11-05 2006-04-12 브리스톨-마이어스스퀴브컴파니 Mutant Penicillin G Acylase
WO2015151118A1 (en) 2014-04-04 2015-10-08 Council Of Scientific & Industrial Research A recombinant penicillin v acylase and process for the prepartion thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2048894A (en) * 1979-05-11 1980-12-17 Gist Brocades Nv Plasmid
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
DE3330003A1 (en) * 1982-10-21 1984-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig DNA SEQUENCE AND STRUCTURES AND METHOD FOR THE PRODUCTION OF PENICILLIN ACYLASE THEREOF

Also Published As

Publication number Publication date
JPS61502799A (en) 1986-12-04
EP0190252A1 (en) 1986-08-13
SE8403929D0 (en) 1984-07-31
DK141586A (en) 1986-03-26
WO1986000929A1 (en) 1986-02-13
DK141586D0 (en) 1986-03-26

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Effective date: 19880301