SE8304818D0 - A MEDICINE HAVING ANTI-ULCER, SPASMOLYTIC AND LOCALLY ANESTHETIC EFFECT - Google Patents
A MEDICINE HAVING ANTI-ULCER, SPASMOLYTIC AND LOCALLY ANESTHETIC EFFECTInfo
- Publication number
- SE8304818D0 SE8304818D0 SE8304818A SE8304818A SE8304818D0 SE 8304818 D0 SE8304818 D0 SE 8304818D0 SE 8304818 A SE8304818 A SE 8304818A SE 8304818 A SE8304818 A SE 8304818A SE 8304818 D0 SE8304818 D0 SE 8304818D0
- Authority
- SE
- Sweden
- Prior art keywords
- spasmolytic
- ulcer
- medicine
- active ingredient
- anesthetic effect
- Prior art date
Links
- 230000003444 anaesthetic effect Effects 0.000 title abstract 2
- 230000000767 anti-ulcer Effects 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 2
- 230000002048 spasmolytic effect Effects 0.000 title abstract 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229940069428 antacid Drugs 0.000 abstract 2
- 239000003159 antacid agent Substances 0.000 abstract 2
- 230000001458 anti-acid effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- HVYGHQWGUABUST-NHCUHLMSSA-N [(1r,2r)-2-pyrrolidin-1-ylcyclohexyl] n-(3-pentoxyphenyl)carbamate Chemical compound CCCCCOC1=CC=CC(NC(=O)O[C@H]2[C@@H](CCCC2)N2CCCC2)=C1 HVYGHQWGUABUST-NHCUHLMSSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to pharmaceutical compositions with antiulcer, spasmolytic and local anaesthetic action, which are particularly suitable for oral administration and contain as active ingredient trans-2-(1-pyrrolidinyl)cyclohexyl 3-n-pentyloxycarbanilate or one of its salts with a pharmaceutically suitable inorganic or organic acid and, preferably, the corresponding hydrochloride, together with a physiologically acceptable vehicle and/or an antacid component. The compositions according to the invention prevent at a daily dose of 10 to 200 mg the formation of tumours, inhibit their spread and shorten the duration of healing, the dosage being less than with conventional compositions having the same action. Combination of the active ingredient with antacid substances is particularly advantageous.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833333008 DE3333008A1 (en) | 1983-09-13 | 1983-09-13 | Pharmaceutical compositions with antiulcer, spasmolytic and local anaesthetic action |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8304818D0 true SE8304818D0 (en) | 1983-09-08 |
| SE8304818L SE8304818L (en) | 1985-03-09 |
| SE462420B SE462420B (en) | 1990-06-25 |
Family
ID=6208945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8304818A SE462420B (en) | 1983-09-13 | 1983-09-08 | APPLICATION OF TRANS-2- (1-PYRROLIDINYL) -CYCLOHEXYL ESTER OF 3-N-PENTYLOXICARBANIC ACID FOR PREPARATION OF A MEDICINAL PRODUCT WITH AN ANGENTIC EFFECT |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS6067421A (en) |
| BE (1) | BE897823A (en) |
| CH (1) | CH654743A5 (en) |
| DE (1) | DE3333008A1 (en) |
| NL (1) | NL8303098A (en) |
| SE (1) | SE462420B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6103380A (en) | 1998-06-03 | 2000-08-15 | Cabot Corporation | Particle having an attached halide group and methods of making the same |
-
1983
- 1983-08-31 CH CH4782/83A patent/CH654743A5/en not_active IP Right Cessation
- 1983-09-07 NL NL8303098A patent/NL8303098A/en not_active Application Discontinuation
- 1983-09-08 SE SE8304818A patent/SE462420B/en not_active IP Right Cessation
- 1983-09-13 DE DE19833333008 patent/DE3333008A1/en active Granted
- 1983-09-19 JP JP58171407A patent/JPS6067421A/en active Granted
- 1983-09-26 BE BE0/211577A patent/BE897823A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE8304818L (en) | 1985-03-09 |
| NL8303098A (en) | 1985-04-01 |
| DE3333008C2 (en) | 1990-06-21 |
| DE3333008A1 (en) | 1985-03-21 |
| JPH045003B2 (en) | 1992-01-30 |
| BE897823A (en) | 1984-01-16 |
| CH654743A5 (en) | 1986-03-14 |
| SE462420B (en) | 1990-06-25 |
| JPS6067421A (en) | 1985-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
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| NUG | Patent has lapsed |
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