[go: up one dir, main page]

SE7906899L - Sulfinylazetidinonforeningar - Google Patents

Sulfinylazetidinonforeningar

Info

Publication number
SE7906899L
SE7906899L SE7906899A SE7906899A SE7906899L SE 7906899 L SE7906899 L SE 7906899L SE 7906899 A SE7906899 A SE 7906899A SE 7906899 A SE7906899 A SE 7906899A SE 7906899 L SE7906899 L SE 7906899L
Authority
SE
Sweden
Prior art keywords
formula
group
alkyl
given above
meanings given
Prior art date
Application number
SE7906899A
Other languages
English (en)
Other versions
SE444810B (sv
Inventor
S P Kukolja
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7906899L publication Critical patent/SE7906899L/sv
Publication of SE444810B publication Critical patent/SE444810B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Claims (5)

Patentkrav 1. Sulfinylazetidinonforeningar avsedda f6r 3-metylencefamsulfoxider cch cefemantibiotika, made av formeln:0 r/SX 0)—Nyt, COCR vdri R betecknar en karboxylsyragruppen akyddande grupp; Hi betecknar (1) en imidogrupp med formeln: R2 •.„ van i 112 betecknar C2-C4-a1 nylen, 22-C4-alkylen, , 2-feny1 ,2-cyklcheen; eller (4) en imidazolidinylgrupp med formeln: 0 /I 3 i vilken R" bar ovan angivna betydelser och Y betecknar acetyl eller nitroso; och X betecknar
1. en grupp med formeln -0R4, dar R4 betecknar vAte, C1-0-alkyl, aryl(C1-03-alkyl) oiler Ci-C6- -halogenalkyl; 2. en grupp med formeln -SR, (Jar R betecknar 01,06-alkyl, aryl eller aryi-(01-03-alkyl); eller 3. en grupp med formeln: 6 -N R7 ,NH3 CH (2) en amidogrupp med formeln: 0 4NH- vari 23 betecknar (o) vRte, C1-C3-alkyl, halogenmetyl eller 3-(2-klorfeny1)-5-metyl-isoxasoly1;
2. bensyloxi, 4-nitrobensyloxi, 2,2,2-trikloretoxi, t-butoxi eller 4-metoxibensyloxi;
3. gruppen R" dKr R" betecknar 1,4-cyklohexadienyl, fenyl, eller fenyl substituerad med 1 eller 2 substituenter valda oberoende am varandra bland: halogen, skyddad hydroxi, nitro, cyano, trifluormetyl, 01-04-alkoxi, C1-04-, fOretrEdesvis C1-C3-alkyl;
4. en grupp med formeln: R" - (0)-022- marl R" bar oven angivna betydelser och m Kr 0 eller 1;
5. en substituerad arylalkylgrupp med formeln: dar (a) R6 betecknar mate och 27 betecknar site, R" med oven angivna betydelser, eller en grupp med formeln -NHR8, dAr R8 betecknar aminokaroonyl, C1-03-alkylaminokarbonYl, C1-03-alkylkarbonyl, C1-03-alkoxikarbonyl eller tosyl; eller (b) 26, 27 och den kvaveatom, mid silken de in bundna, tillsammans betecknar en imidogrupp med formeln: 0 dRr R2 bar oven angivna betydelser. w dgr R'" betecknar R" med ovan angivna betydelser och W betecknar skyddad hydroxi eller skyddad amino; (3) en imidogrupp med formeln: 0 R2 'C N- R"-(0) CH CZ/ m OR/. R" och m har oven angivna betydelser och R2' betecknar C1-C3-alkyl, C2-C3-halogenalkyl, C1-C3-alkoxi eller trikloretoxi; eller Ri betecknar
SE7906899A 1974-12-24 1979-08-17 Sulfinyazetidinonforeningar till anvendning for framstellning av 3-metylencefamsulfoxider SE444810B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53628074A 1974-12-24 1974-12-24
US63273375A 1975-11-19 1975-11-19

Publications (2)

Publication Number Publication Date
SE7906899L true SE7906899L (sv) 1979-08-17
SE444810B SE444810B (sv) 1986-05-12

Family

ID=27065082

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7514550A SE431547B (sv) 1974-12-24 1975-12-22 Forfarande for framstellning av 3-metylencefamsulfoxider
SE7906899A SE444810B (sv) 1974-12-24 1979-08-17 Sulfinyazetidinonforeningar till anvendning for framstellning av 3-metylencefamsulfoxider

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7514550A SE431547B (sv) 1974-12-24 1975-12-22 Forfarande for framstellning av 3-metylencefamsulfoxider

Country Status (25)

Country Link
JP (1) JPS606960B2 (sv)
AR (1) AR220505A1 (sv)
AT (1) AT341672B (sv)
AU (1) AU503202B2 (sv)
BE (1) BE837041A (sv)
BG (2) BG27236A3 (sv)
CA (1) CA1056372A (sv)
CH (3) CH625528A5 (sv)
CS (1) CS191291B2 (sv)
DD (2) DD130933A5 (sv)
DE (1) DE2556045A1 (sv)
DK (1) DK157137C (sv)
ES (2) ES443829A1 (sv)
FR (2) FR2333804A1 (sv)
GB (1) GB1536288A (sv)
GR (1) GR59922B (sv)
HU (2) HU177431B (sv)
IE (1) IE42190B1 (sv)
IL (1) IL48565A (sv)
NL (1) NL182880C (sv)
PL (2) PL113883B1 (sv)
RO (2) RO68478A (sv)
SE (2) SE431547B (sv)
SU (1) SU799667A3 (sv)
YU (2) YU324875A (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190724A (en) * 1978-11-13 1980-02-26 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxides
US4289695A (en) * 1978-11-13 1981-09-15 Eli Lilly And Company Process for preparing 2-chlorosulfinylazetidinones
GB2099817B (en) * 1981-04-10 1985-05-15 Otsuka Kagaku Yakuhin Azetidinone derivatives and process for the preparation of the same
US4436596A (en) * 1982-11-16 1984-03-13 Eli Lilly And Company N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process
DE4230053A1 (de) * 1992-09-08 1994-03-10 Pliva Handels Gmbh 4-Oxo-azetidin-2-sulfonsäureamide und ihre Salze, Verfahren zu deren Herstellung und ihre Verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843682A (en) * 1972-05-15 1974-10-22 Lilly Co Eli 2-chlorosulfinyl-3-imido-azetedin-4-ones

Also Published As

Publication number Publication date
CA1056372A (en) 1979-06-12
NL182880C (nl) 1988-06-01
IL48565A (en) 1979-09-30
JPS5188992A (en) 1976-08-04
YU324875A (en) 1982-02-28
GB1536288A (en) 1978-12-20
AT341672B (de) 1978-02-27
SU799667A3 (ru) 1981-01-23
CS191291B2 (en) 1979-06-29
BG31072A4 (en) 1981-10-15
CH626604A5 (en) 1981-11-30
NL7515069A (nl) 1976-06-28
DK157137C (da) 1990-04-16
IL48565A0 (en) 1976-01-30
PL114521B1 (en) 1981-02-28
BG27236A3 (en) 1979-09-14
FR2300080A1 (fr) 1976-09-03
HU175226B (hu) 1980-06-28
RO74273A (ro) 1981-08-17
AU503202B2 (en) 1979-08-30
CH628620A5 (en) 1982-03-15
DD130933A5 (de) 1978-05-17
AR220505A1 (es) 1980-11-14
FR2333804B1 (sv) 1979-05-18
YU206481A (en) 1983-06-30
RO68478A (ro) 1981-08-30
DK585875A (da) 1976-06-25
IE42190L (en) 1976-06-24
ES457884A1 (es) 1978-08-16
SE444810B (sv) 1986-05-12
NL182880B (nl) 1988-01-04
BE837041A (fr) 1976-06-23
FR2300080B1 (sv) 1979-06-15
DD124985A5 (sv) 1977-03-23
ES443829A1 (es) 1978-03-01
DE2556045A1 (de) 1976-07-08
DE2556045C2 (sv) 1990-08-09
ATA980475A (de) 1977-06-15
JPS606960B2 (ja) 1985-02-21
SE7514550L (sv) 1976-06-25
GR59922B (en) 1978-03-20
AU8708475A (en) 1977-06-02
FR2333804A1 (fr) 1977-07-01
PL113883B1 (en) 1981-01-31
HU177431B (en) 1981-10-28
SE431547B (sv) 1984-02-13
CH625528A5 (en) 1981-09-30
IE42190B1 (en) 1980-06-18
DK157137B (da) 1989-11-13

Similar Documents

Publication Publication Date Title
ES2803516T3 (es) Una forma cristalina de linezolid
DK156717C (da) Analogifremgangsmaade til fremstilling af indomethacinderivater
ES2641178T3 (es) Nuevos polímeros de tetracianoantraquinodimetano y su uso
HUT41770A (en) Process for producing indol derivatives containing heterocyclic substituents and pharmaceutical compositions containing them
CY1111528T1 (el) 1-αζα-δικυκλο [3.3.1] εννεανια
GB1148908A (en) Indole derivatives and processes for making them
SE7906899L (sv) Sulfinylazetidinonforeningar
AU7314098A (en) New chromene compounds, a process for their preparation and pharmaceutical compositions containing them
AU1233188A (en) Deuterated aryl aldehydes and derivatives thereof
JPS5851951B2 (ja) ペニシリンスルホキサイドカラノ スルフイニルハライドノセイホウ
CH612431A5 (en) Process for the preparation of novel indole derivatives
ES430116A1 (es) Un procedimiento mejorado para la preparacion de cefalexinay sales no toxicas y farmaceuticamente aceptables de la mis-ma.
CA2497187A1 (en) Process for preparing nitrooxyderivatives of naproxen
Hjelmgaard et al. Expedient total synthesis of pyrrothine natural products and analogs
GB1469530A (en) 1,3-dioxolane-2-carboxamide derivatives and their use as herbicidal agents
ATE154351T1 (de) 2,3-diphenyl-5-pyrrolyl-furan derivate, verfahren und zwischenprodukte für ihre herstellung und ihre verwendung als entzündungshemmende, antiallergische und blutplättchenaggregationshemmende mittel
KR960007566A (ko) 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도
HUP0101465A2 (hu) Eljárás mátrix fém-proteináz enzimek gátlására hatásos, gátolt szulfonamidok alkilezésére
CA2013743A1 (en) Preparation of glutaric acid derivatives
GB1363758A (en) Process for the production of 1,2,4-oxa-diazoles and novel 1,2,4- oxadiazoles
ES440398A1 (es) Procedimiento para la preparacion de triazapentadienos.
ES409979A1 (es) Un procedimiento para la preparacion de compuestos de 3-oxi-iminometilcefalosporina.
ES2383861B1 (es) Procedimiento de síntesis de intermedios de crambescidinas, de cimipronidina y de sus derivados.
RU2024119253A (ru) Синтетические промежуточные продукты и усовершенствованные процессы получения ингибиторов rock
SU512701A3 (ru) Способ получени пирролидинил-карбоксанилидов

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7906899-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7906899-5

Format of ref document f/p: F