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SE7713586L - Forfarande for framstellning av oxazolidindionderivat av vinkaalkaloider - Google Patents

Forfarande for framstellning av oxazolidindionderivat av vinkaalkaloider

Info

Publication number
SE7713586L
SE7713586L SE7713586A SE7713586A SE7713586L SE 7713586 L SE7713586 L SE 7713586L SE 7713586 A SE7713586 A SE 7713586A SE 7713586 A SE7713586 A SE 7713586A SE 7713586 L SE7713586 L SE 7713586L
Authority
SE
Sweden
Prior art keywords
alcoids
vincal
oxazolidin
procedure
preparation
Prior art date
Application number
SE7713586A
Other languages
English (en)
Other versions
SE436036B (sv
Inventor
J C Miller
G E Gutowski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7713586L publication Critical patent/SE7713586L/sv
Publication of SE436036B publication Critical patent/SE436036B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SE7713586A 1976-12-06 1977-11-30 Analogiforfarande for framstellning av oxazolidindionderivat av vinkaalkaloider SE436036B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (2)

Publication Number Publication Date
SE7713586L true SE7713586L (sv) 1978-06-07
SE436036B SE436036B (sv) 1984-11-05

Family

ID=25005690

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7713586A SE436036B (sv) 1976-12-06 1977-11-30 Analogiforfarande for framstellning av oxazolidindionderivat av vinkaalkaloider
SE7713587A SE435930B (sv) 1976-12-06 1977-11-30 Forfarande for framstellning av ett spirooxazolidindionderivat av vinkaleukoblastin

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7713587A SE435930B (sv) 1976-12-06 1977-11-30 Forfarande for framstellning av ett spirooxazolidindionderivat av vinkaleukoblastin

Country Status (31)

Country Link
US (1) US4096148A (sv)
JP (1) JPS5371100A (sv)
AR (1) AR218467A1 (sv)
AT (2) AT353987B (sv)
AU (1) AU513936B2 (sv)
BE (1) BE861417A (sv)
BG (2) BG33436A3 (sv)
CA (2) CA1082180A (sv)
CH (2) CH632516A5 (sv)
CS (2) CS195344B2 (sv)
DD (2) DD134228A5 (sv)
DE (1) DE2753791A1 (sv)
DK (2) DK144916C (sv)
ES (2) ES464764A1 (sv)
FR (1) FR2372839A1 (sv)
GB (1) GB1590649A (sv)
GR (2) GR67243B (sv)
HK (1) HK57281A (sv)
HU (2) HU180725B (sv)
IE (1) IE46105B1 (sv)
IL (1) IL53506A (sv)
MX (1) MX4326E (sv)
MY (1) MY8200176A (sv)
NL (1) NL7713336A (sv)
NZ (1) NZ185818A (sv)
PL (2) PL110671B1 (sv)
PT (2) PT67343B (sv)
RO (2) RO74137A (sv)
SE (2) SE436036B (sv)
SU (2) SU865127A3 (sv)
ZA (1) ZA777237B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
EP0124502B1 (fr) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT649883A (sv) * 1960-05-24
HU165986B (sv) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
DK144916C (da) 1982-12-06
US4096148A (en) 1978-06-20
ES464764A1 (es) 1979-01-01
BE861417A (fr) 1978-06-02
DE2753791C2 (sv) 1990-08-02
SE7713587L (sv) 1978-06-07
ZA777237B (en) 1979-07-25
PT67342A (en) 1977-12-01
JPS5371100A (en) 1978-06-24
NL7713336A (nl) 1978-06-08
NZ185818A (en) 1979-12-11
DD134228A5 (de) 1979-02-14
FR2372839A1 (fr) 1978-06-30
IE46105L (en) 1978-06-06
ES464765A1 (es) 1979-01-01
CA1082180A (en) 1980-07-22
SE436036B (sv) 1984-11-05
PL106522B1 (pl) 1979-12-31
CA1103664A (en) 1981-06-23
DK541077A (da) 1978-06-07
AR218467A1 (es) 1980-06-13
CH634076A5 (de) 1983-01-14
DK145001C (da) 1982-12-27
DE2753791A1 (de) 1978-06-08
HU180724B (en) 1983-04-29
PT67343A (en) 1977-12-01
MY8200176A (en) 1982-12-31
IE46105B1 (en) 1983-02-23
CS195344B2 (en) 1980-01-31
HK57281A (en) 1981-11-27
GR67243B (sv) 1981-06-25
HU180725B (en) 1983-04-29
JPS625160B2 (sv) 1987-02-03
PT67342B (en) 1979-04-26
DK144916B (da) 1982-07-05
BG33437A3 (bg) 1983-02-15
ATA868877A (de) 1979-05-15
PL110671B1 (en) 1980-07-31
RO75391A (ro) 1980-11-30
CH632516A5 (de) 1982-10-15
AU3123077A (en) 1979-06-14
AT361638B (de) 1981-03-25
FR2372839B1 (sv) 1981-11-06
SU865127A3 (ru) 1981-09-15
ATA868777A (de) 1980-08-15
PL202659A1 (pl) 1978-12-04
AU513936B2 (en) 1981-01-15
GB1590649A (en) 1981-06-03
AT353987B (de) 1979-12-10
RO74137A (ro) 1981-08-30
PL202660A1 (pl) 1978-08-28
BG33436A3 (en) 1983-02-15
IL53506A (en) 1981-09-13
MX4326E (es) 1982-03-24
DD134227A5 (de) 1979-02-14
IL53506A0 (en) 1978-03-10
CS195343B2 (en) 1980-01-31
DK145001B (da) 1982-07-26
DK541177A (da) 1978-06-07
GR67244B (sv) 1981-06-25
PT67343B (en) 1979-04-26
SU843753A3 (ru) 1981-06-30
SE435930B (sv) 1984-10-29

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