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RU93053632A - STEROID ETHERS, METHOD FOR PRODUCING THEM, PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING INFLAMMATORY AND ALLERGIC DISEASES - Google Patents

STEROID ETHERS, METHOD FOR PRODUCING THEM, PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING INFLAMMATORY AND ALLERGIC DISEASES

Info

Publication number
RU93053632A
RU93053632A RU93053632/04A RU93053632A RU93053632A RU 93053632 A RU93053632 A RU 93053632A RU 93053632/04 A RU93053632/04 A RU 93053632/04A RU 93053632 A RU93053632 A RU 93053632A RU 93053632 A RU93053632 A RU 93053632A
Authority
RU
Russia
Prior art keywords
hydrogen
producing
allergic diseases
pharmaceutical composition
compounds
Prior art date
Application number
RU93053632/04A
Other languages
Russian (ru)
Other versions
RU2112775C1 (en
Inventor
Аксельссон Бенгт
Браттсанд Ральф
Кельстрем Лейф
Тален Арне
Original Assignee
Актиеболагет Астра
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9100342A external-priority patent/SE9100342D0/en
Application filed by Актиеболагет Астра filed Critical Актиеболагет Астра
Publication of RU93053632A publication Critical patent/RU93053632A/en
Application granted granted Critical
Publication of RU2112775C1 publication Critical patent/RU2112775C1/en

Links

Claims (1)

Предложены соединения с общей формулой I; в этой формуле 1,2-положение является насыщенным или представляет собой двойную связь, R1 является водородом или же прямой или разветвленной углеводородной цепью, R2 является водородом или же прямой или разветвленной углеводородной цепью, R3 является ацилом, X1 является водородом или галогеном, X2 является водородом или галогеном при условии, что 1) R1 и R2 одновременно не являются водородом, 2) Х1 и Х2 одновременно не являются водородом, 3) если 1,2-положение представляет собой двойную связь R1 и R2 одновременно не являются метильными группами, 4) если 1,2-положение представляет собой двойную связь, R1 является атомом водорода и R2 является прямой или разветвленной углеводородной цепью, имеющей 1-10 атомов углерода, R3 является ацилом, имеющим 11-20 атомов углерода; способы получения этих соединений, фармацевтические препараты, содержащие эти соединения и использование этих соединений для лечения воспалительных и аллергических заболеваний.Compounds with the general formula I are proposed; in this formula, the 1,2-position is saturated or is a double bond, R 1 is hydrogen or a straight or branched hydrocarbon chain, R 2 is hydrogen or a straight or branched hydrocarbon chain, R 3 is acyl, X 1 is hydrogen or halogen, X 2 is hydrogen or halogen, provided that 1) R 1 and R 2 are not hydrogen at the same time, 2) X 1 and X 2 are not hydrogen at the same time, 3) if the 1,2-position is a double bond R 1 and R 2 are not simultaneously methyl groups, 4) e , 1,2-position represents a double bond, R 1 is a hydrogen atom and R 2 is a straight or branched hydrocarbon chain having 1-10 carbon atoms, R 3 is acyl having 11-20 carbon atoms; methods for producing these compounds, pharmaceutical preparations containing these compounds and the use of these compounds for the treatment of inflammatory and allergic diseases.
RU93053632A 1991-02-04 1992-01-29 Steroid esters or their stereoisomers, method of their synthesis, pharmaceutical composition RU2112775C1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9100342-06 1991-02-04
SE9100342A SE9100342D0 (en) 1991-02-04 1991-02-04 NOVEL STEROID ESTERS
SE9100342-6 1991-02-04
PCT/SE1992/000056 WO1992013873A1 (en) 1991-02-04 1992-01-29 Novel steroid esters

Publications (2)

Publication Number Publication Date
RU93053632A true RU93053632A (en) 1997-01-20
RU2112775C1 RU2112775C1 (en) 1998-06-10

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93053632A RU2112775C1 (en) 1991-02-04 1992-01-29 Steroid esters or their stereoisomers, method of their synthesis, pharmaceutical composition

Country Status (37)

Country Link
US (1) US5614514A (en)
EP (1) EP0572451B1 (en)
JP (1) JP2947933B2 (en)
KR (1) KR100205835B1 (en)
CN (3) CN1039329C (en)
AP (1) AP365A (en)
AT (1) ATE164589T1 (en)
BG (1) BG61816B1 (en)
CA (1) CA2100453A1 (en)
CZ (1) CZ282057B6 (en)
DE (1) DE69224982T2 (en)
DK (1) DK0572451T3 (en)
DZ (1) DZ1554A1 (en)
EE (1) EE03110B1 (en)
ES (1) ES2114931T3 (en)
FI (1) FI933451L (en)
HU (1) HU221168B1 (en)
IE (1) IE920167A1 (en)
IL (1) IL100542A (en)
IS (1) IS1653B (en)
MA (1) MA22407A1 (en)
MX (1) MX9200374A (en)
MY (1) MY111502A (en)
NO (1) NO304074B1 (en)
NZ (1) NZ241211A (en)
PL (1) PL170383B1 (en)
PT (1) PT100087B (en)
RO (1) RO111272B1 (en)
RU (1) RU2112775C1 (en)
SE (1) SE9100342D0 (en)
SK (1) SK281802B6 (en)
TN (1) TNSN92008A1 (en)
TW (1) TW287166B (en)
UA (1) UA43825C2 (en)
WO (1) WO1992013873A1 (en)
YU (1) YU48893B (en)
ZA (1) ZA92234B (en)

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