RU2837359C1 - Method for laser rejuvenating therapy of face and neck in combination with application of meso-cocktail, hydrogel mask - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to dermatology and cosmetology, and can be used for laser rejuvenating therapy of face and neck. Laser photothermolysis of periorbital region, face and neck is performed. That is followed by application of an antiaging composition containing hyaluronic acid in high concentration and a polyrevitalising solution containing vitamins, minerals, amino acids, nucleic acids. Then occlusion is created on treated skin surface.

EFFECT: method enables reducing oedema, accelerating the phase of the anti-inflammatory response and prolonging the positive result due to the combination and sequence of action of laser photothermolysis and application of a nutritional mask.

1 cl, 3 ex

Description

The invention relates to cosmetology and can be used in complex procedures of rejuvenating (anti-age) therapy of the face and neck area.

From patent No. 2625297 RU a method of personalized photodynamic therapy of extensive cosmetic skin defects, including topical application of a preparation based on 5-aminolevulinic acid to the skin with subsequent PDT irradiation of the skin using laser radiation with a wavelength of 400-800 nm, according to which a preparation based on 5-aminolevulinic acid is first applied to the entire skin of the face and/or head. Fluorescence spectroscopy is performed 1 hour after application of the preparation to the skin, determining the fluorescence intensity (FI), on the basis of which the laser irradiation dose for PDT is selected from the range of 5-45 J/cm ² , and the lower the FI, the lower the irradiation dose. With an FI value in the range of less than 10 c.u. - the laser irradiation dose is 5-20 J/ ^cm2 , with an IF value of more than 10 conventional units - 21-45 J/ ^cm2 . PDT irradiation of the entire skin is carried out using laser radiation with a wavelength of 400-800 nm. The method allows increasing the effectiveness of PDT of extensive cosmetic changes in the skin due to the personalized selection of the therapeutic dose of laser irradiation taking into account the data of quantitative measurement of the level of accumulation of 5-ALA induced protoporphyrin IX by the method of fluorescence spectroscopy.

A method of vaginal rejuvenation is known from patent No. 2735060 RU. An Nd:YAG laser with a wavelength of 1064 nm is used, and the procedure is carried out in several stages. At the first two stages, the irradiation parameters are successively changed in the "cold", "warm", "hot" modes. Step-by-step processing of the vaginal canal is carried out, the first 3.5-4 cm are carried out at the parameters corresponding to the "hot" mode, reducing the parameters every subsequent 3 cm to the "warm" and "cold" modes. At the same time, at the first stage, sequential circular irradiation of every 5 mm of the vagina is carried out using a conical mirror with a gold coating at a scanner speed of 80-200 revolutions, a power of 22-28 W, with a number of cycles of 2-5. At the second stage, sequential irradiation of the anterior, posterior and lateral walls of every 5 mm of the vagina is performed using an angular mirror at a scanner speed of 150-200 revolutions, with a power of 15-25 W, with a number of cycles of 2-3. At the third stage, sequential irradiation of the vulva and paraurethral region is performed using a manipulator with a spot size of 6 mm with a pulse duration of 100 ms, a pause duration of 50 ms and a power of 15-25 W.

From patent No. 2275881 RU, a method for skin rejuvenation and scar correction using a laser. In the method, the initial laser treatment of the facial skin is carried out at a pulse energy of 1000-1200 mJ until single drops of "blood dew" appear. Further laser treatment is carried out at a laser pulse energy of 200-600 mJ until a yellow-brown film appears when eliminating wrinkles or until a brown coagulation film appears when smoothing scars. After finishing the laser treatment of the skin, a mask made of transparent cotton fabric with "Aurobin" is applied to the wound surface of the skin before epithelialization. The mask is removed from the face after 24 hours. The method allows preventing significant damage to the basal membrane of the epidermis at the ablation stage, and achieving stronger compression of collagen fibers at the thermal contraction stage.

A method for restoring the structure of the skin of the face and neck is known from patent No. 2565373 RU, according to which skin peeling and vaporization with ozonated steam are performed. An application photosensitizer is applied to the face and neck. After 30-40 minutes, a session of photodynamic irradiation (PDI) of the skin of the face and neck is performed. A soothing mask is applied for 15-20 minutes. Before the PDI session, hydrocolonotherapy is performed for a week. Tubage is performed a day after the first session of hydrocolonotherapy. 24 hours after the end of hydrocolonotherapy, the first of 8 sessions of laser puncture of biologically active points of the face and neck is performed, continuously affecting each point for 25 s with laser radiation of the red spectrum. The radiation wavelength is 630 nm, the power is 1 mW. Before applying the application photosensitizer, additional activation of the upper layers of the skin of the face and neck is performed, which are exposed to blue spectrum laser irradiation with a wavelength of 417 nm for 10 minutes. The power density is 50 mW/ ^cm2 , the specific irradiation dose is 7.5 J/ ^cm2 . Each 40-minute session of PDO of the skin of the face and neck is performed with red spectrum laser irradiation with a wavelength of 662 nm, a power density of 150 mW/ ^cm2 at a specific irradiation dose of 27-32 J/ ^cm2 . The first PDO session is performed 48 hours after the first session of laser puncture of biologically active points. Each subsequent PDO session is performed at an interval of 2 weeks from the previous PDO session.

A method for aesthetic correction of involutional changes in facial skin is known from patent No. 2603618 RU. A single-stage effect is performed using low-intensity infrared laser radiation and platelet-rich blood plasma. The effect is performed in two stages: at the first stage, 20-40 ml of venous blood is collected from the patient and centrifuged at 4000 rpm for 5 minutes to obtain a plasma fraction enriched with platelets. At the second stage, the plasma is applied to the facial skin and, without a time interval, the effect is performed using low-intensity infrared laser radiation with a wavelength of 0.89 μm. The pulse repetition frequency is from 80 to 1500 Hz - a mode of constantly changing frequency. Pulse power is 4-6 W / imp. Contact-labile technique, 1-3 minutes per field. Total exposure time is up to 10 minutes. The course includes 10 procedures, performed 2 times a week.

From patent No. 2672281 RU, a device for skin care based on laser therapy of skin tissue is known, which comprises a light source for emitting therapeutic light, an optical system for focusing the therapeutic light to a focal position inside the skin tissue and a positioning element having a contact surface with the skin, wherein the positioning element and the optical system are capable of shifting relative to each other to adapt the distance between the contact surface with the skin and the last lens element of the optical system, which faces the skin surface during use, and the positioning element and the optical system are capable of shifting relative to each other to the therapeutic position (Pt) of the optical system and to an additional position (Pf1) of the optical system, which differs from the therapeutic position. During use and in the therapeutic position, the last lens element of the optical system is in contact with the skin surface in the absence of an air gap between the last lens element and the skin surface.

Patent No. 2722281 RU describes a method for skin rejuvenation in patients with a history of non-melanocytic neoplasms, according to which a photosensitizer is applied to cleansed skin, which is kept until it penetrates the epidermis, and exposed to laser radiation in a continuous mode. A gel containing 0.2% Chlorophylin - CI 75810 as an active substance is used as a photosensitizer. Laser radiation exposure is carried out simultaneously, frontally from the emitter of the LATUS-T "MASK" device with a wavelength of 660 nm, a power density of 100 mW / cm ² , and a procedure duration of 20-25 minutes. The course of treatment is from 6 to 8 procedures every 3-7 days.

A method of laser therapy for patients with trophic ulcers is known from patent No. 2604399 RU. Against the background of standard pharmacotherapy, hydrophilic antibacterial ointments and dressings with antiseptic solutions are used in phase I of the wound process. In phases II and III of the wound process, the drug Curiosin is used. Light exposure is carried out in one session on 1-4 affected areas for 2 minutes per area. Pulse mode. The duration of the light pulse is 100-130 ns. The wavelength is 635 nm. A matrix emitter of 8 laser diodes with a surface area of 8 cm ² is used. The effect is remote at a distance of up to 7 cm. Pulse power is 40 W. VLOC is performed with low-intensity laser radiation in continuous mode with a wavelength of 365-405 nm (UVA spectrum) and 520-525 nm (green spectrum) alternately during 12 daily sessions according to the following scheme: Session 1 - 365-405 nm, power 1-2 mW, exposure 2 minutes; Session 2 - 520-525 nm, power 1-2 mW, exposure 5 minutes; Session 3 - 365-405 nm, power 1-2 mW, exposure 2 minutes; Session 4 - 520-525 nm, power 1-2 mW, exposure 5 minutes; Session 5 - 365-405 nm, power 1-2 mW, exposure 2 minutes; Session 6 - 520-525 nm, power 1-2 mW, exposure 5 minutes; Session 7: 365-405 nm, 1-2 mW power, 2-minute exposure; Session 8: 520-525 nm, 1-2 mW power, 5-minute exposure; Session 9: 365-405 nm, 1-2 mW power, 2-minute exposure; Session 10: 520-525 nm, 1-2 mW power, 5-minute exposure; Session 11: 365-405 nm, 1-2 mW power, 2-minute exposure; Session 12: 520-525 nm, 1-2 mW power, 5-minute exposure.

The closest analogue is the method of treatment (correction) of cosmetic and age-related skin defects known from patent No. 2370275 RU with the combined use of fractional photothermolysis technology with biologically active ingredients, regardless of the method of administration, includes fractional photothermolysis in combination with the introduction of the drug "Coffeeberry". "Coffeeberry" is taken 1 capsule 2 times a day three days before fractional photothermolysis and on the day of its implementation. The method ensures a reduction in post-laser edema, shortening of the inflammatory response phases, elimination of pain and discomfort after the procedure.

The aim of the invention is to increase the effectiveness of the procedure, which consists in increasing the duration of the rejuvenating effect.

The goal is achieved by means of collagen-generating fractional photothermolysis conditions, as well as by subsequent application of a nourishing mask. In general, the fractional photothermolysis technique involves point exposure of the skin to focused laser radiation with a certain density of exposure points and a certain density of laser radiation energy for each point. As a result, so-called fractional columns are formed in the skin. In the present invention, a laser with a wavelength of 1390 nm to 1430 nm is used for photothermolysis. The following exposure parameters are set for the treated areas:

Periorbital area (area around the eyes):

The distance between fractional columns is from 1.1 mm to 1.4 mm;

Laser radiation energy density - 8-12 mJ/microbeam;

The course includes at least 4 procedures with a frequency of 14-21 days.

Face:

The distance between fractional columns is from 0.9 mm to 1.2 mm;

Laser radiation energy density - 18-22 mJ/microbeam;

The course includes at least 3 procedures with a frequency of 14-21 days.

Neck:

The distance between fractional columns is from 0.9 mm to 1.2 mm;

Laser radiation energy density - 13-17 mJ/microbeam;

The course includes 3 to 5 procedures with a frequency of 7-14 days, and the microbeam diameter is from 150 to 400 microns.

Next, an application of an anti-aging therapy composition is performed, including hyaluronic acid in high concentration and a polyrevitalizing solution (vitamins, minerals, amino acids, nucleic acids), for example, NCTF 135 HA. As a result, a synergistic effect is achieved from the effects of laser light and anti-aging therapy drugs, which allows increasing the effectiveness of therapy and eliminating drug injections.

Next, occlusion is created on the treated skin surface, for example, using a hydrogel mask. This increases the effectiveness of the application of the anti-aging therapy composition.

As a result of combining these combined procedures (traditionally used separately) into one method, the effectiveness of anti-aging therapy increases, drug injections are eliminated, and the number of sessions is reduced.

Examples of implementation

Example 1

Patient, 51 years old.

Complaints: atrophic (senile) changes in the skin of the face, decreased turgor of the skin, dry skin, fine wrinkles around the eye area, pastosity around the eyes, hyperpigmentation of senile genesis.

Procedure: Cleanse the face/neck with a cleansing gel, rinse and dry with paper towels.

Next, a photothermolysis procedure was performed on the preorbital region of the eyes using a laser with a wavelength of 1420 nm: the distance between the fractional columns was 1.2 mm, the energy density of the laser radiation was 8 mJ/microbeam, and the diameter of the microbeam was 200 μm.

Next, we applied the drug NCTF 135 HA together with occlusion with a hydrogel mask.

The procedure was repeated 4 times after 15 days.

The cosmetic effect was assessed 7 days after the entire course. The overall assessment of the specialist is that the positive effect is 62%.

Example 2

Patient, 57 years old.

Complaints: atrophic (senile) changes in the skin of the face, decreased turgor of the skin, bright hyperpigmentation in the forehead area of senile origin.

Procedure: Cleanse the face/neck with a cleansing gel, rinse and dry with paper towels.

Next, a photothermolysis procedure was performed on the forehead area using a laser with a wavelength of 1420 nm: the distance between the fractional columns was 0.9 mm, the energy density of the laser radiation was 14 mJ/microbeam, and the diameter of the microbeam was 300 µm.

Next, we applied the drug NCTF 135 HA together with occlusion with a hydrogel mask.

The procedure was repeated 3 times after 15 days. The cosmetic effect was assessed 7 days after the entire course. The overall assessment of the specialist is that the positive effect is 68%.

Example 3

Patient, 47 years old.

Complaints: atrophic (senile) changes in the skin of the face, decreased turgor of the skin, deformed line of the lower jaw and chin (jowls).

Procedure: Cleanse the face/neck with a cleansing gel, rinse and dry with paper towels.

Next, a photothermolysis procedure was performed on the forehead area using a laser with a wavelength of 1420 nm: the distance between the fractional columns was 0.9 mm, the energy density of the laser radiation was 17 mJ/microbeam, and the diameter of the microbeam was 400 µm.

Next, we applied the drug NCTF 135 HA together with occlusion with a hydrogel mask.

The procedure was repeated 3 times after 15 days. The cosmetic effect was assessed 7 days after the entire course. The overall assessment of the specialist is that the positive effect is 68%.

Claims (1)

A method of laser rejuvenating therapy of the face and neck, including fractional laser photothermolysis, application of a mesococtail and a hydrogel mask, applications of nutritional and therapeutic preparations, characterized in that photothermolysis is performed by pulsed laser radiation with a wavelength of 1410 nm ± 20 nm, the microbeam diameter is from 150 to 400 μm, depending on the area, laser photothermolysis is performed under the following conditions: periorbital area (area around the eyes): the distance between fractional columns is from 1.1 mm to 1.4 mm, the energy density of laser radiation is 8-12 mJ / microbeam, the course includes at least 4 procedures with a frequency of 14-21 days; face: the distance between fractional columns is from 0.9 mm to 1.2 mm, the laser energy density is 18-22 mJ/microbeam, the course includes at least 3 procedures with a frequency of 14-21 days; neck: the distance between fractional columns is from 0.9 mm to 1.2 mm, the laser energy density is 13-17 mJ/microbeam, the course includes 3 to 5 procedures with a frequency of 7-14 days, then an anti-aging therapy composition is applied, including high concentration hyaluronic acid and a polyrevitalizing solution containing vitamins, minerals, amino acids, nucleic acids, then occlusion is created on the treated skin surface.