RU2746244C1 - Removable color gel used as an indicator composition to assess the correctness of the impact of the instrument on models or dummies of human body organs - Google Patents

Abstract

FIELD: chemistry.

SUBSTANCE: present invention relates to a removable color gel used as an indicator composition for assessing the correctness of the effect of an instrument on models or dummies of human body organs, containing a base of carboxymethylcellulose, diethylene glycol and sodium hydroxide, glycerin, purified water, flavoring, preservatives and dye, while the content components per 100 g of the finished gel is: carboxymethyl cellulose, g - 15.9-17.5; diethylene glycol, ml - 4.5-5.5; sodium hydroxide, g - 10-11; glycerin, ml - 5.8-6.5; distilled water, ml - 50; flavoring, ml - 4-4.5; preservatives, ml - 5.4-6; dye, ml - 3.5-4.

EFFECT: expansion of the field of application, the possibility of an objective assessment of the correctness of the impact of the instrument on models or dummies of human body organs and the possibility of reusable use.

4 cl, 1 tbl, 4 dwg

Description

The invention relates to compositions that are applied to various surfaces, and can be used as an indicator composition for assessing the correctness of the impact of the instrument on models or dummies of human body organs.

Known removable gels based on agarose from various manufacturers, for example, Accuris (https://www.medicalexpo.ru/prod/accuris-instruments/product-128620-947077.html), Canvax (https://www.medicalexpo.ru/prod /canvax/product-128474-946602.html), Bulldog Bio (https://www.medicalexpo.ru/prod/bulldog-bio-inc/product-128360-945257.html), Genetics (https: // www. medicalexpo.ru/prod/nippon-genetics/product-128292-944221.html), ATCGene (https://www.medicalexpo.ru/prod/actgene-inc/product-128125-947093.html), etc.

Removable gels are also prepared on the basis of silicone, manufacturers are etelec (https://www.directindustry.com.ru/prod/etelec-italia-spa/product-119681-1904024.html), Megatraction (https: //www.medicalexpo .ru / prod / mentor / product-85083-569243.html), Advanced Antivibration Components (https://www.directindustry.com.ru/prod/advanced-antivibration-components/product-67639-852877.html), etc. ...

As the disadvantages of analogs, it can be indicated that these gels:

- cannot be reapplied;

- are produced abroad, and due to the rather high cost with a small number of them, it is inappropriate to use them in the process of training specialists.

Also known is a gel for ultrasound studies containing a base, glycerin and purified water (see RF patent No. 2225729, IPC A61K 49/22, A61K 9/06, publication date 03/20/2004).

The disadvantages of this composition are disposability and narrowness of the scope of its application. When applying a colorless gel to the surface, it is impossible to highlight the zones of "interest" and "errors" and evaluate the correctness of the impact of the instrument on models or dummies of human body organs.

However, no direct analogs were found.

The problem to be solved by the present invention is the development of a removable color gel, which can be used as an indicator composition for assessing the correctness of the tool's impact on models or dummies of human body organs.

The technical result, which is achieved when solving the problem, is expressed in the expansion of the scope, the possibility of an objective assessment of the correctness of the impact of the tool on models or dummies of human body organs, and the possibility of reusable use.

The problem is solved by the fact that the removable color gel, used as an indicator composition for assessing the correctness of the instrument's action on models or dummies of human body organs, contains a base of carboxymethylcellulose, diethylene glycol and sodium hydroxide, glycerin, purified water, flavoring, preservatives and dye, when the content of the components per 100 g of the finished gel is:

carboxymethylcellulose, g 15.9-17.5 diethylene glycol, ml 4.5-5.5 sodium hydroxide, g 10-11 glycerin, ml 5.8-6.5 distilled water, ml fifty flavoring, ml 4-4.5 preservatives, ml 5.4-6 dye, ml 3.5-4

In addition, a menthol flavoring agent is used.

In addition, benzoic, lactic and citric acids are used as preservatives at a ratio in vol.% As 22-32: 37-47: 26-36.

In addition, gum arabic, dextrin, gum, bovine bile and 75% medical alcohol are used as a dye at a ratio in vol.% As 10-20: 20-30: 8-18: 25-35: 12-22.

Comparative analysis of the aggregate of essential features of the proposed technical solution and the aggregate of essential features of analogues indicates its compliance with the "novelty" criterion.

In this case, the features of the claims solve the following functional problems.

The signs "the gel contains a base of carboxymethyl cellulose, diethylene glycol and sodium hydroxide" describe the composition of the base in which carboxymethyl cellulose is a structurant, diethylene glycol is a binder for the components at the second stage of preparation and a plasticizer for carboxymethyl cellulose, and sodium hydroxide is a pH regulator of the mixture obtained at the first stage of preparation ...

The trait "gel ... contains glycerin" describes the use of glycerin as a stabilizer that imparts a gel-like consistency to carboxymethyl cellulose.

The sign "gel ... contains purified water" allows to obtain a finished product in the form of a gel.

The sign "gel ... contains a fragrance" and the sign of the first dependent claim of the formula make it possible to determine the presence of the gel and how long ago it was applied to the surface by the intensity of the aroma, and the fragrance also has a soothing effect when the gel is applied or accidentally hit the human skin.

The sign "the gel additionally contains preservatives" and the sign of the second dependent claim of the formula provide a shelf life of 2-3 years when closed.

The sign "gel ... contains a dye" and the sign of the third dependent clause of the formula allow you to highlight the zones of "interest" and "errors" and to evaluate the correctness of the tool's impact on models or dummies of human body organs.

Figure 1 shows a dummy of a human larynx with a removable colored gel applied to its inner surface.

Figure 2 shows the instrument after the correct action on the dummy of the human larynx.

Figure 3 shows the tool after improper exposure to the dummy of the human larynx.

Figure 4 shows the removable color gel after the instrument is applied to the dummy of the human larynx.

The drawings show a dummy 1 of the human larynx, removable color gel 2, tool 3.

The inventive gel is prepared in several stages using standard technology on standard equipment.

At the first stage, carboxymethyl cellulose is poured with a solution consisting of 98% of the total amount of distilled water and glycerin, and heated to 72 ° C until the mixture swells, then mixed thoroughly by adding sodium hydroxide.

At the second stage, gum arabic is crushed to a powdery state and dissolved in a mixture containing 2% of the total amount of distilled water, diethylene glycol and bovine bile, then dextrin and gum are added. The resulting solution is poured into 2/3 of the total amount of 75% medical alcohol and then insisted in a dark place for 2-3 days.

At the third stage, benzoic, lactic and citric acids with 1/3 of the total amount of 75% medical alcohol are stirred at a temperature of 73 ° C until a fused mixture is obtained.

At the end, the results obtained in the previous steps are mixed with each other until a homogeneous mixture is obtained, with the addition of a flavoring agent.

Examples of removable color gel formulations are shown in Table 1.

Table 1

Removable color gel formulations

Component name, unit of measurement Amount per 100 g of removable color gel, ratio in vol.% Example 1 Example 2 Example 3 Distilled water, ml fifty fifty fifty Carboxymethylcellulose, g 15.9 17.5 16.7 Glycerin, ml 6.5 6.15 5.8 Diethylene glycol, ml five 4.5 5.5 Sodium hydroxide, g eleven 10 10.5 Menthol (flavoring), ml four 4.25 4.5 Preservatives (benzoic, lactic and citric acids), ml 5.7
(22:47:31) 5.4
(32:42:26) 6
(27:37:36) Dye (gum arabic, dextrin, gum, bovine bile, 75% medical alcohol), ml 3.75
(10: 30: 13: 35: 12) four
(20: 25: 8: 30: 17) 3.5
(15: 20: 18: 25: 22)

The result is a removable color gel with the following properties:

- high adhesive properties (with a surface energy of 97-108 J / m) - so that the gel does not quickly drain from the surface of the cavities (within 1.5-3 hours);

- neutral pH level (6.8-7.2), so that it does not react with other substances and does not irritate the human skin;

- the possibility of easy removal of the gel, without the use of special substances or tools;

- average viscosity - value according to Brookfield 16.0-20.0 Pa⋅s, so that visible traces from the impact of the tool remain and remain;

- the gel must maintain its viscosity, i.e. do not harden for 1.5-2 hours - this time is generally enough to carry out manipulation or conduct 1 pair during training;

- the gel can be stored for at least 2 years in a closed state;

- until the gel has hardened, it can be reused, for which it is recommended to pre-stir it.

The obtained laboratory results were tested in the laboratory of ecology of microorganisms with the International Scientific and Educational Center for Biological Safety of the School of Biomedicine of the Far Eastern Federal University and the laboratory of virology of the Federal Research Center of Biodiversity of Terrestrial Biota of East Asia FEB RAS.

The assessment of the correctness of the impact of the tool on models or dummies of human body organs is performed as follows.

1. On the surface of the model or dummy of human body organs, a removable color gel is applied (see figure 1).

To increase the objectivity of the assessment of the correctness of the impact of the instrument, the removable color gel can be applied in the form of a target with the highlighting of the zones of "interest" and "errors" in different colors.

2. If necessary, a model or dummy of human body organs is assembled.

3. Exercise the impact with a tool, an example of which is tweezers with a cotton swab or a cotton swab.

4. Provide visual access to surfaces coated with removable color gel.

5. Analyze the effects of the tool.

To do this, inspect the removed color gel (see Fig. 4) and the depth, trajectory and location of the tool impact are estimated from the traces remaining on it.

At the same time, the student can independently, without involving other experts (for example, a teacher), not only assess the correctness of the tool's impact, but also control the process of performing the manipulation.

When using a removable color gel, it visually remains on the instrument (see Figs. 2 and 3), therefore, after performing the manipulation, the specialist can identify the zones and find out the exact location of the action by the instrument.

In the case of using a target, students' assessments can be ranked depending on the distance from its central part.

If the trace remains in the "error" zone (in the drawings it is colored yellow), i.e. outside the zone of "interest" in the form of a target, this indicates an unsatisfactory assessment and violation of the norms of exposure by the instrument.

1. Remove the color gel from the surface of the model or body dummy (for example, by hand) and clean or change the instrument.

Thus, the inventive removable color gel can be used as an indicator composition to assess the correctness of the impact of the tool on models or dummies of human body organs. These properties help to objectify the process of training specialists and better conduct practical training.

Claims (5)

1. Removable color gel used as an indicator composition for assessing the correctness of the instrument's action on models or dummies of human body organs, containing a base of carboxymethyl cellulose, diethylene glycol and sodium hydroxide, glycerin, purified water, flavoring, preservatives and dye, while the content of the components on 100 g of the finished gel is: carboxymethylcellulose, g 15.9-17.5 diethylene glycol, ml 4.5-5.5 sodium hydroxide, g 10-11 glycerin, ml 5.8-6.5 distilled water, ml fifty flavoring, ml 4-4.5 preservatives, ml 5.4-6 dye, ml 3.5-4 2. The removable color gel according to claim 1, characterized in that a menthol fragrance is used. 3. Removable color gel according to claim 1, characterized in that benzoic, lactic and citric acids are used as preservatives at a ratio in vol.% As 22-32: 37-47: 26-36. 4. Removable color gel according to claim 1, characterized in that gum arabic, dextrin, gum, bovine bile and 75% medical alcohol are used as the dye at a ratio in vol.% As 10-20: 20-30: 8- 18: 25-35: 12-22.

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