RU2682406C1 - Method of prevention and treatment of respiratory diseases in piglets - Google Patents
Method of prevention and treatment of respiratory diseases in piglets Download PDFInfo
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- RU2682406C1 RU2682406C1 RU2017142217A RU2017142217A RU2682406C1 RU 2682406 C1 RU2682406 C1 RU 2682406C1 RU 2017142217 A RU2017142217 A RU 2017142217A RU 2017142217 A RU2017142217 A RU 2017142217A RU 2682406 C1 RU2682406 C1 RU 2682406C1
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- piglets
- respiratory diseases
- treatment
- biologically active
- active composition
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- 208000023504 respiratory system disease Diseases 0.000 title claims abstract description 13
- 238000000034 method Methods 0.000 title claims abstract description 7
- 230000002265 prevention Effects 0.000 title claims abstract description 6
- 241001465754 Metazoa Species 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 11
- 241000257303 Hymenoptera Species 0.000 claims abstract description 6
- 239000002699 waste material Substances 0.000 claims abstract description 5
- 239000003814 drug Substances 0.000 abstract description 8
- 241000255896 Galleria mellonella Species 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000001993 wax Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 3
- 241000282887 Suidae Species 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- FUBFWTUFPGFHOJ-UHFFFAOYSA-N 2-nitrofuran Chemical class [O-][N+](=O)C1=CC=CO1 FUBFWTUFPGFHOJ-UHFFFAOYSA-N 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 241000264877 Hippospongia communis Species 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 229930194936 Tylosin Natural products 0.000 description 1
- 239000004182 Tylosin Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical compound O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 description 1
- 229960004059 tylosin Drugs 0.000 description 1
- 235000019375 tylosin Nutrition 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D99/00—Subject matter not provided for in other groups of this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Feed For Specific Animals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Описание изобретенияDescription of the invention
Изобретение относится к области ветеринарии и предназначено для лечения респираторных заболеваний поросят.The invention relates to the field of veterinary medicine and is intended for the treatment of respiratory diseases of piglets.
Известно, что антропогенные факторы способствуют снижению иммунитета животных к различным заболевания, тем самым, приводя к уменьшению продуктивности. Причина всего этого заключается в погрешностях содержания и кормления поросят. Образовавшие фермерские хозяйства стремясь снизить себестоимость полученной товарной продукции кормят животным несбалансированными рационами, что в дальнейшем приводит к нарушению обменных процессов организма. Это в значительной степени влияет на резистентность животного, особенно молодняка.It is known that anthropogenic factors contribute to a decrease in the immunity of animals to various diseases, thereby leading to a decrease in productivity. The reason for all this is the inaccuracy of keeping and feeding piglets. Established farms in an effort to reduce the cost of the resulting commercial products feed animals with unbalanced diets, which subsequently leads to a violation of the metabolic processes of the body. This greatly affects the resistance of the animal, especially young animals.
Известно достаточно много препаратов для лечения респираторных заболеваний поросят. В частности, для этиотропной терапии больных животных рекомендованы антибиотики, сульфаниламиды, нитрофураны [1-3].Quite a few drugs are known for the treatment of respiratory diseases in piglets. In particular, antibiotics, sulfonamides, nitrofurans are recommended for etiotropic therapy of sick animals [1-3].
К недостаткам этих препаратов относится то, что они угнетают функцию иммунной системы, что и дальнейшем является основной причиной в возникновения вторичной инфекции.The disadvantages of these drugs include the fact that they inhibit the function of the immune system, which is still the main cause of the secondary infection.
Задачей заявленного изобретения является расширение арсенала средств и методов для профилактики и лечения респираторных заболеваний поросят.The objective of the claimed invention is to expand the arsenal of tools and methods for the prevention and treatment of respiratory diseases of piglets.
Поставленная цель достигается тем, что способ для профилактики и лечения респираторных заболеваний поросят включает применение биологически активной композиции из продуктов жизнедеятельности восковой моли и подмора пчел при следующих соотношениях компонентов, мас. %:This goal is achieved by the fact that the method for the prevention and treatment of respiratory diseases of piglets includes the use of a biologically active composition of the waste products of wax moth and dead bees in the following ratios of components, wt. %:
Продукты жизнедеятельности восковой моли 80,0Waste products of wax moth 80.0
Подмор пчел 20,0Dead bees 20.0
Биологически активную композицию получают путем смешивания компонентов и дают поросятам индивидуальным или групповым способом с кормом 2 раза в сутки с интервалом 12 часов 10-20 дней из расчета 1,0 г/кг живой массы животного.The biologically active composition is obtained by mixing the components and give the piglets individually or in a group way with food 2 times a day with an interval of 12 hours 10-20 days at the rate of 1.0 g / kg of live weight of the animal.
В качестве подмора пчел берут сухие тела погибших пчел и измельчают их на электроприборе, например на кофемолке.The dead bodies of dead bees are taken as a bee killing and crushed by an electric appliance, such as a coffee grinder.
Продукты жизнедеятельности восковой моли получают на пасеке, где в 2 ящиках размером 0,125 м3 размещают свежие, чистые восковые соты и на них запускают половозрелых самок восковой моли. Ящики закрывают и оставляют на 6 месяцев. После этого продукты жизнедеятельности восковой моли извлекают из ящиков, помещают в стеклянные трехлитровые емкости при температуре -10 - -15°С на 24 часа. Через 24 часа сухие продукты жизнедеятельности восковой моли смешивают с пчелиным подмором.Wax moth livelihood products are obtained in the apiary, where fresh, clean waxy honeycombs are placed in 2 boxes measuring 0.125 m 3 and sexually mature female moth waxes are launched on them. Boxes are closed and left for 6 months. After that, the vital products of wax moth are removed from the boxes, placed in glass three-liter containers at a temperature of -10 - -15 ° C for 24 hours. After 24 hours, the dry waste products of the wax moth are mixed with bee mortality.
Предполагаемое изобретение стимулирует функцию иммунной системы, настраивая организм поросят на активную борьбу с болезнетворными факторами.The alleged invention stimulates the function of the immune system, tuning the body of piglets to actively combat pathogenic factors.
Пример. Эффективность способа для профилактики и лечения респираторных заболеваний поросят оценивали в период 2016 года в условиях крупного свиноводческого комплекса Тюменской области. Все животные (60 голов) были разделены на две группы: опытную и контрольную. У всех животных опытных и контрольных групп был поставлен диагноз связанный с респираторными заболеваниями (бронхиты, трахеиты, риниты) не вирусной этиологии. Полученную биологически активную композицию, согласно изобретению, вводили опытным группам поросят индивидуальным или групповым способом с кормом 2 раза в сутки с интервалом 12 часов от 10 до 20 дней из расчета 1,0 г/кг живой массы животного в период февраль - апрель. Контрольной группе поросят давали докситил орально с питьевой водой из расчета 1 г препарата на 8-10 кг ж.м. в сутки, в течение 5 дней.Example. The effectiveness of the method for the prevention and treatment of respiratory diseases of piglets was evaluated in the period of 2016 in a large pig-breeding complex of the Tyumen region. All animals (60 animals) were divided into two groups: experimental and control. All animals of the experimental and control groups were diagnosed with respiratory diseases (bronchitis, tracheitis, rhinitis) of non-viral etiology. The obtained biologically active composition, according to the invention, was administered to experimental groups of piglets individually or in a group way with food 2 times a day with an interval of 12 hours from 10 to 20 days at the rate of 1.0 g / kg of live weight of the animal in the period February - April. The control group of piglets was given doxitil orally with drinking water at the rate of 1 g of the drug per 8-10 kg m. per day, for 5 days.
Терапевтическая эффективность заявляемого изобретения составила 100%, терапевтическая эффективность у контрольных животных составила 70%. Использование биологически активной композиции позволило снизить заболеваемость респираторными болезнями свиней на 30% по сравнению с контрольными животными.The therapeutic efficacy of the claimed invention was 100%, therapeutic efficacy in control animals was 70%. The use of a biologically active composition allowed to reduce the incidence of respiratory diseases of pigs by 30% compared with control animals.
Источники информации:Information sources:
1. Вечеркин А.С. Применение амоксиклава и развитие резистентных штаммов бактерий / А.С. Вечеркин // Ветеринария. 2004. - №7 - С. 16-17.1. Vecherkin A.S. The use of amoxiclav and the development of resistant bacterial strains / A.S. Vecherkin // Veterinary medicine. 2004. - No. 7 - S. 16-17.
2. Орлянкин Б.Г. Инфекционные респираторные болезни свиней / Б.Г. Орлянкин, Т.И. Алипер, Е.А. Непоклонов // Ветеринария. 2005. - №11 - С. 3-6.2. Orlyankin B.G. Infectious respiratory diseases of pigs / B.G. Orlyankin, T.I. Alipper, E.A. Nepoklonov // Veterinary medicine. 2005. - No. 11 - S. 3-6.
3. Зуев Н.П. Получение и разработка антимикробных композиций на основе тилозинсодержащих препаратов / Н.П. Зуев // Ветеринарная патология. 2008. - №3(26). - С. 97-100.3. Zuev N.P. Obtaining and development of antimicrobial compositions based on tylosin-containing preparations / N.P. Zuev // Veterinary pathology. 2008. - No. 3 (26). - S. 97-100.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2017142217A RU2682406C1 (en) | 2017-12-04 | 2017-12-04 | Method of prevention and treatment of respiratory diseases in piglets |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2017142217A RU2682406C1 (en) | 2017-12-04 | 2017-12-04 | Method of prevention and treatment of respiratory diseases in piglets |
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| Publication Number | Publication Date |
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| RU2682406C1 true RU2682406C1 (en) | 2019-03-19 |
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| RU2017142217A RU2682406C1 (en) | 2017-12-04 | 2017-12-04 | Method of prevention and treatment of respiratory diseases in piglets |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2181283C2 (en) * | 2000-06-26 | 2002-04-20 | Саратовская научно-исследовательская ветеринарная станция | Method for preventing reproductive- respiratory syndrome in swine |
| RU2307652C1 (en) * | 2006-06-08 | 2007-10-10 | Государственное научное учреждение (ГНУ) Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии (ВНИВИПФиТ) | Method for treating respiratory diseases in farm animals youngsters |
| RU2356543C1 (en) * | 2007-12-18 | 2009-05-27 | Наталья Владимировна Куликова | Preparation "gental" for treatment of gastrointestinal, respiratory diseases in calves and piglets of bacterial etiology and method of treating gastrointestinal, respiratory diseases in calves and piglets of bacterial etiology |
| CN106615821A (en) * | 2016-12-30 | 2017-05-10 | 中悦民安（北京）科技发展有限公司 | Piglet premixed feed for preventing and treating pig cough and asthma and preparation method thereof |
-
2017
- 2017-12-04 RU RU2017142217A patent/RU2682406C1/en not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2181283C2 (en) * | 2000-06-26 | 2002-04-20 | Саратовская научно-исследовательская ветеринарная станция | Method for preventing reproductive- respiratory syndrome in swine |
| RU2307652C1 (en) * | 2006-06-08 | 2007-10-10 | Государственное научное учреждение (ГНУ) Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии (ВНИВИПФиТ) | Method for treating respiratory diseases in farm animals youngsters |
| RU2356543C1 (en) * | 2007-12-18 | 2009-05-27 | Наталья Владимировна Куликова | Preparation "gental" for treatment of gastrointestinal, respiratory diseases in calves and piglets of bacterial etiology and method of treating gastrointestinal, respiratory diseases in calves and piglets of bacterial etiology |
| CN106615821A (en) * | 2016-12-30 | 2017-05-10 | 中悦民安（北京）科技发展有限公司 | Piglet premixed feed for preventing and treating pig cough and asthma and preparation method thereof |
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