RU2365369C1 - Agent for massage - Google Patents

Abstract

FIELD: medicine; cosmetology.

SUBSTANCE: agent contains dogrose and pine nut oil. The agent is well absorbed, provides good slipping effect, normalises muscle tonus. The biologically active substances contained in the formulation, strengthen nutritional quality of the agent.

EFFECT: elimination of vitamin insufficiency and neogenesis of cells of a skin, provision of antiinflammatory and immunostimulating action.

2 dwg, 3 tbl

Description

The invention relates to medical cosmetics and relates to means intended for body massage, and can be used for the complex treatment of children with disabilities with Down syndrome.

It is known the use of various pharmaceutical compositions and compositions for massage (Johnson Baby), obtained by processing fractions of oil with the addition of flavorings and vitamins. However, the use of known drugs is not effective enough, since a feature of the pathology is muscle hypotension, which is detected from the first days of a child's life. With prolonged use, synthetic oils cause dry skin, while children with disabilities with Down syndrome are characterized by increased allergic sensitivity due to vegetative-endocrine disorders, which is manifested in dry skin, a predisposition to fullness and dermatitis.

Closest to the offer is natural olive oil. However, despite the fact that it is natural, but has a higher density, which increases friction and leads to trauma to the skin, its use for children suffering from Down syndrome is not effective enough.

A new technical challenge is to expand the range of massage products based on natural products with tonic and nourishing effects. To solve this problem, a new massage agent containing a nutritious fat base contains pine nut oil as a nutritious fat base, and also contains rosehip oil in the following ratio of components, wt.%:

rosehip oil - 4.0;

pine nut oil - the rest

The product is a mass with the consistency of liquid honey golden orange with a pleasant nutty smell. The product is evenly distributed with a thin layer on the surface of the skin, is well absorbed, provides a good sliding effect and warming up, enhances blood circulation, and normalizes muscle tone. The biologically active substances included in the formulation enhance the nourishing effect of the drug, help eliminate vitamin deficiency and regenerate skin cells, provide anti-inflammatory, tonic and immunostimulating effects.

Handmade syringed cedar nut oil is produced by cold pressing from previously released and refined cedar kernels and is a balanced complex of proteins, fats, and carbohydrates by the Ruzayev laboratory (Tomsk, Russia, TU 9141-001-58913946-04).

The value of handmade cheese squeezed oil is the high content of essential fatty acids with vitamin (F) activity, a complex of tocopherols, vitamins A, B, D and a wide range of trace elements necessary for normal functioning of the human body. Handmade cheese pressed pine nut oil differs from other vegetable oils in its high content of polyunsaturated fatty acids, in particular, linoleic Omega 6 acid and polyunsaturated acid of a specific composition that is not typical for common vegetable oils. These acids are useful for impaired fat and cholesterol metabolism, relieve inflammatory processes, and contribute to improving the structure of the skin. They also have a stimulating effect on the body's immune defense system.

Rosehip oil is produced in Altaivitamins CJSC (reg. No. 002894/01 04.17.2003, pr. No. 16). It stimulates the skin regeneration process. It also contains unsaturated fatty acids (linolenic and linoleic), vitamin E and carotenoids (provitamin A) stimulate the activity of skin cells, improves the immune status of the body.

Trisomy 21 (Down Syndrome) is the most common autosomal chromosomal abnormality in humans. A morphological study of the nervous system of dead patients is characterized by a decrease in the size and weight of the brain, underdevelopment of the frontal lobes; decrease in lateral ventricles; furrows and convolutions are poorly differentiated. In some cases, there are abnormalities in the development of the brain and large cerebral vessels. Histological examination reveals a violation of the differentiation of nerve cells and insufficient myelination of nerve fibers of the brain and spinal cord. Almost all endocrine glands, especially the thyroid gland, adrenal cortex and genital glands, are hypoplastic. Internal organs are reduced in size. In the liver - fat vacuolization, fibrosis. The aorta is narrow, the walls are thin, large vessels are smaller. Congenital heart defects are common (BME, M 1977, p. 594). Most newborns at birth already have clinical manifestations indicative of a diagnosis of trisomy-21. These include: growth lower than in the age group, developmental delay, congenital heart defects, intestinal structural abnormalities, central hypotension, brachycephaly, late closure of fontanelles, small face narrowed to the center, loose joints, short and wide hands, feet and fingers , velvet, mobile, spotty in newborns; rough, dry skin in adolescents. (A.G. Rumyantsev, M.V. Timakova, S.M. Chechelnitskaya. Monitoring the development and health of children. M: Medpraktika-m 2004). In the blood serum of patients there is an increase in the concentration of immunoglobulin G and a decrease in immunoglobulin M. Resistance to infectious diseases is reduced.

The need for rehabilitation of children suffering from trisomy-21 (Down Syndrome) is due to differences in the prevalence and severity of damage to the nervous system (degree of mental retardation), musculoskeletal, cardiovascular systems, and the severity of skin disorders. In the process of rehabilitation, various methods of stimulating mental and physical development are used: aloe extract, cerebrolysin, vitreous body, vitamin therapy, endocrine preparations. However, only complex drug and non-drug therapy, including exercise therapy and massage, increases the rehabilitation potential of the child. It is necessary to use a massage that is strictly differentiated by effect and load, while it is necessary to take into account the shape, age, general condition of the patient's body. Very often, children with Down syndrome are given massage without the use of oils and creams due to their high allergic sensitivity.

Medicinal plants and the preparations obtained from them, including those for massage, have the advantages that, when used, the patient receives a whole complex of related compounds and they affect his body much softer than synthetic drugs, are better tolerated, and less likely to cause side effects. allergic reactions and, as a rule, do not have cumulative properties. Introduction to the composition of means for massage preparations from medicinal plants leads to an increase in the therapeutic and prophylactic effect of the cream due to its biologically active substances.

To establish a qualitative and quantitative combination of oil components, the research literature, clinical and paraclinical studies were analyzed.

For the massage, the composition was used, wt%:

rosehip oil - 4.0;

pine nut oil - the rest.

The product is a mass with the consistency of liquid honey golden orange with a pleasant nutty smell. The product is evenly distributed with a thin layer on the surface of the skin, is well absorbed, provides a good sliding effect and warming up, enhances blood circulation, and normalizes muscle tone.

It is prepared as follows. At room temperature, 4 g of rosehip oil is added to a container with 96 g of cedar oil with stirring and shaken vigorously for one minute. The ratio of the components is chosen optimal to achieve the following goals.

The amount of cedar oil (96 g) should be sufficient for the delivery of rosehip components and at the same time to obtain a stable consistency. The amount of rosehip oil less than 4 g is impractical to apply, because the regeneration process is reduced, the therapeutic effect is not stable enough, and when using rosehip oil in an amount of more than 4 g, a heterogeneous mass is obtained and the patient may be allergic.

The criterion for assessing the impact of the proposed composition on the body of a child suffering from trisomy-21 (Down Syndrome) during massage was a comprehensive indicator of disability according to the international nomenclature of disorders, disability (Moscow - 1995), changes in the emotional state of children were evaluated. The main group received a massage course with compositions based on rosehip oils and pine nuts. The comparison group received a massage using olive oil.

Before the start of therapy, disruptions in the categories of life in children of the main group were determined by the following categories: self-care - half of the children had a second degree of restriction, more than 1/3 of the children had a third, and 10% had a first. In the category of movement, the leading one was the first degree of restriction (more than 2/3 of the children), the second degree was recorded in 1/3 of the children, not one child had a third degree of restriction. Changes were recorded in the education category: more than 2/3 of the children had a 2nd degree, and less than 1/3 of the children had a third degree of restriction. Not one child had the first degree of restriction. Game activity was also impaired in all observed children: in 2/3 of the children, a third degree of restriction was recorded, more than 1/3 of the second degree of restriction. The first degree of restriction in children was not recorded. In the categories of orientation and communication, the second degree of restriction was more often recorded (more than 2/3 of children). Roughly equal indicators were set for the first and third degree of restriction (from 10-20%). In the categories of communication and control over their behavior in more than 2/3 of the children, the second degree of restriction was determined, and the 1st and 3rd degree of restriction were recorded equally often, Fig. 1 (a, b, c).

In the comparison group according to the category of movement, the leading one was the first degree of restriction (more than 2/3 of children) and the third degree (1/3 of children). The change was recorded in the education category: more than 2/3 recorded the second degree of restriction, in about 1/3 of the children - the third degree. In the categories of orientation and communication, the second degree of disability (more than 2/3 of children) was more often recorded, and the remaining degree of restriction was approximately the same frequency for those remaining. In the category: control over their behavior in more than 2/3 of children, a second degree of restriction of vital activity was recorded and, with approximately the same frequency, the first and third degree. The most significant dynamics of reducing the third degree of restriction is established for the categories: game activity and self-service (3 and 2 times, respectively). The deterioration of the third degree of disability is established for one category - training (2 times worse). In other categories of disability without dynamics, figure 2 (a, b, c).

Assessment of the psychoemotional state of children with congenital anomalies, malformations is presented in table 1. In the main group, 2/3 of the children did not come into contact before treatment. Less than half of the children made contact in accordance with the age level. More than 1/5 of the children in the assessment were active and 4/5 passive. About 1/3 of the children were active and alert. More than 2/3 of children are inert and lethargic. Less than half of the children worked with pleasure, just over half from subordination. Efficiency was reduced in approximately 1/3 of the children, sufficient was observed in about 2/3 of the children.

In the main group before treatment, the content of leukocytes, lymphocytes, including CD 3; CD 4; CD 19 and others are impaired in 9 children. Decrease in indicators of KFM were noted in 5 children. Excess indicators were recorded in 4 children. In 1 child, the immune status corresponded to the normal variant. The hypoproduction of Ig, A, M before the start of therapy was determined in 6 children, Ig G in 8 patients, table 2. When applying the Pearson compliance criterion, we proved with probability (P <0.01- <0.002) the effectiveness of treating children in the main group and the comparison group ( X ² 8.76-33.28).

In the comparison group, prior to treatment, the content of leukocytes, lymphocytes, including CD 3; CD 4; CD 8; CD 19 and others were impaired in 10 children, table 3. A decrease in KFM was observed in 6 children. Their excess was recorded in 4 children.

Before the start of therapy, the overproduction of Ig, A was determined in 5, M, G in 7 children, Table 2. In the main group, before treatment, a high titer of Ig G was detected for Cl. Pneum in 8 children, for HSV - in 5, for CMV in 4 children, table 2.

Of particular importance in the treatment of children of this group was massage using the proposed tool. Medicinal plants and the preparations obtained from them, including those for massage, have the advantages that, when used, the patient receives a whole complex of related compounds and they affect his body much softer than synthetic drugs, are better tolerated, and less likely to cause side effects. allergic reactions and, as a rule, do not have cumulative properties. The introduction of biological active substances into the cream made it possible to influence the nonspecific resistance of the body.

For the massage, the composition was used, wt%:

rosehip oil - 4.0;

pine nut oil - the rest.

All patients underwent general classical massage. Massage techniques included: superficial and deep stroking, spiral rubbing, sawing, shearing, squeezing, thrashing. Receptions were used in alternation. The duration of the procedure is 15 minutes, a course of 10 procedures.

Therapeutic gymnastics was carried out in the form of individual or small-group exercises of physical therapy 3 times a week for a duration of 25 minutes (warm-up - 5 minutes, the main part - 15 minutes, final - 5 minutes). Active physical exercises were used: general developmental without objects, with objects (basketballs with a rich color gamut), exercises to develop and correct coordination abilities, exercises to correct posture, arches of the foot, and to develop fine motor skills of the fingers. The pace of exercise from slow to fast, the maximum amplitude. Starting position - lying on your back, stomach, sitting, standing.

To assess the ongoing rehabilitation of children with congenital malformations, we used stepwise control. He assumed registration of changes within 6 months and 2 years. This method was used to evaluate complex indicators characterizing persistent dysfunctions of the child's body.

Results of treatment of children with congenital anomalies, malformations Positive dynamics as a result of rehabilitation was observed in all children. Of particular value is the reduction of the most pronounced degree of restriction (third degree). In the main group, the most significant dynamics of reducing the third degree of restriction is established for the categories: gaming and self-service (6 and 4 times, respectively). In other categories of life limitation, there is no reduction in the third degree. An increase in the number of children with the first degree of restriction was not observed in only one category - education. Especially significant is the increase in children with the first degree of restriction for the category: play activity, self-care, orientation (8, 4, 3 times, respectively). Somewhat less for the category of communication, control over their behavior (2 times). A small dynamics is registered in the category of movement, Fig. 1 (a, b, c), which shows data on the state of life and social insufficiency of children with trisomy-21 (Down Syndrome).

In the comparison group, the most significant dynamics of the third degree decrease and restriction was established for the categories: game activity and self-service (3 and 2 times, respectively). The deterioration of the third degree of disability is established for one category - training (2 times worse). In other categories of disability without dynamics. A significant increase in children with the first group of disability was noted in one category: play activity (6 times). For the other categories of disability, pronounced dynamics was not noted in the first degree of restriction, Fig. 2 (a, b, c), which presents data on the state of life and social insufficiency of patients with trisomy-21 (Down Syndrome) (comparison group).

After the treatment, all indicators of the psychoemotional state of the children of the main group improved. The most significant dynamics were noted in such categories as: working capacity, sufficient (3.5 times improvement in the indicator), the child does not come into contact, the child works from subordination, (3 times improvement in indicators), the child is active (2 improvement in indicators, 5 times), the child makes contact in accordance with the age norm and the child works with pleasure (2 times improvement). At 1.75, the number of sluggish children decreased.

In the comparison group, there were no particular significant dynamics in the psycho-emotional state, Table 1. Assessment of the psychoemotional state in children with trisomy - 21 (Down Syndrome) (X ² - compliance indicator, P - error) When applying the Pearson compliance criterion, we proved with a high degree of probability (P <0.01-0.002) the effectiveness of examination of children in the main group and comparison group (X ² 7.81-22.25).

After the course of treatment, a violation of the content of leukocytes, lymphocytes, subpopulations of CD 3; CD 4; CD 8; CD 19 and others were identified in 6 children. The degree of decrease in the content of leukocytes, lymphocytes, including CD 3, decreased; CD 4; CD 8; CD 19 and others in 3 children. Their increase was noted in 3 children. In 4 children, the immunogram corresponded to the normal variant.

After the treatment, the hypoproduction of Ig, A, M was established in 1 child, Ig G in 3 patients, Table 2. Imbalance of immunoregulatory cells and serum immunoglobulins in children with trisomy - 21 (Down Syndrome) X ² - compliance indicator, P - error

Markers of infectious agents are presented in table 3. After treatment, a high titer of Ig G to Cl. pneum was established in - 5, HSV, CMV - in 2 patients, respectively.

In the comparison group: After treatment, a high titer of Ig G to Cl. pneum. was determined in 5, HSV, CMV - in 4 patients, table 3.

To illustrate the effectiveness of therapy, we provide an extract from the medical history: Example 1. Patient D., 16 years old, diagnosis: Down syndrome; severe mental retardation with a mild violation of behavior associated with a chromosomal disorder; atonic dermatitis; astigmatism; hypertrophy of palatine tonsils of 2-3 degrees; kyphoscoliotic posture; chronic opisthorchiasis; ptosis of 1-2 degrees; severe systemic speech underdevelopment.

Examined by specialist doctors: pediatrician, neurologist, infectious disease specialist, physiotherapist, optometrist, otolaryngologist, optometrist, dermatologist, psychiatrist, endocrinologist. Treatment was prescribed taking into account the severity of the main and concomitant diagnosis of paraclinical and instrumental data.

In the initial assessment of the child’s disability, a second degree of category restriction was established: the ability to self-service with the regular help of other people, the ability to move independently was possible with the help of others, the inability to learn and play (the third degree of restriction). The girl was incapable of orientation and communication (third degree of restriction). She did not control her behavior (third degree of restriction).

Complete blood count: Hb 131 g / l, Eritre. 4.1 · 10 ¹² / l, Thrombus 270 g / l, Lake 6 · 10 ⁹ / l, Eos. 9%, Pal. - 2%, Segm. 24%, Lymph. 41% Mon. 4%, ESR - 7 mm / h. Conclusion: Eosinophilia. Blood biochemical analysis: total protein 67 g / l, urea 3.9 mm / l, creatinine 72 μmol / l, total bilirubin 4.0 μmol / l, glucose 2.8 μmol / l, cholesterol 6.8 μmol / l, ALT - 24 units / liter, ACT - 31 units / liter. Conclusion: hypercholesterolemia. General urinalysis: yellow, transparent, relative density 1017, acid reaction, protein, glucose neg .; epithelium neg. in n / a, mucus is moderate, leukocytes are 1-2 in the field of view, salts are moderate oxolates. Conclusion: oxalaturia. Immunogram: White blood cells abs. - 6200, Lymphocytes - 51%, lymphocytes abs. - 3162, CD3 + (T-lymphocytes) 45.75%; CD3 + abs. - 1446.6; CD4 + (T-helpers) - 19.85%; CD4 + abs. - 287.2; CD8 + (T-cypressors) - 23.95%: CD8 + abs. - 3116.5; Index CD4 + / CD8 + - 0.83; CD3 + CD16 + 56 + - 6.67; CD19 + (B lymphocytes) 5.25%; T-NK 1.19; Ig A 75 mg%, Ig G 1450 mg%, Ig M 70 mg%: ELISA: Ig G to Cl. pneum is sharply positive (1:80). Conclusion: lymphocytosis, impaired H / S balance in the direction of immunodeficiency.

Instrumental methods: Ultrasound of the abdominal organs: diffuse change in the liver, pancreas; computed tomography: multiple calcifications of the left hemisphere, possibly of a congenital nature. The adaptation period at the Center was rather complicated. The child was often ill with acute respiratory infections. Conducted basic therapy + additional non-drug treatment - massage using the proposed tool: cedar oil and rosehip oil with a ratio of components according to the claims.

After two courses of treatment, the child was tested according to the criteria for limiting life activity and social insufficiency of children according to the international nomenclature of violations. The following parameters were evaluated: self-service, movement, training, game activity, orientation, communication, control of one’s behavior. The child has the ability to self-care (first degree of restriction). She began to move better (first degree of restriction). The child did not study in a rehabilitation center under a special program (third degree of restriction). Game activity began to improve (first degree of restriction). Disorientation (first degree of restriction) disappeared in the child. The ability to communicate has improved (second degree of restriction).

Complete blood count: Hb 127 g / l, Eritre. 4.9 · 10 ¹² / l, Thrombus 304 g / l, Lake 5 · 10 ⁹ / l, Eos. 4%, Pal.-1%, Segm. 20% ,, Lymph. 48% Mon. 5%, ESR - 9 mm / h. Conclusion: a variant of the age norm. Blood biochemical analysis: Total protein 78 g / l, urea 4.4 mm / l, creatinine 71 μmol / l, total bilirubin 5.0 μmol / l, glucose 3.1 μmol / l, cholesterol 4.9 μmol / l, ALT - 13 U / L, ACT - 17 U / L. Conclusion: a variant of the age norm. General analysis of urine: color yellow, transparent, relative density 1015, acidic reaction, protein, glucose neg .; epithelium 1-2 in s / sp., mucus moderately, leukocytes neg., salts - oxolates moderately. Conclusion: oxalaturia. Immunogram: White blood cells abs. - 7500, Lymphocytes - 45%, abs. - 3375, CD3 + (T-lymphocytes) 60.12%; CD3 + abs. - 2029.05; CD4 + (T-helpers) - 34.4%; CD4 + ABS - 697.9; CD8 + (T-suppressors) - 26.65%; CD8 + abs. - 540.7; Index CD4 + / CD8 + - 1.29; CD3 + CD16 + 56 + - 11.2; CD19 + (B lymphocytes) 17.4%; T-NK - 1.73 Ig A 100 mg%, Ig G - 1530 mg%, Ig M - 50 mg%; ELISA: Ig G to Cl. pneum positive (1:20). Conclusion: lymphocytosis, otherwise without features.

The girl became less ill with colds.

The dynamics of the incidence of acute respiratory infections: 2005 - 4 times, 2006 - 1 time.

Thus, the use of the proposed means for massage contributed to a significant improvement in the health status of sick children with Down Syndrome (figure 1, 2).

Repeated analysis by flow cytofluorimetry confirmed the improvement of blood immunological parameters (normalization of the main cell markers, stabilization of the immunoregulatory index), table 2. The titer of antibodies to antigens to the causative agents of some infectious diseases (Ig G) decreased, tab. 3 Markers of causative agents of some infectious and parasitic diseases in patients with trisomy - 21 (Down Syndrome) X ² - compliance indicator, P - error

When applying the Pearson compliance criterion, we proved with probability (P <0.01- <0.002) the effectiveness of treating children in the main group and the comparison group (X ² - 8.44-15.93).

Thus, the proposed solution allows you to create an effective tool for massage based on highly natural raw materials of the Siberian region.

Table 1 Categories The main group of 10 children Control group 10 children X ² R Before treatment After treatment Before treatment After treatment Contact: a) does not enter 6 2 5 four 8.88 <0.01 b) in accordance with the age norm four 8 5 6 14.49 <0.002 Child: a) active 2 5 3 four 7.81 <0.01 b) passive 8 5 7 6 17.76 <0.002 Child: a) active 3 four 5 6 10.03 <0.01 b) inert 7 6 5 four 13.06 <0.01 Child: a) peppy 3 6 5 6 11.20 <0.01 b) sluggish 7 four 5 four 8.7 <0.01 The child works: a) with pleasure. four 8 6 7 15.44 <0.002 b) from submission 6 2 four 3 7.89 <0.01 Performance a) reduced 8 3 7 6 22.25 <0.002 b) sufficient 2 7 3 four 9.9 <0.01

table 2 Indicators The main group of 10 children Comparison group 10 children X ² R Before treatment After treatment Before treatment After treatment White blood cells 2 0 5 3 9.51 <0.01 Lymphocytes 8 5 6 four 33.28 <0.002 CD 3 (t lymph.) four one 7 5 10.48 <0.01 CD 4 (t helpers) 6 3 5 four 12.83 <0.002 CD 8 (t sup.) 5 four 8 6 13.97 <0.002 CD 4+ / CD 8+ 9 6 10 8 18.57 <0.002 CD 3 + CD 16 + CD 56 7 four 5 3 9.7 <0.01 CD 19 four one 6 four 17.3 <0.002 TNK 7 6 four four 10.9 <0.01 Ig A 6 one 5 3 8.76 <0.01 Ig M 6 one 7 7 14.5 <0.002 Ig G 8 3 6 7 15.6 <0.002

Table 3 Pathogens The main group of 10 children Comparison group 10 children X ² R Before treatment After treatment Before treatment After treatment Cl.trach 0 0 0 0 - - Cl.pneum 8 5 7 5 15.93 <0.002 HSV 5 2 6 four 10.08 <0.01 CMV four 2 5 four 8.44 <0.01 TOXOPLASMS one one one one - - TOXOKARA 0 0 0 0 - - Lamblia one 0 2 2 - - OPISTORCHES one one 2 2 - -

Claims (1)

A massage product containing a nutritious fat base, characterized in that cedar nut oil is used as a nutritive fat base, and also additionally contains rosehip oil in the following ratio, wt.%:
Rosehip oil 4.0 Pine nut oil Rest

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