RU2364432C1 - Therapy of helminthic invasions - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to veterinary science and concerns treatment of helminthic invasions ensured by introduction into gastrointestinal tract of a dog, a cat, or a pig of vegetable-oil agent prepared as follows: in a dark-glass pot containing corn oil 800.0 g (85.2 wt %), under stirring powdered dry plants are added including horse gowan blossom 20.0 g (2.1 wt %), peppermint leaves, blossom and stems 20.0 g (2.1 wt %), common plantain leaves 20.0 g (2.1 wt %), ginger plant inflorescences 15.0 g (1.6 wt %), vitamin pumpkin seed 30.0 g (3.2 wt %), common thyme leaves and stems 20.0 g (2.1 wt %), ground shield-roots rhizome 15.0 g (1.6 wt %). The mixture is drawn under stirring within 20-25 days. Further, oily infusion is separated. Per each 100 g thereof, sea-buckthorn oil 6.0 g (6 wt %) and formalin 0.6 g (0.6 wt %) are added. The agent is given to animals within five-six days before forage and water in dose 0.2-1.0 ml/kg of body weight on end.

EFFECT: method provides integrated anthelmintic and antiinflammatory, wound healing action on gastrointestinal mucosa of animals without by-effects.

Description

The alleged invention relates to veterinary medicine and, specifically to methods for treating diseases caused by round and ribbon helminths in patients with a single-chamber stomach and intestines of small length.

According to the patent of the Russian Federation No. 2311175, 2007, a method for treating wounds is known, in which, after the toilet, a medicine is applied once or repeatedly to the wound, for the preparation of which they take 15.0 g (6.5 wt.%) Of dried flowers, ground to powder pharmacy chamomile and 15.0 g (6.5 wt.%) of dry leaves of large plantain, insist 15 days at room temperature and constantly stirring at the beginning in 100.0 g (43.1 wt.%) of sea buckthorn oil, then in 100.0 g (43.1 wt.%) Of a 5% aqueous solution of analgin mixed with 2.0 g (0.8 wt.%) Formalin.

The purpose of the invention is the creation of an inexpensive, oil-free drug that does not contain toxic chemical anthelmintics, which has a destructive effect on round and ribbon worms, has anti-inflammatory, hemostatic, wound healing and other effects on the surface of mucous membranes injured by worms, due to which the intake of microorganisms and toxins, toxins is significantly reduced toxic substances from the intestines.

This goal is achieved by the fact that for a patient with a single-chamber stomach and with a small intestinal length (people, dogs, cats, pigs) five to six consecutive days before eating and water are given a dose of 0.2-0.1 ml / kg body weight a preparation for the preparation of which in a dark glass container with 800.0 g (85.2 wt.%) corn oil is placed with stirring 20.0 g (2.1 wt.%) powder from chamomile flowers, 20.1 g ( 2.1 wt.%) From dry leaves, flowers and stalks of peppermint, 20.1 g (2.1 wt%) from dry leaves of large plantain, 15.0 g (1.6 wt.%) From dry social thyme of tansy, 30.0 g (3.2 wt.%) from the seeds of vitaminized pumpkin, 20.0 g (2.1 wt.%) from dried leaves and stems of thyme, 15.0 g (1.6 wt. .%) of the maximally chopped rhizome of the male thyroid, then for every 100.0 g of oil infusion add 6.0 g (6.0 wt.%) sea buckthorn oil and 0.6 g (0.6 wt.%) formalin.

Preparation technology: dry herbal medicinal substances are crushed to powders, male thyroid rhizome is crushed as much as possible, placed in a dark glass container with constant stirring in 800.0 g of corn oil, left at room temperature and mixed for infusion. After 20-25 days, the oil infusion is separated, 6.0 g of sea buckthorn oil with 0.6 g (0.6 wt.%) Formalin is added for every 100.0 g of it, the extracts are fed to pigs at therapeutic doses, the preparation is kept in a dark place at a temperature of 2-6 ° C.

Pharmacodynamics of the ingredients of the drug:

- substances of leaves, flowers, and chamomile pharmacy in the infusion have anti-inflammatory, hemostatic, antiseptic, analgesic, sedative, anticonvulsant, choleretic, slightly astringent effects, normalize the functioning of the gastrointestinal tract (2, p. 212; 4, p. 250);

- substances of leaves, flowers and stalks of peppermint have analgesic, wound healing, antispasmodic action, normalize the work of the stomach and intestines (2, p. 171; 4, p. 191);

- substances of the leaves of large plantain have anti-inflammatory, bactericidal, wound healing, laxative effect, regulate the work of the stomach with both high and low acidity of gastric juice (2, p. 192; 4, p. 232);

- substances of flower baskets of tansy ordinary tones the muscles of the gastrointestinal tract, increase the secretion of its glands, increase bile secretion, have a pronounced destructive effect on acaride and pinworms (2, p. 189; 4, p. 224);

- substances of vitaminized pumpkin seeds have a detrimental effect on round and ribbon worms (2, p.239);

- substances of stems and leaves of thyme ordinary have antiseptic, disinfecting and anthelmintic action (4, p. 281);

- the substances of the rhizome of the male thyroid gland have a detrimental effect on the tapeworms, and their rapid death occurs due to muscle paralysis (4, p.339);

- sea buckthorn oil, obtained from the pulp of fruits, has analgesic, epithelizing, granulating properties (4, p.203);

- formalin is an aqueous solution of formaldehyde - a clear liquid with a peculiar smell, has an antimicrobial, disinfecting, and slightly irritating effect (1, p. 500);

- corn oil, for example, "Milora" of the first extraction, deodorized, frozen out, odorless, cholesterol, rich in vitamins - it is a solvent of medicinal substances of plants (4, p. 156), has a choleretic and blood-clotting effect. In single-chamber stomachs, the oil and substances in it do not break down due to the lack of enzymes acting on fats, getting into the intestine unchanged, they act gently, envelop the bodies of round and ribbon worms, disrupting their breathing process, at the same time, medicinal substances of plants exert on they have their own destructive effect, at the same time, the medicinal substances of plants in the aggregate have anti-inflammatory, hemostatic, wound healing and other effects on the mucous membrane of the worm damaged by worms shechnik.

Thus, corn oil and sea buckthorn oil, not split in the stomach, with all medicinal substances of plants in the intestine contained in them, have a destructive effect on round and ribbon helminths, have anti-inflammatory, hemostatic, wound healing and other therapeutic effects on mucous membranes damaged by worms, and activate intestinal motility in which helminths are driven into the external environment. Naturally, before starting treatment, it is necessary to create such conditions under which helminth eggs would not be a source of infection.

Preliminary tests showed that the drug in therapeutic doses and proper treatment does not change the clinical condition of dogs and weaned piglets, is harmless and has good therapeutic efficacy.

We believe that the drug will find wide application not only in veterinary medicine.

Literature

1. Veterinary Encyclopedic Dictionary. M., 1952, volume 2.

2. Kovaleva N.G. Treatment with plants. M., "Medicine", 1971

3. Moiseev O.N. A method of treating wounds. RF patent No. 2311175, 2007

4. Schröter A.I., Muravyova D.A., Pakaln D.A., Efimova F.V. Medicinal flora of the Caucasus. M., "Medicine", 1973. Pages are indicated in the text.

Claims (1)

A method for the treatment of helminthic invasions in veterinary medicine, characterized in that a dog, cat or pig is injected with an oil preparation in the gastrointestinal tract, prepared as follows: in a dark glass container containing 800.0 g (85.2 wt.%) corn oil is placed under stirring with crushed 20.0 g (2.1 wt.%) dried chamomile flowers, 20.0 g (2.1 wt.%) dried leaves, flowers and stalks of peppermint, 20.0 g (2 , 1 wt.%) Of dry leaves of large plantain, 15.0 g (1.6 wt.%) Of dried inflorescences of common tansy, 30.0 g (3.2 wt.%) Of dried seeds of pumpkin v taminated, 20.0 g (2.1 wt.%) dry leaves and stems of thyme, 15.0 g (1.6 wt.%) dry rhizomes of male thyroid, the mixture is infused for 20-25 days with stirring, the oil infusion is separated , for each 100 g it is added 6.0 g (6 wt.%) sea buckthorn oil and 0.6 g (0.6 wt.%) formalin, the mixture is given to the animal at a dose of five to six days in a row before feed and water intake 2-1.0 ml / kg body weight.