RU2236861C1 - Curative-prophylactic preparation for treating skin diseases of different etiology - Google Patents
Curative-prophylactic preparation for treating skin diseases of different etiology Download PDFInfo
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- RU2236861C1 RU2236861C1 RU2003115494/15A RU2003115494A RU2236861C1 RU 2236861 C1 RU2236861 C1 RU 2236861C1 RU 2003115494/15 A RU2003115494/15 A RU 2003115494/15A RU 2003115494 A RU2003115494 A RU 2003115494A RU 2236861 C1 RU2236861 C1 RU 2236861C1
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- RU
- Russia
- Prior art keywords
- skin diseases
- curative
- licorice
- treating skin
- hydrochloric
- Prior art date
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- 208000017520 skin disease Diseases 0.000 title claims description 10
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims abstract description 8
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 8
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims abstract description 8
- 229940010454 licorice Drugs 0.000 claims abstract description 8
- 244000205574 Acorus calamus Species 0.000 claims abstract description 7
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 6
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical class O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 241000202807 Glycyrrhiza Species 0.000 claims description 7
- 235000011996 Calamus deerratus Nutrition 0.000 claims description 6
- 235000019197 fats Nutrition 0.000 claims description 6
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 claims description 6
- 229960000282 metronidazole Drugs 0.000 claims description 6
- 239000002674 ointment Substances 0.000 claims description 6
- 229940098465 tincture Drugs 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 229910017604 nitric acid Inorganic materials 0.000 claims description 4
- 230000000069 prophylactic effect Effects 0.000 claims description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 3
- 244000060011 Cocos nucifera Species 0.000 claims description 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 2
- 235000013367 dietary fats Nutrition 0.000 claims description 2
- 239000010520 ghee Substances 0.000 claims description 2
- 235000021400 peanut butter Nutrition 0.000 claims description 2
- 239000013543 active substance Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 6
- 235000014121 butter Nutrition 0.000 abstract description 3
- 235000006480 Acorus calamus Nutrition 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000019483 Peanut oil Nutrition 0.000 abstract 1
- 239000003240 coconut oil Substances 0.000 abstract 1
- 235000019864 coconut oil Nutrition 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000312 peanut oil Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 201000004384 Alopecia Diseases 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229940124091 Keratolytic Drugs 0.000 description 1
- 241000721454 Pemphigus Species 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 208000006311 Pyoderma Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000842 anti-protozoal effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 229940125715 antihistaminic agent Drugs 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 238000009341 apiculture Methods 0.000 description 1
- 235000021425 apple cider vinegar Nutrition 0.000 description 1
- 229940088447 apple cider vinegar Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 230000001632 homeopathic effect Effects 0.000 description 1
- 230000001694 hyposensitizing effect Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000001530 keratinolytic effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000037306 mature skin Effects 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 238000009160 phytotherapy Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Изобретение относится к области медицине и косметологии и касается создания лекарственных средств для лечения кожных заболеваний различной этиологии.The invention relates to the field of medicine and cosmetology and for the creation of medicines for the treatment of skin diseases of various etiologies.
Лекарственные растения в дерматологии используются в виде определенных лекарственных форм: настоев, отваров, настоек, присыпок, мазей, паст и т.д.Medicinal plants in dermatology are used in the form of certain dosage forms: infusions, decoctions, tinctures, powders, ointments, pastes, etc.
Проблема лечения и профилактики кожных заболеваний была и остается одной из наиболее актуальных в современной дерматологииThe problem of treatment and prevention of skin diseases has been and remains one of the most relevant in modern dermatology
Широко используются медикаментозные (глюкокортикостероидные, антигистаминные, антибиотические, иммуномодулирующие, витаминные и т.д. препараты) методы лечения и профилактики рецидивов заболевания.Widely used are medication (glucocorticosteroid, antihistamines, antibiotic, immunomodulatory, vitamin, etc. drugs) methods of treatment and prevention of relapse of the disease.
Имеется значительная группа натуральных средств (лекарственные фитопрепараты, продукты пчеловодства, гомео- и аромапрепараты), которые с успехом применяются в терапии больных дерматозами (Корсун В.Ф., Фитотерапия кожных заболеваний, Минск, Беларусь, 2001).There is a significant group of natural remedies (medicinal herbal remedies, beekeeping products, homeopathic and aromatic preparations), which are successfully used in the treatment of patients with dermatoses (V. Korsun, Phytotherapy of skin diseases, Minsk, Belarus, 2001).
Задачей настоящего изобретения является разработка нового комплексного состава в виде мази для лечения кожных заболеваний различной этиологии.The objective of the present invention is to develop a new complex composition in the form of ointments for the treatment of skin diseases of various etiologies.
Предложено лечебно-профилактическое средство для лечения кожных заболеваний различной этиологии, включающее 40% спиртовые настойки аира и солодки, 10% салициловую, или соляную, или азотную кислоту, метронидазол и жировую основу при следующем соотношении компонентов, мл на 100 г мази:A therapeutic and prophylactic agent is proposed for the treatment of skin diseases of various etiologies, including 40% alcohol tinctures of calamus and licorice, 10% salicylic, or hydrochloric, or nitric acid, metronidazole and a fat base in the following ratio of components, ml per 100 g of ointment:
40%-ная спиртовая настойка аира 1040% alcohol tincture of calamus 10
40%-ная спиртовая настойка солодки 1040% alcohol tincture of licorice 10
10%-ная салициловая, или соляная,10% salicylic, or hydrochloric,
или азотная кислота 5or nitric acid 5
Метронидазол 0,25 гMetronidazole 0.25 g
Жировая основа ОстальноеFat base
Кроме того, лечебно-профилактическое средство в качестве жировой основы содержит сливочное, кокосовое, топленое, арахисовое масло.In addition, the therapeutic and prophylactic agent as a fat base contains butter, coconut, ghee, peanut butter.
Препараты аира стимулируют функции пищеварительного тракта, печени и желчного пузыря. Аир полезен в комплексном лечении пиодермии, вульгарных угрей, облысения.Calamus preparations stimulate the functions of the digestive tract, liver and gall bladder. Air is useful in the complex treatment of pyoderma, acne vulgaris, baldness.
Препараты солодки оказывают гипосенсибилизирующее, противозудное, противовоспалительное и т.д. действие. В научной медицине солодку используют при аллергических зудящих дерматозах, пузырчатке, псориазе.Licorice preparations have a hyposensitizing, antipruritic, anti-inflammatory, etc. act. In scientific medicine, licorice is used for allergic itchy dermatoses, pemphigus, psoriasis.
Метронидазол проявляет антибактериальное и противопротозойное действие.Metronidazole has an antibacterial and antiprotozoal effect.
Салициловая кислота используется в качестве антисептического, кератолитического и отвлекающего средства.Salicylic acid is used as an antiseptic, keratolytic and distracting agent.
Предложенное средство готовят следующим образом.The proposed tool is prepared as follows.
Метронидазол в количестве 0,25 г измельчают и растворяют в смеси, содержащей 10 мл 40%-ной спиртовой настойки аира и 10 мл 40%-ной спиртовой настойки солодки. Далее смешивают с жировой основой и добавляют 5 мл одной из кислот (в зависимости от показаний). Все тщательно перемешивают. Хранить в холодильнике.Metronidazole in the amount of 0.25 g is crushed and dissolved in a mixture containing 10 ml of 40% alcohol tincture of calamus and 10 ml of 40% alcohol tincture of licorice. Next, mix with the fat base and add 5 ml of one of the acids (depending on the indications). All mix thoroughly. Keep refrigerated.
Полученную мазь равномерно наносить на чистую кожу лица 1 раз в деньThe resulting ointment should be applied evenly to clean skin once a day
Для повышения эффективности лечения целесообразно использовать дополнительно лечебно-косметические процедуры, а именно перед нанесением мази лицо протереть подкисленной водой (яблочным уксусом, лимонным соком и т.д.)To increase the effectiveness of treatment, it is advisable to use additional cosmetic procedures, namely, before applying the ointment, wipe the face with acidified water (apple cider vinegar, lemon juice, etc.)
Предложенное средство было апробировано на добровольцах на территории санатория “Узкое”. Были пролечены больные (возрастная категория от 16 лет до 65). После проведения курса лечения от 1 до 2 месяцев у больных с угревой сыпью и дерматозами происходит формирование здоровой зрелой кожи. При крапивнице и аллергических высыпаниях - воспаление, покраснение и зуд снимается в течение 2-3 дней. Неприятных субъективных ощущений не зафиксировано.The proposed tool was tested on volunteers in the sanatorium "Uzkoye". Patients were treated (age range from 16 years to 65). After a course of treatment from 1 to 2 months in patients with acne and dermatoses, healthy mature skin is formed. With hives and allergic rashes, inflammation, redness and itching are removed within 2-3 days. Unpleasant subjective sensations are not fixed.
Следует отметить, что сбалансированное использование входящих компонентов дает максимально возможный терапевтической эффект.It should be noted that the balanced use of incoming components gives the maximum possible therapeutic effect.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003115494/15A RU2236861C1 (en) | 2003-05-27 | 2003-05-27 | Curative-prophylactic preparation for treating skin diseases of different etiology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003115494/15A RU2236861C1 (en) | 2003-05-27 | 2003-05-27 | Curative-prophylactic preparation for treating skin diseases of different etiology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2236861C1 true RU2236861C1 (en) | 2004-09-27 |
| RU2003115494A RU2003115494A (en) | 2004-11-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2003115494/15A RU2236861C1 (en) | 2003-05-27 | 2003-05-27 | Curative-prophylactic preparation for treating skin diseases of different etiology |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2236861C1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2288734C1 (en) * | 2005-06-24 | 2006-12-10 | Юлия Ивановна Коршикова | Composition for skin care possessing anti-itching effect |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2018314C1 (en) * | 1993-07-15 | 1994-08-30 | Приморское научное медико-техническое общество | Agent for treatment of eczema |
| RU2074730C1 (en) * | 1993-05-24 | 1997-03-10 | Николай Яковлевич Костеша | Ointment for skin diseases treatment: eczema, psoriasis, neurodermatitis |
| RU2134568C1 (en) * | 1995-10-27 | 1999-08-20 | Медисиз Фармасьютикал Корпорейшн | Compositions used for treatment of cutaneous disorders and methods of their using |
| RU2151589C1 (en) * | 1996-07-30 | 2000-06-27 | Л'Ореаль | Anti-inflammatory agent, composition containing this agent, method of treatment of patients with dermatological and systemic inflammatory diseases |
-
2003
- 2003-05-27 RU RU2003115494/15A patent/RU2236861C1/en not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2074730C1 (en) * | 1993-05-24 | 1997-03-10 | Николай Яковлевич Костеша | Ointment for skin diseases treatment: eczema, psoriasis, neurodermatitis |
| RU2018314C1 (en) * | 1993-07-15 | 1994-08-30 | Приморское научное медико-техническое общество | Agent for treatment of eczema |
| RU2134568C1 (en) * | 1995-10-27 | 1999-08-20 | Медисиз Фармасьютикал Корпорейшн | Compositions used for treatment of cutaneous disorders and methods of their using |
| RU2151589C1 (en) * | 1996-07-30 | 2000-06-27 | Л'Ореаль | Anti-inflammatory agent, composition containing this agent, method of treatment of patients with dermatological and systemic inflammatory diseases |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2288734C1 (en) * | 2005-06-24 | 2006-12-10 | Юлия Ивановна Коршикова | Composition for skin care possessing anti-itching effect |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20090528 |