RU2143274C1 - Homeopathic drug "tabakum-plus multigran" for treatment of patients with tobacco dependence - Google Patents
Homeopathic drug "tabakum-plus multigran" for treatment of patients with tobacco dependence Download PDFInfo
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- RU2143274C1 RU2143274C1 RU99108763A RU99108763A RU2143274C1 RU 2143274 C1 RU2143274 C1 RU 2143274C1 RU 99108763 A RU99108763 A RU 99108763A RU 99108763 A RU99108763 A RU 99108763A RU 2143274 C1 RU2143274 C1 RU 2143274C1
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- treatment
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- patients
- tobacco dependence
- dependence
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- 239000003814 drug Substances 0.000 title claims abstract description 9
- 208000025569 Tobacco Use disease Diseases 0.000 title claims abstract description 8
- 230000001632 homeopathic effect Effects 0.000 title claims description 12
- 229940079593 drug Drugs 0.000 title description 4
- 239000008187 granular material Substances 0.000 claims abstract description 10
- 241000968111 Lobelia inflata Species 0.000 claims abstract description 7
- 244000010922 Plantago major Species 0.000 claims abstract description 7
- 235000015266 Plantago major Nutrition 0.000 claims abstract description 7
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims abstract description 6
- 244000061176 Nicotiana tabacum Species 0.000 claims abstract description 6
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims abstract description 6
- 240000008440 Passiflora incarnata Species 0.000 claims abstract description 6
- 235000011922 Passiflora incarnata Nutrition 0.000 claims abstract description 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000011777 magnesium Substances 0.000 claims abstract description 6
- 229910052749 magnesium Inorganic materials 0.000 claims abstract description 6
- 239000011593 sulfur Substances 0.000 claims abstract description 6
- 229910052717 sulfur Inorganic materials 0.000 claims abstract description 6
- 239000012895 dilution Substances 0.000 claims description 2
- 238000010790 dilution Methods 0.000 claims description 2
- 235000001055 magnesium Nutrition 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract description 5
- 235000019504 cigarettes Nutrition 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 230000004060 metabolic process Effects 0.000 abstract description 3
- 206010011224 Cough Diseases 0.000 abstract description 2
- 208000000059 Dyspnea Diseases 0.000 abstract description 2
- 206010013975 Dyspnoeas Diseases 0.000 abstract description 2
- 206010022998 Irritability Diseases 0.000 abstract description 2
- 206010057852 Nicotine dependence Diseases 0.000 abstract description 2
- 230000037396 body weight Effects 0.000 abstract description 2
- 230000000391 smoking effect Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 239000003061 homeopathic agent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 229960002715 nicotine Drugs 0.000 description 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 2
- 241000157855 Cinchona Species 0.000 description 1
- 235000021516 Cinchona officinalis Nutrition 0.000 description 1
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 244000107975 Strychnos nux-vomica Species 0.000 description 1
- 206010043268 Tension Diseases 0.000 description 1
- 235000005811 Viola adunca Nutrition 0.000 description 1
- 240000009038 Viola odorata Species 0.000 description 1
- 235000013487 Viola odorata Nutrition 0.000 description 1
- 235000002254 Viola papilionacea Nutrition 0.000 description 1
- 244000029687 Wikstroemia indica Species 0.000 description 1
- 239000011449 brick Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- UFMZWBIQTDUYBN-UHFFFAOYSA-N cobalt dinitrate Chemical compound [Co+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O UFMZWBIQTDUYBN-UHFFFAOYSA-N 0.000 description 1
- 229910001981 cobalt nitrate Inorganic materials 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- LJCNRYVRMXRIQR-OLXYHTOASA-L potassium sodium L-tartrate Chemical compound [Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O LJCNRYVRMXRIQR-OLXYHTOASA-L 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000005586 smoking cessation Effects 0.000 description 1
- 235000011006 sodium potassium tartrate Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Изобретение относится к медицине, а именно к комбинированным гомеопатическим препаратам, снижающим и купирующим зависимость от никотина, и может применяться для отвыкания от табакокурения. Для лечения данной патологии из литературных и патентных данных известно гомеопатическое лекарственное средство для лечения табачной зависимости "Биолайн Стоп Смоукин", обладающее иммуностимулирующим и адаптогенным действием и содержащее: Daphne indica, Plantago major, Cinchona officinalis. Lobelia inflata, Nux vomica, Staphysagria, Calcarea phosphorica, Ignatia amara (РЛС России, 5 изд., 1997/1998, М. , с. 766). Указанное средство является наиболее близким к заявляемому техническому решению. The invention relates to medicine, namely to combined homeopathic medicines that reduce and stop the dependence on nicotine, and can be used for smoking cessation. For the treatment of this pathology from the literature and patent data, a homeopathic drug for the treatment of tobacco dependence "Bioline Stop Smookin" is known, which has an immunostimulating and adaptogenic effect and containing: Daphne indica, Plantago major, Cinchona officinalis. Lobelia inflata, Nux vomica, Staphysagria, Calcarea phosphorica, Ignatia amara (Radar of Russia, 5th ed., 1997/1998, M., p. 766). The specified tool is the closest to the claimed technical solution.
Однако описанное средство имеет некоторые ограничения в применении: его нельзя использовать в лечении табачной зависимости у подростков (до 12 лет); при беременности и кормлении грудью перед началом лечения необходима консультация врача. However, the described tool has some limitations in use: it can not be used in the treatment of tobacco dependence in adolescents (up to 12 years); during pregnancy and lactation, a doctor's consultation is necessary before starting treatment.
Задачей настоящего изобретения является расширение арсенала отечественных гомеопатических средств, представляющих собой комбинированный препарат, направленный на расширение фармакологического спектра действия. Предлагаемое гомеопатическое средство позволяет снизить и купировать зависимость от никотина, при этом нормализуется обмен веществ, в частности липидный обмен, что позволяет курильщикам плавно уменьшать количество выкуренных сигарет и отвыкать от табакокурения, не сталкиваясь с проблемой ожирения. Поставленная задача достигается тем, что гомеопатическое лекарственное средство для лечения табачной зависимости, помимо Lobelia inflata и Plantago major, дополнительно содержит Nicotiana tabacum, Passiflora incarnata. Magnesium carbonicum, Sulfur, взятые в равных соотношениях, при определенном разведении компонентов: Lobelia inflata - C6; Nicotiana tabacum - C3; Plantago major - C3; Passiflora incarnata - C5; Magnesium carbonicum - C6; Sulfur - C3. The objective of the present invention is to expand the arsenal of domestic homeopathic remedies, which are a combined preparation aimed at expanding the pharmacological spectrum of action. The proposed homeopathic remedy allows you to reduce and stop the dependence on nicotine, while metabolism, in particular lipid metabolism, is normalized, which allows smokers to smoothly reduce the number of smoked cigarettes and wean from smoking, without encountering the problem of obesity. The objective is achieved in that the homeopathic medicine for the treatment of tobacco dependence, in addition to Lobelia inflata and Plantago major, additionally contains Nicotiana tabacum, Passiflora incarnata. Magnesium carbonicum, Sulfur, taken in equal proportions, with a certain dilution of the components: Lobelia inflata - C6; Nicotiana tabacum - C3; Plantago major - C3; Passiflora incarnata - C5; Magnesium carbonicum - C6; Sulfur - C3.
Предложенный состав может быть выполнен в виде сахарных гранул. Все входящие в заявленный состав компоненты известны в гомеопатии и разрешены в медицинской практике (Гомеопатическая Фармакопея Германии, 1985). The proposed composition can be made in the form of sugar granules. All components included in the claimed composition are known in homeopathy and are permitted in medical practice (Homeopathic Pharmacopoeia of Germany, 1985).
Изобретение иллюстрируется следующим примером. The invention is illustrated by the following example.
Пример. Состав: на 100 г гранул:
Lobelia inflata - C6 0.17 г
Nicotiana tabacum - C3 0.17 г
Plantago major - C3 0.17 г
Passiflora incarnata - C3 0.17 г
Magnesium carbonicum - C6 0.17 г
Sulfur - C3 0.17 г
Вспомогательные вещества (сахарная крупка по ГОСТ 7060-79) до 100,0 г. Заявляемое средство получают следующим образом. 100 г ненасыщенных гранул гомеопатических увлажняют 1 г спирта этилового 45% в закрытом сосуде, затем добавляют поровну потенцированные растворы гомеопатических компонентов, входящих в состав комплексного препарата, и динамизируют в течение 10 минут.Example. Composition: per 100 g of granules:
Lobelia inflata - C6 0.17 g
Nicotiana tabacum - C3 0.17 g
Plantago major - C3 0.17 g
Passiflora incarnata - C3 0.17 g
Magnesium carbonicum - C6 0.17 g
Sulfur - C3 0.17 g
Excipients (sugar grains according to GOST 7060-79) up to 100.0 g. The inventive tool is obtained as follows. 100 g of unsaturated homeopathic granules moisturize 1 g of ethyl alcohol 45% in a closed vessel, then evenly potentiated solutions of the homeopathic components that make up the complex preparation are added and dynamized for 10 minutes.
Характеристика конечного продукта
Внешний вид. Однородные гранулы правильной шаровидной формы белого с серым или кремовым оттенком цвета, без запаха.End product characterization
Appearance. Homogeneous granules of regular spherical shape in white with a gray or cream shade, odorless.
Подлинность. Authenticity.
1. 5 гранул помещают в колбу вместительностью 50 мл, прибавляют 1 мл 1% раствора кислоты хлористоводородной и нагревают на кипящей бане до полного растворения гранул в течение 5 минут. Затем прибавляют 2 мл реактива Фелинга и нагревают на кипящей водяной бане в течение 5 минут. Выпадает осадок кирпично-красного цвета (сахара). 1. 5 granules are placed in a 50 ml flask, 1 ml of a 1% hydrochloric acid solution is added and heated in a boiling bath until the granules are completely dissolved within 5 minutes. Then add 2 ml of Feling's reagent and heat in a boiling water bath for 5 minutes. The precipitate is brick red (sugar).
2. 2 гранулы растворяют в 0.5 мл воды, прибавляют 0.1 мл раствора натрия гидроксида, 0.1 мл раствора кобальта нитрата; появляется сине-фиолетовое окрашивание (сахара). 2. 2 granules are dissolved in 0.5 ml of water, 0.1 ml of sodium hydroxide solution, 0.1 ml of cobalt nitrate solution are added; appears blue-violet staining (sugar).
Примечание. Приготовление реактива Фелинга по ГФ 11 изд., вып.2, с. 125. При отсутствии сегнетовой соли реактив Фелинга готовят следующим образом: около 3.5 г перекристаллизованного меди сульфата (ГОСТ 4165-78) растворяют в 50 мл воды, подкисленной 2 каплями кислоты серной разведенной. Note. Preparation of the Feling reagent according to the Global Fund 11th ed., Issue 2, p. 125. In the absence of Rochelle salt, the Feling reagent is prepared as follows: about 3.5 g of recrystallized copper sulfate (GOST 4165-78) is dissolved in 50 ml of water, acidified with 2 drops of diluted sulfuric acid.
Клинические испытания проведены на базе Московского гомеопатического центра. Clinical trials were conducted on the basis of the Moscow Homeopathic Center.
Противопоказания и побочные эффекты не выявлены. No contraindications and side effects have been identified.
Взаимодействие с другими препаратами: не выявлено. Interaction with other drugs: not detected.
Дозировка и способ применения: по 8 гранул 3 раза в день под язык до полного рассасывания за 15 минут до еды. Dosage and method of application: 8 granules 3 times a day under the tongue until complete resorption 15 minutes before meals.
Курс лечения 3 месяца. По рекомендации врача в зависимости от тяжести заболевания курс лечения повторяют через 1 месяц. The course of treatment is 3 months. On the recommendation of a doctor, depending on the severity of the disease, the treatment is repeated after 1 month.
Лечение предложенным средством мягко снимает никотиновую зависимость, постепенно исчезают сопровождающие ее симптомы: раздражительность, нервное напряжение, депрессия, кашель, отдышка. Пациенты чувствуют себя комфортно: при уменьшении количества выкуриваемых сигарет не наблюдается тенденции к увеличению массы тела, т. к. предложенное средство одновременно нормализует обмен веществ. Treatment with the proposed agent gently removes nicotine addiction, the symptoms accompanying it gradually disappear: irritability, nervous tension, depression, cough, shortness of breath. Patients feel comfortable: with a decrease in the number of cigarettes smoked, there is no tendency to increase body weight, because the proposed tool at the same time normalizes metabolism.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU99108763A RU2143274C1 (en) | 1999-05-06 | 1999-05-06 | Homeopathic drug "tabakum-plus multigran" for treatment of patients with tobacco dependence |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU99108763A RU2143274C1 (en) | 1999-05-06 | 1999-05-06 | Homeopathic drug "tabakum-plus multigran" for treatment of patients with tobacco dependence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2143274C1 true RU2143274C1 (en) | 1999-12-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU99108763A RU2143274C1 (en) | 1999-05-06 | 1999-05-06 | Homeopathic drug "tabakum-plus multigran" for treatment of patients with tobacco dependence |
Country Status (1)
| Country | Link |
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| RU (1) | RU2143274C1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2070544A2 (en) | 2007-12-13 | 2009-06-17 | Marianna Gross | Means of withdrawal from smoking |
| DE202014103194U1 (en) | 2014-07-11 | 2014-07-29 | Marianna Gross | Homeopathic remedy for smoking cessation |
| EP3911412A1 (en) * | 2019-01-17 | 2021-11-24 | Edelweiss Laboratory SA | Formulation for treating tobacco or psychotrope withdrawal symptoms |
-
1999
- 1999-05-06 RU RU99108763A patent/RU2143274C1/en not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Реестр лекарственных средств России 1997/1998. - М.: 5 изд., с. 766. * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2070544A2 (en) | 2007-12-13 | 2009-06-17 | Marianna Gross | Means of withdrawal from smoking |
| EP2070544A3 (en) * | 2007-12-13 | 2010-03-24 | Marianna Gross | Means of withdrawal from smoking |
| DE202014103194U1 (en) | 2014-07-11 | 2014-07-29 | Marianna Gross | Homeopathic remedy for smoking cessation |
| WO2016005563A1 (en) | 2014-07-11 | 2016-01-14 | Marianna Gross | Homeopathic agent allowing smokers to quit smoking |
| CN106714815A (en) * | 2014-07-11 | 2017-05-24 | M·格罗斯 | Homeopathic Remedies for Smokers to Quit |
| RU2736490C2 (en) * | 2014-07-11 | 2020-11-17 | Марианна ГРОСС | Homeopathic remedy for smoking cessation |
| EP3911412A1 (en) * | 2019-01-17 | 2021-11-24 | Edelweiss Laboratory SA | Formulation for treating tobacco or psychotrope withdrawal symptoms |
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Effective date: 20180507 |