[go: up one dir, main page]

RU2018117360A3 - - Google Patents

Download PDF

Info

Publication number
RU2018117360A3
RU2018117360A3 RU2018117360A RU2018117360A RU2018117360A3 RU 2018117360 A3 RU2018117360 A3 RU 2018117360A3 RU 2018117360 A RU2018117360 A RU 2018117360A RU 2018117360 A RU2018117360 A RU 2018117360A RU 2018117360 A3 RU2018117360 A3 RU 2018117360A3
Authority
RU
Russia
Application number
RU2018117360A
Other versions
RU2018117360A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2018117360A publication Critical patent/RU2018117360A/ru
Publication of RU2018117360A3 publication Critical patent/RU2018117360A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/51Physical structure in polymeric form, e.g. multimers, concatemers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/52Physical structure branched
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2018117360A 2015-12-04 2016-12-02 Сконструированные нуклеиновые кислоты, нацеленные на нуклеиновую кислоту RU2018117360A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562263232P 2015-12-04 2015-12-04
US62/263,232 2015-12-04
PCT/US2016/064860 WO2017096328A1 (en) 2015-12-04 2016-12-02 Engineered nucleic-acid targeting nucleic acids

Publications (2)

Publication Number Publication Date
RU2018117360A RU2018117360A (ru) 2020-01-09
RU2018117360A3 true RU2018117360A3 (ru) 2020-01-09

Family

ID=57750577

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018117360A RU2018117360A (ru) 2015-12-04 2016-12-02 Сконструированные нуклеиновые кислоты, нацеленные на нуклеиновую кислоту

Country Status (17)

Country Link
US (4) US9771600B2 (ru)
EP (2) EP3564371B1 (ru)
JP (1) JP6707133B2 (ru)
KR (1) KR102093570B1 (ru)
CN (1) CN108473981B (ru)
AU (2) AU2016363024B2 (ru)
CA (1) CA3004757C (ru)
DK (1) DK3371310T3 (ru)
ES (1) ES2735773T3 (ru)
HK (1) HK1252755B (ru)
IL (1) IL259148B (ru)
MX (1) MX391311B (ru)
NZ (2) NZ756843A (ru)
RU (1) RU2018117360A (ru)
SG (1) SG11201803593QA (ru)
WO (1) WO2017096328A1 (ru)
ZA (1) ZA201802968B (ru)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6707133B2 (ja) * 2015-12-04 2020-06-10 カリブー・バイオサイエンシーズ・インコーポレイテッド 操作された核酸標的化核酸
DK3272867T3 (da) * 2016-06-02 2019-12-02 Sigma Aldrich Co Llc Anvendelse af programmerbare dna-bindingsproteiner til forbedring af målrettet genommodifikation
US12286727B2 (en) 2016-12-19 2025-04-29 Editas Medicine, Inc. Assessing nuclease cleavage
EP3615672A1 (en) 2017-04-28 2020-03-04 Editas Medicine, Inc. Methods and systems for analyzing guide rna molecules
CN112501254B (zh) 2017-07-14 2024-07-19 上海吐露港生物科技有限公司 一种Cas蛋白的用途及靶标核酸分子的检测方法和试剂盒
US11584955B2 (en) * 2017-07-14 2023-02-21 Shanghai Tolo Biotechnology Company Limited Application of Cas protein, method for detecting target nucleic acid molecule and kit
EP3652312A1 (en) 2017-07-14 2020-05-20 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
WO2019041296A1 (zh) 2017-09-01 2019-03-07 上海科技大学 一种碱基编辑系统及方法
CN118389609A (zh) * 2017-09-11 2024-07-26 加利福尼亚大学董事会 抗体介导的cas9向哺乳动物细胞的递送
WO2019152941A1 (en) 2018-02-05 2019-08-08 Caribou Biosciences, Inc. Engineered gut microbes for reduction of reactivation of detoxified drugs
CA3087715A1 (en) 2018-02-08 2019-08-15 Zymergen Inc. Genome editing using crispr in corynebacterium
GB2589246A (en) 2018-05-16 2021-05-26 Synthego Corp Methods and systems for guide RNA design and use
AU2019291918B2 (en) 2018-06-29 2025-06-12 Editas Medicine, Inc. Synthetic guide molecules, compositions and methods relating thereto
SG11202101227TA (en) * 2018-08-09 2021-03-30 G Flas Life Sciences Novel crispr-associated protein and use thereof
CN109517722B (zh) * 2018-09-28 2022-04-01 德拜至臻医学科技(杭州)有限公司 一种捕获特定微量细胞的装置及其制作和使用方法
JP2022520139A (ja) 2018-10-12 2022-03-29 セラダプティブ インク β-リン酸三カルシウム結合配列を含むポリペプチドとその使用
WO2020176389A1 (en) 2019-02-25 2020-09-03 Caribou Biosciences, Inc. Plasmids for gene editing
EP4048063A4 (en) 2019-10-23 2023-12-06 Pairwise Plants Services, Inc. Compositions and methods for rna-templated editing in plants
EP4054621A4 (en) * 2019-11-05 2023-12-27 Pairwise Plants Services, Inc. COMPOSITIONS AND METHODS FOR REPLACING RNA-ENCODED DNA ALLELES
WO2021194604A2 (en) * 2020-03-06 2021-09-30 Theradaptive, Inc. Therapeutic compositions comprising graft materials and beta-tcp binding peptides and uses thereof
US11851702B2 (en) * 2020-03-23 2023-12-26 The Broad Institute, Inc. Rapid diagnostics
EP4135750A4 (en) 2020-04-15 2024-08-21 Theradaptive, Inc. COMPOSITIONS AND METHODS FOR TARGETED THERAPEUTIC RELEASE IN BONE
IL308806A (en) 2021-06-01 2024-01-01 Arbor Biotechnologies Inc Gene editing systems including nuclease crisper and their uses
CN114540325B (zh) * 2022-01-17 2022-12-09 广州医科大学 靶向dna去甲基化的方法、融合蛋白及其应用
CN116377104B (zh) * 2022-11-14 2024-01-12 海南省农业科学院蔬菜研究所 一种快菜高温胁迫内参基因及其引物及应用
WO2024173645A1 (en) 2023-02-15 2024-08-22 Arbor Biotechnologies, Inc. Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript
WO2025171210A1 (en) 2024-02-09 2025-08-14 Arbor Biotechnologies, Inc. Compositions and methods for gene editing via homology-mediated end joining

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10087431B2 (en) 2010-03-10 2018-10-02 The Regents Of The University Of California Methods of generating nucleic acid fragments
AU2011253222B2 (en) 2010-05-10 2014-08-21 The Regents Of The University Of California Endoribonuclease compositions and methods of use thereof
US20140200675A1 (en) * 2011-09-01 2014-07-17 Hip Innovation Technology, LLC Lined Femoral Cup
US9637739B2 (en) 2012-03-20 2017-05-02 Vilnius University RNA-directed DNA cleavage by the Cas9-crRNA complex
PE20190844A1 (es) 2012-05-25 2019-06-17 Emmanuelle Charpentier Modulacion de transcripcion con arn de direccion a adn generico
US9688971B2 (en) 2012-06-15 2017-06-27 The Regents Of The University Of California Endoribonuclease and methods of use thereof
HK1207111A1 (en) 2012-08-03 2016-01-22 加利福尼亚大学董事会 Methods and compositions for controlling gene expression by rna processing
DE202013012597U1 (de) * 2012-10-23 2017-11-21 Toolgen, Inc. Zusammensetzung zum Spalten einer Ziel-DNA, umfassend eine für die Ziel-DNA spezifische guide-RNA und eine Cas-Protein-codierende Nukleinsäure oder ein Cas-Protein, sowie deren Verwendung
EP2931898B1 (en) 2012-12-12 2016-03-09 The Broad Institute, Inc. Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
DK2898075T3 (en) 2012-12-12 2016-06-27 Broad Inst Inc CONSTRUCTION AND OPTIMIZATION OF IMPROVED SYSTEMS, PROCEDURES AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION
MX380562B (es) * 2012-12-12 2025-03-12 Broad Inst Inc Modificaciones de sistemas, métodos y composiciones guía optimizadas para la manipulación de secuencias.
EP4570817A3 (en) 2012-12-12 2025-09-24 The Broad Institute Inc. Crispr-cas component systems, methods and compositions for sequence manipulation
WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
RU2018122288A (ru) * 2013-03-14 2019-03-06 Карибо Биосайенсиз, Инк. Композиции и способы с участием нуклеиновых кислот, нацеленных на нуклеиновые кислоты
AU2014350051A1 (en) 2013-11-18 2016-07-07 Crispr Therapeutics Ag CRISPR-Cas system materials and methods
WO2015089364A1 (en) * 2013-12-12 2015-06-18 The Broad Institute Inc. Crystal structure of a crispr-cas system, and uses thereof
US20150376586A1 (en) 2014-06-25 2015-12-31 Caribou Biosciences, Inc. RNA Modification to Engineer Cas9 Activity
SI3250691T1 (sl) * 2015-01-28 2023-10-30 Caribou Biosciences, Inc. Hibridni dna/rna-polinukleotidi crispr in postopki za uporabo
US9580727B1 (en) * 2015-08-07 2017-02-28 Caribou Biosciences, Inc. Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides
JP6707133B2 (ja) * 2015-12-04 2020-06-10 カリブー・バイオサイエンシーズ・インコーポレイテッド 操作された核酸標的化核酸

Also Published As

Publication number Publication date
EP3371310A1 (en) 2018-09-12
RU2018117360A (ru) 2020-01-09
KR20180085795A (ko) 2018-07-27
DK3371310T3 (da) 2019-08-05
IL259148B (en) 2021-08-31
CN108473981B (zh) 2022-04-12
EP3564371A1 (en) 2019-11-06
NZ756843A (en) 2021-07-30
CA3004757A1 (en) 2017-06-08
CA3004757C (en) 2020-07-21
US20180119173A1 (en) 2018-05-03
HK1252755A1 (en) 2019-05-31
AU2016363024A1 (en) 2018-05-17
BR112018010429A2 (pt) 2018-11-27
US20170159073A1 (en) 2017-06-08
JP6707133B2 (ja) 2020-06-10
AU2019240724B2 (en) 2021-02-18
CN108473981A (zh) 2018-08-31
AU2019240724A1 (en) 2019-10-24
MX2018005392A (es) 2019-05-30
KR102093570B1 (ko) 2020-03-25
US9771600B2 (en) 2017-09-26
EP3564371B1 (en) 2020-05-27
US10100333B2 (en) 2018-10-16
ZA201802968B (en) 2019-02-27
SG11201803593QA (en) 2018-06-28
MX391311B (es) 2025-03-21
EP3371310B1 (en) 2019-05-01
NZ742040A (en) 2019-08-30
AU2016363024B2 (en) 2020-01-30
US9970029B1 (en) 2018-05-15
ES2735773T3 (es) 2019-12-20
WO2017096328A1 (en) 2017-06-08
US20190100775A1 (en) 2019-04-04
JP2019500867A (ja) 2019-01-17
US20180251788A1 (en) 2018-09-06
HK1252755B (en) 2020-02-07
IL259148A (en) 2018-07-31
US11505808B2 (en) 2022-11-22

Similar Documents

Publication Publication Date Title
RU2018117360A3 (ru)
BR112018004996A2 (ru)
BR0003189B1 (ru)
BR0005041B1 (ru)
BR0007487B1 (ru)
BR0007468B1 (ru)
BR0006866B1 (ru)
BR0006854B1 (ru)
BR0008789B1 (ru)
BR0006634B1 (ru)
BR0007688B1 (ru)
BR0003166B1 (ru)
BR0008132B1 (ru)
BR0004687B1 (ru)
BR0003928B1 (ru)
BR0003751B1 (ru)
BR0003746B1 (ru)
BR0008719B1 (ru)
BR0003686B1 (ru)
BR0003401B1 (ru)
BR0009757B1 (ru)
BR0003208B1 (ru)
BR0008604B1 (ru)
BR0002874B1 (ru)
BR0007672B1 (ru)

Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20200421