RU2015123679A - Продукты для ухода за полостью рта, содержащие комплекс четырехосновной цинк-аминокислота-галогенид - Google Patents
Продукты для ухода за полостью рта, содержащие комплекс четырехосновной цинк-аминокислота-галогенид Download PDFInfo
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- RU2015123679A RU2015123679A RU2015123679A RU2015123679A RU2015123679A RU 2015123679 A RU2015123679 A RU 2015123679A RU 2015123679 A RU2015123679 A RU 2015123679A RU 2015123679 A RU2015123679 A RU 2015123679A RU 2015123679 A RU2015123679 A RU 2015123679A
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- Prior art keywords
- composition
- amino acid
- composition according
- halide
- orally acceptable
- Prior art date
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- 239000000203 mixture Substances 0.000 claims 18
- 150000001413 amino acids Chemical class 0.000 claims 7
- 239000011701 zinc Substances 0.000 claims 7
- 229910052725 zinc Inorganic materials 0.000 claims 7
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 4
- 208000002925 dental caries Diseases 0.000 claims 4
- 150000004820 halides Chemical class 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- -1 zinc halide Chemical class 0.000 claims 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 229940112822 chewing gum Drugs 0.000 claims 2
- 235000015218 chewing gum Nutrition 0.000 claims 2
- 150000001805 chlorine compounds Chemical group 0.000 claims 2
- 210000003298 dental enamel Anatomy 0.000 claims 2
- 230000003628 erosive effect Effects 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000019634 flavors Nutrition 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 208000007565 gingivitis Diseases 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- 210000000214 mouth Anatomy 0.000 claims 2
- 239000002324 mouth wash Substances 0.000 claims 2
- 229940051866 mouthwash Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229920006318 anionic polymer Polymers 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 239000007844 bleaching agent Substances 0.000 claims 1
- 230000001680 brushing effect Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000000551 dentifrice Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 159000000001 potassium salts Chemical class 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/58—Metal complex; Coordination compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (18)
1. Композиция для ухода за полостью рта, содержащая четырехосновной цинк галогенид и аминокислоту.
2. Композиция по п. 1, в которой галогенид выбран из хлорида, бромида и фторида.
3. Композиция по п. 1 или 2, где галогенид представляет собой хлорид.
4. Композиция по п. 1 или 2, где аминокислота выбрана из лизина, глицина и аргинина в свободной форме или в форме перорально приемлемой кислотно-аддитивной соли.
5. Композиция по п. 1 или 2, где аминокислота представляет собой основную аминокислоту в свободной форме или в форме перорально приемлемой соли.
6. Композиция по п. 1 или 2, где количество цинка составляет 0,05-4 мас.%.
7. Композиция по п. 1 или 2, где четырехосновный цинк, галогенид и аминокислота находятся в комплексе.
8. Композиция по п. 1 или 2, где четырехосновной цинк, галогенид растворяют в составе, но осуществляется осаждение цинка при использовании и разбавлении слюной и/или промыванием.
9. Композиция по п. 1 или 2 в виде зубной пасты, геля, жидкости для полоскания рта, порошка, крема, полоски или жевательной резинки.
10. Композиция по п. 1 или 2 в перорально приемлемом основании, например жидкости для полоскания рта, геля или основе средства для чистки зубов.
11. Композиция по п. 1 или 2, дополнительно содержащая эффективное количество источника фторид-ионов.
12. Композиция по п. 1 или 2, содержащая перорально приемлемое основание, включающее ингредиенты, выбранные из одного или более из абразивных веществ, буферных средств, увлажнителей, поверхностно-активных веществ, загустителей, полосок жевательной резинки или фрагментов, освежителей для полости рта, вкусовых добавок, ароматизаторов, окрашивающих средств, антибактериальных средств, отбеливающих средств,
средств, которые препятствуют или предотвращают прикрепление бактерий, источников кальция, источников фосфата, перорально приемлемых солей калия, анионных полимеров.
13. Композиция по п. 1 или 2, в которой значение рН композиции составляет от рН 6 до рН 8.
14. Композиция по п. 1 или 2 для применения для уменьшения и замедления кислотной эрозии на эмали, для уменьшения образованными бактериями биопленки и зубного налета, для уменьшения гингивита, для ингибирования кариеса зубов и образования полостей и/или для уменьшения дентинной гиперчувствительности.
15. Применение четырехосновного цинк галогенида вместе с аминокислотой для получения композиции для ухода за полостью рта.
16. Применение по п. 15, где четырехосновный цинк галогенид вместе с аминокислотой находятся в комплексе.
17. Способ лечения или уменьшения эрозии зубной эмали, чистки зубов, уменьшения образованными бактериями биопленки и зубного налета, уменьшения гингивита, ингибирования кариеса зубов и образования полостей и/или уменьшения дентинной гиперчувствительности, включающий нанесение композиции по любому из пп. 1-14 в ротовую полость индивида, нуждающегося в этом.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/070521 WO2014098825A1 (en) | 2012-12-19 | 2012-12-19 | Oral care products comprising a tetrabasic zinc - amino acid - halide complex |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015123679A true RU2015123679A (ru) | 2017-01-23 |
| RU2625763C2 RU2625763C2 (ru) | 2017-07-18 |
Family
ID=47501519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015123679A RU2625763C2 (ru) | 2012-12-19 | 2012-12-19 | Продукты для ухода за полостью рта, содержащие комплекс четырехосновный цинк-аминокислота-галогенид |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9775792B2 (ru) |
| EP (1) | EP2934442B1 (ru) |
| KR (1) | KR20150097494A (ru) |
| CN (1) | CN104853726B (ru) |
| AR (1) | AR094202A1 (ru) |
| AU (1) | AU2012397266B2 (ru) |
| BR (1) | BR112015014253B1 (ru) |
| CA (1) | CA2892421C (ru) |
| IL (1) | IL239531A0 (ru) |
| MX (1) | MX352357B (ru) |
| PH (1) | PH12015501435A1 (ru) |
| RU (1) | RU2625763C2 (ru) |
| TW (2) | TWI555534B (ru) |
| WO (1) | WO2014098825A1 (ru) |
| ZA (1) | ZA201503849B (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2892468C (en) | 2012-12-19 | 2019-10-08 | Colgate-Palmolive Company | Oral care products comprising tetrabasic zinc chloride and trimethylglycine |
| US10188112B2 (en) | 2012-12-19 | 2019-01-29 | Colgate-Palmolive Company | Personal cleansing compositions containing zinc amino acid/trimethylglycine halide |
| KR20150097492A (ko) | 2012-12-19 | 2015-08-26 | 콜게이트-파아므올리브캄파니 | 산화아연과 트리메틸글리신을 포함하는 구강 관리 용품 |
| KR20150097494A (ko) | 2012-12-19 | 2015-08-26 | 콜게이트-파아므올리브캄파니 | 4 염기성 아연 아미노산 할로겐화물 착물을 포함하는 구강 관리 제품 |
| AU2012397263B2 (en) | 2012-12-19 | 2015-09-24 | Colgate-Palmolive Company | Zinc amino acid halide mouthwashes |
| EP2934443B1 (en) * | 2012-12-19 | 2017-09-06 | Colgate-Palmolive Company | Oral care compositions comprising zinc amino acid halides |
| US9504858B2 (en) | 2012-12-19 | 2016-11-29 | Colgate-Palmolive Company | Zinc amino acid halide complex with cysteine |
| EP2934695B1 (en) | 2012-12-19 | 2016-11-30 | Colgate-Palmolive Company | Antiperspirant products with protein and antiperspirant salts |
| US9750670B2 (en) | 2012-12-19 | 2017-09-05 | Colgate-Palmolive Company | Zinc amino acid complex with cysteine |
| KR20150094651A (ko) | 2012-12-19 | 2015-08-19 | 콜게이트-파아므올리브캄파니 | 아연-아미노산 착체를 포함하는 경구 겔 |
| EP2934445B1 (en) | 2012-12-19 | 2017-10-04 | Colgate-Palmolive Company | Teeth whitening methods, visually perceptible signals and compositions therefor comprising zinc amino acid halides |
| BR112015014445A2 (pt) | 2012-12-19 | 2017-07-11 | Colgate Palmolive Co | complexo de zinco-lisina |
| US9498421B2 (en) | 2012-12-19 | 2016-11-22 | Colgate-Palmolive Company | Two component compositions containing tetrabasic zinc-amino acid halide complexes and cysteine |
| RU2638791C2 (ru) | 2012-12-19 | 2017-12-15 | Колгейт-Палмолив Компани | Композиция с галогенидными предшественниками аминокислоты/триметилглицина цинка |
| BR112015014501B1 (pt) | 2012-12-19 | 2019-04-02 | Colgate-Palmolive Company | Composição de cuidado pessoal para aplicação na pele ou cabelo e uso de um complexo de halogeneto de zinco X |
| US9675823B2 (en) | 2012-12-19 | 2017-06-13 | Colgate-Palmolive Company | Two component compositions containing zinc amino acid halide complexes and cysteine |
| RU2016124156A (ru) * | 2013-12-19 | 2018-01-24 | Колгейт-Палмолив Компани | Композиция для ухода за полостью рта, устраняющая неприятный запах |
| EP3157935B1 (en) | 2014-06-18 | 2018-08-15 | Colgate-Palmolive Company | Synthesis of zinc-lysine complex from zinc chloride |
| CN106456483B (zh) * | 2014-06-18 | 2019-08-20 | 高露洁-棕榄公司 | 包含锌-氨基酸络合物和磷酸盐的洁牙剂 |
| US9718843B2 (en) | 2014-06-18 | 2017-08-01 | Colgate-Palmolive Company | Low pH sysnthesis of zinc-lysine complex |
| CN107106427B (zh) | 2014-12-26 | 2020-12-29 | 高露洁-棕榄公司 | 磷酸锌络合物 |
| CN107106425B (zh) | 2014-12-26 | 2021-01-22 | 高露洁-棕榄公司 | 具有磷酸锌活性物的个人护理组合物 |
| CA2971578A1 (en) | 2014-12-26 | 2016-06-30 | Colgate-Palmolive Company | Oral care composition comprising a zinc polyphosphate complex |
| BR112017012806B1 (pt) | 2014-12-26 | 2020-11-17 | Colgate-Palmolive Company | complexo de polifosfato de zinco solúvel e método de produção de polifosfato de zinco |
| US20170157013A1 (en) * | 2015-12-07 | 2017-06-08 | Colgate-Palmolive Company | Metal Amino Acid Complexes for Bacterial Aggregation |
| CN106994103B (zh) * | 2016-01-26 | 2021-08-10 | 白育纶 | 漱口水组成物 |
| WO2018063492A1 (en) | 2016-09-28 | 2018-04-05 | Colgate-Palmolive Company | Oral care compositions and dispensing system therefor |
| US10058493B2 (en) | 2016-12-21 | 2018-08-28 | Colgate-Palmolive Company | Oral care compositions and methods of use |
| EP3672563B1 (en) * | 2017-12-13 | 2025-12-03 | Colgate-Palmolive Company | Dentifrice comprising zinc - amino acid complex |
| US11395793B2 (en) | 2018-10-24 | 2022-07-26 | Colgate-Palmolive Company | Zinc—amino acid—lauryl sulfate complex with antimicrobial activity |
| WO2020131665A1 (en) * | 2018-12-21 | 2020-06-25 | Colgate-Palmolive Company | Zinc-arginine-halide complex |
| US11229591B2 (en) | 2018-12-21 | 2022-01-25 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| US11117906B2 (en) | 2018-12-21 | 2021-09-14 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| US11091502B2 (en) | 2018-12-21 | 2021-08-17 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| CN113260352A (zh) * | 2018-12-26 | 2021-08-13 | 高露洁-棕榄公司 | 口腔护理组合物及使用方法 |
| EP3838252A1 (en) * | 2019-12-06 | 2021-06-23 | Colgate-Palmolive Company | Oral care product and method of use and manufacture thereof |
Family Cites Families (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE735096C (de) | 1940-12-09 | 1943-05-06 | Ig Farbenindustrie Ag | Verfahren zur Herstellung von Sulfonsaeuren |
| US2527686A (en) | 1945-12-26 | 1950-10-31 | Max H Sandberg | Mouthwash |
| US2503280A (en) | 1947-10-24 | 1950-04-11 | Du Pont | Azo catalysts in preparation of sulfonic acids |
| US2507088A (en) | 1948-01-08 | 1950-05-09 | Du Pont | Sulfoxidation process |
| US2893918A (en) | 1957-04-24 | 1959-07-07 | Harold A Abramson | Deodorant composition |
| FR1247957A (fr) | 1958-09-28 | 1960-12-09 | Ajinomoto Kk | Procédé de séparation continue d'aminoacides racémiques |
| US3320174A (en) | 1964-04-20 | 1967-05-16 | Colgate Palmolive Co | Detergent composition |
| US3372188A (en) | 1965-03-12 | 1968-03-05 | Union Oil Co | Sulfoxidation process in the presence of sulfur trioxide |
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US3678154A (en) | 1968-07-01 | 1972-07-18 | Procter & Gamble | Oral compositions for calculus retardation |
| US3535421A (en) | 1968-07-11 | 1970-10-20 | Procter & Gamble | Oral compositions for calculus retardation |
| US3741911A (en) | 1970-12-21 | 1973-06-26 | Hart Chemical Ltd | Phosphate-free detergent composition |
| US3959458A (en) | 1973-02-09 | 1976-05-25 | The Procter & Gamble Company | Oral compositions for calculus retardation |
| US3937807A (en) | 1973-03-06 | 1976-02-10 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| US3862307A (en) | 1973-04-09 | 1975-01-21 | Procter & Gamble | Dentifrices containing a cationic therapeutic agent and improved silica abrasive |
| US3941818A (en) | 1973-08-20 | 1976-03-02 | Zinpro Corporation | 1:1 Zinc methionine complexes |
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| US4340583A (en) | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4339432A (en) * | 1979-06-20 | 1982-07-13 | Lever Brothers Company | Oral mouthwash containing zinc and glycine |
| CA1139229A (en) | 1979-06-20 | 1983-01-11 | Thomas W. Ritchey | Zinc salt with glycine in oral composition |
| US4316824A (en) | 1980-06-26 | 1982-02-23 | The Procter & Gamble Company | Liquid detergent composition containing alkyl sulfate and alkyl ethoxylated sulfate |
| JPS57158724A (en) | 1981-03-26 | 1982-09-30 | Shiseido Co Ltd | Antimicrobial composition |
| US4565693A (en) | 1981-11-09 | 1986-01-21 | Colgate-Palmolive Company | Deodorant composition |
| US4487757A (en) | 1981-12-28 | 1984-12-11 | Colgate-Palmolive Company | Dispensing container of toothpaste which effervesces during toothbrushing |
| IL64700A0 (en) | 1982-01-01 | 1982-03-31 | Binderman Itzhak | Dental care compositions |
| US4885155A (en) | 1982-06-22 | 1989-12-05 | The Procter & Gamble Company | Anticalculus compositions using pyrophosphate salt |
| DE3238118A1 (de) | 1982-10-14 | 1984-04-19 | Verla-Pharm, Arzneimittelfabrik Apotheker H.J. v. Ehrlich GmbH & Co KG, 8132 Tutzing | Verfahren zur herstellung von komplexverbindungen aus aminodicarbonsaeuren, zweiwertigen metallionen und halogenidionen |
| US4687663B1 (en) | 1983-03-01 | 1997-10-07 | Chesebrough Ponds Usa Co | Dental preparation article and method for storage and delivery thereof |
| CA1243952A (en) * | 1984-06-11 | 1988-11-01 | John C. Godfrey | Flavor of zinc supplements for oral use |
| US4599152A (en) | 1985-05-24 | 1986-07-08 | Albion Laboratories | Pure amino acid chelates |
| US5192531A (en) | 1988-12-29 | 1993-03-09 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| US5188821A (en) | 1987-01-30 | 1993-02-23 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
| US4866161A (en) | 1987-08-24 | 1989-09-12 | University Of South Alabama | Inhibition of tartar deposition by polyanionic/hydrophobic peptides and derivatives thereof which have a clustered block copolymer structure |
| US5004597A (en) | 1987-09-14 | 1991-04-02 | The Procter & Gamble Company | Oral compositions comprising stannous flouride and stannous gluconate |
| US4842847A (en) | 1987-12-21 | 1989-06-27 | The B. F. Goodrich Company | Dental calculus inhibiting compositions |
| US5061815A (en) | 1988-07-06 | 1991-10-29 | Zinpro Corporation | Metal lysine complexes and method for producing metal lysine complexes |
| JP2595752B2 (ja) * | 1990-03-27 | 1997-04-02 | 三菱電機株式会社 | 磁気記録再生装置 |
| US5156845A (en) | 1990-05-04 | 1992-10-20 | Colgate-Palmolive Company | Dry mouth lozenge |
| GB2243775A (en) * | 1990-05-09 | 1991-11-13 | Unilever Plc | Oral compositions |
| JPH0578243A (ja) | 1990-12-11 | 1993-03-30 | Shiseido Co Ltd | 鎮痒剤及び鎮痒組成物 |
| GB9107833D0 (en) | 1991-04-12 | 1991-05-29 | Unilever Plc | Treatment of periodontitis |
| US5643559A (en) | 1991-10-30 | 1997-07-01 | Colgate-Palmolive Company | Deodorant compositions comprising inhibitors of odor-producing axillary bacterial exoenzymes |
| US5504055A (en) | 1994-03-15 | 1996-04-02 | J.H. Biotech, Inc. | Metal amino acid chelate |
| US5707679A (en) | 1994-09-30 | 1998-01-13 | Kemin Industries, Inc. | Metal propionates for use as animal feed supplements |
| DE69623381T2 (de) | 1995-05-03 | 2003-01-09 | Unilever N.V., Rotterdam | Klare Gelzahnpasta |
| US5714447A (en) | 1996-01-24 | 1998-02-03 | Church & Dwight Co., Inc. | Deodorant soap or detergent composition containing a zinc compound and a polyamine |
| US5698724A (en) | 1996-04-30 | 1997-12-16 | Zinpro Corporation | Amino acid metal complexes using hydrolyzed protein as the amino acid source and methods re same |
| US6121315A (en) | 1996-09-20 | 2000-09-19 | Warner-Lambert Company | Oral compositions containing a zinc compound |
| GB9622659D0 (en) | 1996-10-31 | 1997-01-08 | Unilever Plc | Hair treatment composition |
| US5897891A (en) | 1996-11-18 | 1999-04-27 | Godfrey; John C. | Flavorful zinc compositions for oral use incorporating copper |
| FI106923B (fi) | 1997-01-03 | 2001-05-15 | Cultor Ltd Finnsugar Bioproduc | Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa |
| US5993784A (en) | 1997-07-24 | 1999-11-30 | Whitehill Oral Technologies | Low foaming therapeutic toothpastes with improved cleaning and abrasion performance |
| DK176196B1 (da) | 1997-10-07 | 2007-01-08 | Ejvind Jersie Pedersen | Mundhygejnepræparat til behandling af halitosis samt anvendelse af et chelat omfattende en metaliondel og en aminosyredel som en komponent i præparatet |
| AU760870B2 (en) | 1998-06-09 | 2003-05-22 | Unger, Martin G. Dr. | Method and composition for the treatment of epidermal irritations and infections |
| US6169118B1 (en) * | 1998-11-12 | 2001-01-02 | Block Drug Company, Inc. | Flavor blend for masking unpleasant taste of zinc compounds |
| US6558710B1 (en) | 1999-06-14 | 2003-05-06 | Helen Rebecca Godfrey | Topical zinc compositions and methods of use |
| US6685920B2 (en) | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| US7164035B2 (en) | 2000-01-07 | 2007-01-16 | Newsome David A | Zinc-monocysteine complex and method of using zinc-cysteine complexes |
| JP3490950B2 (ja) | 2000-03-15 | 2004-01-26 | 三洋電機株式会社 | ２シリンダ型２段圧縮式ロータリーコンプレッサ |
| DE10160933B4 (de) | 2001-12-12 | 2018-06-21 | Evonik Degussa Gmbh | Zubereitungen mit desodorierender Wirkung, enthaltend das Zinksalz der Ricinolsäure und mindestens eine aminofunktionelle Aminosäure |
| US6670494B1 (en) | 2001-12-17 | 2003-12-30 | J H Brotech, Inc. | Method for preparation of metal organic acid chelates |
| US20040033916A1 (en) | 2002-06-28 | 2004-02-19 | Kuzmin Vladimir Semenovich | Disinfecting composition |
| JP2004175790A (ja) | 2002-11-12 | 2004-06-24 | Arita Junichi | α−グルコシダーゼ阻害作用を有する亜鉛含有物 |
| US7022351B2 (en) | 2003-01-14 | 2006-04-04 | Zinpro Corporation | Composition for supplementing animals with solutions of essential metal amino acid complexes |
| US20040198998A1 (en) | 2003-04-04 | 2004-10-07 | Marian Holerca | Glycine-free antiperspirant salts with betaine for enhanced cosmetic products |
| US7270806B2 (en) | 2004-07-27 | 2007-09-18 | Coty S.A. | Liquid stick antiperspirant |
| US7700079B2 (en) | 2005-09-26 | 2010-04-20 | Jamie Collins Doss | Therapeutic soap product with UV protection |
| WO2007063507A2 (en) * | 2005-11-29 | 2007-06-07 | The Procter & Gamble Company | Dentifrice composition comprising binder system comprising hydrophilic clay material |
| CN101316571A (zh) * | 2005-11-29 | 2008-12-03 | 宝洁公司 | 不含磨料的洁齿剂组合物 |
| CN100366539C (zh) | 2006-05-25 | 2008-02-06 | 黄逸强 | 一种微量元素添加剂碱式氯化锌的制备方法 |
| DE102006040302A1 (de) | 2006-08-29 | 2008-03-20 | Henkel Kgaa | Antitranspirant- und Deodorant-Zusammensetzungen mit verbesserter Pflegewirkung |
| EP1935395B1 (en) | 2006-12-20 | 2013-06-05 | Unilever PLC | Oral composition |
| US8247398B2 (en) | 2007-02-17 | 2012-08-21 | Ssv Therapeutics, Inc. | Zinc complexes of natural amino acids for treating elevated copper caused toxicities |
| JP2009084201A (ja) | 2007-09-28 | 2009-04-23 | Riken Koryo Kogyo Kk | パーマネントウェーブ剤用消臭処理剤並びにこれを含有するパーマネントウェーブ剤 |
| JP2011519969A (ja) | 2008-05-12 | 2011-07-14 | タグラ バイオテクノロジーズ リミテッド | マイクロカプセル封入着色剤を含む局所適用のための組成物 |
| CN101289412B (zh) * | 2008-05-23 | 2012-05-23 | 南昌大学 | 苏氨酸锌螯合物的制备方法 |
| US20100021573A1 (en) | 2008-07-22 | 2010-01-28 | Michael J Gonzalez | Compositions and methods for the prevention of cardiovascular disease |
| JP2010132639A (ja) | 2008-11-10 | 2010-06-17 | Nikko Chemical Co Ltd | Ｄｎａ損傷抑制剤及びマトリックスメタロプロテアーゼ−１産生抑制剤 |
| CA2766649C (en) | 2009-06-24 | 2016-08-23 | Charles N.S. Soparkar | Zinc supplementation to increase responsiveness to metalloprotease therapy |
| CN101606639B (zh) | 2009-07-20 | 2012-07-25 | 曹江山 | 一种保育猪浓缩饲料 |
| RU2491912C1 (ru) | 2009-09-30 | 2013-09-10 | Колгейт-Палмолив Компани | Композиция антиперспиранта/дезодоранта |
| MY159488A (en) | 2009-10-29 | 2017-01-13 | Colgate Palmolive Co | Dentifrice comprising stannous fluoride plus zinc citrate and low levels of water |
| TWI458497B (zh) | 2010-01-13 | 2014-11-01 | Colgate Palmolive Co | 口腔組成物中氧化鋅薄膜之安定化 |
| SG183905A1 (en) * | 2010-03-31 | 2012-10-30 | Colgate Palmolive Co | Oral care composition |
| CN103156073B (zh) | 2011-12-13 | 2015-02-18 | 北京东方联鸣科技发展有限公司 | 奶牛产后营养补充剂 |
| CN103535536A (zh) | 2012-07-15 | 2014-01-29 | 新沂市佳威饲料有限公司 | 一种哺乳母猪饲料的配制方法 |
| RU2638791C2 (ru) | 2012-12-19 | 2017-12-15 | Колгейт-Палмолив Компани | Композиция с галогенидными предшественниками аминокислоты/триметилглицина цинка |
| WO2014204439A1 (en) | 2013-06-18 | 2014-12-24 | Colgate-Palmolive Company | Zinc amino acid halide complex with cysteine |
| US10494589B2 (en) | 2012-12-19 | 2019-12-03 | Colgate-Palmolive Company | Method for indicating time for washing or indicating delivery of antibacterial agent |
| WO2014098821A1 (en) | 2012-12-19 | 2014-06-26 | Colgate-Palmolive Company | Method for indicating time for washing or indicating delivery of antibacterial agent |
| KR20150094651A (ko) | 2012-12-19 | 2015-08-19 | 콜게이트-파아므올리브캄파니 | 아연-아미노산 착체를 포함하는 경구 겔 |
| EP2934445B1 (en) | 2012-12-19 | 2017-10-04 | Colgate-Palmolive Company | Teeth whitening methods, visually perceptible signals and compositions therefor comprising zinc amino acid halides |
| EP2934695B1 (en) | 2012-12-19 | 2016-11-30 | Colgate-Palmolive Company | Antiperspirant products with protein and antiperspirant salts |
| MY170532A (en) | 2012-12-19 | 2019-08-14 | Colgate Palmolive Co | Zinc amino acid complex with cysteine |
| AU2012397263B2 (en) | 2012-12-19 | 2015-09-24 | Colgate-Palmolive Company | Zinc amino acid halide mouthwashes |
| KR20150097492A (ko) | 2012-12-19 | 2015-08-26 | 콜게이트-파아므올리브캄파니 | 산화아연과 트리메틸글리신을 포함하는 구강 관리 용품 |
| EP2934443B1 (en) | 2012-12-19 | 2017-09-06 | Colgate-Palmolive Company | Oral care compositions comprising zinc amino acid halides |
| BR112015014501B1 (pt) | 2012-12-19 | 2019-04-02 | Colgate-Palmolive Company | Composição de cuidado pessoal para aplicação na pele ou cabelo e uso de um complexo de halogeneto de zinco X |
| BR112015014445A2 (pt) | 2012-12-19 | 2017-07-11 | Colgate Palmolive Co | complexo de zinco-lisina |
| KR20150097494A (ko) | 2012-12-19 | 2015-08-26 | 콜게이트-파아므올리브캄파니 | 4 염기성 아연 아미노산 할로겐화물 착물을 포함하는 구강 관리 제품 |
-
2012
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- 2012-12-19 EP EP12809991.8A patent/EP2934442B1/en active Active
- 2012-12-19 CA CA2892421A patent/CA2892421C/en active Active
- 2012-12-19 WO PCT/US2012/070521 patent/WO2014098825A1/en not_active Ceased
- 2012-12-19 BR BR112015014253-2A patent/BR112015014253B1/pt not_active IP Right Cessation
- 2012-12-19 US US14/653,882 patent/US9775792B2/en active Active
- 2012-12-19 CN CN201280077890.5A patent/CN104853726B/zh not_active Expired - Fee Related
- 2012-12-19 AU AU2012397266A patent/AU2012397266B2/en not_active Ceased
- 2012-12-19 MX MX2015007875A patent/MX352357B/es active IP Right Grant
- 2012-12-19 RU RU2015123679A patent/RU2625763C2/ru active
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2013
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- 2013-12-02 TW TW104138181A patent/TW201630587A/zh unknown
- 2013-12-19 AR ARP130104936A patent/AR094202A1/es unknown
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- 2015-06-18 IL IL239531A patent/IL239531A0/en unknown
- 2015-06-19 PH PH12015501435A patent/PH12015501435A1/en unknown
Also Published As
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|---|---|
| IL239531A0 (en) | 2015-08-31 |
| EP2934442B1 (en) | 2016-11-30 |
| AU2012397266A1 (en) | 2015-06-11 |
| ZA201503849B (en) | 2017-09-27 |
| KR20150097494A (ko) | 2015-08-26 |
| CN104853726B (zh) | 2017-10-24 |
| TW201630587A (zh) | 2016-09-01 |
| RU2625763C2 (ru) | 2017-07-18 |
| CA2892421A1 (en) | 2014-06-26 |
| US9775792B2 (en) | 2017-10-03 |
| MX2015007875A (es) | 2015-09-28 |
| EP2934442A1 (en) | 2015-10-28 |
| TWI555534B (zh) | 2016-11-01 |
| CN104853726A (zh) | 2015-08-19 |
| WO2014098825A1 (en) | 2014-06-26 |
| MX352357B (es) | 2017-11-22 |
| AU2012397266B2 (en) | 2015-09-24 |
| AR094202A1 (es) | 2015-07-15 |
| CA2892421C (en) | 2019-10-01 |
| PH12015501435A1 (en) | 2015-09-14 |
| BR112015014253B1 (pt) | 2019-04-09 |
| US20150328111A1 (en) | 2015-11-19 |
| BR112015014253A2 (pt) | 2017-07-11 |
| TW201438749A (zh) | 2014-10-16 |
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