RU2012136147A - Антимикробные агенты и способы их применения - Google Patents
Антимикробные агенты и способы их применения Download PDFInfo
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- RU2012136147A RU2012136147A RU2012136147/15A RU2012136147A RU2012136147A RU 2012136147 A RU2012136147 A RU 2012136147A RU 2012136147/15 A RU2012136147/15 A RU 2012136147/15A RU 2012136147 A RU2012136147 A RU 2012136147A RU 2012136147 A RU2012136147 A RU 2012136147A
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- 239000004599 antimicrobial Substances 0.000 title claims abstract 3
- 239000003795 chemical substances by application Substances 0.000 claims abstract 41
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract 14
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract 11
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims abstract 8
- 150000002978 peroxides Chemical class 0.000 claims abstract 6
- 239000002738 chelating agent Substances 0.000 claims abstract 4
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract 4
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract 4
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract 4
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000002253 acid Substances 0.000 claims abstract 2
- 150000007513 acids Chemical class 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000000813 microbial effect Effects 0.000 claims 6
- 208000015181 infectious disease Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 1
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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Abstract
1. Антимикробный агент, содержащий:(a) воду;(b) низкомолекулярный спирт;(c) пероксид или пероксидобразующий агент; и(d) хелатирующий агент.2. Агент по п.1, отличающийся тем, что спирт включает этанол.3. Агент по п.1, отличающийся тем, что спирт присутствует в указанном агенте в концентрации, составляющей от приблизительно 1% до приблизительно 95% по объему.4. Агент по п.3, отличающийся тем, что концентрация спирта составляет от приблизительно 20% до приблизительно 60% по объему.5. Агент по п.4, отличающийся тем, что концентрация спирта составляет приблизительно 50% по объему.6. Агент по п.1, отличающийся тем, что хелатирующий агент включает этилендиаминтетрауксусную кислоту (ЭДТА) и кислоты и соли указанного соединения.7. Агент по п.6, отличающийся тем, что ЭДТА присутствует в концентрации, составляющей от приблизительно 5 мг/мл до приблизительно 50 мг/мл.8. Агент по п.7, отличающийся тем, что ЭДТА присутствует в концентрации, составляющей приблизительно 10 мг/мл.9. Агент по п.1, отличающийся тем, что пероксид или пероксидобразующий агент включает перекись водорода (HO).10. Агент по п.9, отличающийся тем, что HOприсутствует в концентрации, составляющей от приблизительно 0,05% до приблизительно 40% по объему.11. Агент по п.10, отличающийся тем, что HOприсутствует в концентрации, составляющей от приблизительно 0,05% до приблизительно 10% по объему.12. Агент по п.11, отличающийся тем, что HOприсутствует в концентрации, составляющей приблизительно 1,5% по объему.13. Агент по п.1, дополнительно включающий агент, повышающий вязкость.14. Агент по п.13, отличающийся тем, что агент, повышающий вязкость, включает гидроксипропилметилцеллюлозу (ГПМЦ).15. Агент по любому из пп.1-14, отли�
Claims (16)
1. Антимикробный агент, содержащий:
(a) воду;
(b) низкомолекулярный спирт;
(c) пероксид или пероксидобразующий агент; и
(d) хелатирующий агент.
2. Агент по п.1, отличающийся тем, что спирт включает этанол.
3. Агент по п.1, отличающийся тем, что спирт присутствует в указанном агенте в концентрации, составляющей от приблизительно 1% до приблизительно 95% по объему.
4. Агент по п.3, отличающийся тем, что концентрация спирта составляет от приблизительно 20% до приблизительно 60% по объему.
5. Агент по п.4, отличающийся тем, что концентрация спирта составляет приблизительно 50% по объему.
6. Агент по п.1, отличающийся тем, что хелатирующий агент включает этилендиаминтетрауксусную кислоту (ЭДТА) и кислоты и соли указанного соединения.
7. Агент по п.6, отличающийся тем, что ЭДТА присутствует в концентрации, составляющей от приблизительно 5 мг/мл до приблизительно 50 мг/мл.
8. Агент по п.7, отличающийся тем, что ЭДТА присутствует в концентрации, составляющей приблизительно 10 мг/мл.
9. Агент по п.1, отличающийся тем, что пероксид или пероксидобразующий агент включает перекись водорода (H2O2).
10. Агент по п.9, отличающийся тем, что H2O2 присутствует в концентрации, составляющей от приблизительно 0,05% до приблизительно 40% по объему.
11. Агент по п.10, отличающийся тем, что H2O2 присутствует в концентрации, составляющей от приблизительно 0,05% до приблизительно 10% по объему.
12. Агент по п.11, отличающийся тем, что H2O2 присутствует в концентрации, составляющей приблизительно 1,5% по объему.
13. Агент по п.1, дополнительно включающий агент, повышающий вязкость.
14. Агент по п.13, отличающийся тем, что агент, повышающий вязкость, включает гидроксипропилметилцеллюлозу (ГПМЦ).
15. Агент по любому из пп.1-14, отличающийся тем, что указанный агент является подходящим для уменьшения или подавления микробного роста, микробных инфекций, воспалительных заболеваний, вирусных заболеваний или состояний, возникших в результате или связанных с микробным ростом или инфекцией.
16. Агент по любому из пп.1-14, отличающийся тем, что указанный агент подходит для лечения микробного роста, микробных инфекций, воспалительных заболеваний, вирусных заболеваний или состояний, возникших в результате или связанных с микробным ростом или инфекцией.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29760910P | 2010-01-22 | 2010-01-22 | |
| US61/297,609 | 2010-01-22 | ||
| US41237510P | 2010-11-10 | 2010-11-10 | |
| US61/412,375 | 2010-11-10 | ||
| PCT/US2011/022150 WO2011091322A2 (en) | 2010-01-22 | 2011-01-21 | Antimicrobial agents and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2012136147A true RU2012136147A (ru) | 2014-02-27 |
| RU2570387C2 RU2570387C2 (ru) | 2015-12-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012136147/15A RU2570387C2 (ru) | 2010-01-22 | 2011-01-21 | Антимикробные агенты и способы их применения |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8846008B2 (ru) |
| EP (1) | EP2525803B1 (ru) |
| JP (2) | JP5866298B2 (ru) |
| KR (1) | KR101785130B1 (ru) |
| CN (1) | CN103108643B (ru) |
| AU (1) | AU2011207398B2 (ru) |
| BR (1) | BR112012018170B8 (ru) |
| CA (1) | CA2786880C (ru) |
| MX (1) | MX2012008482A (ru) |
| RU (1) | RU2570387C2 (ru) |
| SG (1) | SG182452A1 (ru) |
| WO (1) | WO2011091322A2 (ru) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9192449B2 (en) | 2007-04-02 | 2015-11-24 | C. R. Bard, Inc. | Medical component scrubbing device with detachable cap |
| US8336152B2 (en) | 2007-04-02 | 2012-12-25 | C. R. Bard, Inc. | Insert for a microbial scrubbing device |
| BRPI0811530B1 (pt) | 2007-05-14 | 2019-01-02 | Research Foundation Of State Univ Of New York | composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície |
| US8778387B2 (en) * | 2009-09-02 | 2014-07-15 | Hyprotek, Inc. | Antimicrobial medical dressings and protecting wounds and catheter sites |
| CN103108643B (zh) | 2010-01-22 | 2016-10-26 | 希普罗特克有限公司 | 包含过氧化物、醇和螯合剂的抗菌剂 |
| WO2013042140A2 (en) * | 2011-09-23 | 2013-03-28 | Manu Chaudhary | Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement |
| SG10201604170QA (en) * | 2011-11-28 | 2016-07-28 | Hyprotek Inc | Port and surface cleaning devices and techniques |
| US9039967B2 (en) | 2012-02-06 | 2015-05-26 | Hyprotek, Inc. | Antiseptic applicators and packaging techniques |
| WO2014087241A2 (en) * | 2012-12-05 | 2014-06-12 | Institut Pasteur | Methods of detecting biofilms from the palmitoylation of lipopolysaccharides |
| WO2015038731A1 (en) | 2013-09-12 | 2015-03-19 | The Johns Hopkins University | Biofilm formation to define risk for colon cancer |
| CN104146994A (zh) * | 2014-06-10 | 2014-11-19 | 苏州普洛赛医药科技有限公司 | 一种用于化学及高温灼伤的应急保护液剂及其制备方法 |
| WO2016149074A1 (en) * | 2015-03-13 | 2016-09-22 | The Regents Of The University Of California | Method for biofilm control and treatment |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| PT115056B (pt) * | 2018-10-04 | 2021-12-10 | Hovione Farm Sa | Formas amorfas de agentes quelantes e seus métodos de preparação |
| JP7168678B2 (ja) * | 2018-10-31 | 2022-11-09 | 富士フイルム株式会社 | 組成物、スプレー、ワイパー |
| EP3917584A1 (en) * | 2019-01-28 | 2021-12-08 | Hyprotek, Inc. | Antimicrobial composition with procoagulant, immunomodulatory, and tissue regenerative properties |
| CN110006724B (zh) * | 2019-04-17 | 2021-06-04 | 郑州安图生物工程股份有限公司 | 采用巴氏和革兰氏染色方法检测滴虫用试剂 |
| CN110024781A (zh) * | 2019-05-23 | 2019-07-19 | 昆明野水生物科技有限公司 | 一种在常温下能迅速杀灭芽孢的制剂及其应用 |
| BR112021024716A2 (pt) * | 2019-06-19 | 2022-02-08 | QBiotics Pty Ltd | Ruptura de biofilme |
| CN111264558A (zh) * | 2020-04-07 | 2020-06-12 | 河南省奥林特药业有限公司 | 一种抑制乙醇挥发的免洗凝胶消毒剂及其制备工艺 |
| KR102340910B1 (ko) * | 2020-07-21 | 2021-12-16 | 이난희 | 거품 촉진 욕실용 세정제 및 이의 제조방법 |
| JP2022043957A (ja) * | 2020-09-04 | 2022-03-16 | 中 木田 | 強力な殺芽胞能力を発揮するスチームクリーナー |
| WO2024173302A1 (en) | 2023-02-15 | 2024-08-22 | Hyprotek, Inc. | Closed sterile medication mixing and/or administration system with disinfection options |
Family Cites Families (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB350384A (en) | 1929-03-04 | 1931-06-04 | John Barnard Kirsch | Dressing for wounds ready for use |
| US4188234A (en) | 1965-08-24 | 1980-02-12 | Plains Chemical Development Co. | Chelation |
| US3607760A (en) | 1969-06-09 | 1971-09-21 | Edna M Mcintyre | Cleaning composition for pet stains |
| US3860348A (en) | 1973-06-06 | 1975-01-14 | Schick Inc | Applicator package for fluid products |
| US4291697A (en) | 1980-04-18 | 1981-09-29 | Stephen Georgevich | Cleaning and application device for medical purposes |
| US5046608A (en) | 1981-10-19 | 1991-09-10 | Laipply Thomas C | Combined fluid storage container and applicator device and method |
| US4440207A (en) | 1982-05-14 | 1984-04-03 | Baxter Travenol Laboratories, Inc. | Antibacterial protective cap for connectors |
| ATE67739T1 (de) | 1984-01-23 | 1991-10-15 | Thomas C Laipply | Alkoholwischer und verfahren. |
| US4564010A (en) | 1984-04-18 | 1986-01-14 | Daubert Coated Products Inc. | Pressure sensitive adhesive film for medical use |
| JPS6274364A (ja) | 1985-09-27 | 1987-04-06 | 株式会社 ニツシヨ− | 医療用具 |
| GB8622698D0 (en) | 1986-09-20 | 1986-10-29 | Smith & Nephew Ass | Dispenser |
| US4830856A (en) | 1987-01-27 | 1989-05-16 | Peppers James M | Chelation product |
| US4811847A (en) | 1988-03-14 | 1989-03-14 | Reif Thomas H | Urinary catheter package |
| US4954239A (en) | 1988-04-15 | 1990-09-04 | Mueller Louis H | Prefilled catheter tip syringe kit |
| US5438984A (en) | 1988-09-08 | 1995-08-08 | Sudor Partners | Apparatus and method for the collection of analytes on a dermal patch |
| US5041264A (en) | 1988-10-03 | 1991-08-20 | Williams Robert M | Method and apparatus for disinfecting objects |
| US5171523A (en) | 1988-10-03 | 1992-12-15 | Williams Robert M | Method and apparatus for disinfecting objects |
| US4893956A (en) | 1988-11-18 | 1990-01-16 | Blistex Inc. | Packaging for medicaments |
| US5015228A (en) | 1989-06-05 | 1991-05-14 | Eastman Kodak Company | Sterilizing dressing device and method for skin puncture |
| EP0544778A1 (en) | 1990-09-17 | 1993-06-09 | Medipro Sciences Limited | Bilayer wound dressing |
| JPH07500751A (ja) | 1991-11-06 | 1995-01-26 | ビオダーム・インコーポレイテツド | 密封包帯材及びアプリケーター |
| US5222600A (en) | 1992-07-28 | 1993-06-29 | Stoddard James T | Autoclave pouch |
| WO1994013209A1 (fr) | 1992-12-07 | 1994-06-23 | Hisamitsu Pharmaceutical Co., Inc. | Emplatre de test et procede de test |
| ATE232072T1 (de) | 1993-05-04 | 2003-02-15 | Lisa Fernandez Geng | Wundverband |
| US5454798A (en) | 1993-05-14 | 1995-10-03 | Mentor Corporation | Disposable urine bag |
| AU7256194A (en) | 1993-07-06 | 1995-02-06 | Leo J. Utecht | Personal protection apparatus |
| DE4332093C2 (de) | 1993-09-22 | 1995-07-13 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung |
| US5731275A (en) * | 1994-04-05 | 1998-03-24 | Universite De Montreal | Synergistic detergent and disinfectant combinations for decontaminating biofilm-coated surfaces |
| GB9411429D0 (en) | 1994-06-08 | 1994-07-27 | Seton Healthcare Group Plc | Wound dressings |
| US5556375A (en) | 1994-06-16 | 1996-09-17 | Hercules Incorporated | Wound dressing having a fenestrated base layer |
| US5569207A (en) | 1994-10-13 | 1996-10-29 | Quinton Instrument Company | Hydrocolloid dressing |
| US5554135A (en) | 1995-02-17 | 1996-09-10 | Menyhay; Steve Z. | Sterile medical injection port and cover method and apparatus |
| WO1996032142A1 (en) | 1995-04-12 | 1996-10-17 | Hopp Robert B | Skin patch for use in contact immunotherapy |
| MX9601936A (es) | 1995-07-07 | 1997-01-31 | Becton Dickinson Co | Una bandeja mejorada para la preparacion de la piel para uso en procedimientos quirurgicos. |
| US5976117A (en) | 1996-09-25 | 1999-11-02 | 3M Innovative Properties Company | Wound dressing |
| JPH10110268A (ja) | 1996-10-03 | 1998-04-28 | Nissin Electric Co Ltd | 医療用被覆材 |
| US20030007939A1 (en) * | 1998-07-31 | 2003-01-09 | Howard Murad | Pharmaceutical compositions and methods for managing dermatological conditions |
| US6071541A (en) | 1998-07-31 | 2000-06-06 | Murad; Howard | Pharmaceutical compositions and methods for managing skin conditions |
| US6168800B1 (en) | 1998-08-20 | 2001-01-02 | Medwrap Corporation | Antimcrobial multi-layer island dressing |
| JP2002529545A (ja) * | 1998-11-06 | 2002-09-10 | ユニベルシテ ドゥ モントリオール | バイオフィルムを除去するための改良型の殺菌性及び非殺菌性溶液 |
| FR2804601B1 (fr) | 2000-02-04 | 2002-04-26 | 3X Engineering | Dispositif d'application de principes actifs utilisables dans le domaine pharmaceutique ou cosmetique |
| US6455066B1 (en) | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
| WO2001095889A1 (en) | 2000-06-13 | 2001-12-20 | Hisamitsu Pharmaceutical Co., Inc. | Plaster |
| US7482021B1 (en) | 2001-05-11 | 2009-01-27 | Tison Kelley H | Two-sided wipe for cleaning and drying a skin surface |
| US8541472B2 (en) * | 2001-12-05 | 2013-09-24 | Aseptica, Inc. | Antiseptic compositions, methods and systems |
| GB2382775B (en) | 2001-12-06 | 2005-05-25 | Johnson & Johnson Medical Ltd | Controlled release therapeutic wound dressings |
| JP2004049540A (ja) | 2002-07-19 | 2004-02-19 | Chisso Corp | 抗菌性粘着フィルム及びそれを用いた救急絆創膏 |
| EP1393710A1 (en) * | 2002-08-21 | 2004-03-03 | The Procter & Gamble Company | A method of applying an oral composition |
| US9597067B2 (en) | 2002-10-04 | 2017-03-21 | Ethicon, Inc. | Packaged antimicrobial medical device and method of preparing same |
| US8112973B2 (en) | 2002-10-04 | 2012-02-14 | Ethicon, Inc. | Method of making a packaged antimicrobial suture |
| US8100872B2 (en) | 2002-10-23 | 2012-01-24 | Tyco Healthcare Group Lp | Medical dressing containing antimicrobial agent |
| US7762044B2 (en) | 2003-01-27 | 2010-07-27 | Medtronic Vascular, Inc. | Packaging for stent delivery systems |
| US20060142684A1 (en) | 2003-04-11 | 2006-06-29 | Shanbrom Technologies, Llc | Oxygen releasing material |
| SI1644024T1 (sl) * | 2003-06-06 | 2019-11-29 | Univ Texas | Protimikrobne raztopine za izpiranje |
| US7282186B2 (en) | 2003-06-20 | 2007-10-16 | Lake Jr Robert F | Decontamination device |
| US20040261196A1 (en) | 2003-06-27 | 2004-12-30 | The Procter & Gamble Company | Fabric care compositions for lipophilic fluid systems incorporating an antimicrobial agent |
| DE10331192A1 (de) | 2003-07-10 | 2005-02-03 | Paul Hartmann Ag | Hautfreundliches Einwegprodukt |
| US20050034731A1 (en) | 2003-08-13 | 2005-02-17 | Rousseau Robert A. | Surgical wound closure device |
| EP1670424A2 (en) * | 2003-09-13 | 2006-06-21 | Boots Healthcare International Limited | Skincare compositions comprising salicylic acid |
| JP4476593B2 (ja) | 2003-10-16 | 2010-06-09 | 日東電工株式会社 | 医療用粘着性抗菌シート |
| US20080057136A1 (en) | 2003-11-11 | 2008-03-06 | Veckis Industries Ltd. | Disinfecting Composition and Methods of Making and Using Same |
| GB2408207A (en) | 2003-11-24 | 2005-05-25 | Johnson & Johnson Medical Ltd | Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme |
| US20050129897A1 (en) | 2003-12-11 | 2005-06-16 | Kimberly-Clark Worldwide, Inc. | Disposable scrubbing product |
| KR101105081B1 (ko) | 2003-12-23 | 2012-01-16 | 헴콘 메디컬 테크놀로지스, 인크. | 키토산과 같은 친수성 중합체 스폰지 구조체로부터 형성된조직 드레싱 조립체, 시스템 및 방법 |
| US7204368B2 (en) | 2003-12-29 | 2007-04-17 | Cheaure Sarah F | Resealable package |
| JP2005350571A (ja) | 2004-06-10 | 2005-12-22 | Sekisui Chem Co Ltd | 熱可塑性樹脂発泡体シート及び熱可塑性樹脂発泡体シートの製造方法 |
| WO2005089341A2 (en) | 2004-03-16 | 2005-09-29 | Bull Brian S | Method and device for coronary artery bypass |
| US7478962B2 (en) | 2004-05-26 | 2009-01-20 | L'oreal | Device for packaging and application of a product |
| US20050281890A1 (en) | 2004-06-18 | 2005-12-22 | San Chandan K | Methods and compositions for wound healing |
| CN1711845A (zh) * | 2004-06-25 | 2005-12-28 | 殷生章 | 一种可杀灭非典肺炎冠状病毒的消毒剂 |
| CN101128173B (zh) | 2004-09-17 | 2012-06-20 | 大卫·M·狄克逊 | 伤口护理敷料及其使用方法 |
| US7506760B2 (en) | 2005-01-10 | 2009-03-24 | Grossman Victor A | Packaging and dispensers for adhesive backed elements |
| WO2006086271A2 (en) | 2005-02-07 | 2006-08-17 | Jacques Elfersy | Methods and compositions for biocidal treatments |
| WO2006089139A2 (en) | 2005-02-15 | 2006-08-24 | Lab39, Llc | Oral care cleaning compositions and methods |
| GB0525504D0 (en) | 2005-12-14 | 2006-01-25 | Bristol Myers Squibb Co | Antimicrobial composition |
| US20070179373A1 (en) | 2005-12-22 | 2007-08-02 | Provex Technologies, Llc. | Integrated patch and assay device with visual detection means |
| WO2007120616A2 (en) | 2006-04-11 | 2007-10-25 | Tyco Healthcare Group Lp | Wound dressings with anti-microbial and zinc-containing agents |
| US8162899B2 (en) | 2006-05-18 | 2012-04-24 | Hyprotek, Inc. | Intravascular line and port cleaning methods, methods of administering an agent intravascularly, methods of obtaining/testing blood, and devices for performing such methods |
| US7770726B2 (en) | 2006-06-08 | 2010-08-10 | Hollister Incorporated | Catheter product package and method of forming same |
| WO2008003779A1 (en) * | 2006-07-06 | 2008-01-10 | Centennial Ventures B.V. | Broad spectrum and skin friendly disinfecting composition |
| GB0614278D0 (en) | 2006-07-19 | 2006-08-30 | Insense Ltd | Hydrogen peroxide delivery system |
| US7780794B2 (en) | 2006-07-21 | 2010-08-24 | Ivera Medical Corporation | Medical implement cleaning device |
| US8403898B2 (en) | 2006-11-21 | 2013-03-26 | Mark R. Moore | Apparatus and method for deploying a surgical preparation |
| US8647326B2 (en) | 2007-01-16 | 2014-02-11 | Catheter Connections, Inc. | System for cleaning luer connectors |
| US8343536B2 (en) | 2007-01-25 | 2013-01-01 | Cook Biotech Incorporated | Biofilm-inhibiting medical products |
| US8336152B2 (en) | 2007-04-02 | 2012-12-25 | C. R. Bard, Inc. | Insert for a microbial scrubbing device |
| US8065773B2 (en) | 2007-04-02 | 2011-11-29 | Bard Access Systems, Inc. | Microbial scrub brush |
| US20090010998A1 (en) | 2007-07-03 | 2009-01-08 | Marchitto Kevin S | Drug-delivery patch comprising a dissolvable layer and uses thereof |
| US20090028750A1 (en) | 2007-07-23 | 2009-01-29 | Ryan Dana Wm | Cleaning and Disinfection Swabbing Device for Needle-Free Intravenous (IV) Connectors |
| US20090036541A1 (en) | 2007-08-02 | 2009-02-05 | Donald David Mardis | Applicator and chemical combination for better topical anesthesia |
| JP5666309B2 (ja) * | 2007-12-17 | 2015-02-12 | ノヴァファーム・リサーチ・(オーストラリア)・ピーティーワイ・リミテッド | 殺ウイルス用組成物 |
| US8388894B2 (en) | 2008-03-20 | 2013-03-05 | Psi Medical Catheter Care, Llc | Apparatus and method for sterilizing a tubular medical line port |
| WO2009136957A1 (en) | 2008-05-06 | 2009-11-12 | Ferlic Michael J | Universal sterilizing tool |
| US8777504B2 (en) | 2008-07-03 | 2014-07-15 | Retractable Technologies, Inc. | Cleaning tool |
| US20100030170A1 (en) | 2008-08-01 | 2010-02-04 | Keith Alan Keller | Absorptive Pad |
| US8486004B1 (en) | 2009-07-02 | 2013-07-16 | Centurion Medical Products Corporation | Dressing having integral antimicrobial |
| WO2011019132A1 (ko) | 2009-08-14 | 2011-02-17 | 중앙대학교 산학협력단 | 도전성 접착제, 이를 이용한 반도체의 실장방법 및 웨이퍼 레벨 패키지 |
| US20110184382A1 (en) | 2009-08-20 | 2011-07-28 | Cady Timothy B | Multi-purpose articles for sanitizing and capping luer access valves |
| US8778387B2 (en) | 2009-09-02 | 2014-07-15 | Hyprotek, Inc. | Antimicrobial medical dressings and protecting wounds and catheter sites |
| CN103108643B (zh) | 2010-01-22 | 2016-10-26 | 希普罗特克有限公司 | 包含过氧化物、醇和螯合剂的抗菌剂 |
| US8496625B2 (en) | 2010-05-26 | 2013-07-30 | Nxstage Medical, Inc. | Safe needle methods, apparatus, and systems |
| US20110314619A1 (en) | 2010-06-23 | 2011-12-29 | Medical Components, Inc. | Cleaner for Medical Device |
| SG10201604170QA (en) | 2011-11-28 | 2016-07-28 | Hyprotek Inc | Port and surface cleaning devices and techniques |
| CA2881361C (en) * | 2012-08-08 | 2022-03-08 | Board Of Regents, The University Of Texas System | Antimicrobial compositions comprising glyceryl nitrates |
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| WO2011091322A3 (en) | 2011-09-29 |
| US20130287860A1 (en) | 2013-10-31 |
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| US8846009B2 (en) | 2014-09-30 |
| BR112012018170B8 (pt) | 2021-05-25 |
| BR112012018170B1 (pt) | 2021-04-06 |
| US20130287861A1 (en) | 2013-10-31 |
| CN103108643A (zh) | 2013-05-15 |
| AU2011207398A1 (en) | 2012-07-26 |
| CN103108643B (zh) | 2016-10-26 |
| JP2013518056A (ja) | 2013-05-20 |
| US20120288571A1 (en) | 2012-11-15 |
| JP2016056186A (ja) | 2016-04-21 |
| BR112012018170A2 (pt) | 2018-11-06 |
| CA2786880C (en) | 2018-04-24 |
| US8846008B2 (en) | 2014-09-30 |
| US9253987B2 (en) | 2016-02-09 |
| AU2011207398B2 (en) | 2014-11-20 |
| WO2011091322A2 (en) | 2011-07-28 |
| JP6118918B2 (ja) | 2017-04-19 |
| KR20120117837A (ko) | 2012-10-24 |
| JP5866298B2 (ja) | 2016-02-17 |
| EP2525803A2 (en) | 2012-11-28 |
| RU2570387C2 (ru) | 2015-12-10 |
| MX2012008482A (es) | 2012-11-29 |
| EP2525803B1 (en) | 2017-04-26 |
| CA2786880A1 (en) | 2011-07-28 |
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