RU2006113431A - 2-Ethyl-6-methyl-3-hydroxypyridine n-acetylcysteinate possessing antioxidant, hypoglycemic, hypolipidemic, and anti-shock properties - Google Patents
2-Ethyl-6-methyl-3-hydroxypyridine n-acetylcysteinate possessing antioxidant, hypoglycemic, hypolipidemic, and anti-shock properties Download PDFInfo
- Publication number
- RU2006113431A RU2006113431A RU2006113431/15A RU2006113431A RU2006113431A RU 2006113431 A RU2006113431 A RU 2006113431A RU 2006113431/15 A RU2006113431/15 A RU 2006113431/15A RU 2006113431 A RU2006113431 A RU 2006113431A RU 2006113431 A RU2006113431 A RU 2006113431A
- Authority
- RU
- Russia
- Prior art keywords
- hydroxypyridine
- ethyl
- methyl
- acetylcysteinate
- hypolipidemic
- Prior art date
Links
- 230000000703 anti-shock Effects 0.000 title claims 2
- 239000003963 antioxidant agent Substances 0.000 title claims 2
- 230000003078 antioxidant effect Effects 0.000 title claims 2
- JPGDYIGSCHWQCC-UHFFFAOYSA-N emoxypine Chemical compound CCC1=NC(C)=CC=C1O JPGDYIGSCHWQCC-UHFFFAOYSA-N 0.000 title claims 2
- 230000000055 hyoplipidemic effect Effects 0.000 title claims 2
- 230000002218 hypoglycaemic effect Effects 0.000 title claims 2
- LUYMVIPYCQWZOO-VWMHFEHESA-N (2R)-2-acetamido-3-sulfanylpropanoic acid 2-ethyl-6-methylpyridin-3-ol Chemical compound C(C)C1=NC(=CC=C1O)C.C(C)(=O)N[C@@H](CS)C(=O)O LUYMVIPYCQWZOO-VWMHFEHESA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims 1
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 claims 1
- 238000009835 boiling Methods 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000029078 coronary artery disease Diseases 0.000 claims 1
- 238000004821 distillation Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000001953 recrystallisation Methods 0.000 claims 1
- 230000035939 shock Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 208000019553 vascular disease Diseases 0.000 claims 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006113431/04A RU2357955C2 (en) | 2006-04-21 | 2006-04-21 | Antioxidant, antihyperglycemic, hypolipidemic and antishock n-acetylcysteinate 2-ethyl-6-methyl-3-hydroxypyridine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006113431/04A RU2357955C2 (en) | 2006-04-21 | 2006-04-21 | Antioxidant, antihyperglycemic, hypolipidemic and antishock n-acetylcysteinate 2-ethyl-6-methyl-3-hydroxypyridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006113431A true RU2006113431A (en) | 2007-11-10 |
| RU2357955C2 RU2357955C2 (en) | 2009-06-10 |
Family
ID=38957904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006113431/04A RU2357955C2 (en) | 2006-04-21 | 2006-04-21 | Antioxidant, antihyperglycemic, hypolipidemic and antishock n-acetylcysteinate 2-ethyl-6-methyl-3-hydroxypyridine |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2357955C2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2365582C1 (en) * | 2008-07-03 | 2009-08-27 | Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" | Salt of 2-ethyl-6-methyl-3-hydroxypyridine with fumaric acid, possessing metabolic and cardioprotective activity, and method of its obtaining |
| RU2394816C1 (en) * | 2008-11-25 | 2010-07-20 | Виктор Владимирович Яснецов | Neurotropic agent with antioxidant, antihypoxic, neuroprotector, antiamnesic and anti-motion sickness activity and capable of enhancing cognitive functions |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2458714C1 (en) * | 2011-02-14 | 2012-08-20 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биохимической Физики Им. Н.М. Эмануэля Российской Академии Наук (Ибхф Ран) | Antioxidant, photoprotective and geroprotective agent |
| RU2637168C2 (en) * | 2015-03-12 | 2017-11-30 | Закрытое Акционерное Общество "Фармфирма "Сотекс" | Pharmaceutical composition in form of solute for intravenous and intramuscular injection and its production process |
| RU2664453C1 (en) * | 2017-11-24 | 2018-08-17 | федеральное государственное бюджетное образовательное учреждение высшего образования "Тверской государственный медицинский университет" Министерства здравоохранения Российской Федерации | Derivative of 3-hydroxypyridine with anxiolytic and nootropic effect |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2058145C1 (en) * | 1988-12-28 | 1996-04-20 | Центр по химии лекарственных средств | Agent showing antishock activity |
| RU2065299C1 (en) * | 1994-07-15 | 1996-08-20 | Акционерное общество закрытого типа "Олвик" | Nootropic and tranquilizing agent |
| RU2145855C1 (en) * | 1999-05-26 | 2000-02-27 | Смирнов Леонид Дмитриевич | Drug showing anxiolytic, antialcoholic and cerebroprotective effects |
| RU2210568C1 (en) * | 2001-12-14 | 2003-08-20 | Промоненков Виктор Кириллович | Method for preparing derivatives of 2-ethyl-6- -methyl-3- hydroxypyridine |
| RU2284993C2 (en) * | 2002-06-14 | 2006-10-10 | Леонид Дмитриевич Смирнов | 2-ethyl-6-methyl-3-oxypyrodine salts with organic carboxylic acids possessing anxiolytic, antidepressive, antihypoxic, anti-amnestic and anti-oxidative activity and method for their preparing |
-
2006
- 2006-04-21 RU RU2006113431/04A patent/RU2357955C2/en not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2365582C1 (en) * | 2008-07-03 | 2009-08-27 | Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" | Salt of 2-ethyl-6-methyl-3-hydroxypyridine with fumaric acid, possessing metabolic and cardioprotective activity, and method of its obtaining |
| RU2394816C1 (en) * | 2008-11-25 | 2010-07-20 | Виктор Владимирович Яснецов | Neurotropic agent with antioxidant, antihypoxic, neuroprotector, antiamnesic and anti-motion sickness activity and capable of enhancing cognitive functions |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2357955C2 (en) | 2009-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20160422 |