RU2006101686A - Композиции для местного применения, восстанавливающие структуру ногтей - Google Patents
Композиции для местного применения, восстанавливающие структуру ногтей Download PDFInfo
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- RU2006101686A RU2006101686A RU2006101686/15A RU2006101686A RU2006101686A RU 2006101686 A RU2006101686 A RU 2006101686A RU 2006101686/15 A RU2006101686/15 A RU 2006101686/15A RU 2006101686 A RU2006101686 A RU 2006101686A RU 2006101686 A RU2006101686 A RU 2006101686A
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- 239000000203 mixture Substances 0.000 title claims abstract 14
- 244000085625 Equisetum Species 0.000 claims abstract 3
- 229920001661 Chitosan Polymers 0.000 claims 8
- 241000196324 Embryophyta Species 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 3
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 2
- 241000195950 Equisetum arvense Species 0.000 claims 2
- 239000005768 Equisetum arvense L. Substances 0.000 claims 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 125000004181 carboxyalkyl group Chemical group 0.000 claims 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 239000011593 sulfur Substances 0.000 claims 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 241000195955 Equisetum hyemale Species 0.000 claims 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- 239000004166 Lanolin Substances 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 229940054190 hydroxypropyl chitosan Drugs 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 229940039717 lanolin Drugs 0.000 claims 1
- 235000019388 lanolin Nutrition 0.000 claims 1
- 239000004611 light stabiliser Substances 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 229960005015 local anesthetics Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940016409 methylsulfonylmethane Drugs 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 239000003961 penetration enhancing agent Substances 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
- 150000004760 silicates Chemical class 0.000 claims 1
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 claims 1
- 229960003080 taurine Drugs 0.000 claims 1
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical compound OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 claims 1
- 229950001139 timonacic Drugs 0.000 claims 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9741—Pteridophyta [ferns]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dispersion Chemistry (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (23)
1. Применение композиции, содержащей
a) по крайней мере один экстракт травянистого растения из рода Equisetum,
b) по крайней мере одно средство для образования пленки для изготовления препарата для местного использования для лечения онихошизии.
2. Применение по п.1, где композиция дополнительно содержит c) по крайней мере один физиологически приемлемый носитель.
3. Применение по п.1, где композиция дополнительно содержит d) по крайней мере один донор серы.
4. Применение по п.1, где компонент a) выбирают из Equisetum arvense в виде растения или части растения, сока, сухого экстракта, спиртового экстракта, водно-спиртового экстракта или гликолевого экстракта, или Equisetum hiemale в виде растения или части растения, сока, сухого экстракта, спиртового экстракта, водно-спиртового экстракта или гликолевого экстракта.
5. Применение по п.1, где компонент a) представляет собой гликолевый экстракт Equisetum arvense.
6. Применение по п.1, где компонент b) представляет собой водорастворимое средство для образования пленки.
7. Применение по п.6, где указанное водорастворимое средство для образования пленки представляет собой производное хитозана.
8. Применение по п.7, где указанное производное хитозана выбирают из гидроксиалкилхитозанов и/или карбоксиалкилхитозанов.
9. Применение по п.8, где указанные гидроксиалкилхитозаны выбирают из хитозанов, замещенных C1-6-алкильными группами, с гидроксигруппами в количестве от 1 до 3, предпочтительно гидроксипропилхитозан.
10. Применение по п.8, где указанные карбоксиалкилхитозаны выбирают из хитозанов, замещенных C1-6-алкильными группами, с карбоксигруппами в количестве от 1 до 3, предпочтительно карбоксиметилхитозан.
11. Применение по любому из предшествующих пунктов, где компонент c) представляет собой воду или смесь воды, по крайней мере, с одним вспомогательным растворителем.
12. Применение по п.11, где указанный вспомогательный растворитель представляет собой спирт.
13. Применение по п.12, где указанный спирт представляет собой спирт с разветвленной или линейной структурой, с гидроксигруппами в количестве от 1 до 3 и с количеством атомов углерода от 2 до 6, предпочтительно этанол, 1-пропанол и/или изопропанол.
14. Применение по п.1, где компонент d) выбирают из сульфатированных аминокислот и их производных, l-метионина, l-цистеина, l-цистина, таурина, 4-тиазолидинкарбоновой кислоты и/или метилсульфонилметана.
15. Применение по п.1, где композиция дополнительно содержит средства, способствующие проникновению внутрь, замедлители осаждения, хелатообразующие средства, антиоксиданты, силикаты, ароматизаторы, увлажнители, производные ланолина, светостабилизаторы и/или противобактериальные средства.
16. Применение по п.1, где композиция дополнительно содержит добавочные активные средства, выбранные из противогрибковых средств, антибиотиков, противовоспалительных средств, антисептических средств и/или обезболивающих средств местного действия.
17. Применение по п.1, где компонент a) присутствует в количестве от 0,1 до 15 мас.%, предпочтительно от 0,3 до 15 мас.%, более предпочтительно от 0,5 до 10 мас.% от общей массы композиции.
18. Применение по п.1, где компонент b) присутствует в количестве от 0,1 до 10 мас.%, предпочтительно от 0,3 до 8 мас.%, более предпочтительно от 0,5 до 5 мас.% от общей массы композиции.
19. Применение по п.2, где компонент c) присутствует в количестве от 40 до 99,8 мас.%, предпочтительно от 60 до 99 мас.%, более предпочтительно от 80 до 95 мас.% от общей массы композиции.
20. Применение по п.19, где содержание воды в компоненте c) составляет от 15 до 70 мас.%, предпочтительно от 30 до 65 мас.% от массы компонента c).
21. Применение по п.3, где компонент d) присутствует в количестве от 0,1 до 20 мас.%, предпочтительно от 0,2 до 10 мас.% от общей массы композиции.
22. Применение по п.1, где композиция, по существу, включает в себя
c) по крайней мере один экстракт травянистого растения из рода Equisetum,
d) по крайней мере одно средство для образования пленки,
e) по крайней мере один физиологически приемлемый носитель,
f) по крайней мере один донор серы.
23.Применение композиции по любому из предшествующих пунктов в качестве препарата для местного применения для ногтей.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20030076934 EP1491202A1 (en) | 2003-06-23 | 2003-06-23 | Nail restructuring compositions for topical application |
| EP03076934.3 | 2003-06-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006101686A true RU2006101686A (ru) | 2006-07-27 |
| RU2358748C2 RU2358748C2 (ru) | 2009-06-20 |
Family
ID=33395922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006101686/15A RU2358748C2 (ru) | 2003-06-23 | 2004-06-15 | Композиции для местного применения, восстанавливающие структуру ногтей |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20060134039A1 (ru) |
| EP (2) | EP1491202A1 (ru) |
| JP (1) | JP5037121B2 (ru) |
| KR (2) | KR101140272B1 (ru) |
| CN (1) | CN100430044C (ru) |
| AT (1) | ATE369870T1 (ru) |
| BR (1) | BRPI0411705B1 (ru) |
| CA (1) | CA2528313C (ru) |
| CY (1) | CY1106949T1 (ru) |
| DE (1) | DE602004008272T2 (ru) |
| DK (1) | DK1635852T3 (ru) |
| ES (1) | ES2289527T3 (ru) |
| HR (1) | HRP20070431T3 (ru) |
| IL (1) | IL172180A (ru) |
| ME (2) | MEP23108A (ru) |
| MX (1) | MXPA05013820A (ru) |
| PT (1) | PT1635852E (ru) |
| RS (1) | RS51879B (ru) |
| RU (1) | RU2358748C2 (ru) |
| SI (1) | SI1635852T1 (ru) |
| WO (1) | WO2004112814A1 (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060127342A1 (en) * | 2004-12-09 | 2006-06-15 | Georgia Levis | Taurine-based compositions, therapeutic methods, and assays |
| EP1958638A1 (en) | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans to increase nail growth rate |
| EP1958639A1 (en) * | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans for the treatment of nail inflammatory diseases |
| US10201490B2 (en) | 2007-02-14 | 2019-02-12 | Polichem Sa | Use of chitosans for the treatment of nail inflammatory diseases |
| EP1958613A1 (en) * | 2007-02-15 | 2008-08-20 | Polichem S.A. | Dermal film-forming liquid formulations for drug release to skin |
| IT1390844B1 (it) * | 2008-07-29 | 2011-10-19 | Trasdeco Int S R L | Composizione cosmetica per unghie e relativo metodo di applicazione |
| EP2153836A1 (en) * | 2008-08-04 | 2010-02-17 | Polichem S.A. | Film-forming liquid formulations for drug release to hair and scalp |
| EP2116237A1 (en) | 2008-08-05 | 2009-11-11 | Polichem SA | Compositions for treating rosacea comprising chitosan and a dicarboxylic acid |
| TR201103770A1 (tr) * | 2011-04-19 | 2012-11-21 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Nimesulid ve metilsülfonilmetanin topikalfarmasötik bileşimleri. |
| US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| EP2845597A1 (en) * | 2013-09-10 | 2015-03-11 | Polichem S.A. | Hydroxypropyl chitosan for the treatment of onychomycosis |
| EP2952208A1 (en) * | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Hydroalcoholic system for nail treatment |
| JP6570316B2 (ja) * | 2015-05-25 | 2019-09-04 | ロート製薬株式会社 | 爪用組成物 |
| KR102485403B1 (ko) | 2020-08-31 | 2023-01-17 | 주식회사 비앤에이치웍스 | 손발톱 강화용 조성물 |
| KR102597564B1 (ko) * | 2023-03-03 | 2023-11-03 | 장병모 | 조갑 및 피부 백선의 예방 또는 치료용 약학적 조성물 |
| CN120585945A (zh) * | 2024-01-11 | 2025-09-05 | 生物疗法、健康生理系统共同股份公司 | 用于治疗骨质脆弱的天然基质混合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| FR2610523B1 (fr) * | 1987-02-06 | 1991-04-26 | Synthelabo | Extrait dose de silicium biogene, sa preparation et son application en therapeutique |
| US5133958A (en) * | 1989-04-20 | 1992-07-28 | Erwin Stuckler | Agent for nail, skin and hair care |
| US5478579A (en) * | 1991-02-06 | 1995-12-26 | Biodyn Medical Research, Inc. | Method for treatment of osteoporosis |
| FR2681782B1 (fr) * | 1991-09-26 | 1993-12-17 | Oreal | Composition pour le traitement des ongles contenant un aminoacide soufre. |
| ATE171070T1 (de) * | 1993-05-02 | 1998-10-15 | Helmut Koeniger | Neue verwendung von equisetum |
| FR2718637A1 (fr) * | 1994-04-15 | 1995-10-20 | Oreal | Composition cosmétique à appliquer sur l'ongle. |
| RU2083224C1 (ru) | 1994-09-30 | 1997-07-10 | Сергей Федорович Подчайнов | Противогрибковое средство для стоп |
| US6027402A (en) * | 1996-11-18 | 2000-02-22 | Sunfiles, Llc | Cosmetic file/buffer with microencapsulated treatment substances |
| AU7174998A (en) * | 1997-05-01 | 1998-11-24 | Medlogic Global Corporation | Compositions for cosmetic applications |
| JPH11193217A (ja) * | 1997-12-26 | 1999-07-21 | Kao Corp | ネイルトリートメント組成物 |
| US6919076B1 (en) * | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| DE19826943C2 (de) | 1998-06-17 | 2001-12-06 | Daimler Chrysler Ag | Tunnelverkleidung für ein Kraftfahrzeug |
| AU4984899A (en) | 1998-07-14 | 2000-02-07 | Adams Food Ltd. | Nutritionally active composition for hardening fingernails |
| US6589571B2 (en) * | 1998-08-13 | 2003-07-08 | Helmut Koniger | Method for combating summer eczema and malanders |
| RU2140264C1 (ru) * | 1998-09-24 | 1999-10-27 | Тихоокеанский институт биоорганической химии Дальневосточного отделения РАН | Средство для наружного применения "полимед" |
| KR20010026947A (ko) * | 1999-09-09 | 2001-04-06 | 이충삼 | 건강보조식품 제조방법 |
| US6596266B2 (en) * | 2000-02-18 | 2003-07-22 | Natural Science, Inc. | Compositions containing minoxidil and saw palmetto for treating baldness |
| DE10035991A1 (de) * | 2000-07-24 | 2002-02-14 | Polichem Sa | Nagellackzusammensetzung |
| RU2206315C2 (ru) * | 2000-08-17 | 2003-06-20 | Черных Сергей Львович | Лечебно-косметический крем |
| JP2002179521A (ja) * | 2000-12-13 | 2002-06-26 | Ichimaru Pharcos Co Ltd | 植物又は動物抽出物含有化粧料組成物 |
| EP1275371A1 (en) * | 2001-07-13 | 2003-01-15 | Johnson and Johnson GmbH | Dry products comprising a sheet and two phases |
| FR2829696B1 (fr) * | 2001-09-17 | 2004-02-27 | Oreal | Utilisation de l'acide pantetheine sulfonique et/ou de ses sels en tant qu'agent anti-radicalaire |
| US6844303B2 (en) * | 2001-12-14 | 2005-01-18 | Rainer Lange | Cleaning compositions and their use in feminine hygiene wipes |
| CA2383296A1 (fr) | 2002-05-10 | 2003-11-10 | Ginette Godbout | Composition pour l'amelioration de la sante et de la structure des ongles, methode d'utilisation |
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2003
- 2003-06-23 EP EP20030076934 patent/EP1491202A1/en not_active Withdrawn
-
2004
- 2004-06-15 DK DK04740007T patent/DK1635852T3/da active
- 2004-06-15 US US10/559,794 patent/US20060134039A1/en not_active Abandoned
- 2004-06-15 WO PCT/EP2004/006549 patent/WO2004112814A1/en not_active Ceased
- 2004-06-15 JP JP2006515978A patent/JP5037121B2/ja not_active Expired - Lifetime
- 2004-06-15 PT PT04740007T patent/PT1635852E/pt unknown
- 2004-06-15 AT AT04740007T patent/ATE369870T1/de active
- 2004-06-15 KR KR1020057023566A patent/KR101140272B1/ko not_active Expired - Lifetime
- 2004-06-15 ME MEP-231/08A patent/MEP23108A/xx unknown
- 2004-06-15 ME MEP-2008-231A patent/ME00190B/me unknown
- 2004-06-15 EP EP04740007A patent/EP1635852B1/en not_active Expired - Lifetime
- 2004-06-15 RU RU2006101686/15A patent/RU2358748C2/ru active
- 2004-06-15 MX MXPA05013820A patent/MXPA05013820A/es active IP Right Grant
- 2004-06-15 HR HR20070431T patent/HRP20070431T3/xx unknown
- 2004-06-15 DE DE602004008272T patent/DE602004008272T2/de not_active Expired - Lifetime
- 2004-06-15 CA CA2528313A patent/CA2528313C/en not_active Expired - Lifetime
- 2004-06-15 RS YU20050925A patent/RS51879B/sr unknown
- 2004-06-15 ES ES04740007T patent/ES2289527T3/es not_active Expired - Lifetime
- 2004-06-15 BR BRPI0411705-0A patent/BRPI0411705B1/pt not_active IP Right Cessation
- 2004-06-15 SI SI200430460T patent/SI1635852T1/sl unknown
- 2004-06-15 CN CNB2004800177364A patent/CN100430044C/zh not_active Expired - Lifetime
- 2004-06-15 KR KR1020127005145A patent/KR20120027554A/ko not_active Ceased
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2005
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2007
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