RU2006142622A - METHOD FOR TREATING ACUTE MYOCARDIAL INFARCTION - Google Patents
METHOD FOR TREATING ACUTE MYOCARDIAL INFARCTION Download PDFInfo
- Publication number
- RU2006142622A RU2006142622A RU2006142622/14A RU2006142622A RU2006142622A RU 2006142622 A RU2006142622 A RU 2006142622A RU 2006142622/14 A RU2006142622/14 A RU 2006142622/14A RU 2006142622 A RU2006142622 A RU 2006142622A RU 2006142622 A RU2006142622 A RU 2006142622A
- Authority
- RU
- Russia
- Prior art keywords
- myocardial infarction
- acute myocardial
- solution
- blood flow
- restoration
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 11
- 206010000891 acute myocardial infarction Diseases 0.000 title claims abstract 7
- 239000003814 drug Substances 0.000 claims abstract 8
- 206010063837 Reperfusion injury Diseases 0.000 claims abstract 6
- 229940079593 drug Drugs 0.000 claims abstract 6
- 210000004165 myocardium Anatomy 0.000 claims abstract 6
- 230000017531 blood circulation Effects 0.000 claims abstract 4
- 210000004351 coronary vessel Anatomy 0.000 claims abstract 4
- IKMNOGHPKNFPTK-UHFFFAOYSA-N 2-ethyl-6-methylpyridin-1-ium-3-ol;4-hydroxy-4-oxobutanoate Chemical compound OC(=O)CCC(O)=O.CCC1=NC(C)=CC=C1O IKMNOGHPKNFPTK-UHFFFAOYSA-N 0.000 claims abstract 2
- 206010061216 Infarction Diseases 0.000 claims abstract 2
- 230000007574 infarction Effects 0.000 claims abstract 2
- 208000010125 myocardial infarction Diseases 0.000 claims abstract 2
- 238000002203 pretreatment Methods 0.000 claims abstract 2
- 230000002265 prevention Effects 0.000 claims abstract 2
- 238000010561 standard procedure Methods 0.000 claims abstract 2
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1. Способ лечения острого инфаркта миокарда, включающий введение лекарственного средства, позволяющего уменьшить реперфузионное повреждение миокарда до момента восстановления антеградного кровотока, дистальнее окклюзии коронарной артерии, по каналу баллона долгой замены, с помощью которого выполняется стандартная процедура предилятации инфаркт-ответственной коронарной артерии, в течение 1-10 мин.2. Способ по п.1, в котором в качестве лекарственных средств используют препараты, разрешенные к медицинскому применению при остром инфаркте миокарда и/или доказавшие свою эффективность на экспериментальных моделях профилактики реперфузионного повреждения сердечной мышцы.3. Способ по п.1 или 2, в котором в качестве лекарственного средства, доказавшего свою эффективность в профилактике реперфузионного повреждения миокарда при восстановлении коронарного кровотока у больных острым инфарктом миокарда, используют раствор 2-этил-6-метил-3-оксипиридинсукцината.4. Способ по п.3, в котором указанный раствор вводят в инфарцированную область в дозе 50-800 мг.5. Способ по п.1 или 2, в котором указанный раствор вводят со скоростью 0,1-4 мл/с.1. A method of treating acute myocardial infarction, including the introduction of a drug that allows to reduce reperfusion damage to the myocardium until the restoration of antegrade blood flow, distal to occlusion of the coronary artery, through the long replacement balloon channel, using which the standard procedure for the pre-treatment of heart attack-responsible coronary artery is performed, during 1-10 min. 2. The method according to claim 1, wherein drugs that are approved for medical use in acute myocardial infarction and / or have proven effective in experimental models for the prevention of reperfusion injury to the heart muscle are used as medicines. The method according to claim 1 or 2, in which a solution of 2-ethyl-6-methyl-3-hydroxypyridine succinate is used as a medicine that has proven effective in preventing reperfusion damage to the myocardium during restoration of coronary blood flow in patients with acute myocardial infarction. The method according to claim 3, wherein said solution is introduced into the infarction region at a dose of 50-800 mg. The method according to claim 1 or 2, wherein said solution is administered at a rate of 0.1-4 ml / s.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006142622/14A RU2343921C2 (en) | 2006-12-01 | 2006-12-01 | Method of treatment of acute myocardial infarction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006142622/14A RU2343921C2 (en) | 2006-12-01 | 2006-12-01 | Method of treatment of acute myocardial infarction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006142622A true RU2006142622A (en) | 2008-06-20 |
| RU2343921C2 RU2343921C2 (en) | 2009-01-20 |
Family
ID=40376182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006142622/14A RU2343921C2 (en) | 2006-12-01 | 2006-12-01 | Method of treatment of acute myocardial infarction |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2343921C2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2395850C2 (en) * | 2008-06-23 | 2010-07-27 | Петр Алексеевич Сарапульцев | Method of treating experimental myocardial infarction in rats |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2526185C1 (en) * | 2013-07-30 | 2014-08-20 | Федеральное государственное бюджетное учреждение "Научный центр экспертизы средств медицинского применения" Министерства здравоохранения Российской Федерации (ФГБУ "НЦЭСМП" Минздрава России) | Method of increasing oxygen tension in blood of patients with chronic heart failure |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050124971A1 (en) * | 2003-07-21 | 2005-06-09 | Duke University | Methods and devices for catheter-based intracoronary myocardial delivery of cellular, genetic or biological materials |
| RU2267323C1 (en) * | 2004-09-09 | 2006-01-10 | Давид Георгиевич Иоселиани | Method for treating acute myocardial infarction cases |
-
2006
- 2006-12-01 RU RU2006142622/14A patent/RU2343921C2/en not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2395850C2 (en) * | 2008-06-23 | 2010-07-27 | Петр Алексеевич Сарапульцев | Method of treating experimental myocardial infarction in rats |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2343921C2 (en) | 2009-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2010004508A (en) | Delivery of active agents. | |
| BRPI0414455A (en) | Methods for Using Regenerative Cells to Treat Peripheral Vascular Disease and Related Disorders | |
| AR071810A1 (en) | METHOD OF TREATMENT OF DISNEA ASSOCIATED WITH ACUTE CARDIAC INSUFFICIENCY. RELAXIN H2. USE. | |
| AR049985A1 (en) | COMBINATION TREATMENT FOR NON-HEMATOLOGICAL MALIGNAL DISEASES | |
| EA200970360A1 (en) | OMEGA-3 FATTY ACIDS AND MEANS FOR THE TREATMENT OF DYSLIPIDEMIA TO REDUCE APRO-V LEVELS | |
| AR082803A1 (en) | METHODS AND FORMULATIONS FOR THE TREATMENT OF THROMBOSIS WITH BETRIXABAN AND A GLICOPROTEIN P INHIBITOR | |
| RU2015134581A (en) | NITROXIL DONORS WITH IMPROVED THERAPEUTIC INDEX | |
| RU2107496C1 (en) | Method to treat diabetic angiopathy | |
| JP2018526460A5 (en) | ||
| EA202090564A1 (en) | METHODS FOR STRENGTHENING AND / OR STABILIZING THE CARDIAC FUNCTION IN PATIENTS WITH FABRIC DISEASE | |
| Lasemi et al. | Articaine (4%) with epinephrine (1: 100,000 or 1: 200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia | |
| MX2015014939A (en) | Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias. | |
| RU2008148334A (en) | WATER EXTRACT OF TOBACCO LEAVES AND ITS APPLICATION IN TREATING DEPENDENCE | |
| RU2006142622A (en) | METHOD FOR TREATING ACUTE MYOCARDIAL INFARCTION | |
| JP2016510040A5 (en) | ||
| WO2001080895A3 (en) | Methods and compositions for the treatment of cardiac indications | |
| CA2516458A1 (en) | Use of kahalalide compounds for the manufacture of a medicament for the treatment of psoriasis | |
| WO2006016351A3 (en) | Drug delivery in the coronary sinus | |
| RU2014154396A (en) | LIQUID MEDICINAL CONTAINING CARBON OXIDE DISSOLVED IN IT AND THE THERAPEUTIC METHOD OF USE | |
| HRP20200897T1 (en) | PARENTERAL FORMULATION OF ESMOLOL | |
| CN202198976U (en) | A multifunctional intracranial tumor interstitial radiochemotherapy pump | |
| RU2380098C2 (en) | Method for prevention of postocclusive syndrome in x-ray endovascular treatment of myomas of body of uterus | |
| RU2077892C1 (en) | Method for treating recidivating pulmonary edema | |
| RU2007136505A (en) | METHOD FOR TREATING ACUTE LIMB ISCHEMIA | |
| Guru | Importance of transoesophageal echocardiography in preventing complications due to intraoperative dislodgement of left atrial thrombus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20191202 |