RU2006140999A - PAS-2 RECOMBINANT PLASMID DNA ENCODING A HUMAN ASPART PROINSULINE PROLINE POLYPEPTIDE AND ESCHERICHIA COLI BAS2 STRAIN OF BACTERIA - PRODUCER OF ASPART RECOMBINANT PROINSULIN - Google Patents
PAS-2 RECOMBINANT PLASMID DNA ENCODING A HUMAN ASPART PROINSULINE PROLINE POLYPEPTIDE AND ESCHERICHIA COLI BAS2 STRAIN OF BACTERIA - PRODUCER OF ASPART RECOMBINANT PROINSULIN Download PDFInfo
- Publication number
- RU2006140999A RU2006140999A RU2006140999/13A RU2006140999A RU2006140999A RU 2006140999 A RU2006140999 A RU 2006140999A RU 2006140999/13 A RU2006140999/13 A RU 2006140999/13A RU 2006140999 A RU2006140999 A RU 2006140999A RU 2006140999 A RU2006140999 A RU 2006140999A
- Authority
- RU
- Russia
- Prior art keywords
- aspart
- proinsulin
- human
- recombinant
- pas
- Prior art date
Links
- 108010076181 Proinsulin Proteins 0.000 title claims 5
- 229960004717 insulin aspart Drugs 0.000 title claims 5
- VOMXSOIBEJBQNF-UTTRGDHVSA-N novorapid Chemical compound C([C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(O)=O)C1=CC=C(O)C=C1.C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 VOMXSOIBEJBQNF-UTTRGDHVSA-N 0.000 title claims 5
- 241000282414 Homo sapiens Species 0.000 title claims 4
- 239000013612 plasmid Substances 0.000 title claims 4
- 241000588724 Escherichia coli Species 0.000 title claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 title claims 3
- 101100325773 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) BAS2 gene Proteins 0.000 title claims 2
- 101100083256 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) PHO2 gene Proteins 0.000 title claims 2
- 241000894006 Bacteria Species 0.000 title 1
- 102100035716 Glycophorin-A Human genes 0.000 title 1
- 101001074244 Homo sapiens Glycophorin-A Proteins 0.000 title 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 title 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 101100353517 Caenorhabditis elegans pas-2 gene Proteins 0.000 claims 2
- YOBGUCWZPXJHTN-BQBZGAKWSA-N Gly-Ser-Arg Chemical compound NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(O)=O)CCCN=C(N)N YOBGUCWZPXJHTN-BQBZGAKWSA-N 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000204 Dipeptidase 1 Proteins 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 108010088160 Staphylococcal Protein A Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
- 210000003705 ribosome Anatomy 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
Landscapes
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006140999/13A RU2337964C2 (en) | 2006-11-21 | 2006-11-21 | RECOMBINANT PLASMID DNA pAS-2 ENCODING HUMAN BEING PROINSULIN POLYPEPTIDE Aspart AND STRAIN OF BACTERIA Escherichia coli BAS2-RECOMBINANT PROINSULIN Aspart PRODUCER |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006140999/13A RU2337964C2 (en) | 2006-11-21 | 2006-11-21 | RECOMBINANT PLASMID DNA pAS-2 ENCODING HUMAN BEING PROINSULIN POLYPEPTIDE Aspart AND STRAIN OF BACTERIA Escherichia coli BAS2-RECOMBINANT PROINSULIN Aspart PRODUCER |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006140999A true RU2006140999A (en) | 2008-05-27 |
| RU2337964C2 RU2337964C2 (en) | 2008-11-10 |
Family
ID=39586244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006140999/13A RU2337964C2 (en) | 2006-11-21 | 2006-11-21 | RECOMBINANT PLASMID DNA pAS-2 ENCODING HUMAN BEING PROINSULIN POLYPEPTIDE Aspart AND STRAIN OF BACTERIA Escherichia coli BAS2-RECOMBINANT PROINSULIN Aspart PRODUCER |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2337964C2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2514578C1 (en) * | 2013-04-29 | 2014-04-27 | Общество с ограниченной ответственностью "БиоКлонТек" | RECOMBINANT PLASMID DNA pHIASP03, ENCODING HYBRID PROTEIN WITH HUMAN PROINSULIN Aspart, CELL Escherichia coli TRANSFORMED BY RECOMBINANT PLASMID DNA pHIAsp03, AND STRAIN OF BACTERIA Escherichia coli JM109/pHIAsp03 - PRODUCER OF HYBRID PROTEIN WITH HUMAN PROINSULIN Aspart |
| RU2729353C1 (en) * | 2019-05-24 | 2020-08-06 | Закрытое акционерное общество "ФАРМ-ХОЛДИНГ" | Recombinant plasmid dna pf646 coding hybrid polypeptide containing proinsulin aspart, and strain of bacteria escherichia coli - producer of hybrid polypeptide containing proinsulin aspart |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU607209B2 (en) * | 1987-04-23 | 1991-02-28 | Monsanto Technology Llc | Secretion of insulin-like growth factor-i in e. coli |
| RU2144957C1 (en) * | 1999-02-26 | 2000-01-27 | Институт биоорганической химии им.М.М.Шемякина и Ю.А.Овчинникова РАН | Recombinant plasmid dna ppins07 encoding fused polypeptide containing human proinsulin and strain of bacterium escherichia coli - producer of fused polypeptide containing human proinsulin |
| RU2235776C1 (en) * | 2003-03-17 | 2004-09-10 | Институт биоорганической химии им. академиков М.М.Шемякина и Ю.А.Овчинникова РАН | Recombinant plasmid dna plp-3-1 encoding human polypeptide of proinsulin lyspro and strain of bacterium escherichia coli plp-3-1/tg-1 as producer of recombinant proinsulin lyspro |
-
2006
- 2006-11-21 RU RU2006140999/13A patent/RU2337964C2/en active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2337964C2 (en) | 2008-11-10 |
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