RU2004125608A - Нуклеиновая кислота, кодирующая рецептор, связанный с g-белком, и ее применение - Google Patents

Нуклеиновая кислота, кодирующая рецептор, связанный с g-белком, и ее применение Download PDF

Info

Publication number: RU2004125608A
Authority: RU; Russia
Prior art keywords: gave6; promoter; nucleic acid; agonist; acid molecule
Prior art date: 2002-01-23

Application number

RU2004125608/15A

Other languages

English (en)

Russian (ru)

Inventor

Хайфенг ЭЙШИНГДРЕЛО (US)

Хайфенг ЭЙШИНГДРЕЛО

Дзидонг КАИ (US)

Дзидонг КАИ

Энтони САНДРАСАГРА (US)

Энтони Сандрасагра

Original Assignee

Авентис Фармасьютикалз Инк. (Us)

Авентис Фармасьютикалз Инк.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-23

Filing date

2003-01-21

Publication date

2005-04-20

2002-05-09 Priority claimed from GBGB0210597.1A external-priority patent/GB0210597D0/en

2003-01-21 Application filed by Авентис Фармасьютикалз Инк. (Us), Авентис Фармасьютикалз Инк. filed Critical Авентис Фармасьютикалз Инк. (Us)

2005-04-20 Publication of RU2004125608A publication Critical patent/RU2004125608A/ru

Links

108020004707 nucleic acids Proteins 0.000 title claims 12
102000039446 nucleic acids Human genes 0.000 title claims 12
150000007523 nucleic acids Chemical class 0.000 title claims 12
210000004027 cell Anatomy 0.000 claims 10
229920001184 polypeptide Polymers 0.000 claims 10
102000004196 processed proteins & peptides Human genes 0.000 claims 10
108090000765 processed proteins & peptides Proteins 0.000 claims 10
239000000556 agonist Substances 0.000 claims 9
229940125425 inverse agonist Drugs 0.000 claims 7
239000005557 antagonist Substances 0.000 claims 6
239000013604 expression vector Substances 0.000 claims 6
230000000694 effects Effects 0.000 claims 5
238000000034 method Methods 0.000 claims 5
125000003275 alpha amino acid group Chemical group 0.000 claims 4
230000001105 regulatory effect Effects 0.000 claims 4
230000007781 signaling event Effects 0.000 claims 4
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
102000004190 Enzymes Human genes 0.000 claims 3
108090000790 Enzymes Proteins 0.000 claims 3
230000007423 decrease Effects 0.000 claims 3
230000002285 radioactive effect Effects 0.000 claims 3
239000000126 substance Substances 0.000 claims 3
240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
241000700647 Variola virus Species 0.000 claims 2
239000006274 endogenous ligand Substances 0.000 claims 2
238000009396 hybridization Methods 0.000 claims 2
230000011664 signaling Effects 0.000 claims 2
230000001225 therapeutic effect Effects 0.000 claims 2
241000701161 unidentified adenovirus Species 0.000 claims 2
GZCWLCBFPRFLKL-UHFFFAOYSA-N 1-prop-2-ynoxypropan-2-ol Chemical compound CC(O)COCC#C GZCWLCBFPRFLKL-UHFFFAOYSA-N 0.000 claims 1
OSJPPGNTCRNQQC-UWTATZPHSA-N 3-phospho-D-glyceric acid Chemical compound OC(=O)[C@H](O)COP(O)(O)=O OSJPPGNTCRNQQC-UWTATZPHSA-N 0.000 claims 1
102000013563 Acid Phosphatase Human genes 0.000 claims 1
108010051457 Acid Phosphatase Proteins 0.000 claims 1
241000193830 Bacillus <bacterium> Species 0.000 claims 1
101100348617 Candida albicans (strain SC5314 / ATCC MYA-2876) NIK1 gene Proteins 0.000 claims 1
241000702374 Enterobacteria phage fd Species 0.000 claims 1
101710091045 Envelope protein Proteins 0.000 claims 1
241000588724 Escherichia coli Species 0.000 claims 1
241000701959 Escherichia virus Lambda Species 0.000 claims 1
108700039691 Genetic Promoter Regions Proteins 0.000 claims 1
108091028043 Nucleic acid sequence Proteins 0.000 claims 1
108091000080 Phosphotransferase Proteins 0.000 claims 1
101710188315 Protein X Proteins 0.000 claims 1
101100007329 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) COS1 gene Proteins 0.000 claims 1
101100221606 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) COS7 gene Proteins 0.000 claims 1
102100021696 Syncytin-1 Human genes 0.000 claims 1
230000000295 complement effect Effects 0.000 claims 1
201000010099 disease Diseases 0.000 claims 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
210000003527 eukaryotic cell Anatomy 0.000 claims 1
230000002163 immunogen Effects 0.000 claims 1
230000001939 inductive effect Effects 0.000 claims 1
102000020233 phosphotransferase Human genes 0.000 claims 1
210000001236 prokaryotic cell Anatomy 0.000 claims 1
239000000523 sample Substances 0.000 claims 1
238000002560 therapeutic procedure Methods 0.000 claims 1
238000001890 transfection Methods 0.000 claims 1
230000009466 transformation Effects 0.000 claims 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Biochemistry (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

RU2004125608/15A 2002-01-23 2003-01-21 Нуклеиновая кислота, кодирующая рецептор, связанный с g-белком, и ее применение RU2004125608A (ru)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US35100602P	2002-01-23	2002-01-23
US60/351,006		2002-01-23
GB0210597.1		2002-05-09
GBGB0210597.1A GB0210597D0 (en)	2002-01-23	2002-05-09	A nucleic acid encoding a G-protein-coupled receptor,and uses thereof

Publications (1)

Publication Number	Publication Date
RU2004125608A true RU2004125608A (ru)	2005-04-20

Family

ID=27614811

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RU2004125608/15A RU2004125608A (ru)	2002-01-23	2003-01-21	Нуклеиновая кислота, кодирующая рецептор, связанный с g-белком, и ее применение

Country Status (8)

Country	Link
EP (1)	EP1470420A4 (fr)
JP (1)	JP2005514934A (fr)
BR (1)	BR0307122A (fr)
CA (1)	CA2473707A1 (fr)
MX (1)	MXPA04007117A (fr)
NO (1)	NO20043123L (fr)
RU (1)	RU2004125608A (fr)
WO (1)	WO2003061365A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004083388A2 (fr)	2003-03-14	2004-09-30	Bristol-Myers Squibb Company	Polynucleotide codant un nouveau variant de recepteur de hm74, hgprbmy74 couple a une proteine g humaine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1230361A2 (fr) *	1999-10-27	2002-08-14	PHARMACIA & UPJOHN COMPANY	Recepteurs couples par des proteines g exprimes dans le cerveau
IL149569A0 (en) *	1999-11-17	2002-11-10	Arena Pharm Inc	Endogenous and non-endogenous versions of human g protein-coupled receptors
EP1292677A2 (fr) *	2000-06-05	2003-03-19	Bayer Aktiengesellschaft	Regulation du recepteur couple a la proteine humaine g de type hm74

2003
- 2003-01-21 BR BR0307122-7A patent/BR0307122A/pt not_active IP Right Cessation
- 2003-01-21 EP EP03710699A patent/EP1470420A4/fr not_active Withdrawn
- 2003-01-21 MX MXPA04007117A patent/MXPA04007117A/es unknown
- 2003-01-21 WO PCT/US2003/001694 patent/WO2003061365A2/fr not_active Ceased
- 2003-01-21 CA CA002473707A patent/CA2473707A1/fr not_active Abandoned
- 2003-01-21 JP JP2003561321A patent/JP2005514934A/ja active Pending
- 2003-01-21 RU RU2004125608/15A patent/RU2004125608A/ru not_active Application Discontinuation
2004
- 2004-07-20 NO NO20043123A patent/NO20043123L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2473707A1 (fr)	2003-07-31
EP1470420A2 (fr)	2004-10-27
MXPA04007117A (es)	2005-02-25
JP2005514934A (ja)	2005-05-26
EP1470420A4 (fr)	2005-08-24
BR0307122A (pt)	2004-12-28
WO2003061365A3 (fr)	2003-11-13
WO2003061365A2 (fr)	2003-07-31
NO20043123L (no)	2004-07-20

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Legal Events

Date	Code	Title	Description
2006-05-10	FA93	Acknowledgement of application withdrawn (no request for examination)	Effective date: 20060327